An observational study describing dermoscopic features of common macular facial hyperpigmented skin lesions

Genital warts (GW) are mucosal or skin lesions caused by sexual transmission of human papillomavirus (HPV). This study estimates the frequency of GW cases in physicians’ clinics and physicians’ usual practices of GW referral and diagnosis in Peru. Participants in this study were a convenience sample of 100 physicians in five specialties: primary care (17), gynecology (37), urology (10), dermatology (31), and infectious diseases (5). Physicians completed a survey and daily log of all patients aged 18–60 years seen over ten days in their offices located in Peru. The survey recorded GW referral patterns and the daily log recorded patient demographic information and GW diagnosis. Among 12,058 patients, the annual GW prevalence (95% confidence interval [CI]) was 2.28% (2.02–2.56) and cumulative incidence (95% CI) was 1.60% (1.38–1.84). Physicians reported that most GW patients were direct consult (73.5% of male and 67.9% of females) and physicians treated most GW patients themselves (73.4% of males and 76.7% of females). As reported, the most common reasons for referring were ‘serious cases requiring more specialized treatment’ (73.2% of male and 72.2% of female) and ‘lack of resources to treat’ (26.8% of male and 27.8% of female). We conclude that GW cases are commonly seen by physicians in Peru.

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Prevalence of various dermatoses in pregnancy at a tertiary care centre in Moradabad, Uttar Pradesh, India: an observational study

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20190263 ◽

2019 ◽

Vol 8 (2) ◽

pp. 425

Author(s):

Shruti Uniyal ◽

Ritika Agarwal ◽

Nupur Nandi ◽

Pulkit Jain

Keyword(s):

Observational Study ◽

Low Socioeconomic Status ◽

Treatment Options ◽

Tertiary Care ◽

Liver Function Tests ◽

Skin Lesions ◽

Personal Hygiene ◽

Tertiary Care Centre ◽

Palmar Erythema ◽

In Pregnancy

Background: This was a prospective study which was done to observe various skin lesions in pregnancy and to determine the most likely causes and their incidence in antenatal patients, it was noticed that many women in our institute were having pregnancy related cutaneous complaints thus this observational study was carried out so that better preventive measures and treatment options could be provided to these patients.Methods: Study was conducted in out-patient department of Obstetrics and Gynaecology, TMU, Moradabad. All ANC cases between October 2017 to September 2018 having any type of dermatoses were included in the study irrespective of gestational age. 6348 patients appeared in OPD in the given time period out of which 1256 were included. In case of pruritus, liver function tests were done with USG whole abdomen and patients were reviewed by physician if required. Screening with VDRL, HCV, HbSAg and ELISA for HIV was done in all. Results were tabulated and analyzed.Results: 50.8% primi gravidas ,49.2% multi gravidas. age range 18-38 years. 29.3% presented in third trimester ,25.6% presented in second trimester. Physiological changes seen in all cases, 8.68% specific dermatoses of pregnancy. 40.4 % no complaints, 5.65% melasma, 90.8% hyperpigmentation, 94.6% linea nigra. Secondary areola 89.3%,striae 80.3% out of which 38.9%- primi gravidas and 41.40% -multi gravidas. 92.9% no change in hair density. Montgomery’s tubercles 30-50% of cases. spiders nevi 67%. No cases of palmar erythema. Pruritus gravidarum 38.53%. PUPPP 28.4%. Pemphigoid Gestationis 9.17%. Prurigo of pregnancy 18.34%. Pruritic folliculitis 1.8%. Eczema in pregnancy : pre-existing in 3.7% , out of which exacerbation 1, 3 unaffected. 3 chicken pox.1 filariasis.24 herpetic lesions (herpes simplex).1 scleroderma.17.27% pre-existing taenia infection . Scabies 20.46%.11 0.87% dual infection (scabies-taenia).Conclusions: This study highlights high prevalence of community acquired infections in our region like taenia, scabies giving rise to skin lesions in Antenatal women. Moreover, it highlights a probable association between the prevalence of skin lesions with factors like poor personal hygiene, overcrowding, low socioeconomic status, anaemia and poor nutritional status.

