scholarly journals A Systematic Scoping Review of New Attention Problems Following Traumatic Brain Injury in Children

2021 ◽  
Vol 12 ◽  
Author(s):  
Sonja Stojanovski ◽  
Shannon E. Scratch ◽  
Benjamin T. Dunkley ◽  
Russell Schachar ◽  
Anne L. Wheeler
Keyword(s):  
Risk Factors ◽  
Brain Injury ◽  
Scoping Review ◽  
Brain Injuries ◽  
Attention Problems ◽  
Future Research ◽  
Original Research ◽  
Neural Basis ◽  
Adhd Diagnosis ◽  
Wide Range

Objective: To summarize existing knowledge about the characteristics of attention problems secondary to traumatic brain injuries (TBI) of all severities in children.Methods: Computerized databases PubMed and PsychINFO and gray literature sources were used to identify relevant studies. Search terms were selected to identify original research examining new ADHD diagnosis or attention problems after TBI in children. Studies were included if they investigated any severity of TBI, assessed attention or ADHD after brain injury, investigated children as a primary or sub-analysis, and controlled for or excluded participants with preinjury ADHD or attention problems.Results: Thirty-nine studies were included in the review. Studies examined the prevalence of and risk factors for new attention problems and ADHD following TBI in children as well as behavioral and neuropsychological factors associated with these attention problems. Studies report a wide range of prevalence rates of new ADHD diagnosis or attention problems after TBI. Evidence indicates that more severe injury, injury in early childhood, or preinjury adaptive functioning problems, increases the risk for new ADHD and attention problems after TBI and both sexes appear to be equally vulnerable. Further, literature suggests that cases of new ADHD often co-occurs with neuropsychiatric impairment in other domains. Identified gaps in our understanding of new attention problems and ADHD include if mild TBI, the most common type of injury, increases risk and what brain abnormalities are associated with the emergence of these problems.Conclusion: This scoping review describes existing studies of new attention problems and ADHD following TBI in children and highlights important risk factors and comorbidities. Important future research directions are identified that will inform the extent of this outcome across TBI severities, its neural basis and points of intervention to minimize its impact.

scholarly journals Temporal patterns of microglial activation in white matter following experimental mild traumatic brain injury: a systematic literature review

2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Prashanth S. Velayudhan ◽  
Nicole Schwab ◽  
Lili-Naz Hazrati ◽  
Anne L. Wheeler
Keyword(s):  
Brain Injury ◽  
White Matter ◽  
Microglial Activation ◽  
Brain Injuries ◽  
Experimental Studies ◽  
Current Understanding ◽  
Future Research ◽  
Cell Integrity ◽  
Experimental Conditions ◽  
Wide Range

AbstractMild traumatic brain injuries (mTBIs) are a prevalent form of injury that can result in persistent neurological impairments. Microglial activation has become increasingly recognized as a key process regulating the pathology of white matter in a wide range of brain injury and disease contexts. As white matter damage is known to be a major contributor to the impairments that follow mTBI, microglia have rightfully become a common target of investigation for the development of mTBI therapies and biomarkers. Recent work has demonstrated that the efficacy of microglial manipulation as a therapeutic intervention following injury or disease is highly time-sensitive, emphasizing the importance of advancing our understanding of the dynamics of post-mTBI microglial activation from onset to resolution. Current reporting of microglial activation in experimental studies of mTBI is non-standardized, which has limited our ability to identify concrete patterns of post-mTBI microglial activation over time. In this review, we examine preclinical studies of mTBI that report on microglial activation in white matter regions to summarize our current understanding of these patterns. Specifically, we summarize timecourses of post-mTBI microglial activation in white matter regions of the brain, identify factors that influence this activation, examine the temporal relationship between microglial activation and other post-mTBI assessments, and compare the relative sensitivities of various methods for detecting microglial activation. While the lack of replicated experimental conditions has limited the extent of conclusions that can confidently be drawn, we find that microglia are activated over a wide range of timecourses following mTBI and that microglial activation is a long-lasting outcome of mTBI that may resolve after most typical post-mTBI assessments, with the exception of those measuring oligodendrocyte lineage cell integrity. We identify several understudied parameters of post-mTBI microglial activation in white matter, such as the inclusion of female subjects. This review summarizes our current understanding of the progression of microglial activation in white matter structures following experimental mTBI and offers suggestions for important future research directions.

