scholarly journals Case Report: Miles Surgery Ameliorates High Blood Pressure in a Rectal Carcinoma Patient With Essential Hypertension

2021 ◽  
Vol 8 ◽  
Author(s):  
Meng-Wan Zhang ◽  
Bo-Shi Fan ◽  
Jian-Guang Yu
Keyword(s):  
Blood Pressure ◽  
Rectal Carcinoma ◽  
Pressure Control ◽  
The Novel ◽  
Factors Affecting ◽  
Multiple Factors ◽  
Tract Function ◽  
History Of ◽  
Novel Strategy ◽  
Underlying Mechanisms

Hypertension is one of the major causes of public health problems. Multiple factors affecting gastrointestinal tract function are involved in hypertension. Emerging studies have manifested that gut intervention may play significant roles in regulating blood pressure but the underlying mechanisms are complex and not fully clear. Here, we report a case of 66 years old male who had a long history of hypertension and received Miles surgery for rectal carcinoma. The blood pressure of this patient was returned to normal levels after the operation. The possible reasons could be the modulation of sympathetic tone and the gut microbiota-brain axis. This report provides evidence about the relevance between hypertension and gut intervention particularly in the colorectal sites and gives hints for investigating the possible mechanisms of hypertension and the novel strategy for blood pressure control.

A Randomised Trial of Intensive versus Standard Blood-Pressure Control in Patients with a History of Stroke: The RESPECT Study

2018 ◽  
Author(s):  
Kazuo Kitagawa ◽  
Yasumasa Yamamoto ◽  
Hisatomi Arima ◽  
Toshiki Maeda ◽  
Norio Sunami ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Blood Pressure Control ◽  
Randomised Trial ◽  
Pressure Control ◽  
History Of

scholarly journals Effects of eplerenone on resistance to antihypertensive medication in patients with primary or secondary hyperaldosteronism

2017 ◽  
Vol 5 (2) ◽  
pp. 93-99 ◽  
Author(s):  
J. David Spence ◽  
Chrysi Bogiatzi ◽  
Mariya Kuk ◽  
George K. Dresser ◽  
Daniel G. Hackam
Keyword(s):  
Blood Pressure ◽  
Resistant Hypertension ◽  
Concomitant Medication ◽  
Antihypertensive Medication ◽  
Pressure Control ◽  
Blinded Study ◽  
History Of ◽  
Secondary Hyperaldosteronism ◽  
One Year ◽  
Resistance Score

Abstract Background and Objectives Resistant hypertension is an important problem; nearly half of diagnosed hypertensives are not controlled to target blood pressure levels, and approximately 90% of strokes occur among patients with resistant hypertension. Primary aldosteronism accounts for approximately 20% of resistant hypertension, but the role of secondary hyperaldosteronism in resistant hypertension is seldom considered. We assessed the effects of eplerenone in patients with hypertension and either primary or secondary hyperaldosteronism. Methods Patients with a history of resistant hypertension and a supine plasma aldosterone level ≥ 360 pmol/L were randomized to eplerenone versus placebo in a fully blinded study for one year. A medication intensity score was developed to assess the resistance of hypertension to medication (blood pressure × medication intensity). We assessed the effects of eplerenone on blood pressure and on resistance to concomitant medication. Results Final results were available in 37 patients (19 on eplerenone and 18 on placebo). Resistance to medication, as assessed by the intensity of concomitant medication required to maintain blood pressure control, was markedly reduced by eplerenone: medication intensity scores declined by –0.50 ± 1.04 (SD) on placebo versus –2.11 ± 1.45 with eplerenone (P = 0.0001), the Systolic Resistance Score declined by –80.00 ± 122.93 on placebo versus –334.05 ± 21.73 on eplerenone (P = 0.0001), and the Diastolic Resistance Score increased by 1.28 ± 31.65 on placebo and declined by –40.74 ± 57.08 on eplerenone (P = 0.009). Conclusions Eplerenone significantly reduced resistance to concomitant antihypertensive medication in both primary and secondary hyperaldosteronism.

Abstract TMP56: Prediction of Primary Stroke: A Secondary Analysis of the SPRINT Trial

Stroke ◽  
2020 ◽  
Vol 51 (Suppl_1) ◽  
Author(s):  
Adam H de Havenon ◽  
Eric Goldstein ◽  
Stephanie Lyden ◽  
Jennifer Majersik
Keyword(s):  
Blood Pressure ◽  
Ischemic Stroke ◽  
Blood Pressure Control ◽  
Primary Outcome ◽  
Disease Risk ◽  
Cardiovascular Disease Risk ◽  
Blood Pressure Reduction ◽  
Pressure Control ◽  
Significant Difference ◽  
History Of

Background: The Systolic Blood Pressure Intervention Trial enrolled patients aged 50 or older with at least one cardiovascular disease risk factor, but free of prior symptomatic stroke. Patients were assigned to two blood pressure reduction goals (<140 versus 120 mm Hg). There was not a significant difference in the rate of stroke, making this an ideal cohort to refine risk prediction of primary stroke, which is understudied in patients with adequate blood pressure control and a rigorously adjudicated outcome of stroke. Methods: The primary outcome is ischemic stroke. We fit Cox models to the primary outcome and evaluated all baseline demographic variables to determine which would be most predictive of stroke, which we then used to create a prediction score. Results: We included 9,361 patients with a mean (SD) age of 67.9 (9.4) years and 171 (1.8%) patients met the primary outcome of stroke. For our prediction model, we gave one point each for history of TIA, atrial fibrillation, congestive heart failure, or diabetes. Patients with 2 or more points were collapsed, making three possible scores of 0, 1, and 2, which had rates of stroke of 1.5% (117/8042), 3.2% (30/933), and 6.2% (24/386) (p<0.001). Compared to a score of 0, the hazard ratios for stroke of score 1 and 2 were 2.3 (95% CI, 1.6-3.5) and 4.6 (95% CI, 2.9-7.1) (both p<0.001) (Figure 1). Conclusion: A simple scoring system can improve prediction of ischemic stroke from 1.8% to 6.2% in patients with no prior history of stroke and excellent blood pressure control. This information could be used to improve patient selection for clinical trials or for identifying patients for more aggressive primary prevention strategies.