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Uremic Pruritus and associated factors in Chronic Dialysis Patients: An Observational Study in Western Nepal

Birat Journal of Health Sciences ◽

10.3126/bjhs.v5i3.33703 ◽

2020 ◽

Vol 5 (3) ◽

pp. 1224-1230

Author(s):

Ajay Kumar ◽

Saujan Subedi ◽

Abhisek Maskey ◽

Mohammad Asim ◽

Brijesh Sathian ◽

...

Keyword(s):

Observational Study ◽

Sleep Disturbance ◽

Associated Factors ◽

Elevated Serum ◽

Serum Levels ◽

Skin Lesions ◽

Diagnostic Value ◽

Chronic Dialysis ◽

Dialysis Patients ◽

Uremic Pruritus

Introduction: Pruritus is one of the well-recognized major skin derangements in patients with advanced renal failure and are usually without visible skin lesions. Only few studies have addressed this issue in Nepalese population. Objective:.The present study aims to identify the prevalence and associated factors of uremic pruritus in chronic dialysis patients in western Nepal. Methodology:A prospective observational study was conducted to include all chronic dialysis patients with uremic pruritus at the Manipal Teaching Hospital, Pokhara, Nepal over a period of one year (June 2018 and May 2019). Results: During the study period, a total of 59 patients were included in the study with mean age of 55.8±15.8years,of which 37 (63%) patients developed uremic pruritus. Statistically significant relationship betweenpresence of pruritus and pruritus severity with frequency of itching grade and sleep disturbance score among elderly (p=0.001) were observed The serum urea can predict uremic pruritus among elderly patients with a good diagnostic value. The multivariate analysis showed male gender, hypertension, elevated serum albumin and random blood sugarwere independent predictors of pruritus in patients undergoing chronic dialysis. Conclusions: Our findings demonstrate that higher proportion ofpatients undergoing chronic dialysis werediagnosed with uremic pruritus (63%) and occurrence of pruritus had association with frequency of itching grade and sleep disturbance score .The serum levels of urea may predict the occurrence of pruritus among elderly patients.Furthermore, a large multicenter study is warranted with longer follow up which may provide robust information on the burden of pruritus and its associated factors to guide appropriate management among elderly.

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Erythema Pernio-like in four Adolescents in the era of the Coronavirus-2 Infection

Reviews on Recent Clinical Trials ◽

10.2174/1574887115666201016153031 ◽

2020 ◽

Vol 15 ◽

Cited By ~ 1

Author(s):

Luigi Promenzio ◽

Fabio Arcangeli ◽

Elisabetta Cortis ◽

Elisa Sama ◽

Federico Longhini

Keyword(s):

Observational Study ◽

Pediatric Population ◽

Clinical Manifestations ◽

Skin Lesions ◽

Cutaneous Manifestation ◽

Variable Intensity ◽

Apical Portion ◽

Adolescent Population ◽

Nasal Swabs ◽

Novel Coronavirus

Background: Although epidemic, novel coronavirus (SARS-CoV-2) infection rarely affects pediatric population. However, in the last months an increasing number of Italian pediatricians has reported the occurrence of erythema pernio-like in children following a flu-like syndrome, after the outbreak of SARS-CoV-2 infection. Objective: To report cutaneous manifestation of SARS-CoV-2 infection in 4 adolescents. Methods: : Observational study reporting 4 adolescents with skin lesions, 2 weeks after the occurrence of a flu-like syndrome. Results: Fourteen days after a flu-like syndrome, adolescents exhibited skin lesions to toes and feet. These lesions were rounded, with blurred limits, with a 5-15 mm diameter, red-violaceous-bluish colored, sometimes resulting in bullous lesions in correspondence of the central or apical portion, which tended to be covered with blackish crusts after evolution. Lesions were also accompanied by pain of variable intensity and evolved within two or three weeks to self-resolution without particular sequelae. In two patients, pharyngeal and nasal swabs were negative for SARS-CoV-2 infection, at the presentation of skin lesions. After 2 months from clinical manifestations, patients were tested positive for SARS-CoV-2 antibodies. Conclusions: In pediatric and adolescent population, the occurrence of an erythema pernio-like after a flu-like syndrome could be associated to SARS-CoV-2 infection.

