scholarly journals Human Pelvis and Long Bones Reveal Differential Preservation of Ancient Population History and Migration Out of Africa

Human Biology ◽  
2012 ◽  
Vol 84 (2) ◽  
pp. 139-152 ◽  
Author(s):  
Lia Betti ◽  
Noreen Von Cramon-Taubadel ◽  
Stephen J. Lycett
Keyword(s):  
Population History ◽  
Long Bones ◽  
Ancient Population ◽  
Out Of Africa ◽  
And Migration

scholarly journals Features of choosing the tactics and method of treatment of external joint frequencies of long external bones in people living with HIV

2020 ◽  
Vol 12 (1) ◽  
pp. 65-72
Author(s):  
N. G. Doronin ◽  
S. N. Khoroshkov ◽  
S. L. Maksimov
Keyword(s):  
Hiv Infection ◽  
Infectious Complications ◽  
Antiretroviral Drugs ◽  
People Living With Hiv ◽  
Long Bones ◽  
Treatment Results ◽  
Improve Treatment ◽  
Articular Fractures ◽  
And Migration ◽  
Living With Hiv

Objective. Develop an algorithm for determining tactics and parameters of their treatment to improve treatment outcomes. Methodology. Material and research methods. A statistical analysis of the treatment results of 90 HIV-infected patients aged from 23 to 54 years with extra-articular fractures of long bones of the extremities was carried out. When determining the tactics and method of treatment, the peculiarities of the effect of HIV infection, antiretroviral drugs, and opportunistic diseases on the patient’s body were not taken into account. Results. Non-infectious complications are characteristic of HIV-infected patients: sides of the postoperative wound (seromas, hematomas, discrepancy of wound edges, delayed crushing), aseptic loosening and migration of fixatives, delayed consolidation of fractures. The presence of a statistically significant relationship between the objective factors characterizing the course of HIV infection: the stage of the disease, the number of CD lymphocytes, the ratio of CD4 / CD8 lymphocytes, viral load and the risk of postoperative complications was revealed.Conclusion. The application of the developed algorithm allows you to objectify the procedure and provide an individual approach in determining the tactics and method of treatment for HIV-infected patients with extraarticular fractures of long bones of the extremities

Large and ancient linguistic areas

2020 ◽  
pp. 78-100
Author(s):  
Balthasar Bickel
Keyword(s):  
Regression Models ◽  
Large Scale ◽  
Population History ◽  
False Discovery Rates ◽  
Ancient Population ◽  
False Discovery ◽  
Language Universals ◽  
Discovery Rates ◽  
Pacific Area

Large-scale areal patterns point to ancient population history and form a well-known confound for language universals. Despite their importance, demonstrating such patterns remains a challenge. This chapter argues that large-scale area hypotheses are better tested by modeling diachronic family biases than by controlling for genealogical relations in regression models. A case study of the Trans-Pacific area reveals that diachronic bias estimates do not depend much on the amount of phylogenetic information that is used when inferring them. After controlling for false discovery rates, about 39 variables in WALS and AUTOTYP show diachronic biases that differ significantly inside vs. outside the Trans-Pacific area. Nearly three times as many biases hold outside than inside the Trans-Pacific area, indicating that the Trans-Pacific area is not so much characterized by the spread of biases but rather by the retention of earlier diversity, in line with earlier suggestions in the literature.

Population

2020 ◽  
pp. 258-276
Author(s):  
Tirthankar Roy
Keyword(s):  
Population Growth ◽  
Demographic Change ◽  
Demographic Transition ◽  
Turning Point ◽  
Population History ◽  
World Population ◽  
Initial Size ◽  
Slow Pace ◽  
And Migration ◽  
Population Demographic

India’s population, long-stagnant or growing only at a slow pace, began to grow rapidly from the 1920s. Given the large initial size of the population, demographic change in this region was a turning point in world population history. What had changed to produce this turn? Chapter 10 considers the demographic transition with attention paid to population growth, famines, epidemics, and migration.

