Antioxidant Properties of Water-Soluble Gum from Flaxseed Hulls

Fisetin is a natural antioxidant with a wide range of nutraceutical properties, including antidiabetic, neuroprotecting, and suppression or prevention of tumors. The present work describes the preparation of a water-soluble, solid inclusion compound of fisetin with gamma-cyclodextrin (γ-CD), a cyclic oligosaccharide approved for human consumption. A detailed physicochemical analysis of the product is carried out using elemental analysis, powder X-ray diffraction (PXRD), Raman, infrared and 13C{1H} CP-MAS NMR spectroscopies, and thermal analysis (TGA) to verify fisetin inclusion and to present a hypothetical structural arrangement for the host–guest units. The antioxidant activity of the γ-CD·fisetin inclusion compound is evaluated by the DPPH assay.

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Analysis of biochemical composition and antioxidant properties of nuts sold in the consumer marke

Proceedings of the Voronezh State University of Engineering Technologies ◽

10.20914/2310-1202-2020-2-124-130 ◽

2020 ◽

Vol 82 (2) ◽

pp. 124-130

Author(s):

L. P. Nilova ◽

S. M. Malyutenkova

Keyword(s):

Fatty Acids ◽

Vitamin E ◽

Phenolic Compounds ◽

Biochemical Composition ◽

Unsaturated Fatty Acids ◽

Antioxidant Properties ◽

Water Soluble ◽

Total Phenolic ◽

Consumer Market ◽

Triton X

The results of studies of the biochemical composition and antioxidant properties of nuts sold in the consumer market of St. Petersburg were presented in the work. The objects of research were kernels of nuts: sweet almonds, hazelnuts, cashews, walnuts. Total Soxhlet lipids, fatty acid composition, vitamin E, fractional composition of tocopherols and phytosterols, total phenolic compounds and flavonoids, antioxidant activity by FRAP with ferric chloride, o-phenanthroline and Triton X 100 were determined in nuts. Nuts varied in lipid content (42.6–65.4%) with a predominance of unsaturated fatty acids from 80.4 to 92.4 relative%. Oleic acid prevailed in the fatty acids of almonds, hazelnuts and cashews, while linoleic acid prevailed in walnuts. Walnuts contained the highest amount of polyunsaturated fatty acids. The antioxidant properties of nuts were formed by a complex of water and fat-soluble antioxidants. Fat-soluble antioxidants included vitamin E with a predominance of ?-tocopherol in the kernels of sweet almonds and hazelnuts, ?-tocopherol - in walnuts and cashews. Only sweet almond kernels contained all the tocopherol fractions. ?- and ?-tocopherols were absent in hazelnut lipids, while ?-tocopherols were absent in cashews and walnuts. ?-sitosterol, campesterol and stigmasterol with a predominance of ?-sitosterol were identified in the composition of phytosterols in all nut kernels. Water-soluble antioxidants are mainly represented by phenolic compounds, the amount of which varies widely depending on the type of nuts: cashews

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Antioxidant properties of water-soluble polysaccharides from Antrodia cinnamomea in submerged culture

Food Chemistry ◽

10.1016/j.foodchem.2007.01.018 ◽

2007 ◽

Vol 104 (3) ◽

pp. 1115-1122 ◽

Cited By ~ 64

Author(s):

Ming-Chi Tsai ◽

Tuzz-Ying Song ◽

Ping-Hsiao Shih ◽

Gow-Chin Yen

Keyword(s):

Submerged Culture ◽

Antioxidant Properties ◽

Water Soluble ◽

Antrodia Cinnamomea

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Apple Pomace Extract as a Sustainable Food Ingredient

Antioxidants ◽

10.3390/antiox8060189 ◽

2019 ◽

Vol 8 (6) ◽

pp. 189 ◽

Cited By ~ 18

Author(s):

Pedro A. R. Fernandes ◽

Sónia S. Ferreira ◽

Rita Bastos ◽

Isabel Ferreira ◽

Maria T. Cruz ◽

...

Keyword(s):

Solid Phase ◽

Antioxidant Properties ◽

Water Extract ◽

Apple Pomace ◽

Water Soluble ◽

Hot Water ◽

Array Detector ◽

Food Ingredient ◽

Sustainable Solutions

Apple pomace is a by-product of apple processing industries with low value and thus frequent disposal, although with valuable compounds. Acidified hot water extraction has been suggested as a clean, feasible, and easy approach for the recovery of polyphenols. This type of extraction allowed us to obtain 296 g of extract per kg of dry apple pomace, including 3.3 g of polyphenols and 281 g of carbohydrates. Ultrafiltration and solid-phase extraction using C18 cartridges of the hot water extract suggested that, in addition to the apple native polyphenols detected by ultra-high-pressure liquid chromatography coupled to a diode-array detector and mass spectrometry UHPLC-DAD-ESI-MSn, polyphenols could also be present as complexes with carbohydrates. For the water-soluble polyphenols, antioxidant and anti-inflammatory effects were observed by inhibiting chemically generated hydroxyl radicals (OH•) and nitrogen monoxide radicals (NO•) produced in lipopolysaccharide-stimulated macrophages. The water-soluble polyphenols, when incorporated into yogurt formulations, were not affected by fermentation and improved the antioxidant properties of the final product. This in vitro research paves the way for agro-food industries to achieve more diversified and sustainable solutions towards their main by-products.