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Effects of bosentan on the skin lesions: an observational study from a single center in Japan

Rheumatology International ◽

10.1007/s00296-008-0789-z ◽

2008 ◽

Vol 29 (7) ◽

pp. 769-775 ◽

Cited By ~ 17

Author(s):

Masanori Funauchi ◽

K. Kishimoto ◽

H. Shimazu ◽

Y. Nagare ◽

S. Hino ◽

...

Keyword(s):

Observational Study ◽

Skin Lesions ◽

Single Center

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Skin lesions in children admitted to the paediatric intensive care unit: an observational study

European Journal of Pediatrics ◽

10.1007/s00431-011-1436-3 ◽

2011 ◽

Vol 170 (10) ◽

pp. 1263-1265 ◽

Cited By ~ 7

Author(s):

J. Henk Sillevis Smitt ◽

Job B. M. van Woensel ◽

Albert P. Bos

Keyword(s):

Intensive Care Unit ◽

Intensive Care ◽

Observational Study ◽

Paediatric Intensive Care Unit ◽

Skin Lesions ◽

Paediatric Intensive Care

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Transportation of cull sows-a descriptive study of the clinical condition of cull sows before transportation to slaughter

Translational Animal Science ◽

10.1093/tas/txy057 ◽

2018 ◽

Vol 2 (3) ◽

pp. 280-289 ◽

Cited By ~ 4

Author(s):

Katrine K Fogsgaard ◽

Mette S Herskin ◽

Karen Thodberg

Keyword(s):

Observational Study ◽

Clinical Examination ◽

Clinical Condition ◽

Descriptive Study ◽

Skin Lesions ◽

Superficial Skin ◽

Lactating Sows ◽

Council Regulation ◽

Scientific Attention ◽

Cull Sows

Abstract Each year 500.000 sows, equal to 50% of Danish sows, are culled and transported to slaughter. However, the clinical condition, behavior, and welfare of cull sows have received almost no scientific attention. The aim of the current observational study was to describe the clinical condition of cull sows on the day of transportation to slaughter, including examination of possible differences between lactating and nonlactating sows. On the day of transportation, the participating farms were visited by trained technicians who conducted a thorough clinical examination of all sows selected by the farmer for slaughter. Four sows could not be transported because they were unfit according to the European Council Regulation regarding fitness for transportation, and they were not included in the present data. A total of 522 sows, with a median parity of 5 (range: 1–11), from 12 Danish farms were included in the study. Approximately, 10% showed signs of changed gait, and 0.8% were obvious lame. Wounds were observed in 54.6% of the sows, and 11% had decubital shoulder ulcers. Almost 40% of the cull sows were lactating. At culling, the lactating sows were of higher parity than the nonlactating sows, and lactating sows were at higher risk of having deviations from normal on clinical variables related to examination of the udder, such as udder swellings and inflammations. Nonlactating sows had 3.5 times more superficial skin lesions than lactating sows. Our findings warrant for further studies exploring different aspects of the life of cull sows in what is here defined as the The Cull Period, which is the interval from the culling decision is made until the sows are slaughtered

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Chronic generalized pruritus without primary skin lesions: a longitudinal prospective observational study

International Journal of Dermatology ◽

10.1111/ijd.14125 ◽

2018 ◽

Vol 58 (3) ◽

pp. 273-278 ◽

Cited By ~ 2

Author(s):

Narges Alizadeh ◽

Seyyed Hossein Mirpour ◽

Razieh Golmohamadi ◽

Abbas Darjani ◽

Hojat Eftekhari ◽

...