Climate, Crops, and Natural Increase in Rural Russia, 1861–1913

Slavic Review ◽  
1986 ◽  
Vol 45 (3) ◽  
pp. 457-469 ◽  
Author(s):  
Mary Kilbourne Matossian
Keyword(s):  
Mortality Rate ◽  
Infant Mortality ◽  
Natural Increase ◽  
Population History ◽  
European Russia ◽  
Infant Mortality Rate ◽  
Russian People ◽  
History Of ◽  
And Migration ◽  
People Today

A great many available statistics describe the population history of Russia, but explanations for these statistics are limited or nonexistent. The useful studies of fertility and migration that have appeared are primarily accurate reports of what happened. Studies of Russian mortality are wholly lacking, an understandable situation, since as late as 1913 only thirteen out of fifty provinces of European Russia had medical statistical bureaus. Despite all past efforts the history of Russia's health remains obscure.While the health of the Russian people today is comparable to that of other Europeans, before the Revolution of 1917 it was extremely poor. In 1897, the year of the first national Russian census, the infant mortality rate for European Russia was 260 for each 1,000 births, compared to 222 for Germany, 164 for France, 156 for Italy, 156 for England and Wales, and 109 for Ireland.

scholarly journals Ancient ancestry informative markers for identifying fine-scale ancient population structure in Eurasians

2018 ◽  
Author(s):  
Umberto Esposito ◽  
Ranajit Das ◽  
Mehdi Pirooznia ◽  
Eran Elhaik
Keyword(s):  
Population Structure ◽  
Ancient Dna ◽  
Principal Component ◽  
Population History ◽  
Fine Scale ◽  
Ancestry Informative Markers ◽  
Ancient Population ◽  
Human Genomes ◽  
Rapid Accumulation ◽  
Time Periods

AbstractThe rapid accumulation of ancient human genomes from various areas and time periods potentially allows the expansion of studies of biodiversity, biogeography, forensics, population history, and epidemiology into past populations. However, most ancient DNA (aDNA) data were generated through microarrays designed for modern-day populations known to misrepresent the population structure. Past studies addressed these problems using ancestry informative markers (AIMs). However, it is unclear whether AIMs derived from contemporary human genomes can capture ancient population structure and whether AIM finding methods are applicable to ancient DNA (aDNA) provided that the high missingness rates in ancient, oftentimes haploid, DNA can also distort the population structure. Here, we define ancient AIMs (aAIMs) and develop a framework to evaluate established and novel AIM-finding methods in identifying the most informative markers. We show that aAIMs identified by a novel principal component analysis (PCA)-based method outperforms all competing methods in classifying ancient individuals into populations and identifying admixed individuals. In some cases, predictions made using the aAIMs were more accurate than those made with a complete marker set. We discuss the features of the ancient Eurasian population structure and strategies to identify aAIMs. This work informs the design of population microarrays and the interpretation of aDNA results.

scholarly journals Out of Africa by spontaneous migration waves

2018 ◽  
Author(s):  
Paul D. Bons ◽  
Catherine C. Bauer ◽  
Hervé Bocherens ◽  
Tamara de Riese ◽  
Dorothée G. Drucker ◽  
...  
Keyword(s):  
Assortative Mating ◽  
Current Model ◽  
Source Region ◽  
Regional Differentiation ◽  
Power Law Distribution ◽  
Modern Humans ◽  
Large Wave ◽  
Anatomically Modern Humans ◽  
Out Of Africa ◽  
And Migration

AbstractHominin evolution is characterized by progressive regional differentiation, as well as migration waves, leading to anatomically modern humans that are assumed to have emerged in Africa and spread over the whole world. Why or whether Africa was the source region of modern humans and what caused their spread remains subject of ongoing debate. We present a spatially explicit, stochastic numerical model that includes ongoing mutations, demic diffusion, assortative mating and migration waves. Diffusion and assortative mating alone result in a structured population with relatively homogeneous regions bound by sharp clines. The addition of migration waves results in a power-law distribution of wave areas: for every large wave, many more small waves are expected to occur. This suggests that one or more out-of-Africa migrations would probably have been accompanied by numerous smaller migration waves across the world. The migration waves are considered “spontaneous”, as the current model excludes environmental or other factors. Large waves preferentially emanate from the central areas of large, compact inhabited areas. During the Pleistocene, Africa was the largest such area most of the time, making Africa the statistically most likely origin of anatomically modern humans, without a need to invoke additional environmental or ecological drivers.

