Comparative Assessment of the Dynamics of Immunological Reactivity in Patients With Postoperative Ventral Hernia

Postoperative Ventral Hernias to this day remain one of the main pathologies of planned and urgent surgical interventions. The purpose of the study is to study the immune response in patients with postoperative ventral hernias who underwent auto and alloplastic hernioplasty methods. The study included 40 patients diagnosed with postoperative ventral hernia, including 25 men (62.25%) and 15 women (37.5%). In men, the average age was 45.6±2.3 years, and in women 57.2±3.2 years. Patients are divided into 2 groups. Group I are patients who underwent autoplastic methods and group II patients who underwent alloplastic hernioplasty methods. The complex of immunological examination included the determination of a subpopulation of lymphocytes with CD3, CD4, CD8, CD20 receptors, interleukin 6, interleukin 10 and immunoglobulins A, M, G. Immunological examination of blood parameters in patients with postoperative ventral hernias revealed the following changes. There is an upward trend in all indicators. In group I, the leukocyte level was increased by +0.2±0.01, and in group II, the indicators were within the normal range. The level of monocytes in patients who underwent alloplasty increased by +1.5±0.2. There was an increase in the concentration of T and B lymphocytes with GD3, CD4, CD8, CD20 receptors on the 7th day after surgery in patients of the first group was +1.85±0.3, +1.6±0.4, +1.6±0.1, +1.5±0.2. And in patients of the second group, the initial level of indicators was lower and increased by +1.2±0.1, +1.4±0.2, +1.67±0.65, +1.03±0.45. The level of IL6 and IL 10 in the postoperative period increased in patients of the first group by +1.55±0.2 and +1±0.9, in the second group it was IL 6 +0.9±1.2, IL 10 +0.8±1.2. The study shows that the indicators of the humoral cell type tended to increase, which shows the result. Conclusions. Patients with postoperative ventral hernias who have undergone autoplastic and alloplastic hernioplasty methods in dynamics, the immunological reactivity indicators significantly increase on the 7th day, in comparison with the initial blood parameters. Namely, in patients who have undergone autoplastic methods of hernioplasty. The use of conventional suture materials in autogernioplasty increases the risk of developing an inflammatory process in the early and long-term postoperative period, in contrast to the use of polypropylene mesh prostheses.

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Results of observation of the postoperative period in patients with surgical aortic pathology after surgical intervention using cardiopulmonary bypass

Reports of Vinnytsia National Medical University ◽

10.31393/reports-vnmedical-2019-23(2)-16 ◽

2019 ◽

Vol 23 (2) ◽

pp. 267-276

Author(s):

K. A. Khyzhniak ◽

Y. V. Volkova ◽

K. Y. Sharlai ◽

M. V. Khartanovych

Keyword(s):

Cardiopulmonary Bypass ◽

Hospital Stay ◽

Postoperative Period ◽

Surgical Intervention ◽

Infusion Therapy ◽

The Third ◽

Group I ◽

Aortic Pathology ◽

Number Of Patients ◽

Group Ii

The aim of the work was to analyze the results of the observation of the postoperative period in patients with surgical aortic pathology after surgical intervention using cardiopulmonary bypass. 118 patients with surgical aortic pathology (SAP) were examined. Patients were divided into 2 groups. Group I included 46 patients who were additionally prescribed a solution of meglumin sodium succinate (reamberin), group II included 46 patients who were additionally assigned a solution of D-fructose-1,6-diphosphate sodium hydrate salt (esophosphine). The control group (K) consisted of 26 patients who had surgical pathology of the aorta, all the criteria coincided with patients of groups I and II, but did not have additional substances as part of intensive care (IT) in order to prevent postoperative cognitive dysfunction (PСD). Analyzed the patient's condition on a scale of postoperative mortality prediction EuroSCORE II, the depth of anesthesia with a BIS monitor, the qualitative composition of the leukocyte formula, nasal and rectal temperature, blood gas composition, electrolyte level, glucose, lactate, coagulogram indices, hemolysis and phosphates; levels of autoantibodies to brain antigens (MBP, calcium binding protein S-100, NSE and GBA) were determined in the serum by ELISA a day before the operation and on the first, third, seventh and fourteenth day after surgery. The morphometric and functional properties of erythrocytes were investigated the day before the operation (starting level), 12:00 after the operation, and on the third day of hospital stay. The initial assessment of the cognitive abilities of the patients was made the day before the operation, on the third, seventh and fourteenth day of hospital stay. Used to determine the magnitude of the coefficient of linear Pearson correlation. In the analysis, no significant differences were found between the preliminary data on the phosphorus content in the patients' blood, however, the recovery dynamics of its numbers differed in the K, I and II patients. So, in group K and in group I, after 12:00 after surgery, the level of phosphatemia was 0.86 ± 0.21 mmol/l and 0.85 ± 0.18 mmol / l, on the 3rd day of hospital stay — 0,94 ± 0.08 mmol/l and 0.97 ± 0.04 mmol/l, on the 7th day — 1.04 ± 0.16 mmol/l and 1.07 ± 0.21 mmol/l and on The 14th day — 1.08 ± 0.12 mmol/l and 1.1 ± 0.14 mmol/l. It can be noted that the dynamics of blood phosphatemia in patients of groups K and I was identical, its figures almost coincided in terms of the level of phosphorus in the blood and the corresponding number of patients in the variation rows of patients in both groups. It may be noted that there is an unconditional positive effect on the course of the perioperative period of the option of infusion therapy in the IT complex in patients of group II.

