Persons With Histories of Traumatic Brain Injury and Problematic Sexual Behavior: An Exploratory Analysis

2021 ◽  
pp. 0306624X2110668
Author(s):  
Carrie C. LeMay ◽  
Jill D. Stinson
Keyword(s):  
Sexual Behavior ◽  
Intellectual Disability ◽  
Brain Injury ◽  
Childhood Maltreatment ◽  
Brain Injuries ◽  
Exploratory Analysis ◽  
Empirical Literature ◽  
Care Group ◽  
Future Research ◽  
Childhood Experiences

Persons with traumatic brain injuries (TBI) who have engaged in problematic or illegal sexual behavior present with complex assessment and intervention needs yet remain understudied within the empirical literature. In the current exploratory analysis, important differences in adaptive and clinical functioning, adverse childhood experiences, and criminal offense history are examined in 25 persons with previous brain injury, 118 persons with intellectual disability but no known TBI, and 103 persons with no history of brain injury or intellectual disability, all of whom have engaged in problematic sexual behavior and who were residing in secure forensic inpatient care. Group differences were examined using comparisons of means and chi-squares. Results highlight important differences in education and employment experiences, diagnostic presentation, exposure to childhood maltreatment, and justice system involvement and characteristics of their sexual offense victims. Associations with prior literature and future research directions are discussed.

scholarly journals Traumatic Brain Injuries: Unreported and Untreated in an Army Population

2020 ◽  
Vol 185 (Supplement_1) ◽  
pp. 154-160 ◽  
Author(s):  
Sandra M Escolas ◽  
Margie Luton ◽  
Hamid Ferdosi ◽  
Bianca D Chavez ◽  
Scot D Engel
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Medical Care ◽  
Brain Injuries ◽  
Negative Impact ◽  
Traumatic Brain Injuries ◽  
Future Research ◽  
Treatment History ◽  
Anonymous Questionnaire ◽  
The Military

ABSTRACT Introduction In 2008, it was reported that 19.5% of service members previously deployed experienced a mild traumatic brain injury (mTBI). Fifty-seven percent of those did not seek medical care. It was suggested that concerns with seeking care involved confidentiality and career issues. Objective: This study addressed mTBI history, medical treatment history, and stigmas associated with mTBI/concussion. Materials and Methods An anonymous questionnaire was developed. Data collection occurred throughout March 2018 in conjunction with Brain Injury Awareness Month activities. Results All 5,174 volunteers were Army; 86% male; 87% were between 18 and 34 years old; 89% had <14 years in the military; 35% had a combat deployment; and 10% reported having one or more mTBIs in their military careers. Of the Soldiers who reported a concussion, 52% sought medical care. Of those not seeking care, 64% reported they did not think the injury required care, followed by 18% fearing negative impact on their career. Twenty-eight percent who experienced an mTBI versus 11% who have not reported that there is a stigma associated with an mTBI. Conclusions Soldiers sometimes failed to report their suspected concussions and did not seek medical care. Educational efforts may increase reporting of and medical screening for potentially concussive events. Future research to determine the ramifications of unreported and untreated mTBIs/concussions is recommended.

Childhood Maltreatment and Perinatal Mood and Anxiety Disorders

2016 ◽  
Vol 17 (5) ◽  
pp. 427-453 ◽  
Author(s):  
Karmel W. Choi ◽  
Kathleen J. Sikkema
Keyword(s):  
Anxiety Disorders ◽  
Childhood Maltreatment ◽  
Child Outcomes ◽  
Well Being ◽  
Traumatic Experiences ◽  
Empirical Literature ◽  
Future Research ◽  
Post Traumatic Stress ◽  
Treatment And Prevention ◽  
Mood And Anxiety Disorders

Perinatal mood and anxiety disorders (PMADs) compromise maternal and child well-being and may be influenced by traumatic experiences across the life course. A potent and common form of trauma is childhood maltreatment, but its specific impact on PMADs is not well understood. A systematic review was undertaken to synthesize empirical literature on the relationship between maternal histories of childhood maltreatment and PMADs. Of the 876 citations retrieved, 35 reports from a total of 26,239 participants met inclusion criteria, documenting substantial rates of childhood maltreatment and PMADs. Robust trends of association were observed between childhood maltreatment and perinatal depression, as well as post-traumatic stress disorder, but findings for anxiety were less consistent. Examining multivariate results suggested that childhood maltreatment predicts PMADs above and beyond sociodemographic, psychiatric, perinatal, and psychosocial factors, but may also be partially mediated by variables such as later victimization and moderated by protective early relationships. Future research should test mediating and moderating pathways using prospective cohorts, expanding to cross-cultural settings and other disorder outcomes. Treatment and prevention of childhood maltreatment and its sequelae may help mitigate risk for perinatal psychopathology and its impact on maternal and child outcomes.