scholarly journals Applied sport science and medicine of women’s rugby codes: a systematic-scoping review and consensus on future research priorities protocol

2021 ◽  
Vol 7 (3) ◽  
pp. e001108
Author(s):  
Omar Heyward ◽  
Stacey Emmonds ◽  
Gregory Roe ◽  
Sean Scantlebury ◽  
Keith Stokes ◽  
...  
Keyword(s):  
Scoping Review ◽  
Research Priorities ◽  
Consensus Method ◽  
Future Research ◽  
Delphi Consensus ◽  
Medicine Research ◽  
Sport Science ◽  
Priority Areas ◽  
Wide Range ◽  
Scoping Reviews

Women’s rugby (rugby league, rugby union and rugby sevens) has recently grown in participation and professionalisation. There is under-representation of women-only cohorts within applied sport science and medicine research and within the women’s rugby evidence base. The aims of this article are: Part 1: to undertake a systematic-scoping review of the applied sport science and medicine of women’s rugby, and Part 2: to develop a consensus statement on future research priorities. This article will be designed in two parts: Part 1: a systematic-scoping review, and Part 2: a three-round Delphi consensus method. For Part 1, systematic searches of three electronic databases (PubMed (MEDLINE), Scopus, SPORTDiscus (EBSCOhost)) will be performed from the earliest record. These databases will be searched to identify any sport science and medicine themed studies within women’s rugby. The Preferred Reporting Items for Systematic Reviews and Meta-analyses extension for Scoping Reviews will be adhered to. Part 2 involves a three-round Delphi consensus method to identify future research priorities. Identified experts in women’s rugby will be provided with overall findings from Part 1 to inform decision-making. Participants will then be asked to provide a list of research priority areas. Over the three rounds, priority areas achieving consensus (≥70% agreement) will be identified. This study has received institutional ethical approval. When complete, the manuscript will be submitted for publication in a peer-reviewed journal. The findings of this article will have relevance for a wide range of stakeholders in women’s rugby, including policymakers and governing bodies.

scholarly journals Use of mHealth Technology for Patient-Reported Outcomes in Community-Dwelling Adults with Acquired Brain Injuries: A Scoping Review

2021 ◽  
Vol 18 (4) ◽  
pp. 2173
Author(s):  
Shannon B. Juengst ◽  
Lauren Terhorst ◽  
Andrew Nabasny ◽  
Tracey Wallace ◽  
Jennifer A. Weaver ◽  
...  
Keyword(s):  
Brain Injury ◽  
Scoping Review ◽  
Patient Reported Outcomes ◽  
Brain Injuries ◽  
Community Dwelling ◽  
Ovid Medline ◽  
Affective Symptoms ◽  
Patient Reported ◽  
Mhealth Technology ◽  
Ecological Momentary

The purpose of our scoping review was to describe the current use of mHealth technology for long-term assessment of patient-reported outcomes in community-dwelling individuals with acquired brain injury (ABI). Following PRISMA guidelines, we conducted a scoping review of literature meeting these criteria: (1) civilians or military veterans, all ages; (2) self-reported or caregiver-reported outcomes assessed via mobile device in the community (not exclusively clinic/hospital); (3) published in English; (4) published in 2015–2019. We searched Ovid MEDLINE(R) < 1946 to 16 August 2019, MEDLINE InProcess, EPub, Embase, and PsycINFO databases for articles. Thirteen manuscripts representing 12 distinct studies were organized by type of ABI [traumatic brain injury (TBI) and stroke] to extract outcomes, mHealth technology used, design, and inclusion of ecological momentary assessment (EMA). Outcomes included post-concussive, depressive, and affective symptoms, fatigue, daily activities, stroke risk factors, and cognitive exertion. Overall, collecting patient-reported outcomes via mHealth was feasible and acceptable in the chronic ABI population. Studies consistently showed advantage for using EMA despite variability in EMA timing/schedules. To ensure best clinical measurement, research on post-ABI outcomes should consider EMA designs (versus single time-point assessments) that provide the best timing schedules for their respective aims and outcomes and that leverage mHealth for data collection.