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Comprehensive Treatment of Patients with Constricted Hernias and Metabolic Syndrome Signs

Galician Medical Journal ◽

10.21802/gmj.2016.3.44 ◽

2016 ◽

Vol 23 (3) ◽

Author(s):

I. V. Melnyk

Keyword(s):

Metabolic Syndrome ◽

Postoperative Period ◽

Abdominal Hernia ◽

Wound Complications ◽

Comprehensive Treatment ◽

Clinical Group ◽

Hernia Defect ◽

Group I ◽

Group Ii ◽

Methods Of Treatment

57 patients with constricted abdominal hernia and diagnosed metabolic syndrome were examined. They were performed the urgent hernia defect plastics with polypropylene mesh Linteks-Esfil (St. Petersburg). Patients were divided into two clinical groups: clinical group I (20) included patients in the postoperative period treated with conventional comprehensive conservative treatment. Clinical group II (37) consisted of patients treated with 2.5% solution of 2 ml tiotriazolini in muscle and metformin in a dose of 500 mg / day for metabolic syndrome correction in addition to above mentioned conventional treatment. Lipid metabolism indices improved on the 7th day in 59.2% of patients in clinical group II and only in 15% of patients in clinical group I.Postoperative wound complications such as seromas and infiltrations developed in 6.3% of patients and were eliminated by conservative methods of treatment. Patients of group II tolerated postoperative period better. Average duration of hospital stay decreased by 2.03±0.2 bed days. Thus, the treatment of patients with constricted hernia of anterior abdominal wall and metabolic syndrome should be in complex with hernia defect plastics by propylene mesh and medicamentous correction of metabolism disorders.

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Short term results of percutaneous vertebroplasty in patients with isolated traumatic vertebral compression fractures

Reports of Vinnytsia National Medical University ◽

10.31393/reports-vnmedical-2019-23(3)-11 ◽

2019 ◽

Vol 23 (3) ◽

pp. 401-409

Author(s):

О.S. Voloshchuk ◽

O.P. Krasylenko

Keyword(s):