Portable electronic assistive technology to improve vocational task completion in young adults with an intellectual disability: A review of the literature

2017 ◽  
Vol 22 (3) ◽  
pp. 213-232 ◽  
Author(s):  
James C Collins ◽  
Lana Collet-Klingenberg
Keyword(s):  
Intellectual Disability ◽  
Reliability And Validity ◽  
Empirical Literature ◽  
Future Research ◽  
Task Completion ◽  
Review Of The Literature ◽  
Work Related ◽  
Research Designs ◽  
Dependent Variables ◽  
Portable Technology

This article summarizes a review of empirical literature from 2000 to 2015 that involved the use of specific portable technology to support persons with an intellectual disability in completing work-related tasks. Nineteen studies were identified for review, with an emphasis on the identification of (a) the characteristics of participants and settings, (b) the types of portable technology and prompting formats used, (c) the research designs utilized, (d) the independent and dependent variables, (e) the measures of reliability and validity, and (f) the overall effectiveness of the interventions. The authors provide an interpretation of the findings as well as the implications of the results and recommended areas for future research.

scholarly journals Temporal patterns of microglial activation in white matter following experimental mild traumatic brain injury: a systematic literature review

2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Prashanth S. Velayudhan ◽  
Nicole Schwab ◽  
Lili-Naz Hazrati ◽  
Anne L. Wheeler
Keyword(s):  
Brain Injury ◽  
White Matter ◽  
Microglial Activation ◽  
Brain Injuries ◽  
Experimental Studies ◽  
Current Understanding ◽  
Future Research ◽  
Cell Integrity ◽  
Experimental Conditions ◽  
Wide Range

AbstractMild traumatic brain injuries (mTBIs) are a prevalent form of injury that can result in persistent neurological impairments. Microglial activation has become increasingly recognized as a key process regulating the pathology of white matter in a wide range of brain injury and disease contexts. As white matter damage is known to be a major contributor to the impairments that follow mTBI, microglia have rightfully become a common target of investigation for the development of mTBI therapies and biomarkers. Recent work has demonstrated that the efficacy of microglial manipulation as a therapeutic intervention following injury or disease is highly time-sensitive, emphasizing the importance of advancing our understanding of the dynamics of post-mTBI microglial activation from onset to resolution. Current reporting of microglial activation in experimental studies of mTBI is non-standardized, which has limited our ability to identify concrete patterns of post-mTBI microglial activation over time. In this review, we examine preclinical studies of mTBI that report on microglial activation in white matter regions to summarize our current understanding of these patterns. Specifically, we summarize timecourses of post-mTBI microglial activation in white matter regions of the brain, identify factors that influence this activation, examine the temporal relationship between microglial activation and other post-mTBI assessments, and compare the relative sensitivities of various methods for detecting microglial activation. While the lack of replicated experimental conditions has limited the extent of conclusions that can confidently be drawn, we find that microglia are activated over a wide range of timecourses following mTBI and that microglial activation is a long-lasting outcome of mTBI that may resolve after most typical post-mTBI assessments, with the exception of those measuring oligodendrocyte lineage cell integrity. We identify several understudied parameters of post-mTBI microglial activation in white matter, such as the inclusion of female subjects. This review summarizes our current understanding of the progression of microglial activation in white matter structures following experimental mTBI and offers suggestions for important future research directions.

scholarly journals A Systematic Scoping Review of New Attention Problems Following Traumatic Brain Injury in Children

2021 ◽  
Vol 12 ◽  
Author(s):  
Sonja Stojanovski ◽  
Shannon E. Scratch ◽  
Benjamin T. Dunkley ◽  
Russell Schachar ◽  
Anne L. Wheeler
Keyword(s):  
Risk Factors ◽  
Brain Injury ◽  
Scoping Review ◽  
Brain Injuries ◽  
Attention Problems ◽  
Future Research ◽  
Original Research ◽  
Neural Basis ◽  
Adhd Diagnosis ◽  
Wide Range