Applications of 3D printing in critical care medicine: A scoping review

2021 ◽  
pp. 0310057X2097665
Author(s):  
Natasha Abeysekera ◽  
Kirsty A Whitmore ◽  
Ashvini Abeysekera ◽  
George Pang ◽  
Kevin B Laupland
Keyword(s):  
Critical Care ◽  
Scoping Review ◽  
A Priori ◽  
Three Dimensional ◽  
Critical Care Medicine ◽  
Future Research ◽  
Care Practice ◽  
Three Dimensional Printing ◽  
Wide Range ◽  
Dimensional Printing

Although a wide range of medical applications for three-dimensional printing technology have been recognised, little has been described about its utility in critical care medicine. The aim of this review was to identify three-dimensional printing applications related to critical care practice. A scoping review of the literature was conducted via a systematic search of three databases. A priori specified themes included airway management, procedural support, and simulation and medical education. The search identified 1544 articles, of which 65 were included. Ranging across many applications, most were published since 2016 in non – critical care discipline-specific journals. Most studies related to the application of three-dimensional printed models of simulation and reported good fidelity; however, several studies reported that the models poorly represented human tissue characteristics. Randomised controlled trials found some models were equivalent to commercial airway-related skills trainers. Several studies relating to the use of three-dimensional printing model simulations for spinal and neuraxial procedures reported a high degree of realism, including ultrasonography applications three-dimensional printing technologies. This scoping review identified several novel applications for three-dimensional printing in critical care medicine. Three-dimensional printing technologies have been under-utilised in critical care and provide opportunities for future research.

Persons With Histories of Traumatic Brain Injury and Problematic Sexual Behavior: An Exploratory Analysis

2021 ◽  
pp. 0306624X2110668
Author(s):  
Carrie C. LeMay ◽  
Jill D. Stinson
Keyword(s):  
Sexual Behavior ◽  
Intellectual Disability ◽  
Brain Injury ◽  
Childhood Maltreatment ◽  
Brain Injuries ◽  
Exploratory Analysis ◽  
Empirical Literature ◽  
Care Group ◽  
Future Research ◽  
Childhood Experiences

Persons with traumatic brain injuries (TBI) who have engaged in problematic or illegal sexual behavior present with complex assessment and intervention needs yet remain understudied within the empirical literature. In the current exploratory analysis, important differences in adaptive and clinical functioning, adverse childhood experiences, and criminal offense history are examined in 25 persons with previous brain injury, 118 persons with intellectual disability but no known TBI, and 103 persons with no history of brain injury or intellectual disability, all of whom have engaged in problematic sexual behavior and who were residing in secure forensic inpatient care. Group differences were examined using comparisons of means and chi-squares. Results highlight important differences in education and employment experiences, diagnostic presentation, exposure to childhood maltreatment, and justice system involvement and characteristics of their sexual offense victims. Associations with prior literature and future research directions are discussed.

scholarly journals Musculoskeletal Injuries Among Females in the Military: A Scoping Review

2020 ◽  
Author(s):  
Pauline Barbeau ◽  
Alan Michaud ◽  
Candyce Hamel ◽  
Danielle Rice ◽  
Becky Skidmore ◽  
...  
Keyword(s):  
Risk Factors ◽  
Scoping Review ◽  
Stress Fractures ◽  
Musculoskeletal Injuries ◽  
Future Research ◽  
Controlled Trials ◽  
Cochrane Central Register ◽  
Increased Risk ◽  
Military Members ◽  
The Military