Motor Activity ◽

Postoperative Period ◽

Percutaneous Vertebroplasty ◽

Age Groups ◽

Vertebral Compression Fractures ◽

Short Term ◽

General Group ◽

Compression Fractures ◽

Group I ◽

Group Ii

Objective — to analyze the effectiveness of percutaneous vertebroplasty (PV) in the short term postoperative period in patients with isolated traumatic vertebral compression fractures (IT VCF). The analysis of short term results of PV for IT VCF in patients (n=160) of two age groups: I — up to 60 years (n=106) and II — 60 years and older (n=54). The criteria for inclusion in the study were: high-energy spinal injury resulting a road accident or a high level fall; absence of signs of osteoporosis. The average pain intensity (M ± σ) before PV matched a severe pain (8.21±1.41 points according VAS in the general group). At 3 days after surgery, the pain radically decreased to insignificant (0.91±0.98 points), gradually decreased to 0.76±0.82 points during the first 3 months; there was a further tendency for its decreasing within the insignificant (up to 0.71±0.76 points after six months). At the same time, before the operation and during the nearest postoperative period, patients of group I had a somewhat lower intensity of pain than in group II. Dependence on painkillers observed in 100% of patients before surgery, in the first 3 days after PV 78.1% of all patients have lost it (80.2% — in group I, 74.0% — in group II); in 3 months — 95,6%, 96,2%, 94,5%, respectively; after 6 months — 96.2%, 97.2%, 94.5%, respectively. Motor activity before surgery was reduced in all patients (45.0% of them to the degree of bedbound). In 3 days after PVP, 60.6% of all patients returned to usual motor activity at home (65.1% in group I, 51.8% in group II), 93.7%, 3 months later, respectively, 2%, 87.0%; in 6 months — 96,3%, 99,1%, 90,7%. The persons of physical work who were employed at the time of injury, remained disabled 3 days after the PVP. Within 3 months, they all returned to work: to their usual work 83.7% in the former group, 90.7% in the first group and 52.9% in the second group; 16,3%, 9,3% and 47,1% of the patients, respectively, for work with facilitated conditions. After 6 months, the number of patients with full physical recovery in these groups reached 94.6%, 97.3% and 82.4%, respectively. Oswestry disability index (ODI), which before the operation was (57.7±20.1)% in the whole group, (55.7±20.85)% — in the first group and (59.6±18.54)% — in group II, and responded to severe disability, 3 days after surgery significantly (p<0.001) decreased and amounted to (31,2±15,89)%, (30,3±16,62)% and (31, 9±14,46)%, respectively, indicating moderate disability. After 3 months, ODI decreased to (18.8±17.45)% (p<0.05) in the general group and to (18.2±18.56)% and (19.1±15.18)% — in the relevant age groups, indicating a minimal disability. After 6 months, there was a tendency for further decrease of ODI (to (18.5±17.1)%) and (17.9±18.08)% and (19.0±15.24)%, respectively). So, in the short term after PV, the degree of disability of patients of both age groups decreased significantly. Thus, PV in patients with IT VCF provides rapid pain regression and improvement in the functional status of patients of both age groups — up to 60 years and 60 years and older. The most radical changes occur within the first 3 days after surgery. Further improvement of most options during the first 6 month is progressing gradually. The rates and completeness of the functional recovery are slightly higher in patients of the age group up to 60 years, compared with the group of 60 years and older.

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Management of patients in the post-operative period after the hip joint replacement accessed by low-invasive access

Physical and rehabilitation medicine, medical rehabilitation ◽

10.36425/2658-6843-2019-4-32-38 ◽

2019 ◽

Vol 1 (4) ◽

pp. 32-38

Author(s):

N S Nikolaev ◽

A V Efimov ◽

R V Petrova ◽

D V Kovalev ◽

M I Ivanov

Keyword(s):

Quality Of Life ◽

Blood Loss ◽

Hip Arthroplasty ◽

Postoperative Period ◽

Early Postoperative Period ◽

Modified Rankin Scale ◽

Surgical Access ◽

Group I ◽

Group Ii

Up to 1.5 million total hip arthroplasty is performed annually in the world. In Russia, at least 300 thousand patients a year need hip replacement surgery. High tissue invasiveness during surgical approaches presents special requirements for the rehabilitation process in the early postoperative period. Accelerating and making it more efficient is possible with the use of the least traumatic operating access. The purpose of the study is a comparative analysis of two models of the organization of rehabilitation in the postoperative period after hip arthroplasty: using standard Harding surgical access and the minimally invasive Rottinger access. Material of the study - patients operated on with standard Harding access (group I, n = 227) and front-external Rottinger access (group II, n = 266). Criteria for inclusion of patients in both groups are primary coxarthrosis without previous surgical interventions, exclusion criteria are connective tissue diseases, severe comorbidity. Group I patients underwent postoperative rehabilitation according to the standard protocol, group II - according to the rehabilitation concept "ERAS, fast-track". To assess the effectiveness of the rehabilitation at all stages in both groups, the rehabilitation potential was assessed on the rehabilitation routing scale (SRM), the dynamics of the pain syndrome on the visual analogue pain scale (VAS), the verticalization period was taken into account, the main assessment scales of the patient's motor functions and psychological status were used in hip arthroplasty: Harris scale, quality of life questionnaire (EQ - 5D), modified Rankin scale. Results and discussion. The proportion of hip arthroplasty using MIS access in the total number of operations increased from 0.7% in 2015 to 10.1% in 2018. The studied groups are comparable in terms of the ratio of men and women, average age, number of observations, BMI and the volume of blood loss. The surgeon duration and the duration of the stationary phase in group I exceeded the similar parameters of the II group. The modified Rankin scale at admission and discharge in all patients showed moderate disability, starting indicators and results after 3 months were more prosperous in group II. Both groups had an equivalent score on the Harris scale before surgery and after 3 months after it, more pronounced positive dynamics of the quality of life on the EQ-5D scale ("thermometer") was noted in group II. A decrease in pain after surgery compared with baseline, with regression to 0.8-1.0 points by 3 months after surgery, was noted in all patients. The assessment on the rehabilitation routing scale did not differ in both groups. At the stationary stage, group I patients walked with additional support on crutches (100%), group II - on a cane (92.5%). On long days 4-6, 82.8% of patients of group I and 91.7% of patients of group II passed long distances. At the end of stage I rehabilitation, 83.7% of group I patients and 92.5% of group II were sent to the outpatient rehabilitation stage, the rest were transferred to stage II of rehabilitation in a 24 - hour hospital. The third stage of rehabilitation, all patients went on an outpatient basis at the place of residence. At the follow-up stage, the data of a telephone survey of group II were analyzed (n = 68, 25.6% of the respondents). By 3 months, the Harris score exceeds 90 points, satisfaction with the operation is 97%. As a result of the use of surgical MIS access for hip arthroplasty, all patients had good rehabilitation indicators. Conclusions. The general approach to managing patients after hip arthroplasty is similar for all types of surgical access, however, MIS-access creates the most favorable conditions for the rehabilitation of patients in the early postoperative period: a positive attitude of the patient, reduced blood loss, reduced surgical incision, the possibility of early activation and transition to the general regime for 6-7 days. The results of the study showed the advantages of a model for the organization of rehabilitation in the postoperative period after hip arthroplasty using mini-invasive access over standard surgical access. Group II patients (MIS access) had a higher level of physical activity and a low level of pain in the early postoperative period.

