scholarly journals Influence of calcium concentrations on the metabolic profile of dairy goats during the transitional period

2021 ◽  
Vol 10 (11) ◽  
pp. e308101119462
Author(s):  
Jobson Filipe de Paula Cajueiro ◽  
Rodolfo José Cavaltanti Souto ◽  
Elizabeth Hortêncio de Melo ◽  
Cleyton Charles Dantas Carvalho ◽  
Rafael José da Silva ◽  
...  
Keyword(s):  
Metabolic Profile ◽  
Protein Profile ◽  
Transitional Period ◽  
Gamma Glutamyl Transferase ◽  
Total Calcium ◽  
Dairy Goats ◽  
Nonesterified Fatty Acids ◽  
Subclinical Disease ◽  
Calcium Phosphorus ◽  
Glutamyl Transferase

In order to differentiate groups of hypocalcemic (G1) and normocalcemic animals (G2) and infer the influence of subclinical hypocalcemia on metabolic profiles, this study determined calcium concentrations during the transitional period in 35 dairy goats healthy, pregnant, primiparous or multiparous, crossbreed or pure-bred dairy goats producing average 3 kg/day/goat. Therefore, blood samples were collected before (30, 20 and 10 days before parturition), on the day of delivery and after parturition (10, 20, 30, 40, 50 and 60 days postpartum). The variables measured were glucose, nonesterified fatty acids, β-hydroxybutyrate, cholesterol, triglycerides, amylase, total protein, albumin, urea, creatinine, aspartate aminotransferase, gamma glutamyl transferase, creatine kinase, total calcium, phosphorus, magnesium, chlorides, cortisol and insulin, as well as ionized calcium (Ca++), sodium and potassium. Goats were considered to have subclinical hypocalcemia if Ca++ ≤0.72 mmol/L. The data were analyzed by ANOVA. In subclinically hypocalcemic goats, serum concentrations of Ca++ decreased earlier (10dbp) than in normocalcemic goats (parturition) and remained lower throughout the transitional period (p=0,004). Among the measured variables, Ca++ showed greater influence on the NEFA, glucose, insulin and total calcium but also influenced the protein profile. Lower food intake by goats with subclinical hypocalcemia was one of the main factors interfering with the metabolic profile and likely the productivity of these animals. Studies should be conducted to measure the effects of subclinical disease on the production rates and on the emergence of other transitional period diseases.

scholarly journals Metabolic profile of lactating goats fed integral mango meal

2015 ◽  
Vol 16 (4) ◽  
pp. 885-892
Author(s):  
Janaina de Lima SILVA ◽  
Adriana GUIM ◽  
Francisco Fernando Ramos de CARVALHO ◽  
Carla Wanderley MATTOS ◽  
Diogo Anastácio GARCIA ◽  
...  
Keyword(s):  
Experimental Design ◽  
Total Protein ◽  
Metabolic Profile ◽  
Latin Square ◽  
Gamma Glutamyl Transferase ◽  
Dairy Goats ◽  
Lactating Goats ◽  
Four Levels ◽  
Glutamyl Transferase ◽  
Forage:Concentrate Ratio

SUMMARY The work was conducted to evaluate the metabolic profile of lactating goats fed diets containing integral mango meal as a replacement for corn. Four levels of replacement (0, 33, 66 and 100%) were evaluated in diets with forage:concentrate ratio of 60:40. Eight crossbred multiparous lactating Saanen goats (48.72 ± 1.99 kg of BW) were introduced in the experiment 48 days postpartum and maintained up to 124 days of lactation. It was used a double Latin Square (4x4) experimental design, with four treatments, four periods and four animals per square. There was no effects (P>0.05) for the integral mango meal level on the intake of DM (1890 g/day), CP (278 g/day) and NDF (959 g/day). However, the intake of NFC and TDN decreased (P<0.05) 27.9 g/day and 0.082 kg/day, respectively, as the dietary integral mango meal increased. The concentrations of urea, creatinine, gamma glutamyl transferase, aspartate aminotransferase, albumin, total protein, glucose, triglycerides, total cholesterol, and magnesium were not altered (P>0.05) by replacement levels, with average values of 54.52 mg/dl, 0.71 mg/dl, 52.59 UI, 77.37 UI, 4.69 g/dl, 9.32 g/dl, 74.44 mg/dl, 40.10 mg/dl, 39.39 mg/dl, and 11.09 mg/dl, respectively. Considering the metabolic profile, mango meal whole can totally replace corn in diets of dairy goats.

scholarly journals Comparison of adiponectin levels and some metabolic parameters in dairy cows with subclinical and clinical ketosis