Objective: To summarize existing knowledge about the characteristics of attention problems secondary to traumatic brain injuries (TBI) of all severities in children.Methods: Computerized databases PubMed and PsychINFO and gray literature sources were used to identify relevant studies. Search terms were selected to identify original research examining new ADHD diagnosis or attention problems after TBI in children. Studies were included if they investigated any severity of TBI, assessed attention or ADHD after brain injury, investigated children as a primary or sub-analysis, and controlled for or excluded participants with preinjury ADHD or attention problems.Results: Thirty-nine studies were included in the review. Studies examined the prevalence of and risk factors for new attention problems and ADHD following TBI in children as well as behavioral and neuropsychological factors associated with these attention problems. Studies report a wide range of prevalence rates of new ADHD diagnosis or attention problems after TBI. Evidence indicates that more severe injury, injury in early childhood, or preinjury adaptive functioning problems, increases the risk for new ADHD and attention problems after TBI and both sexes appear to be equally vulnerable. Further, literature suggests that cases of new ADHD often co-occurs with neuropsychiatric impairment in other domains. Identified gaps in our understanding of new attention problems and ADHD include if mild TBI, the most common type of injury, increases risk and what brain abnormalities are associated with the emergence of these problems.Conclusion: This scoping review describes existing studies of new attention problems and ADHD following TBI in children and highlights important risk factors and comorbidities. Important future research directions are identified that will inform the extent of this outcome across TBI severities, its neural basis and points of intervention to minimize its impact.

Group Intervention for Adolescents With Chronic Acquired Brain Injury: The Future Zone

2010 ◽  
Vol 20 (4) ◽  
pp. 111-119
Author(s):  
Ellen M. Hickey ◽  
Jennifer N. Saunders
Keyword(s):  
Brain Injury ◽  
Group Intervention ◽  
Intervention Program ◽  
Brain Injuries ◽  
Acquired Brain Injury ◽  
Intervention Programs ◽  
Future Research ◽  
Strength Based ◽  
Self Knowledge ◽  
Psychosocial Challenges

Introduction: Acquired brain injury (ABI) is a common cause of social cognition deficits and psychosocial challenges in adolescents. A group intervention program was designed to support teens with chronic ABI. Method: Quantitative and qualitative analyses were conducted to examine participants' self-knowledge and satisfaction with the program. Results: Results revealed that participants and parents valued increased self-knowledge and an understanding of brain injuries, the focus on friendships and individual strengths, and feelings of togetherness and not being judged. Discussion: Support for strength-based, project-oriented, group intervention programs for adolescents with ABI and directions for future research are discussed.

Adverse Childhood Experiences of Violent Female Offenders: A Comparison of Homicide and Sexual Perpetrators

2017 ◽  
Vol 62 (8) ◽  
pp. 2312-2328 ◽  
Author(s):  
Dawn M. Pflugradt ◽  
Bradley P. Allen ◽  
Amanda J. Zintsmaster
Keyword(s):  
Sex Offenders ◽  
Childhood Maltreatment ◽  
Adverse Childhood Experiences ◽  
Female Offenders ◽  
Future Research ◽  
Childhood Experiences ◽  
Sexual Offenses ◽  
Violent Offending ◽  
Adverse Childhood ◽  
Increased Risk

Adverse childhood experiences are associated with a multitude of health and social problems. In addition to an increased risk of poor health, mental disorders, and substance abuse, childhood maltreatment is also significantly related to adult violent offending. Although gender-specific analyses suggest that early childhood maltreatment precedes later violence for males across offense categories, it is unknown whether this association also applies to different types of female offenders. This study explores the types and quantity of adverse childhood experiences for two groups of violent female offenders: perpetrators of intentional homicide ( N = 28) and perpetrators of sexual offenses ( N = 47). A nonparametric analysis using odds ratios (OR) indicated that female homicide perpetrators experienced significantly more adverse childhood experiences (as measured by the Adverse Childhood Experiences Questionnaire) than female sex offenders. Implications for future research are discussed.

scholarly journals A Pro-social Pill? The Potential of Pharmacological Treatments to Improve Social Outcomes After Pediatric Traumatic Brain Injury

2021 ◽  
Vol 12 ◽  
Author(s):  
Bridgette D. Semple ◽  
Ramesh Raghupathi
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Social Behavior ◽  
Early Life ◽  
Brain Injuries ◽  
Time Window ◽  
Therapeutic Interventions ◽  
Future Research ◽  
Clinical Literature ◽  
The Impact