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Antioxidant Properties of Fullerene Derivatives Depend on Their Chemical Structure: A Study of Two Fullerene Derivatives on HELFs

Oxidative Medicine and Cellular Longevity ◽

10.1155/2019/4398695 ◽

2019 ◽

Vol 2019 ◽

pp. 1-13 ◽

Cited By ~ 8

Author(s):

Vasilina Sergeeva ◽

Olga Kraevaya ◽

Elizaveta Ershova ◽

Larisa Kameneva ◽

Elena Malinovskaya ◽

...

Keyword(s):

Oxidative Stress ◽

Chemical Structure ◽

Antioxidant Properties ◽

Water Soluble ◽

Lung Fibroblasts ◽

Human Embryonic Lung ◽

Fullerene Derivatives ◽

The Past ◽

Wide Range ◽

Short Times

Oxidative stress is a major issue in a wide number of pathologies (neurodegenerative, cardiovascular, immune diseases, and cancer). Because of this, the search for new antioxidants is an important issue. One of the potential antioxidants that has been enthusiastically discussed in the past twenty years is fullerene and its derivatives. Although in aqueous solutions fullerene derivatives have shown to be antioxidants, their properties in this regard within the cells are controversially discussed. We have studied two different water-soluble fullerene C60 and C70 derivatives on human embryonic lung fibroblasts at a wide range of concentrations. Both of them cause a decrease in cellular ROS at short times of incubation (1 hour). Their prolonged action, however, is fundamentally different: derivative GI-761 causes secondary oxidative stress whereas derivative VI-419-P3K keeps ROS levels under control values. To gain a better understanding of this effect, we assessed factors that could play a role in the response of cells to fullerene derivatives. Increased ROS production occurred due to NOX4 upregulation by GI-761. Derivative VI-419-P3K activated the transcription of antioxidant master regulator NRF2 and caused its translocation to the nucleus. This data suggests that the antioxidant effect of fullerene derivatives depends on their chemical structure.

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Synthesis, characterization, solution and antioxidant properties of novel tetrakis{4-[N-((3-dimethylamino)propyl)amide]phenoxy}nickel (II) phthalocyanine and its water soluble derivatives

Journal of Organometallic Chemistry ◽

10.1016/j.jorganchem.2016.09.019 ◽

2016 ◽

Vol 823 ◽

pp. 83-89 ◽

Cited By ~ 11

Author(s):

Senem Çolak ◽

Sibel Kahraman ◽

Salih Zeki Yıldız

Keyword(s):

Antioxidant Properties ◽

Water Soluble

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Polyhydroxyfullerene Binds Cadmium Ions and Alleviates Metal-Induced Oxidative Stress in Saccharomyces cerevisiae

Applied and Environmental Microbiology ◽

10.1128/aem.01329-14 ◽

2014 ◽

Vol 80 (18) ◽

pp. 5874-5881 ◽

Cited By ~ 10

Author(s):

Arunava Pradhan ◽

José Paulo Pinheiro ◽

Sahadevan Seena ◽

Cláudia Pascoal ◽

Fernanda Cássio

Keyword(s):

Oxidative Stress ◽

Saccharomyces Cerevisiae ◽

Antioxidant Properties ◽

Water Soluble ◽

Interactive Effects ◽

Membrane Disruption ◽

Dependent Manner ◽

Extracellular Medium ◽

Cadmium Ions ◽

Ph Dependent

ABSTRACTThe water-soluble polyhydroxyfullerene (PHF) is a functionalized carbon nanomaterial with several industrial and commercial applications. There have been controversial reports on the toxicity and/or antioxidant properties of fullerenes and their derivatives. Conversely, metals have been recognized as toxic mainly due to their ability to induce oxidative stress in living organisms. We investigated the interactive effects of PHF and cadmium ions (Cd) on the model yeastSaccharomyces cerevisiaeby exposing cells to Cd (≤5 mg liter−1) in the absence or presence of PHF (≤500 mg liter−1) at different pHs (5.8 to 6.8). In the absence of Cd, PHF stimulated yeast growth up to 10.4%. Cd inhibited growth up to 79.7%, induced intracellular accumulation of reactive oxygen species (ROS), and promoted plasma membrane disruption in a dose- and pH-dependent manner. The negative effects of Cd on growth were attenuated by the presence of PHF, and maximum growth recovery (53.8%) was obtained at the highest PHF concentration and pH. The coexposure to Cd and PHF decreased ROS accumulation up to 36.7% and membrane disruption up to 30.7% in a dose- and pH-dependent manner. Two mechanisms helped to explain the role of PHF in alleviating Cd toxicity to yeasts: PHF decreased Cd-induced oxidative stress and bound significant amounts of Cd in the extracellular medium, reducing its bioavailability to the cells.

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