Changes in Incidences of Chronic and Traumatic Diseases before and after Registration as Visually Disabled

Purpose: To analyze changes in the incidences of chronic and traumatic diseases before and after registration as visually disabled.Methods: The incidence and risk of chronic and traumatic diseases were compared between patients registered as visually disabled from 2005 to 2013 and a control group, selected through 1:1 propensity score matching for age, sex, premium quantile, and residential area distribution. Data from the National Health Insurance Service were used and the observation period was set from 2 years before to 5 years after the time of registration as visually disabled. The incidences (%) of chronic and traumatic diseases at the point of interest were determined as the mean values according to year of registration, and the risk was measured by conditional logistic regression analysis.Results: 131,434 visually disabled patients and the same number of non-visually impaired controls were included. The incidences of chronic disease and fall-related injury were higher in the visually disabled group before registration, but gradually decreased and became similar to the control group after registration. In addition, the risk of developing chronic diseases was higher in the visually disabled group until 2 years after registration, while the risk of fall-related injury remained consistently higher in the visually disabled group during the observation period. The incidence and risk of hip fracture in the visually disabled group increased gradually from approximately 1 year before registration and remained consistently higher than in the control group.Conclusions: People with visual disability have higher incidences of chronic diseases than do non-visually impaired people and are at greater risk of traumatic injuries, such as hip fractures or falls. There is a need to establish community infrastructure and expand welfare services for the prevention and early treatment of comorbidities, both for patients with registered visual disabilities and for patients who have not yet registered.

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Changes in Platelet Aggregability after Ovariectomy

Thrombosis and Haemostasis ◽

10.1055/s-0038-1657029 ◽

1979 ◽

Vol 42 (04) ◽

pp. 1332-1339 ◽

Cited By ~ 7

Author(s):

Hiroh Yamazaki ◽

Takeshi Motomiya ◽

Minoru Sonoda ◽

Noboru Miyagawa

Keyword(s):

Platelet Count ◽

Platelet Activation ◽

Ovarian Hormones ◽

Control Group ◽

Platelet Aggregability ◽

Appearance Rate ◽

Before And After ◽

The Difference ◽

Induced Aggregation ◽

Observation Period

SummaryChanges in platelets in 48 patients with uterine myoma before and after hysterectomy with and without ovariectomy were examined. Bilateral ovariectomy in 25 cases (ovariec-tomized group) and unilateral or non-ovariectomy in 23 cases (control group) were performed at the hysterectomy. Platelet count and an appearance rate of secondary aggregation decreased at one day after and increased at one week after the operation, similarly in both the ovariectomized and the control group. The appearance rate of secondary aggregation was reflected in an intensity of aggregation at 5 min after the addition of reagent to PRP. At one month after the operation, the appearance rate of secondary aggregation induced by 3 μM ADP showed a statistically significant decrease in comparison with the preoperation value (P <0.05) and the enhancement of 5-min aggregation was still observed in the control group, while ceased in the ovariectomized group. The difference between the two groups was significant (P < 0.05). There was almost no change in the speed and intensity of primary and secondary aggregation during the observation period. No significant differences in collagen-induced aggregation were noted between the two groups. The results suggest that ovarian hormones, mainly estrogen, facilitate platelet activation which is mediated by the so-called secondary aggregation.

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A randomized, placebo-controlled trial of intravenous gammaglobulin in alloimmunized thrombocytopenic patients

Blood ◽

10.1182/blood.v75.1.313.313 ◽

1990 ◽

Vol 75 (1) ◽

pp. 313-316 ◽

Cited By ~ 45

Author(s):

T Kickler ◽

HG Braine ◽

S Piantadosi ◽

PM Ness ◽

JH Herman ◽

...

