scholarly journals Comparison of Defined Course Doses (DCDvet) for Blanket and Selective Antimicrobial Dry Cow Therapy on Conventional and Organic Farms

Animals ◽  
2019 ◽  
Vol 9 (10) ◽  
pp. 707 ◽  
Author(s):  
Clair Firth ◽  
Annemarie Käsbohrer ◽  
Christa Egger-Danner ◽  
Klemens Fuchs ◽  
Beate Pinior ◽  
...  

Antimicrobial use in livestock production is a controversial subject. While antimicrobials should be used as little as possible, it is still necessary, from both an animal health and welfare point of view, to treat infected animals. The study presented here aimed to analyse antimicrobial use on Austrian dairy farms by calculating the number of Defined Course Doses (DCDvet) administered per cow and year for dry cow therapy. Antimicrobial use was analysed by production system and whether farmers stated that they used blanket dry cow therapy (i.e., all cows in the herd were treated) or selective dry cow therapy (i.e., only cows with a positive bacteriological culture or current/recent history of udder disease were treated). A statistically significant difference (p < 0.001) was determined between antimicrobial use for blanket (median DCDvet/cow/year: 0.88) and selective dry cow therapy (median DCDvet/cow/year: 0.41). The difference between antimicrobial use on conventional and organic farms for dry cow therapy as a whole, however, was not statistically significant (p = 0.22) (median DCDvet/cow/year: 0.68 for conventional; 0.53 for organic farms). This analysis demonstrates that selective dry cow therapy leads to a lower overall use of antimicrobials and can assist in a more prudent use of antimicrobials on dairy farms.

Author(s):  
О.А. Матвейчев

Гермотим из Клазомен – фигура в истории греческой философии, можно сказать, маргинальная. В современной литературе он появляется разве что в ряду других колдунов и мистиков VII–VI вв. до н.э. В таком статусе он включается и в собрание Дильса. Анализируя сведения о Гермотиме, автор ставит перед собой цель найти ему место среди малоазийских философов первой величины, которых считают основателями греческой философии. Различение духа (души) и материи (тела) станет основополагающим принципом греческой философии, понятие Ума (нуса) выступит фундаментом для системы Анаксагора, первого афинского философа, с которого, собственно, и начнется история классической греческой философии. Автор разделяет точку зрения Э. Доддса и др., что появление нового для Греции представления о различии души и тела коренится в северной (гиперборейской?) ментальности, привнесенной в греческий мир во времена колонизации VII–VI вв. до н.э., а возможно – и в более ранние. Ключевые слова: история философии, Древняя Греция, Гиперборея, Гермотим из Клазомен, Анаксагор, шаманизм, нус, душа, тело Hermotimus of Clazomenae can be called a marginal figure in the history of Greek philosophy. In modern literature he is mentioned only among other sorcerers and mystics of the VIIth–VIth centuries BC. The collection of Hermann Diels describes him in the same manner. Analyzing available information about Hermotimus, the author makes an attempt to place him among the primary Anatolian philosophers who are considered the founders of Greek philosophy. The distinction between spirit (soul) and matter (body) will become the fundamental principle of Greek philosophy; the concept of Nous (cosmic Mind) will be the foundation for the system of Anaxagoras, the first Athenian philosopher, from which, in fact, the history of classical Greek philosophy begins. The author shares the point of view of E. Dodds and others that the emergence of a new concept about the difference between soul and body in Greece is rooted in the northern (Hyperborean?) mentality introduced into the Greek world during the colonization of the VIIth–VIth centuries BC or possibly in earlier times. Keywords: history of philosophy, Ancient Greece, Hyperborea, Hermotimus of Clazomenae, Anaxagoras, shamanism, nous, soul, body