Blood Pressure Control in Hypertensive Patients With a History of Stroke

2005 ◽  
Vol 14 (6) ◽  
pp. 229-233 ◽  
Author(s):  
Yuko Ohta ◽  
Takuya Tsuchihashi ◽  
Setsuro Ibayashi ◽  
Kiyoshi Matsumura ◽  
Takanari Kitazono ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Blood Pressure Control ◽  
Pressure Control ◽  
Hypertensive Patients ◽  
History Of

Factors associated with poor tensional control in the elderly

2021 ◽  
Vol 28 (Supplement_1) ◽  
Author(s):  
Z Bargaoui ◽  
K Mzoughi ◽  
S Labbene ◽  
I Zairi ◽  
S Kraiem ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Risk Factor ◽  
Cardiovascular Risk ◽  
Blood Pressure Control ◽  
The Elderly ◽  
Pressure Control ◽  
Thiazide Diuretics ◽  
Factors Associated ◽  
Poor Blood Pressure Control ◽  
History Of

Abstract Funding Acknowledgements Type of funding sources: None. Background Hypertension is a major cardiovascular risk factor, responsible for significant morbidity and mortality. Despite therapeutic progress, blood pressure control remains insufficient. Purpose The aim of our study was to identify the factors associated with poor blood pressure control in the elderly. Methods This was a descriptive study with a prospective data collection including 101 hypertensive treated subjects, aged 65 years and over, followed on outpatient basis between November and December 2019 at the cardiology consultation either at the Habib Thameur hospital or at the Materi hospital. Results Median age was 73 and sex ratio 0.57. The major cardiovascular risk factor was diabetes in 60.4% of cases, followed by dyslipidaemia 48.5% and smoking 40.6%. A history of coronary syndrome was present in 36.6% of cases, followed by atrial fibrillation in 19.8% and 12.9% had a history of ischemic stroke. Thirty-three percent realized regular physical activity and 31% had a high-sodium diet. Four percent of our patients were completely dependent. Among our patients aged 80 and over, 68.2% were frail. The prevalence of poor blood pressure control was 59%. Adherence to treatment was satisfactory in 75.2% of cases. Twelve percent of patients had information about their condition and 89% knew the dosage and schedule for their medication. In multivariate analysis, the factors associated with poor blood pressure control were: non-compliance with treatment (adjusted OR = 0.19; p = 0.013), frailty (adjusted OR = 7.194; p = 0.004), the number of antihypertensive tablets (Adjusted OR = 0.382; p = 0.008), non-use of thiazide diuretics (adjusted OR = 25.903; p = 0.001) and the patient"s lack of knowledge of antihypertensive treatment (adjusted OR = 0.56; p = 0.008). Conclusion Detection of the risk of non-compliance, the use of thiazide diuretics, reducing the number of antihypertensive tablets, screening for frailty and informing the patient about his treatment are necessary to improve blood pressure control in the elderly.

scholarly journals Faktor Risiko yang Mempengaruhi Terjadinya Stroke Non Hemoragik pada Pasien di RS RK Charitas dan RS Myria Palembang

2020 ◽  
Vol 9 (2) ◽  
pp. 268
Author(s):  
Bangun Dwi Hardika ◽  
M Yuwono ◽  
HM Zulkarnain
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Multivariate Analysis ◽  
Hemorrhagic Stroke ◽  
Case Control ◽  
Blood Cholesterol ◽  
Total Blood ◽  
Factors Affecting ◽  
History Of ◽  
Total Blood Cholesterol

Non-hemorrhagic stroke is a frequent case of stroke caused by blockage of blood vessels and the accumulation of changeable and unchangeable risk factors. The impact of stroke is a long-term physical and functional disorder that affects the life quality of the patient and the family. The aim of this study was to analyze the factors that influence the occurrence of non-hemorrhagic stroke. This study is an observational analytic epidemiological study with case control research design conducted in 2 private hospitals. The samples were selected sequentially with a ratio of 1: 2 (case: control) consisting of 50 patients with non-hemorrhagic stroke and 100 patients without non-hemorrhagic stroke. The data was analyzed by univariate, bivariate, and multivariate analysis method by using binary logistic regression. The results of risk factor analysis which were independently associated were Total Blood Cholesterol, History of Hypertension, Systolic Blood Pressure, Diastolic Blood Pressure, and Cardiac Examination. The multivariate analysis showed that the risk factors affecting non hemorrhagic stroke were History of Hypertension (OR: 6,476, p = 0.000, 95% CI: 2,338-17,935), Total Blood Cholesterol Level ≥200 mg/dl (OR: 6,139, p = 0.000, 95% CI: 2,334-16,148), Education Level (OR: 0,311, p = 0.009, 95% CI: 0,129-0,747), Gender (OR: 0.379, p = 0.022, 95% CI: 0.165-0.871 ), and Obesity (OR: 2,217, p = 0.080, 95% CI: 0.910-5.401). As a conclusion, there were 5 variables of risk factors that influence to Non Hemorrhagic Stroke. If those variables of risk factors were exist in the respondent, the risk of a non hemorrhagic Stroke reached 81.6%. It was suggested that the patients made an effort on preventions by maintaining a healthy lifestyle and controlling risk factors affecting the occurrence of non-hemorrhagic stroke.

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