2018 ◽  
Vol 74 (1) ◽  
pp. 6047-2018 ◽  
Author(s):  
GULSAH AKGUL ◽  
ZAFER MECITOGLU ◽  
DUYGU UDUM KUCUKSEN ◽  
SEZGIN SENTURK
Keyword(s):  
Dairy Cows ◽  
Study Groups ◽  
Whole Body ◽  
Control Group ◽  
Gamma Glutamyl Transferase ◽  
Subclinical Ketosis ◽  
Study Selection ◽  
Early Postpartum ◽  
Calcium Phosphorus ◽  
Glutamyl Transferase

The aim of the presented study was to evaluate the relationship between adiponectin and non-esterified fatty acids (NEFA), β-hydroxybutyric acid (BHBA), glucose, albumin, Gamma-Glutamyl Transferase (GGT), calcium, phosphorus and Blood Urea Nitrogen (BUN) levels in healthy cows and cows suffering clinical or subclinical ketosis in the early postpartum period. A total of 45 Holstein-Fresian dairy cows, consisting of 15 with clinical ketosis, 15 with subclinical ketosis and 15 healthy controls, was used in the study. Selection of animals was based on blood BHBA levels and urine ketone strip results on day 7 after parturition. Blood adiponectin, NEFA, glucose, albumin, GGT, calcium, phosphorus and BUN were also measured on day 7 postpartum. Adiponectin levels were significantly lower in both Clinical Ketosis and Subclinical Ketosis groups compared to the control group. NEFA levels were higher and glucose and calcium levels were lower in both ketosis groups when compared to the control animals. On the other hand, blood albumin, GGT, phosphorus and BUN levels did not differ among study groups. Based on the results of the study, it can be stated that adiponectin may play a role in the pathogenesis of ketosis. This role could be lower milk yield and better energy balance in early postpartum dairy cows with high adiponectin levels due to increased whole body tissue insulin sensitivity..

scholarly journals Serum biochemistry profile in newborn Senepol and crossbred Holstein x Gir calves aged three to five days in Uberlândia, Minas Gerais, Brazil

2016 ◽  
Vol 37 (3) ◽  
pp. 1415
Author(s):  
Lara Reis Gomes ◽  
Renata Dias Rodrigues ◽  
Rafael Rocha de Souza ◽  
Amanda Bizare ◽  
João Gabriel Knychala Faria ◽  
...  
Keyword(s):  
Total Protein ◽  
Serum Biochemistry ◽  
Blood Parameters ◽  
Minas Gerais ◽  
Gamma Glutamyl Transferase ◽  
Serum Concentrations ◽  
Male And Female ◽  
Calcium Phosphorus ◽  
Glutamyl Transferase ◽  
Physiological Variations

This study aimed to evaluate the physiological variations in the serum biochemical profile of neonate (3-5 days old) Senepol and crossbreed Holstein x Gir calves in Uberlândia, state of Minas Gerais, Brazil, and to compare values between breeds and sexes. In total, 168 healthy Senepol (n = 80, 28 females and 52 males) and crossbred Holstein x Gir (n = 88, 49 females and 39 males) calves were evaluated. From each animal, approximately 5 mL of blood was collected by jugular venipuncture into a sterile tube without anticoagulant to obtain serum. Serum concentrations of total protein, albumin, creatinine, urea, total cholesterol, triglycerides, calcium, and phosphorus; and the activities of alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase, and gamma-glutamyl transferase (GGT) were determined on a automated multichannel analyzer. There were significant differences (p &lt; 0.05) in serum concentrations for total protein, globulin, albumin/globulin ratio (A:G), creatinine, urea, phosphorus, calcium/phosphorus ratio (Ca:P), AST, and GGT between Senepol calves and crossbred Holstein x Gir calves, but no significant differences in serum concentrations were observed between male and female calves for either breed (p &gt; 0.05). It was concluded that the serum biochemistry profile of newborn Senepol and crossbred Holstein x Gir calves was affected by differences in colostrum intake management and breed characteristics. Also, no differences in blood parameters were observed between male and female calves.

scholarly journals Impact of the ovarian cycle and pregnancy on plasma chemistry values in ewes

2018 ◽  
Vol 30 (2) ◽  
pp. 238-244 ◽  
Author(s):  
Micaela E. Zywicki ◽  
Sharon E. Blohowiak ◽  
Ronald R. Magness ◽  
Jeffrey L. Segar ◽  
Pamela J. Kling
Keyword(s):  
Veterinary Medicine ◽  
Total Protein ◽  
Plasma Chemistry ◽  
Reference Intervals ◽  
Ovarian Cycle ◽  
Late Gestation ◽  
Reproductive Age ◽  
Gamma Glutamyl Transferase ◽  
Calcium Phosphorus ◽  
Glutamyl Transferase