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Biochemical Blood Parameters and Mineral Metabolism in the Adaptive Period in the Bovine Cattle in the Conditions of the Voronezh Region

International Journal of Biology and Biomedical Engineering ◽

10.46300/91011.2021.15.29 ◽

2021 ◽

Vol 15 ◽

pp. 244-248

Author(s):

A. V. Vostroilov ◽

I. Y. Ventsova ◽

V. A. Safonov

Keyword(s):

Reference Values ◽

Mineral Metabolism ◽

Blood Parameters ◽

Group Iv ◽

Group Iii ◽

Group I ◽

Study Results ◽

Voronezh Region ◽

Group Ii ◽

Adaptation Processes

The study of the process of adaptation of the Belgian breed bovine cattle to the conditions of the Voronezh Region was based on the biochemical blood parameters and mineral metabolism. The experiment included 20 animals divided into four groups (five heads in each group): Group I – covering age heifers, Group II – heifers, Group III – first-calf cows a month after calving, Group IV – one-month-old heifers. In some groups, adaptation processes resulted in deviations from the reference values. In Group II, the level of BUN was 4.7% higher than the norm. In Groups I and IV, the levels of glucose were higher by 7.6% and 38.5%, respectively. In Groups II and III, ALT levels were higher than the norm by 9.1%; in Group I – by 15.7%. In Group II, the level of AST was higher by 5.8% in comparison with the norm. The analysis of mineral metabolism showed that the content of iron was lower than the reference values in first-calf cows in Group III and in heifers in Group IV by 14.4 and 10.8%, respectively. In Group II, the content of copper met the upper border of the reference values. In Group IV, it was elevated by 18.2% in comparison with the norm. The specified deviations indicated the intensification of the metabolic processes during the adaptation of animals to new conditions. The study results showed that the animals of the Belgian breed were capable of adaptation, which provided successful adaptation to new conditions of the Voronezh Region (Russia).

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PLASTICS OF THE ANTERIOR ABDOMINAL WALL IN POSTOPERATIVE VENTRAL HERNIA

Military Medicine ◽

10.51922/2074-5044.2021.2.91 ◽

2021 ◽

pp. 91-97

Author(s):

N. Sivets ◽

◽

D. Kluyko ◽

A. Sivets ◽

D. Holovach ◽

...

Keyword(s):

Surgical Treatment ◽

Plastic Surgery ◽

Abdominal Wall ◽

Ventral Hernia ◽

Postoperative Period ◽

Anterior Abdominal Wall ◽

Treatment Efficiency ◽

Ventral Hernias

Objective. Improving the postoperative ventral hernias surgical treatment efficiency. Authors of the article define the clinically developed method of plastic surgery of the anterior abdominal wall in postoperative ventral hernia. Operations with this technique were performed in 37 patients. The endoprosthesis used was a polypropylene net made by “Eticon”. In the postoperative period complications took place in 2 (5,4%) patients. Conclusion. The developed method of the anterior abdominal wall plastics effectiveness was established in the article.

