scholarly journals Host–Guest Inclusion Complexes of Essential Oils with Strong Antibacterial and Antifungal Features in Beta-Cyclodextrin for Solid-State Pharmaceutical Applications

2021 ◽  
Vol 11 (14) ◽  
pp. 6597
Author(s):  
Aldo Arrais ◽  
Marta Manzoni ◽  
Alessia Cattaneo ◽  
Valentina Gianotti ◽  
Nadia Massa ◽  
...  
Keyword(s):  
Solid State ◽  
Essential Oil ◽  
Essential Oils ◽  
Inclusion Complexes ◽  
Production Costs ◽  
Good Tolerance ◽  
Actual Application ◽  
Beta Cyclodextrin ◽  
Ft Ir ◽  
Antibacterial And Antifungal

Essential oils are widely recognized as natural alternatives to pharmaceutical antibacterial and antifungal agents. With respect to standard pharmaceutics, the advantages of essential oils are their (i) low production costs, (ii) lack of chemical and biochemical drawbacks that are intrinsic to the synthetic production process and (iii) good tolerance by humans. On the other hand, the liquid nature of essential oils poses concerns about their actual application in different therapeutic issues regarding their persistence and the ability to control or prolong drug release. In this study, two essential oils from oregano and winter savory showing antibacterial and antifungal features were complexed in a solid state with beta-cyclodextrin. Host–guest inclusion complexes were characterized using FT-IR spectroscopy, ESI-MS and GC-MS techniques. Manyfold terpenic and non-terpenic components of the oils could be observed and unambiguously identified as being included inside the carbohydrate hosts. Many of them provided a specific biocidal action. Indeed, essential oil host–guest inclusion products were tested against two Candida species and an S. aureus reference strain, showing that the oils effectively maintained their liquid performances. Solid-state tablets of the essential oil inclusion complexes embedded in polyvinylpyrrolidone could be obtained. These results pave the way for the solid-state application of essential oils in antibacterial and antifungal pharmaceutical treatments.

scholarly journals Postharvest quality of essential oil treated roses

2017 ◽  
Vol 23 (2) ◽  
pp. 192 ◽  
Author(s):  
Guilherme Mariano Manfredini ◽  
Patrícia Duarte de Oliveira Paiva ◽  
Elka Fabiana Aparecida Almeida ◽  
Ângela Maria Pereira Do Nascimento ◽  
Thaís Silva Sales ◽  
...  
Keyword(s):  
Essential Oil ◽  
Essential Oils ◽  
Cold Storage ◽  
Production Costs ◽  
Postharvest Quality ◽  
Vase Life ◽  
Pot Life ◽  
Low Toxicity ◽  
Flower Quality ◽  
Cold Chamber

The loss of commercial quality during storage and transportation of roses is one of the factors that reflect on production costs, leading producers to preventively apply harmful chemicals, mainly to hamper Botrytis cinerea development and reduce further losses. An alternative to increase flower longevity without contaminating the environment with harmful chemicals is the use of natural products, such as essential oils, which have fungistatic and insecticide properties, as well as low toxicity. The objective of this study was to evaluate the effect of essential oils on the vase life of Rosa cv. Avalanche: 12 treatments were tested, resulting from the combination of 5 types of essential oils plus the control in two cold storage periods (2 to 6 days) at 1 °C, 90-95% RH. The essential oils tested were eucalyptus, cinnamon, lemongrass and peppermint (1%), clove (0.1%), plus a control with distilled water. Application was made by spraying the flower buds. After storage at low temperatures, the flower stems were kept in a room (16 °C, 70% RH) during 10 days for evaluation. Flower stems stored for 2 days in a cold chamber showed better means for darkening, turgor and bent neck, as well as a lower weight loss by the stems. The application of lemongrass essential oil at 1% caused burns on the petals, compromising quality and pot life. The essential oils of peppermint and eucalyptus allowed flower quality maintenance until the 10th day of evaluation. It is possible to conclude that post-harvest spraying with peppermint or eucalyptus essential oil at 1%, combined with cold storage for 2 days, provided greater longevity and quality for cv. Avalanche roses.

scholarly journals Antimicrobial Activity of Essential Oils and Solvent Extracts from Zieria species (Rutaceae)

2013 ◽  
Vol 8 (6) ◽  
pp. 1934578X1300800
Author(s):  
Nicholas J. Sadgrove ◽  
Graham L. Jones
Keyword(s):  
Antifungal Activity ◽  
Essential Oil ◽  
Essential Oils ◽  
Essential Oil Composition ◽  
Antibacterial And Antifungal Activity ◽  
Oil Composition ◽  
Pharmaceutical Development ◽  
Antibacterial And Antifungal ◽  
Broth Dilution ◽  
Nutraceutical Products