Normative data for plasma chemistry values in pregnant and non-pregnant reproductive age ewes are scant. Availability of data would aid monitoring of ewe health for both research and veterinary medicine. We determined specific plasma chemistry 95% confidence reference intervals (RIs) in non-pregnant and pregnant ewes. Mixed Western-breed ewes were grouped based on phase of ovarian cycle: luteal ( n = 15), follicular ( n = 17), or late-gestation pregnant ( n = 102). Plasma samples were collected for analysis on a commercial biochemical analyzer. For RIs, chemistry panels for the 3 groups of ewes included nutrients and metabolites (glucose, triglycerides, cholesterol, urea, creatinine, total protein, albumin, and bilirubin), enzymes (lactate dehydrogenase, aspartate transaminase, gamma-glutamyl transferase, alanine aminotransferase, and alkaline phosphatase [ALP]), and micronutrients (calcium, phosphorus, iron, sodium, potassium, and chloride). Sample chemistry values for glucose and total protein in pregnant ewes were lower than in follicular ewes; cholesterol was lower in pregnant and luteal ewes than in follicular ewes. In addition, total bilirubin in pregnant ewes differed from that in luteal ewes, and that in follicular ewes also differed from luteal ewes. ALP in pregnant ewes was higher than other groups; phosphorus in pregnant ewes was lower than in luteal ewes. Iron was higher in pregnant ewes than in luteal ewes, with iron in luteal ewes lower than in follicular ewes. These data provide clinical RIs comparing pregnant and non-pregnant ewes for use in monitoring ewe health in both human research and veterinary medicine.

scholarly journals Biochemical serum profile of quarter mile equines in team penning training

2020 ◽  
Vol 36 (5) ◽  
Author(s):  
Roberta de Lima Santos ◽  
Renata Dias Rodrigues ◽  
Lara Reis Gomes ◽  
Amanda Bizare ◽  
Wilson Junior Oliveira ◽  
...  
Keyword(s):  
Average Duration ◽  
Ionized Calcium ◽  
Serum Concentrations ◽  
Total Calcium ◽  
Total Proteins ◽  
Physical Exercises ◽  
Aspartate Amino Transferase ◽  
Before And After ◽  
Calcium Phosphorus ◽  
Glutamyl Transferase

The objective of this work was to evaluate the proteins, minerals, metabolites, and serum enzymes profile in Quarter Mile equines subjected to training for Team Penning competitions by comparing the results before and after training. The animals were from the Agricultural Exhibition Park of Uberlândia (CAMARU), in Uberlândia in the State of Minas Gerais, Brazil. These animals perform constant periodic training with an average duration of two and a half hours per training. Blood samples from twenty male and female equines were collected at the beginning and end of a 45-day interval and then analyzed. A 5 mL blood sample from each animal was collected before and after training by a jugular external venipuncture, and the samples were placed in a tube—without anticoagulant and containing separator gel—to obtain the serum. The components analyzed were: total proteins, albumin, globulins, albumin to globulin ratio (A:G), total and ionized calcium, phosphorus, calcium to phosphorus ratio (Ca:P), cholesterol, triglycerides, creatinine, urea, alkaline phosphatase, ɤ-glutamyl transferase, lactate dehydrogenase (LDH), aspartate amino transferase (AST), alanine aminotransferase (ALT) and creatine kinase (CK). Statistical differences were observed with higher values after exercise for total calcium, ionized calcium, Ca: P ratio, creatinine and ALT and decreased concentrations were found for globulins, phosphorus, cholesterol and triglycerides. Despite the changes observed in the serum concentrations of some elements after exercises, it was concluded that the animals were in adequate physical condition to perform the proposed physical exercises.

scholarly journals Effects of age and sex on blood biochemistry of dorper lambs

2017 ◽  
Vol 38 (5) ◽  
pp. 3085 ◽  
Author(s):  
Rebecca Espírito Santo da Cruz ◽  
Fernando Melo Rocha ◽  
Cassius Vinícius Barbosa Sena ◽  
Pablo Gomes Noleto ◽  
Ednaldo Carvalho Guimarães ◽  
...  
Keyword(s):  
Age Groups ◽  
Gamma Glutamyl Transferase ◽  
Low Density ◽  
Biochemical Variables ◽  
Blood Biochemical ◽  
Significant Difference ◽  
Calcium Phosphorus ◽  
Dorper Sheep ◽  
Glutamyl Transferase ◽  
High Density Cholesterol