2013 ◽  
Vol 1 (1) ◽  
pp. 1
Author(s):  
Hanif Cahyo Adi Kistoro

This research aims at examining the difference of aggressiveness in students Senior High School of First Muhammedan (SMU MUHI) Yogyakarta from parent’s rearings and parent’s jobs. It based on phenomenons, such  increase of fights along students, behaviors of students less polite to teachers, and others, especially that occurs in Yogyakarta. It indicated of aggressive behaviour. It may be caused of not right of parent’s rearings, and parent’s rearings has correlation with parent’s jobs. From these phenomenons, reseacher want to investigated about difference of aggressiveness in students Senior High School of First Muhammedan from parent’s rearings (authoritarian, democratic, and permissive) and from parent’s jobs (entrepreneur, official civil servant/PNS, and military) point of view to aggressiveness. Two hypotheses tested are as follows: (a) that there is a difference of agressiveness in students Senior High School of First Muhammedan (SMU MUHI) have parents tendency to authoritatif, democratic, and permissive, and b) that there is a difference of agressiveness in students Senior High School of First Muhammedan (SMU MUHI) have parents as entrepreneur, official civil servant, and military. Subjects of the research include seventy six students of first class and sixty seven students of second class in Senior High School of First Muhammedan (SMU MUHI), Yogyakarta and their parents, totally is one hundred and sixty person. The two instruments administered in data gathering (quantitative data) include parent’s rearings scale for students’ parent (within there was a identity of parent’s job), agressiveness scale for students, and interview (qualitative data). Variance analysis 2-stripes (Anava 2-jalur) were applied to analyze the data. The outcome shows the following: (a) there is a significant difference of three parent’s rearings to bring about aggressiveness with F=366.479, standar error p=0.000, and difference average is: authoritarian=69.344; democratic=79.283; permissive=87.862. (b) there is not a significant difference of three parent’s jobs to bring about aggressiveness with F=0.054, standar error p=0.583, and difference  average is: entrepreneur=77.632; official civil servant=76.436; military=76.960. From the result of parent’s rearings appeared that permissive is the most influential from all (authoritarian and democratic) to bring about aggressiveness in students of Senior High School of First Muhhammedan, Yogyakarta, and parent’s rearings hasn’t influence to bring about children’s aggressiveness.


2020 ◽  
Vol 11 (3) ◽  
pp. 31-36
Author(s):  
Satyajit Bagudai ◽  
Hari Prasad Upadhyay

Introduction: Studies have reported that off springs of hypertensive parents are more likely to develop hypertension. Affection of target organ starts even before the diagnosis of hypertension. Autonomic dysfunction may be the initial cardiac effects in the pathogenesis of hypertension. Till now very few studies have been done to find the early outcomes in the cardiac autonomic functions in the normotensive siblings of hypertensive patients. Heart rate recovery after exercise is a useful marker for cardiac autonomic function. Since the etio-pathogenesis of hypertension is expected to affect the autonomic cardiovascular parameters even before the prehypertensive stage, the following study was carried out to analyze the heart rate recovery, in the descendent non- hypertensive young adults with and without parental history of hypertension. Aim and objective: This research study was aimed to study the quantify and compare the difference (if any) of heart rate recovery in response to 3minute step test between non hypertensive children of non- hypertensive and hypertensive parents within an age group of 18-22 years. Material &Methods: A total of 63 normotensive students were divided into one hypertensive parents(HP) group containing students with parental history of hypertension) and one non hypertensive parents group (NHP) having students without parental history of hypertension). Each student was subjected to 3 minute Master step test. Recordings of heart rate were made before and after exercise. Heart rate recovery index (HRRI) of 1minute (HRRI1), as well as in 2, 3 and 4 minute (HRRI2, HRRI3, HRRI4) were calculated and analyzed. Results: The resting (basal) heart rate as well as 1st minute heart rate recovery index (HRRI1) was not significantly different in the two groups. Likewise, the 2nd minute (HRRI2), 3rd minute (HRRI3), and 4th minute HRRI (HRR4) respectively were also not significantly different between the two groups. Conclusion: This study concluded that there is no significant difference in heart rate recovery among non-hypertensive young adults, with and without parental history of hypertension.


1989 ◽  
Vol 1 (1) ◽  
pp. 12-15 ◽  
Author(s):  
Lorraine J. Hoffman

The conventional culture method was compared to coagglutination for detection of Actinobacillus (Haemophilus) pleuropneumoniae in 425 sets of pig lungs. Sera from the same animals were evaluated for antibodies to A. pleuropneumoniae by the complement fixation (CF) test. All samples were collected at 2 packing plants in Iowa. In 2 nonvaccinated herds with no history of respiratory disease, the difference between standard culture results and coagglutination was highly significant ( P < 0.001). None of the 57 pigs in this group were positive for A. pleuropneumoniae by conventional culture, but 7 were positive by the coagglutination test. There were 15 animals with CF titers between 1:8 and 1:32. Animals from 6 herds vaccinated for A. pleuropneumoniae and without recent respiratory problems were evaluated. One out of 118 animals tested was positive for A. pleuropneumoniae by standard culture as compared to 9 positive by coagglutination. The difference in positive results between culture and coagglutination was highly significant ( P < 0.001). Twenty-eight animals had CF titers to A. pleuropneumoniae (1:4 to ≥ 1: 128). Two hundred fifty lungs and sera samples were collected from 7 herds which had recently experienced varying degrees of respiratory disease. Thirty-nine lungs were positive for A. pleuropneumoniae by culture and 182 were positive by coagglutination. The number of positives detected by coagglutination was significantly different ( P < 0.001) from the number positive by culture. There were 172 animals with antibody titers ranging from suspect to ≥ 1:128. There were significantly fewer positive animals detected by standard culture than with the CF test ( P < 0.001). There was no significant difference between coagglutination results and CF titers when a titer of 1:4 was used as the positive threshold.