Traumatic brain injury (TBI) is a leading cause of injury-induced disability in young children worldwide, and social behavior impairments in this population are a significant challenge for affected patients and their families. The protracted trajectory of secondary injury processes triggered by a TBI during early life—alongside ongoing developmental maturation—offers an extended time window when therapeutic interventions may yield functional benefits. This mini-review explores the scarce but promising pre-clinical literature to date demonstrating that social behavior impairments after early life brain injuries can be modified by drug therapies. Compounds that provide broad neuroprotection, such as those targeting neuroinflammation, oxidative stress, axonal injury and/or myelination, may prevent social behavior impairments by reducing secondary neuropathology. Alternatively, targeted treatments that promote affiliative behaviors, exemplified by the neuropeptide oxytocin, may reduce the impact of social dysfunction after pediatric TBI. Complementary literature from other early life neurodevelopmental conditions such as hypoxic ischemic encephalopathy also provides avenues for future research in neurotrauma. Knowledge gaps in this emerging field are highlighted throughout, toward the goal of accelerating translational research to support optimal social functioning after a TBI during early childhood.

A Systematic Review of the Biological Correlates and Consequences of Childhood Maltreatment and Adverse Childhood Experiences

2021 ◽  
pp. 152483802110216
Author(s):  
Eric M. Cooke ◽  
Eric J. Connolly ◽  
Danielle L. Boisvert ◽  
Brittany E. Hayes
Keyword(s):  
Systematic Review ◽  
Childhood Maltreatment ◽  
Adverse Childhood Experiences ◽  
Later Life ◽  
Risk Scores ◽  
Future Research ◽  
Childhood Experiences ◽  
Adverse Childhood ◽  
System Functioning ◽  
The Life Course

Childhood maltreatment (CM) and adverse childhood experiences (ACEs) are two primary forms of interpersonal victimization that have been associated with a host of deleterious health outcomes. Studies over the past decade have begun to use a range of biologically informed methods to better understand the role biology plays in the relationship between CM, ACEs, and later life outcomes. This line of research has shown that both forms of victimization occur at sensitive periods of development, which can increase the likelihood of “getting under the skin” and influence health and behavior across the life course. This review examines the current state of knowledge on this hypothesis. One hundred and ninety-nine studies are included in this systematic review based on criteria that they be written in English, use a biologically informed method, and be conducted on samples of humans. Results reveal that latent additive genetic influences, biological system functioning captured by biomarkers, polygenic risk scores, and neurobiological factors are commonly associated with exposure and response to CM and ACEs. The implication of these findings for the existing body of research on early life victimization and recommendations for future research and policy are discussed.

scholarly journals A hybrid method for traumatic brain injury lesion segmentation

2022 ◽  
Vol 12 (2) ◽  
pp. 1437
Author(s):  
Ahmad Yahya Dawod ◽  
Aniwat Phaphuangwittayakul ◽  
Salita Angkurawaranon
Keyword(s):  
Image Segmentation ◽  
Brain Injury ◽  
Brain Injuries ◽  
Free Form ◽  
Future Research ◽  
Normal Brain ◽  
Object Model ◽  
Brain Hemorrhage ◽  
Segmentation Approach ◽  
Segmentation Image

<span>Traumatic brain injuries are significant effects of disability and loss of life. Physicians employ computed tomography (CT) images to observe the trauma and measure its severity for diagnosis and treatment. Due to the overlap of hemorrhage and normal brain tissues, segmentation methods sometimes lead to false results. The study is more challenging to unitize the AI field to collect brain hemorrhage by involving patient datasets employing CT scans images. We propose a novel technique free-form object model for brain injury CT image segmentation based on superpixel image processing that uses CT to analyzing brain injuries, quite challenging to create a high outstanding simple linear iterative clustering (SLIC) method. The maintains a strategic distance of the segmentation image to reduced intensity boundaries. The segmentation image contains marked red hemorrhage to modify the free-form object model. The contour labelled by the red mark is the output from our free-form object model. We proposed a hybrid image segmentation approach based on the combined edge detection and dilation technique features. The approach diminishes computational costs, and the show accomplished 96.68% accuracy. The segmenting brain hemorrhage images are achieved in the clustered region to construct a free-form object model. The study also presents further directions on future research in this domain.</span>

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