Keyword(s):

Platelet Transfusion ◽

Controlled Trial ◽

Parameter Estimate ◽

Control Group ◽

Platelet Recovery ◽

Mean Values ◽

Blinded Study ◽

Before And After ◽

Study Population ◽

Intravenous Gammaglobulin

Abstract In a placebo-controlled, randomized blinded study, we evaluated the efficacy of intravenous gammaglobulin (IV-IgG) in alloimmunized thrombocytopenic patients. IV-IgG was administered at a dose of 400 mg/kg for 5 days. An incompatible platelet transfusion from the same donor was used before and after treatment. Seven patients received IV- IgG and five patients received placebo. Although platelet recovery in 1 to 6 hours was satisfactory in five patients after IV-IgG treatment, 24- hour survival was not improved in most patients. None of the patients receiving the placebo achieved satisfactory 1-hour platelet-corrected count increments (CCIs). By t test, the posttreatment mean values 1 hour after transfusion CCIs in the IV-IgG group were significantly greater than in the control group (8,413 v 1,050, P less than .007). Using a regression model to adjust for any distributional assumptions of the study population, the parameter estimate for IV-IgG treatment was positive, indicating that IV-IgG treatment is associated with higher CCIs. Although IV-IgG may improve 1-hour platelet recovery, clinical benefit was not demonstrated since 24-hour survival was not improved. IV-IgG treatment before unmatched platelet transfusions should not be considered as a replacement for HLA-compatible platelets in alloimmunized patients.

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Effect of whitening dentifrices on the surface roughness of a nanohybrid composite resin

European Journal of Dentistry ◽

10.4103/1305-7456.178305 ◽

2016 ◽

Vol 10 (02) ◽

pp. 170-175 ◽

Cited By ~ 2

Author(s):

Gabriela Migliorin da Rosa ◽

Luciana Mendonça da Silva ◽

Márcio de Menezes ◽

Hugo Felipe do Vale ◽

Diego Ferreira Regalado ◽

...

Keyword(s):

Surface Roughness ◽

Composite Resin ◽

Wilcoxon Test ◽

Control Group ◽

Mean Values ◽

Short Period ◽

Significant Difference ◽

Before And After ◽

Nanohybrid Composite ◽

One Way Anova

ABSTRACT Objectives: The present study verified the influence of whitening dentifrices on the surface roughness of a nanohybrid composite resin. Materials and Methods: Thirty-two specimens were prepared with Filtek™ Z350 XT (3M/ESPE) and randomly divided into four groups (n = 08) that were subjected to brushing simulation equivalent to the period of 1 month. The groups assessed were a control group with distilled water (G1), Colgate Total 12 Professional Clean (G2), Sensodyne Extra Whitener Extra Fresh (G3), and Colgate Luminous White (G4). A sequence of 90 cycles was performed for all the samples. The initial roughness of each group was analyzed by the Surface Roughness Tester (TR 200-TIME Group Inc., CA, USA). After the brushing period, the final roughness was measured, and the results were statistically analyzed using nonparametric Kruskal–Wallis and Dunn tests for intergroup roughness comparison in the time factor. For intragroup and “Δ Final − Initial” comparisons, the Wilcoxon test and (one-way) ANOVA were, respectively, performed (α = 0.05). Results: The roughness mean values before and after brushing showed no statistically significant difference when the different dentifrices were used. None of the dentifrices analyzed increased significantly the nanohybrid composite resin surface roughness in a 1 month of tooth brushing simulation. Conclusions: These results suggest that no hazardous effect on the roughness of nanohybrid composite resin can be expected when whitening dentifrices are used for a short period. Similar studies should be conducted to analyze other esthetic composite materials.

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INFLUENCE OF GROWTH IN TREATED CLASS III GROWING PATIENTS WITH FACE MASK THERAPY AND UNTREATED PATIENTS

Knowledge International Journal ◽

10.35120/kij3104883c ◽

2019 ◽

Vol 31 (4) ◽

pp. 883-888

Author(s):

Sofija Carceva Shalja ◽

Sandra Atanasova

Keyword(s):