2019 ◽  
Vol 67 (5) ◽  
pp. 729-743 ◽  
Author(s):  
Jürgen Habermas

Abstract Ever since Hegel made poignant the difference between morality and ethical life (“Sittlichkeit”), philosophical discourse in the traditions that developed subsequently, up to and including the Frankfurt school, has oscillated between those poles. This paper starts out with a short exposition of autonomy as one of the few large-scale innovations in the history of philosophy and then proceeds to discuss Hegel’s concept of “Sittlichkeit” and the objections to be raised against it from a Kantian point of view. Political theory, however, has to move beyond pure normativism and consider actual social relations of power, as Marx disclosed. Mapping out this winding trajectory from Kant to Marx provides some perspective that may be illuminating for challenging present-day issues.


Animals ◽  
2019 ◽  
Vol 9 (8) ◽  
pp. 485
Author(s):  
Megan Wilson ◽  
Jess Williams ◽  
V. Tamara Montrose ◽  
Jane Williams

Most stallions within breeding programmes are expected to breed and compete concurrently. The exercising of stallions with regards to training regimes during the breeding season is a controversial subject. Daily exercise at low intensities is important for the mental and reproductive well-being of the stallion, however higher intensities of exercise, as seen in competing stallions, may have detrimental effects on seminal quality. To calculate if competition does affect semen quality, this study investigated the effect that equestrian discipline and timing of competition had on a range of stallion semen characteristics. This was a retrospective study that evaluated the seminal data of 1130 stallion semen collections from two UK based stud farms between 2009 and 2016. Competing stallion semen quality was significantly lower with regards to concentration (p < 0.05) and progressive motility (p < 0.05) than non-competing stallions. Semen volume was higher in competing stallions (p < 0.05) than non-competing stallions. There was a significant difference in seminal attributes among disciplines and competition levels (p < 0.05). The difference in semen quality among competing and non-competing stallions, as well as the difference among disciplines suggests endocrinological and physiological changes occur in relation to training intensity and competition.


2020 ◽  
pp. 108705471989685 ◽  
Author(s):  
Sherrill J. Rose ◽  
Matthew A. Hathcock ◽  
Wendy M. White ◽  
Kristi Borowski ◽  
Enid Y. Rivera-Chiauzzi

Objective: A retrospective cohort study was performed to evaluate whether birthweight was less among infants of women taking amphetamine–dextroamphetamine during pregnancy at our academic institution. Method: We identified mother–infant pairs with documented exposure to amphetamine–dextroamphetamine in pregnancy from 2005 through 2015. Patients were matched 2:1 with unexposed controls. Charts were reviewed for known causes of intrauterine growth restriction. Analysis of birthweight used generalized estimating equation blocking on matching. Medical histories were analyzed with χ2 test or Fisher’s exact test. Results: We identified 53 exposed mother–infant pairs. The difference in mean birthweight of infants exposed to amphetamine–dextroamphetamine versus those not exposed was 26.9 g, which is not significant (95% confidence interval [CI] = [−141, 195 g]; p = .75). A significant difference was noted for exposed versus unexposed mothers for comorbid psychiatric illness and history of substance abuse ( p < .001). Conclusion: With a limited sample size, our study suggests no significant difference in birthweight.


1973 ◽  
Vol 8 (1) ◽  
pp. 24-47 ◽  
Author(s):  
Ghiţa Ionescu

MOST STUDENTS OF SAINT-SIMON HAVE BEEN ESPECIALLY CONCERNED with his relations with the different 19th-century ideological movements; hence few have approached his work from the point of view of the incompatibility between his attitudes and those of the Jacobins. Yet such an approach re-situates his intellectual biography in its proper context – and indeed protects his work from the anachronistic interpretations which have plagued it in the history of ideas. Moreover it illuminates even more rewardingly his present relevance. His clash with Jacobinism might be taken as the startingpoint of the opposition between Jacobinism and industrialism, between the modern industrial societies and the ‘politics of power’ of the old centralized nation states. From this then derives his theory of the difference between the politics of power and the politics of abilities. The importance of this theory, especially for political science, has not been sufficiently stressed in the classic studies on Saint-Simon's work. Mostly sociological, these studies are divided amongst themselves on whether his work must be seen as socialism, Utopian or otherwise, or as elitism, technocratic or otherwise. And yet it is this theory which provides the logical link between these two seemingly contradictory interpretations.