The purpose of this study was to evaluate the physiological variations and influence of age group and sex on biochemical variables of 32 male and female Dorper sheep at the age of 15 to 121 days. Four blood samples were collected from each animal, at monthly intervals, totaling 128 samples. Biochemical variables determined in each sample were total protein (TP), albumin (ALB), globulin (GLB), albumin/globulin ratio (A/G), glucose (GLU), triglycerides (TG), total cholesterol (tCHOL), high density cholesterol carrying lipoproteins (HDL-C), low density cholesterol carrying lipoproteins (LDL-C), very low density cholesterol carrying lipoproteins (VLDL-C), urea, creatinine (CRE), total calcium (tCa), ionized calcium (iCa), phosphorus (P), calcium/phosphorus ratio (Ca/P), magnesium (Mg), sodium (Na), potassium (K), chloride (Cl), alanine aminotransferase (ALT), aspartate aminotransferase (AST), gamma-glutamyl transferase (GGT) and alkaline phosphatase (ALP). The results were obtained in four moments according to age: M1 - sheep from 15 to 30 days, M2 - sheep from 45 to 61 days, M3 - sheep from 74 to 90 days and M4 - sheep from 105 to 121 days. Comparing the values of the biochemical variables among the four age groups studied a significant difference (p < 0.05) was observed in the concentrations of all the variables evaluated except for Na, Cl and ALT. Sex did not influence (p > 0.05) the values of the biochemical variables analyzed. Based on the results, it is concluded that the age groups exert a significant influence on the majority of blood biochemical variables of Dorper sheep from 15 to 121 days of age.

scholarly journals Investigation of liver tissue and biochemical parameters of adult wistar rats treated with Arctium lappa L.

2009 ◽  
Vol 52 (2) ◽  
pp. 335-340 ◽  
Author(s):  
Fabrícia Souza Predes ◽  
Sérgio Luis Pinto da Matta ◽  
Juliana Castro Monteiro ◽  
Tânia Toledo de Oliveira
Keyword(s):  
Liver Tissue ◽  
Biochemical Parameters ◽  
Wistar Rats ◽  
Morphological Analysis ◽  
Morphological Data ◽  
Gamma Glutamyl Transferase ◽  
Arctium Lappa ◽  
Calcium Phosphorus ◽  
Male Wistar Rats ◽  
Glutamyl Transferase

This study was carried out to evaluate the effects of Arctium lappa L. (burdock) on the liver of adult male Wistar rats as measured by light microscopy and biochemical parameters. The rats received the extract in water bottles at doses of 10 or 20 g/L daily for 40 days. There were no significant changes in the plasma levels of albumin, aspartate transaminase (AST), alanine transaminase (ALT), gamma glutamyl transferase (GGT), total protein, total cholesterol, urea, uric acid, triacylglycerol, calcium, phosphorus, chlorine and direct bilirubin. The morphological analysis did not reveal histopathological alterations in liver tissue. Both biochemical and morphological data did not indicate A. lappa toxicity.

scholarly journals Evaluation of metabolic profiles of Saanen goats in the transition period

2020 ◽  
Vol 71 (2) ◽  
pp. 2127
Author(s):  
F. AKKAYA ◽  
S. SENTURK ◽  
Z. MECITOĞLU ◽  
S. KASAP ◽  
S. ERTUNC ◽  
...  
Keyword(s):  
Postpartum Period ◽  
Biochemical Parameters ◽  
Metabolic Profile ◽  
Transition Period ◽  
Gamma Glutamyl Transferase ◽  
Periparturient Period ◽  
Pregnancy Toxemia ◽  
Aspartate Amino Transferase ◽  
Glutamyl Transferase ◽  
And Control

Healthy Saanen goats (n=30) in periparturient period were used in the present study. Blood samples were collected 21, 14 and 7 days before parturition, at the time of birth and postpartum days 7, 14 and 21. Non-esterifiedfatty acids (NEFA), betahydroxy butyric acid (BHBA), Total protein (TP), albumin (ALB), blood urea nitrogen (BUN), creatinine (CREA) aspartate amino transferase (AST), gamma glutamyl transferase (GGT), sorbitol dehydrogenase (SDH), glucose (GLU), cholesterol (CHOL), triglyceride (TG), calcium (Ca), phosphorus (P), and magnesium (Mg) levels were evaluated. During the study period, NEFA, SDH, CREA levels increased and CHOL and TG levels decreased at time of parturition. When the changes of parameters in prepartum and postpartum period were compared, the concentrations of NEFA, CHOL, GLU, TG, Ca were higher (p <0.001) in prepartum period;however BHBA, Mg, ALB, GGT, AST, TP, P, BUN, SDH and CREA concentrations were detected to be higher (p <0.001) in postpartum period. Metabolic Profile Test based on biochemical parameters evaluated in our study would be beneficial for diagnosis, prevention and control of diseases such as pregnancy toxemia, hypocalcemia, infertility in goats.