Negative Impact ◽

Face Mask ◽

Treated Group ◽

Control Group ◽

Class Iii ◽

Class Iii Malocclusion ◽

Maxillary Protraction ◽

Before And After ◽

Maxillary Deficiency ◽

Observation Period

Developing Class III Malocclusion in most of the cases affects dentofacial appearance. The goal of this study is to investigate the changes in the facial appearances in treated patients withFace mask orthopedic treatment and untreated Class III patients. The sample consisted 49 patients (boys and girls),with average age of 9 years, who had a Class III Malocclusion with an anterior crossbite and a component of maxillary deficiency. 28 of them were treated with protraction Face mask- Delair mask (petit tipe), and the other 21 were presenting the control group consisted of untreated Class III Patients.In treated group pretreatment and posttreatment cephalometric radiographs from 28 patients(15 males and 13 females) were analyzed and compared with the results of cephalometric analyzes in untreated group(observation period of 1 year). Results from these study showed forward displacement of maxilla(SNA p<0.05),increasing of maxillary length(Co-A p<0.05)correction of maxillary-mandibular relationship(ANB p<0.05) in treated group while in untreated groupvalues for the parameters in the upper jaw and inter jaw relationship before and after the observation period of 1 yearshowed no statistically significant changes pointing to the negative impact of incorrect skeletal terms in Class III growing patients.Based on our findings we can concluded that in Class III patients there is a big motivation for orthodontic treatment because their dentofacial appearance deviates from sociocultural norms.Therefore, an important objective of accepting maxillary protraction treatment in Class III malocclusion is providing nonsurgical alternative in the treatment and improving the physico-social wellbeing and appearance of the patients, especially during their teenage years.

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Prospective study of dentoskeletal changes in Class II division malocclusion treatment with twin force bite corrector

The Angle Orthodontist ◽

10.2319/042312-339.1 ◽

2012 ◽

Vol 83 (2) ◽

pp. 319-326 ◽

Cited By ~ 8

Author(s):

Carlos Henrique Guimarães ◽

José Fernando Castanha Henriques ◽

Guilherme Janson ◽

Marcio Rodrigues de Almeida ◽

Janine Araki ◽

...

Keyword(s):

Class Ii ◽

Control Group ◽

Facial Growth ◽

Lateral Cephalograms ◽

Before And After ◽

Group 2 ◽

In The Beginning ◽

Experimental Group ◽

Observation Period ◽

Mandibular Incisors

ABSTRACT Objective: To evaluate the dentoskeletal changes of Class II malocclusion treatment with the Twin Force Bite Corrector (TFBC). Materials and Methods: The sample comprised 86 lateral cephalograms obtained from 43 subjects with Class II division 1 malocclusion; the subjects were divided into two groups. The experimental group comprised 23 patients with a mean initial age of 12.11 years who were treated with the TFBC for a mean period of 2.19 years. The control group included 40 lateral cephalograms from 20 Class II nontreated patients, with an initial mean age of 12.55 years and a mean observation period of 2.19 years. The lateral cephalograms were evaluated before and after orthodontic treatment in group 1 and in the beginning and end of the observation period in group 2. t-Tests were used to compare the initial and final cephalometric characteristics of the groups as well as the amount of change. Results: The experimental group presented greater maxillary growth restriction and mandibular retrusion than the control group, as well as greater maxillomandibular relationship improvement and greater labial tipping of the mandibular incisors. The results also showed a greater decrease in overbite and overjet in the experimental group, and there were no statistically significant differences in the craniofacial growth pattern between groups. Conclusions: The TFBC promotes restriction of anterior maxillary displacement without significant changes in mandibular length and position and improvement of maxillomandibular relationship without changes in facial growth and significant buccal tipping of mandibular incisors. Class II correction with the TFBC occurred primarily as a result of dentoalveolar changes.

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Effects of Anti-Allergic Drugs on Substance P (SP) and Vasoactive Intestinal Peptide (VIP) in Nasal Secretions

American Journal of Rhinology ◽

10.2500/105065897781751901 ◽

1997 ◽

Vol 11 (3) ◽

pp. 237-242 ◽

Cited By ~ 25

Author(s):

Mitsunori Shinoda ◽

Noritake Watanabe ◽

Takeshi Suko ◽

Goro Mogi ◽

Masaharu Takeyama

Keyword(s):