2021 ◽  
Vol 37 (1) ◽  
Author(s):  
Tamer M. Attia ◽  
Ahmad M. Hamdan

Abstract Background Olfaction is a complex process involving different neurological mechanisms with a correlation between the chemical structure and quality of odors regarding pleasantness. This study aimed to compare the detection of pleasant and unpleasant odors in different grades of hyposmia. A descriptive cross-sectional study was conducted preceded by a preliminary pilot study, including 20 normal subjects without a history of hyposmia. The pilot study was carried out using the University of Pennsylvania Smell Identification Test (UPSIT) with the assessment of pleasantness of odors using a visual analog scale (VAS). Fifty patients diagnosed with organic hyposmia/anosmia were included in the main study and assessed for the degree of hyposmia/anosmia using UPSIT. The number of detected odors out of the five odors with highest VAS for pleasantness and five odors with lowest VAS for pleasantness, as detected by the pilot study, for every patient was assessed and compared. Results There was a significant difference between the detection of pleasant and unpleasant odors in mild, moderate, and severe hyposmia (p value = 0.02, 0.005, and 0.03 respectively) with a highly significant difference in the whole study group ( p < 0.00001) with more loss of ability to detect unpleasant odors compared with pleasant odors. Conclusion The current study showed significantly less ability to detect unpleasant odors compared with pleasant odors in different grades of hyposmia. This finding suggests that the pattern of degeneration of the olfactory sense organ is not uniform with the topographic nature of the olfactory membrane.


2021 ◽  
Vol 23 (Supplement_G) ◽  
Author(s):  
Francesca Heilbron ◽  
Mara Gavazzoni ◽  
Diana Florescu ◽  
Roberto Ochoa ◽  
Michele Tomaselli ◽  
...  

Abstract Aims Atrial and ventricular functional tricuspid regurgitation (A-FTR and V-FTR) have recently emerged as different phenotypes of FTR. Given the difference in mechanisms that are postulated to be underlying these two entities, a different remodelling of tricuspid valve (TV) apparatus can occur and therefore also a specific quantitative approach could be deemed. Moreover, considered the known limitation of the two-dimensional flow convergence method (2D-PISA) for quantifying FTR in advanced valve apparatus remodelling with irregular effective valve orifice (ERO) morphology, it would be expected that also the parameters of severity of FTR can be different in these two types of FTR. The aim of this study was to investigate the TV apparatus remodelling in the two different phenotypes of FTR: ventricular (V-FTR) and atrial (A-FTR) and the role of echocardiographic parameters of TV remodelling and TR severity to predict clinical outcomes. Methods and results The present retrospective study included consecutive patients with moderate to severe functional tricuspid regurgitation (FTR) referred for echocardiography in two Italian centres. The composite endpoint of death for any cause and heart failure (HF) hospitalization was used as primary outcome of this analysis. According to more recent guidelines, patients were considered having A-FTR if having history of long-standing atrial fibrillation, without history of pulmonary hypertension and left side heart disease. A total of 180 patients were included. Despite the right atrial volume (RAV) was not different in the two groups, in A-FTR tethering height was significantly lower (11.7 ± 4.8 mm vs. 15.0 ± 5.5 in V-FTR. P &lt; 0.01) and the 3D-derived tricuspid annulus (TA) diameters were larger both in end-diastolic and mid-systolic phase (3D-TA-End diastolic-major axis: 45.2 ± 6.2 mm in A-FTR vs. 42.8 ± 5.4 in V-FTR. P = 0.04; 3D-TA mid systolic major axis: 41.7 ± 6.4 mm in A-FTR vs. 37.9 ± 5.1 in V-FTR, P &lt; 0.01). 3D-TA-End diastolic-minor axis: 39.7 ± 6.8 vs. 37.1 ± 5.2. P = 0.03. Regarding the parameters of severity of FTR, patients with V-FTR had larger vena contracta (VC), either when 2D estimated or 3D (2D-VC-average: 5.3 ± 2.8 mm in A-FTR vs. 6.6 ± 3.7 in V-FTR. P = 0.02; 3D-VCA: 0.9 ± 0.4 cm2 vs. 1.3 ± 1.1 cm2, P = 0.02); conversely the value of 2D-ERO and regurgitant volume estimated with 2D-PISA method did not show significant difference between the two groups. After a median follow-up of 24 months (IQR: 2–48) 72 patients (40%) reached the primary endpoint and 64 (36%) hospitalized for HF. Different predictors of combined endpoint were found in the two groups: tenting height. 2D-VC. 3D-VCA and regurgitant fraction were prognostic correlates in V-FTR; TA dimensions as well as all the parameters of severe TR, including EROA with PISA method were related to the prognosis in A-FTR. Conclusions Different TV remodelling occurs in patients with A- and V-FTR, having the second more pronounce tethering of TV leaflets; the prognostic role of quantitative parameters of FTR in these two groups is different, thus reaffirming: (1) the limitation of PISA method without correction in case of more pronounced tenting of leaflets; (2) the difference in underlying pathogenic mechanisms; and (3) the needing for a more specific diagnostic approach and prognostic stratification in these two FTR phenotypes.


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