ABSTRACT Introduction Musculoskeletal injuries (MSKi) are a common challenge for those in military careers. Compared to their male peers, reports indicate that female military members and recruits are at greater risk of suffering MSKi during training and deployment. The objectives of this study were to identify the types and causes of MSKi among female military personnel and to explore the various risk factors associated with MSKi. Materials and Methods A scoping review was conducted over a 4-month time frame of English language, peer-reviewed studies published from 1946 to 2019. Search strategies for major biomedical databases (e.g., MEDLINE; Embase Classic + Embase; and the following EBM Reviews—Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, Database of Abstracts of Reviews of Effects, Health Technology Assessment, and the NHS Economic Evaluation Database) were developed by a senior medical information specialist and included 2,891 titles/abstracts. Study selection and data collection were designed according to the Population, Concept, and Context framework. Studies were included if the study population provided stratified data for females in a military context. Results From a total of 2,287 citations captured from the literature searches, 168 peer-reviewed publications (144 unique studies) were eligible for inclusion. Studies were identified from across 10 countries and published between 1977 and 2019. Study designs were primarily prospective and retrospective cohorts. Most studies assessed both prevalence/incidence and risk factors for MSKi (62.50%), with few studies assessing cause (13.69%). For MSKi of female recruits compared to active female members, the prevalence was higher (19.7%-58.3% vs. 5.5%-56.6%), but the incidence (0.02%-57.7% vs. 13.5%-71.9%) was lower. The incidence of stress fractures was found to be much higher in female recruits than in active members (1.6%-23.9% vs. 2.7%). For anthropometric risk factors, increased body fat was a predictor of MSKi, but not stress fractures. For physiological risk factors for both female military groups, being less physically fit, later menarche, and having no/irregular menses were predictors of MSKi and stress fractures. For biomechanical risk factors, among female recruits, longer tibial length and femoral neck diameter increased the risk of stress fractures, and low foot arch increased risk of an ankle sprain. For female active military members, differences in shoulder rotation and bone strength were associated with risk of MSKi. For biological sex, being female compared to male was associated with an increased risk of MSKi, stress fractures, and general injuries. The consequences of experiencing MSKi for active military included limited duties, time off, and discharge. For recruits, these included missed training days, limited duty days, and release. Conclusions This scoping review provides insight into the current state of the evidence regarding the types and causes of MSKi, as well as the factors that influence MSKi among females in the military. Future research endeavors should focus on randomized controlled trials examining training paradigms to see if women are more susceptible. The data presented in the scoping review could potentially be used to develop training strategies to mitigate some of the identified barriers that negatively impact women from pursuing careers in the military.

Sickness Absence Culture: A Scoping Review

2021 ◽  
Author(s):  
Erlend Pukstad ◽  
Sofie Lorentzen ◽  
Torstein Låg ◽  
Arnstein Mykletun
Keyword(s):  
Sickness Absence ◽  
Scoping Review ◽  
Future Research ◽  
Original Research ◽  
Human Sciences ◽  
Science Base ◽  
Scoping Reviews ◽  
Group Members ◽  
Data Screening ◽  
Broad Overview

Abstract Background: Several studies show that the absence behavior of co-workers’ influence the absence rates of individual group members so that an employee is more likely to be absent when co-workers are often absent. To our knowledge, there are no systematic scoping reviews or other reviews on the concept of sickness absence culture. The objective of this review is to identify and map existing literature on sickness absence culture. We will also investigate what methods and designs are used.Methods: We will be conducting a systematic scoping review with the aim of getting a broad overview of the preexisting literature. This scoping review will consider any publication on sickness absence culture in the field of human sciences, including also reviews, original research, and opinion pieces. The review will be conducted in accordance with the Joanna Briggs Institute (JBI) methodology for scoping reviews and a populated PRISMA-P checklist (Additional file 1). Two reviewers will independently screen all abstracts for inclusion. We will search the electronic databases: MEDLINE, Embase, PsycINFO, Clarivate Web of Science, BASE and CINAHL. We will use Covidence for data screening and extraction. The final stage will include a narrative synthesis of the data.Discussion: The results of this scoping review will contribute to identifying and mapping the existing literature on sickness absence culture, which could facilitate future research on the topic. Systematic review registration: Not registered in publicly accessible registry.

scholarly journals Traumatic Brain Injuries: Unreported and Untreated in an Army Population