Substance P ◽

Vasoactive Intestinal Peptide ◽

Total Protein ◽

Clinical State ◽

Control Group ◽

Nasal Allergy ◽

Protein Ratio ◽

Mean Values ◽

Before And After ◽

Nasal Secretions

To clarify the effects of anti-allergic drugs on substance P (SP) and vasoactive intestinal peptide (VIP) levels in nasal secretions, we employed competitive enzyme-linked immunoassays to measure concentrations of those neuropeptides in nasal secretions from 40 patients with house dust nasal allergy before and after administration of azelastine and oxatomide. One mg of azelastine and 30 mg of oxatomide were administrated twice a day for 4 weeks. Mean values of SP concentrations and ratios of SP to total protein of the nasal allergy group were significantly higher than those of the control group (p < 0.002). The VIP/total protein ratio of the allergy group was also significantly higher than that of the control group, although the VIP concentration alone was not. Mean levels of SP and VIP from patients with severe symptoms were significantly higher than those of the control group (p < 0.05), although those values were not significantly different between patients with moderate symptoms and control subjects. Azelastine and oxatomide effectively reduced SP levels in nasal secretions (p < 0.005), but they did not significantly decrease VIP levels. The reduction of SP levels was significant in patients with excellent responses to those drugs (p < 0.005), but not in patients with poor responses. These findings suggest that SP and VIP levels in nasal secretions may reflect the clinical state of nasal allergy and be one of the better parameters available for evaluating the clinical efficacy of anti-allergic drugs against nasal allergy.

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Lipid fractions in primary hyperparathyroidism before and after surgical cure

Acta Endocrinologica ◽

10.1530/acta.0.1020539 ◽

1983 ◽

Vol 102 (4) ◽

pp. 539-542 ◽

Cited By ~ 7

Author(s):

N. D. Vaziri ◽

L. Wellikson ◽

G. Gwinup ◽

C. Byrne

Keyword(s):

Primary Hyperparathyroidism ◽

Serum Lipids ◽

Control Group ◽

Lipid Levels ◽

Serum Triglycerides ◽

Mean Values ◽

Lipid Fractions ◽

Before And After ◽

Surgical Cure ◽

The Mean

Abstract. A number of previous studies has suggested that PTH may possess a hyperlipimic property. We determined various lipid fractions in 24 patients with primary hyperparathyroidism before and 1–3 months after surgical cure. The mean values for serum total cholesterol, triglycerides. LDL-Chol, VLDL-Chol and HDL-Chol did not change significantly with definitive correction of hyperparathyroidism. The mean values for all lipid fractions were comparable to those of the age and sex-matched normal control group except for HDL-Chol which was significantly lower in the hyperparathyroid group both before and after definitive cure of hyperparathyroidism. Only one patient with combined elevation of serum triglycerides and cholesterol exhibited normalization of the lipid levels after surgery. Two other patients with hypertriglyceridaemia failed to show any reduction in their triglyceride levels after correction of their hyperparathyroidism. Our data suggest that long-standing elevation of PTH to the extent seen in primary hyperparathyroidism and in the absence of predisposing conditions does not increase serum lipids in human.

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Efficiency of different instruments used for composite filling polishing.

Acta Stomatologica Marisiensis Journal ◽

10.2478/asmj-2021-0005 ◽

2021 ◽

Vol 4 (1) ◽

pp. 31-37

Author(s):

Andrea-Csinszka Kovacs-Ivacson ◽

Alexandra Mihaela Stoica ◽

Mónika Kovacs ◽

Mihai Pop

Keyword(s):

Surface Roughness ◽

Control Group ◽

Mean Values ◽

Significance Level ◽

Caries Treatment ◽

Before And After ◽

Long Time ◽

Surface Irregularities ◽

Surface Staining

Abstract Introduction: Improper finishing and polishing of fillings leads to surface roughness of the restoration which leads to excessive plaque accumulation, gingival irritation, increased surface staining and poor aesthetics of restored teeth. Therefore, it is essential to use polishing instruments and pastes as a final step of simple caries treatment in order to achieve optimal long-time results. The aim of this study is to evaluate the efficiency of 4 different finishing and polishing instruments used for surface smoothening of aesthetic restorative materials in vitro. Materials and methods: 40 composite (Reality X) samples were prepared in vitro. Their surface irregularities were measured along 3 diagonals before and after polishing. Sof-Lex discs (3M Espe), rubber cones (Kenda), Arkansas stone (Fino) and polishing paste and a professional toothbrush (Kerr) were used for polishing. Each sample was polished under 5N pressure for 30 seconds at 3000 rpm. The surface roughness was than measured using a profilometer. Statistic analysis was performed using ANOVA and unpaired T-tests, the significance level was set at a value of p<0.05. Results: Based on the mean values, the smallest roughness was found in the control group- 0.11, while the highest in the rubber polishers and Arkansas stone group- 0.47 and 0.48. The values for the Sof-Lex disc group and the polishing paste-toothbrush group were 0.40 and 0.39. Statistical analysis showed no significant differences between the four groups. Conclusion: It is mandatory to use polishing tools in order to obtain a smooth surface of the restoration and avoid the unwanted long-term complications. Polishing using brush and abrasive paste produced the smoothest surface of the composite.