Patterns and Management of Fractures of Long Bones: A Study of the Ancient Population of Saqqara, Egypt

2013 ◽  
Vol 89 ◽  
pp. 133-156
Author(s):  
Iwona Kozieradzka-Ogunmakin
Keyword(s):  
Medical Treatment ◽  
Upper Limb ◽  
Age Groups ◽  
The State ◽  
Long Bones ◽  
Male And Female ◽  
Ancient Population ◽  
Old Kingdom ◽  
Old Adults ◽  
Location Type

A skeletal collection from 105 burials excavated at the Old Kingdom and Ptolemaic Period cemetery in Saqqara, Egypt, was investigated for evidence of ante-mortem fractures of long bones. The collection comprised 57 males, 30 females, 14 unsexed sub-adults, and 4 unsexed mature individuals. The majority of the skeletons were complete or almost complete, despite the disturbance caused by tomb looters in antiquity. Fractures were recorded by bone, side, location, type and state of healing. The prevalence of fractures was calculated in male and female populations, as well as in individual age groups. The state of healing of the fractures was examined in order to investigate the possibility of medical treatment provided. No evidence of fractures was recorded in subadults. Evidence of single fractures were found in fourteen adults, and a further five individuals sustained two fractures to different bones of the upper limb. The frequency of fractures by bone count was the highest among the Middle and Old Adults. Fractures to the radius (37.5%) and the ulna (33.3%) were the most common, while no fractures were recorded in the tibia. Angulation, rotation and shortening were observed among the healed bones.

scholarly journals The impact of recent population history on the deleterious mutation load in humans and close evolutionary relatives

2016 ◽  
Author(s):  
Yuval B. Simons ◽  
Guy Sella
Keyword(s):  
Demographic History ◽  
Population History ◽  
Human Populations ◽  
Data Sets ◽  
Loss Of Function ◽  
Mutation Load ◽  
Synonymous Mutations ◽  
Show Evidence ◽  
Out Of Africa ◽  
The Impact

AbstractOver the past decade, there has been both great interest and confusion about whether recent demographic events—notably the Out-of-Africa-bottleneck and recent population growth—have led to differences in mutation load among human populations. The confusion can be traced to the use of different summary statistics to measure load, which lead to apparently conflicting results. We argue, however, that when statistics more directly related to load are used, the results of different studies and data sets consistently reveal little or no difference in the load of non-synonymous mutations among human populations. Theory helps to understand why no such differences are seen, as well as to predict in what settings they are to be expected. In particular, as predicted by modeling, there is evidence for changes in the load of recessive loss of function mutations in founder and inbred human populations. Also as predicted, eastern subspecies of gorilla, Neanderthals and Denisovans, who are thought to have undergone reductions in population sizes that exceed the human Out-of-Africa bottleneck in duration and severity, show evidence for increased load of non-synonymous mutations (relative to western subspecies of gorillas and modern humans, respectively). A coherent picture is thus starting to emerge about the effects of demographic history on the mutation load in populations of humans and close evolutionary relatives.

Introduction

2018 ◽  
Author(s):  
Terence Keel
Keyword(s):  
Human Evolution ◽  
Human Life ◽  
Critical Evaluation ◽  
Epistemic Authority ◽  
Theoretical Ground ◽  
Human Origins ◽  
Out Of Africa ◽  
And Migration ◽  
Single Set

The Introduction lays out the theoretical stakes of the work as a whole. It opens with a critical evaluation of the work of acclaimed geneticist Spencer Wells, whose 2002 publication The Journey of Man has helped frame the now-standard interpretation of human evolution and migration from a single set of ancestors out of Africa. Wells’s account of human evolution reveals the epistemic authority that modern genetics has obtained on the question of race and human beginnings. It is argued that contemporary biologists inherited this authority, however, from their Christian intellectual ancestors, who provided modern scientists with a cache of interpretive tools and assumptions that proved useful for narrating the development of human life and constructing theories of racial difference believed to supersede all previous accounts of human origins. After laying out the theoretical ground to be covered, this introductory chapter provides an overview of the chapters that follow.

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