2020 ◽  
Vol 185 (Supplement_1) ◽  
pp. 154-160 ◽  
Author(s):  
Sandra M Escolas ◽  
Margie Luton ◽  
Hamid Ferdosi ◽  
Bianca D Chavez ◽  
Scot D Engel
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Medical Care ◽  
Brain Injuries ◽  
Negative Impact ◽  
Traumatic Brain Injuries ◽  
Future Research ◽  
Treatment History ◽  
Anonymous Questionnaire ◽  
The Military

ABSTRACT Introduction In 2008, it was reported that 19.5% of service members previously deployed experienced a mild traumatic brain injury (mTBI). Fifty-seven percent of those did not seek medical care. It was suggested that concerns with seeking care involved confidentiality and career issues. Objective: This study addressed mTBI history, medical treatment history, and stigmas associated with mTBI/concussion. Materials and Methods An anonymous questionnaire was developed. Data collection occurred throughout March 2018 in conjunction with Brain Injury Awareness Month activities. Results All 5,174 volunteers were Army; 86% male; 87% were between 18 and 34 years old; 89% had &lt;14 years in the military; 35% had a combat deployment; and 10% reported having one or more mTBIs in their military careers. Of the Soldiers who reported a concussion, 52% sought medical care. Of those not seeking care, 64% reported they did not think the injury required care, followed by 18% fearing negative impact on their career. Twenty-eight percent who experienced an mTBI versus 11% who have not reported that there is a stigma associated with an mTBI. Conclusions Soldiers sometimes failed to report their suspected concussions and did not seek medical care. Educational efforts may increase reporting of and medical screening for potentially concussive events. Future research to determine the ramifications of unreported and untreated mTBIs/concussions is recommended.

Perinatal Depression

2014 ◽  
Author(s):  
Jennifer N. Felder ◽  
Abigail Lindemann ◽  
Sona Dimidjian
Keyword(s):  
Risk Factors ◽  
Perinatal Depression ◽  
Perinatal Period ◽  
Future Research ◽  
Childbearing Age ◽  
Research Directions ◽  
Wide Range ◽  
Assessment And Treatment ◽  
Future Research Directions ◽  
Assessment Strategies

Depression is a common problem among pregnant andpostpartum women, with rates comparable to or greater than those among women of childbearing age who are not pregnant or postpartum. Perinatal depression is associated with a wide range of unique assessment and treatment complexities, risk factors, and consequences for women and offspring. In this chapter, we review current research on the prevalence of perinatal depression, etiology, risk factors, and consequences, and we discuss assessment strategies and interventions. Limitations to current research and future research directions are noted. We conclude with guidelines for practitioners for assessing and treating depression during the perinatal period.

scholarly journals A Review on Machine and Deep Learning for Semiconductor Defect Classification in Scanning Electron Microscope Images

2021 ◽  
Vol 11 (20) ◽  
pp. 9508
Author(s):  
Francisco López de la Rosa ◽  
Roberto Sánchez-Reolid ◽  
José L. Gómez-Sirvent ◽  
Rafael Morales ◽  
Antonio Fernández-Caballero
Keyword(s):  
Deep Learning ◽  
Electron Microscope ◽  
Scanning Electron Microscope ◽  
Defect Detection ◽  
Scoping Review ◽  
Semiconductor Manufacturing ◽  
Manufacturing Industry ◽  
Future Research ◽  
Wide Range ◽  
Scanning Electron

Continued advances in machine learning (ML) and deep learning (DL) present new opportunities for use in a wide range of applications. One prominent application of these technologies is defect detection and classification in the manufacturing industry in order to minimise costs and ensure customer satisfaction. Specifically, this scoping review focuses on inspection operations in the semiconductor manufacturing industry where different ML and DL techniques and configurations have been used for defect detection and classification. Inspection operations have traditionally been carried out by specialised personnel in charge of visually judging the images obtained with a scanning electron microscope (SEM). This scoping review focuses on inspection operations in the semiconductor manufacturing industry where different ML and DL methods have been used to detect and classify defects in SEM images. We also include the performance results of the different techniques and configurations described in the articles found. A thorough comparison of these results will help us to find the best solutions for future research related to the subject.

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