Recovery from LCDD-associated Severe Liver Cholestasis: a Case Report and Literature Review

2016 ◽  
Vol 25 (1) ◽  
pp. 99-103 ◽  
Author(s):  
Benoit Brilland ◽  
Johnny Sayegh ◽  
Anne Croue ◽  
Frank Bridoux ◽  
Jean-François Subra ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Light Chain ◽  
Intrahepatic Cholestasis ◽  
Relevant Literature ◽  
Gamma Glutamyl Transferase ◽  
Light Chain Deposition Disease ◽  
Deposition Disease ◽  
Uncommon Presentation ◽  
Light Chain Deposition ◽  
Glutamyl Transferase

Light chain deposition disease (LCDD) is a rare multisystemic disorder associated with plasma cell proliferation. It mainly affects the kidney, but liver and heart involvement may occur, sometimes mimicking the picture of systemic amyloidosis. Liver disease in LCDD is usually asymptomatic and exceptionally manifests with severe cholestatic hepatitis. We report the case of a 66-year-old female with κ-LCDD and cast nephropathy in the setting of symptomatic multiple myeloma who, after a first cycle of bortezomib-dexamethasone chemotherapy, developed severe and rapidly worsening intrahepatic cholestasis secondary to liver κ-light chain deposition. Intrahepatic cholestasis was attributed to LCDD on the basis of the liver histology and exclusion of possible diagnoses. Chemotherapy was maintained and resulted in progressive resolution of cholestasis. We report here an uncommon presentation of LCDD, with prominent liver involvement that fully recovered with bortezomib-based chemotherapy, and briefly review the relevant literature. Abbreviations: AKI: Acute kidney injury; ALP: alkaline phosphatase; ALT: alanine aminotransferase; AST: aspartate aminotransferase; CMV: Cytomegalovirus; EBV: Epstein–Barr virus; GGT: gamma-glutamyl transferase; HSV: Herpes simplex virus; LC: light chain; LCDD: Light chain deposition disease; MIDD: Monoclonal immunoglobulin deposition disease; MM: Multiple myeloma.

Evaluation of Hematological and Biochemical Changes in Dromedary Camel during the Different Stages of Lactation

2020 ◽  
Vol 21 (3) ◽  
pp. 121-124
Author(s):  
Ahmed El-Sayed
Keyword(s):  
Organic Phosphorus ◽  
Hemoglobin Concentration ◽  
Controlled Study ◽  
Mean Corpuscular Hemoglobin ◽  
Dromedary Camel ◽  
Gamma Glutamyl Transferase ◽  
Corpuscular Hemoglobin ◽  
Stage Of Lactation ◽  
Group 2 ◽  
Glutamyl Transferase

Objective: To assess the potential hematobiochemical alterations in healthy dromedary camel during the different stages of lactation. Design: Randomized controlled study. Animals: Fifteen healthy female dromedary camels, with mean body weight of 499.6 kg and mean age of 20 years. Procedures: Camels were categorized into 3 groups' according to their stage of lactation: group 1, early lactation (1-3 months), group 2, mid-lactation (four-6 months) and group3, late lactation (≥ 7 months). Blood samples were collected from every animals for hematological and biochemical evaluation. Results: Total erythrocyte count (TEC), hemoglobin (Hb), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), total leukocytes (TLC), lymphocytes, neutrophils, monocytes, Calcium, glucose, aspartate aminotransferase (AST), alanine transaminase (ALT), gamma glutamyl transferase (GGT) and alkaline phosphatase (ALP) confirmed significant (p < 0.05) variation between different stages of lactation. However, non-notable (p > 0.05) dissimilarity were located in packed cell volume (PCV), mean corpuscular hemoglobin concentration (MCHC), in organic phosphorus (P), magnesium (Mg), cholesterol, total protein (TP), albumen, globulin, blood urea nitrogen (BUN) and creatinine kinase (CK) in the course of different ranges of lactation, Conclusion and clinical relevance: The results of this investigation may be useful as reference guide for dromedary camel to evaluate the metabolic health status at different stages of lactation.

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