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Protective effect of blackthorn fruits (Prunus spinosa) against tartrazine toxicity development in albino Wistar rats

10.31219/osf.io/mdshk ◽

2019 ◽

Author(s):

Igori Balta ◽

Bogdan Sevastre ◽

Vioara Mireșan ◽

Marian Taulescu ◽

Camelia Raducu ◽

...

Keyword(s):

Wistar Rats ◽

Hematological Parameters ◽

Blood Parameters ◽

Control Group ◽

Water Mixture ◽

Water Group ◽

Prunus Spinosa ◽

Food Dye ◽

Group I ◽

Group Ii

Background: Tartrazine (Yellow 5 or E102) is a synthetic food dye able to modify perception and behavior, causingagitation, confusion, rhinitis and can produce hyperactivity syndrome in children when is combined with benzoates.Additionally, it can trigger oxidative stress which consequently generates metabolic disorders. Therefore, the studywas designed to evaluate the harmful effects of the food additive tartrazine and to observe beneficial properties ofblackthorn fruits (Prunus spinosa) on the blood and organs of albino Wistar rats.Materials and methods: This study was carried out on 20 mature Wistar rats, randomly divided into four groupsof five animals. Over the course of the experiment, the control group received only food and drinking water, group Ireceived 75 mg of tartrazine dissolved in (250 ml) water group II was given 75 mg of tartrazine and 200 mg of driedblackthorn fruit powder 200 mg dissolved simultaneously in (250 ml) of tartrazine-water mixture (aiming to reducethe tartrazine toxicity) and group III received a higher dose of tartrazine (100 mg) in (250 ml) of water.Results: At the end of the experiment, values regarding kidney and liver weight were significantly increased, whilethe weight of the spleen was slightly decreased compared with the weight of the control group. Biochemical andhematological assays, of the blood samples show that the addition of tartrazine in the diet of rats caused significantchanges in all biochemical and hematological parameters of the blood. In the group II, which received (P. spinosa)powder combined with tartrazine, the biochemical and hematological parameters had average values similar to thecontrol group.Conclusions: Histopathological assay showed that the application of tartrazine in the group I, II and III producedlesions of the kidneys, spleen and the liver for all rodents. Tartrazine was able to generate histopathological changes,which caused significantly tissue lesions of the liver and significant changes in blood parameters. Blackthorn powdershowed a promising protective role for the blood parameters but demonstrated no significant benefits for the organs.

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CHANGE IN THE QUALITY OF LIFE OF CHILDREN AFTER SURGICAL TREATMENT OF RETINAL DETACHMENT

Kuban Scientific Medical Bulletin ◽

10.25207/1608-6228-2018-25-6-149-153 ◽

2018 ◽

Vol 25 (6) ◽

pp. 149-153

Author(s):

A. N. Sergienko ◽

V. V. Dashina ◽

A. V. Malyshev ◽

O. I. Lysenko ◽

S. V. Yanchenko

Keyword(s):

Quality Of Life ◽

Statistical Analysis ◽

Surgical Treatment ◽

Retinal Detachment ◽

Postoperative Period ◽

Control Group ◽

Russian Version ◽

Group I ◽

Group Ii

Aim.The study was designed for the evaluation of the quality of life of children with retinal detachment during vitrectomy.Materials and methods. 23 children with retinal detachment aged from 10 to 17 years were treated. Surgical treatment consisted of a three-port vitrectomy and a laser endocoagulation of the retina. 3 groups were formed with the help of a random sampling. During the surgical treatment of group I (n=8), only balanced non-oxidant solutions of salts (Balsed Salt Solution − BSS) were used. Tablets of antioxidant preparations were not assigned. Saline solutions with antioxidants (BSS plus) were used to carry out surgery for group II (n=8). Group III (n=7) was additionally taking antioxidant preparations peros for 3 months in the postoperative period . The quality of life was studied using the abridged Russian version of the VFQ-25 questionnaire. 10 children of the same age with no indications of surgical treatment of retinal detachment were selected for the control group. Statistical analysis of the obtained data was carried out using a set of programs for applied statistical analysis Analyst Soft, Bio Stat 2007.Results.A week after the surgical treatment, no increase in visometric data was observed. Six months later, a significant increase in visual acuity was revealed. The highest visometric data were observed in group II due to the minimal progression of lens opacities. Group I patients had the lowest values of this index.Conclusion.The positive effect of the surgical treatment of retinal detachment positively influenced the patients’ quality of life in the early and late postoperative period.