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Psychogenic dyspnea and hypocapnia in men with ischemic heart disease before and after CABG

Patologiya krovoobrashcheniya i kardiokhirurgiya ◽

10.21688/1681-3472-2012-1-39-42 ◽

2018 ◽

Vol 16 (1) ◽

pp. 39

Author(s):

O. V. Grishin ◽

N. N. Averko ◽

V. G. Grishin ◽

I. G. Zhilina ◽

Yu. V. Kovalenko

Keyword(s):

Heart Disease ◽

Ischemic Heart Disease ◽

Coronary Revascularization ◽

Cardiovascular Effects ◽

Ischemic Heart ◽

Control Group ◽

Mean Values ◽

Healthy Men ◽

Before And After ◽

Revascularization Surgery

The goal of the study was to compare the rate of psychogenic dyspnea (PD) and hypocapnia in patients with ischemic heart disease (IHD) before and after CABG. We studied the objective signs of PD and hypocapnia, such as psychogenic dyspnea coefficient (PDC) and СО 2 concentration in the expired air finite portion (FetCО 2) in 47 male patients with IHD and 34 healthy men by using spirometry and capnometry. We also performed a comparative analysis of the above-mentioned parameters before and after CABG. The arrhythmic breathing rate (PDC>40) in patients with IHD was 2.6 times higher than that in healthy men, and the hypocapnia rate (FetCО 2<4.5%) was 3.6 times higher than that in the control group. The data obtained were confirmed by the group mean values of PDC and FetCО 2. Thus, PDC in the IHD cohort was significantly higher, and FetCО 2 lower than in healthy men (4.60.4 and 5.20.3 respectively, р<0.05). On the 8-10 th postoperative day there was a 1.3 times increase in patients with PDC>40, and a 1.7 times increase in hypocapnia patients, with the mean FetCО 2 level decreasing from 4.60.4 before surgery down to 4.00.7 after CABG (р<0,05). Thus, psychogenic dyspnea or neurogenic hyperventilation (NH), as well as the resulted hypocapnia, are documented in IHD patients. Because of its negative cardiovascular effects, NH requires timely diagnosis and correction before and after coronary revascularization surgery.

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Inhalation of Heparin and its Effect on Blood Coagulation

10.1055/s-0039-1687252 ◽

1979 ◽

Author(s):

M. Hellgren ◽

K. Hägnevik ◽

M. Blombäck

Keyword(s):

Dose Group ◽

Antithrombin Iii ◽

Control Group ◽

High Dose ◽

Thrombin Time ◽

Heparin Group ◽

Blood Samples ◽

Mean Values ◽

Heparin Concentration ◽

Observation Period

Heparin was administered by aerosol inhalation in principle according to Jaques et al. to 13 volunteers. The effects were investigated with activated partial thromboplastin tune (APT-time), thrombin-time and antithrombin III (Odegaard. Heparin concentration was measured in plasma according to Teien et al. and platelets were counted. Four volunteers received 700-800 IU heparin and 9, 1300 IU/kg b.w. Blood samples were drawn before, after and once a day for 10 to 21 days. Controls inhaled normal saline and blood samples were drawn for 12 days. No untowards effects were noted either on the day of inhalation or during observation period.On the day of inhalation heparin concentration in plasma increased in the heparin-group but not in the control group. A maintained level of heparin was measured up to 3 weeks afterwards in 9 of the 13 volunteers. The heparin concentrations increased fren mean values of 0.014 IU/ml plasma to a maximal mean value of 0.040 IU/ml plasma in the high dose and 0.039 IU/ml plasma in the low dose group. During the observation period heparin mean level was about 0.020 to 0.030 lu/ml plasma in the heparin group. In the control troup there was no measurable heparin. The APT and thrombin times were prolonged during the day of inhalation in the high-dose but not in the lew-dose group. Antithrombin III and ptc remained unchanged in both groups and no changes were noted in the control group.

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