Keyword(s):

Observational Study ◽

Prospective Observational Study ◽

Skin Lesions ◽

Primary Skin Lesions

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Mucocutaneous manifestations in newborn: a study from tertiary care centre, Karnataka

International Journal of Research in Dermatology ◽

10.18203/issn.2455-4529.intjresdermatol20190482 ◽

2019 ◽

Vol 5 (2) ◽

pp. 346

Author(s):

T. Virupakshappa ◽

K. Sindhuri ◽

Anant A. Takalkar

Keyword(s):

Observational Study ◽

Neonatal Period ◽

Tertiary Care ◽

Skin Lesions ◽

Care Centre ◽

Tertiary Care Centre ◽

Parental Concern ◽

Cross Sectional ◽

Medical College ◽

High Prevalence

Background: The spectrum of dermatological manifestations in neonates varies from era to era and country to country. Skin lesions in neonatal period vary from transient self-limiting conditions to serious dermatoses, requiring specific therapies. Skin lesions are extremely common in newborns and can be a significant source of parental concern. The objective of the study was to study various mucocutaneous lesions in newborn babies.Methods: The present descriptive cross sectional observational study was conducted in department of dermatology, Navodaya Medical College, Raichur. A total 500 neonates were included in the study from January 2012 to September 2013. Data collected and analysed by using SPSS 16.0 version.Results: Prevalence of skin lesions in this study was found to be 97.4%. Maximum skin lesions were observed in 47 subjects (9.4%). Prevalence of Epstein pearls was 58%, Mongolian spots 53.6% and erythema toxicum neonatorum was 28%. Epstein pearls (males 60.2%, female 55.7%) and Mongolian spots (males 53.9%, females 53.3%) predominated.Conclusions: Prevalence of mucocutaneous skin lesions in newborn babies was 97.4%. High prevalence of Epstein pearls (58%), Mongolian spots (53.6%) and erythema toxicum neonatorum (28.6%) were observed.

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Factors Associated with Multibacillary Leprosy in a Priority Region for Disease Control in Northeastern Brazil: A Retrospective Observational Study

Journal of Tropical Medicine ◽

10.1155/2019/5738924 ◽

2019 ◽

Vol 2019 ◽

pp. 1-7 ◽

Cited By ~ 2

Author(s):

Maria Aparecida Alves de Oliveira Serra ◽

Crislane da Silva Santos ◽

Pedro Martins Lima Neto ◽

Karyne Gleyce Zemf Oliveira ◽

Francisca Jacinta Feitoza de Oliveira ◽

...

Keyword(s):

Observational Study ◽

Public Health Problem ◽

Secondary Data ◽

Skin Lesions ◽

Northeastern Brazil ◽

Retrospective Observational Study ◽

Important Public Health Problem ◽

Factors Associated ◽

Age Range ◽

Multibacillary Leprosy

Background. Leprosy is an infectious disease that can lead to physical disabilities and stigmatization. It remains an important public health problem, especially in Brazil.Objective. To analyse sociodemographic and clinical factors associated with multibacillary leprosy in a hyperendemic region of the disease in northeastern Brazil.Method. This is a retrospective observational study with secondary data acquired from 2012 to 2015, from a group of leprosy cases reported in a reference outpatient clinic for the treatment and followup of leprosy in the city of Imperatriz, Maranhao, in northeastern Brazil.Results. From 905 new cases of leprosy studied, 656 (72.5%) were classified as multibacillary leprosy and 249 (27.5%) as paucibacillary leprosy. We observed that men were more likely to present 5 to 15 skin lesions (OR: 1.32; 95% CI: 1.18-1.49; p <0.0001) and >15 skin lesions (OR: 1.26; 95% CI: 1.09 -1.45; p = 0.005) and a lower chance of having <5 skin lesions (OR: 0.67; 95% CI: 0.59-0.76; p <0.0001). Women were more likely to have no affected nerves compared to men (OR: 1.46; 95% CI: 1.20-1.77; p <0.0001). The age range of 16 to 60 years showed a greater chance of having <5 skin lesions (OR: 1.01; 95% CI: 1.007-1.20; p = 0.03) and a lower chance of having 5 to 15 skin lesions (OR: 1.12, 95% CI: 1.03-1.23; p= 0.008) and a lower chance of being a grade I disability ( CI= 0.73-0.94; p=0.83) and II (OR: 0.82; 95% CI: 0.77-0.98; p=000.1).Conclusion. Cases of multibacillary leprosy were associated with male gender, low educational level, and clinical variables such as number of skin lesions and grade I or II disability.

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