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Ticlopidin In The Prevention Of Platelet Hyperaggregation In Surgery

10.1055/s-0038-1653257 ◽

1981 ◽

Author(s):

M L Scrobohaci ◽

T Petrilắ ◽

D Mihắitắ ◽

M Alexapdrescu ◽

I Pop ◽

...

Keyword(s):

Platelet Aggregation ◽

Platelet Function ◽

Postoperative Period ◽

Congenital Heart ◽

Coronary Bypass ◽

Preoperative Period ◽

Heart Patients ◽

Group I ◽

Group Ii ◽

Platelet Hyperaggregation

The effects of ticlopidin on platelet function was estimated in two groups of patients: group I: 9 patients with thrombocytosis (6 chronic granulocytic leukaemia patients, 3 idiopathic thrombocytopenic purpura patients); group II: 18 patients undergoing extracorporeal circulation (ECC)-(4 aorto-coronary bypass patients, 9 valvular patients and 5 congenital heart patients). Platelet function was assessed by the following tests: platelet aggregation (Born ’ s technique) with ADP and collagen; index of aggregated platelets (Wu and Hoak’s technique). The treatment with ticlopidin was administrated: in group I (24-48h), in the postoperative period, when platelets were ≃500,000/mm3; in group II (24-48h), for the preoperative period (750 mg. daily).The index of aggregated platelets normalized in group I - from 0.2 to 0.8 and in group II - from 0.4 to 0.8. The extent of platelet aggregation decreased in group I - from 80% to 20% and in Group II - from 50% to 20% at the beginning of anaesthesia before ECC.We did not observe any haemorrhagic accident in the postoperative period in either group.

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Simultaneous abdominoplasty and laparoscopic ventral hernia alloplasty in patients with obesity

Acta Medica Leopoliensia ◽

10.25040/aml2020.04.045 ◽

2020 ◽

Vol 26 (4) ◽

pp. 45-49

Author(s):

V.V. Boiko ◽

◽

K.Yu. Parkhomenko ◽

◽

...

Keyword(s):

Ventral Hernia ◽

Postoperative Period ◽

Average Length ◽

Lower Lobe ◽

Long Term Results ◽

Hospital Treatment ◽

Surgical Interventions ◽

Cosmetic Results ◽

Good Cosmetic ◽

Ventral Hernias

Aim. To study the results of simultaneous abdominoplasty and laparoscopic ventral hernia alloplasty in patients with obesity. Material and Methods. Simultaneous adbominoplasty and laparoscopic hernioplasty for ventral hernias were performed in 31 patients. The mean age of the patients was 53.7±6.5 (95% CI 51.3; 56.0). All patients were diagnosed as obese (body mass index more than 30 kg/m2). Incisional hernia was the main indication for surgery in the majority of patients - 20 (64,5%); in 11 (35%) cases a primary hernia of median localization was detected. Immediate and long-term results of surgical interventions were studied. Results and Discussion. In the postoperative period after drainage removal accumulations of fluid (seromas) were revealed in 9 (29%) patients using ultrasound investigation; in 2 cases they were evacuated by puncture. In one case, a marginal necrosis of the skin around the formed umbilicus occurred (healing by secondary tension); in another, lower lobe pneumonia was diagnosed (eliminated by antibiotic therapy). The average length of hospital stay was 7.3±1.4 (95% CI 6.8; 7.9) days, 6-8 days in most cases. Only two patients were hospitalized for more than 8 days due to postoperative complications. No recurrences of hernias were registered at follow-up examination 1-3 years later; good cosmetic results were achieved. Conclusions. In patients with ventral hernias with obesity and fat apron it is advisable to perform simultaneous intervention - abdominoplasty and allogernioplasty. It is advisable to perform alloplasty of ventral hernias with simultaneous abdominoplasty via laparoscopic access according to IPOM technology with the use of mesh endoprosthesis with antiadhesive coating. Simultaneous abdominoplasty causes an increase in the frequency of seromas in the postoperative period, but it does not increase the duration of hospital treatment. Simultaneous surgeries allow achieving good cosmetic results and do not increase the incidence of hernia recurrence. Keywords: obesity, fat apron, ventral hernia, abdominoplasty, laparoscopic alogernioplasty, result

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