Essential oils were hydrodistilled from six Zieria species, including two previously not investigated: Z. floydii and Z. odorifera subsp. williamsii, and characterized using GC-MS. Additionally, solvent extracts of leaf material from five of these species were prepared using n-hexane, acetone and methanol as solvents, respectively. These solvent extracts were examined, along with essential oils, for antibacterial activity using micro titer plate broth dilution assays. Antifungal activity against pathogenic Trichophyton species responsible for dermal infections such as Tinea and Kangaroo Pox (uncommon), was examined using a similar method. Results of essential oil characterizations are relatively consistent with those previously reported. Interestingly, the essential oil composition of Z. floydii showed car-3-en-2-one at a concentration of 71%, similar to that observed in a previous study for Z. furfuracea and Z. granulata, thus complementing the observations of A.G. Floyd that Z. floydii is morphologically allied with these two species (CANB 598758). Antimicrobial assays demonstrated relatively high antibacterial and antifungal activity, using both essential oils and solvent extracts. This is particularly true for the n-hexane extract from Z. smithii. We therefore conclude that Zieria species may be a useful source for the development of antiseptic, cosmaceutical and/or topical nutraceutical products. In addition, they may well serve as a source of further novel, purified compounds providing scaffolds for pharmaceutical development in the future.

scholarly journals Amylose Inclusion Complexes as Emulsifiers for Garlic and Asafoetida Essential Oils for Mosquito Control

Insects ◽  
2019 ◽  
Vol 10 (10) ◽  
pp. 337 ◽  
Author(s):  
Ephantus J. Muturi ◽  
William T. Hay ◽  
Robert W. Behle ◽  
Gordon W. Selling
Keyword(s):  
Essential Oil ◽  
Essential Oils ◽  
Inclusion Complexes ◽  
Mosquito Control ◽  
Storage Period ◽  
High Sensitivity ◽  
Sodium Palmitate ◽  
Plant Essential Oils ◽  
Vector Management ◽  
High Volatility

Although the insecticidal properties of some plant essential oils are well-documented, their use in integrated pest and vector management is complicated by their high volatility, low thermal stability, high sensitivity to oxidation, and low solubility in water. We investigated the use of bio-based N-1-hexadecylammonium chloride and sodium palmitate amylose inclusion complexes as emulsifiers for two essential oils, garlic and asafoetida, known to be highly toxic to mosquito larvae. Four emulsions of each essential oil based on amylose hexadecylammonium chloride and amylose sodium palmitate inclusion complexes were evaluated for their toxicity against Aedes aegypti L. larvae relative to bulk essential oils. All emulsions were significantly more toxic than the bulk essential oil with the lethal dosage ratios ranging from 1.09–1.30 relative to bulk essential oil. Droplet numbers ranged from 1.11 × 109 to 9.55 × 109 per mL and did not change significantly after a 6-month storage period. These findings demonstrated that amylose inclusion complexes enhanced the toxicity of essential oils and could be used to develop new essential oil based larvicides for use in integrated vector management.

scholarly journals Inclusion complexes of cinnarizine with .BETA.-cyclodextrin in aqueous solution and in the solid state.

1984 ◽  
Vol 32 (10) ◽  
pp. 4179-4184 ◽  
Author(s):  
TADAKAZU TOKUMURA ◽  
HARUHISA UEDA ◽  
YUKI TSUSHIMA ◽  
MASAYOSHI KASAI ◽  
MASANORI KAYANO ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Solid State ◽  
Inclusion Complexes ◽  
Beta Cyclodextrin

Characterization of beta-cyclodextrin inclusion complexes containing an essential oil component

2016 ◽  
Vol 196 ◽  
pp. 968-975 ◽  
Author(s):  
Romina L. Abarca ◽  
Francisco J. Rodríguez ◽  
Abel Guarda ◽  
María J. Galotto ◽  
Julio E. Bruna
Keyword(s):  
Essential Oil ◽  
Inclusion Complexes ◽  
Cyclodextrin Inclusion Complexes ◽  
Beta Cyclodextrin ◽  
Cyclodextrin Inclusion

scholarly journals Antimicrobial activity of Hypericum annulatum moris and Hypericum elegans stephan ex willd. essential oils from Serbia

2013 ◽  
Vol 19 (1) ◽  
pp. 7-11
Author(s):  
Aleksandra Djordjevic ◽  
Jelena Lazarevic ◽  
Violeta Mitic ◽  
Radosav Palic ◽  
Gordana Stojanovic
Keyword(s):  
Antimicrobial Activity ◽  
Antifungal Activity ◽  
Essential Oil ◽  
Essential Oils ◽  
Antibacterial And Antifungal Activity ◽  
Significant Difference ◽  
Bacteria And Fungi ◽  
Antibacterial And Antifungal ◽  
Hypericum Species

The in vitro antimicrobial activity of Hypericum annulatum and Hypericum elegans essential oils was evaluated against a panel of standardized bacteria and fungi using broth microdilution assay. Both essential oils showed antimicrobial activity against all the tested microorganisms. Hypericum annulatum essential oil showed better antibacterial than antifungal activity, being more effective against Pseudomonas aeruginosa and Escherichia coli while H. elegans essential oil showed no significant difference between antibacterial and antifungal activity. Antimicrobial testing of ?-pinene, ?-pinene and ?-myrcene compounds was also performed. All the compounds were active against all the tested microorganisms, however, based on the MIC, MBC and MFC values, none of these compounds could be thought of as the main bearer of the oils? antimicrobial activity. This is the first report regarding the antimicrobial activity of the essential oils of the two Hypericum species.

scholarly journals Essential Oil Compositions, Antibacterial and Antifungal Activities of Nigerian Members of the Burseraceae: Boswellia dalzielii and Canarium schweinfurthii

2020 ◽  
Vol 15 (8) ◽  
pp. 1934578X2094694
Author(s):  
Moses S. Owolabi ◽  
Akintayo Ogundajo ◽  
Balogun Olaoye Solomon ◽  
Logunleko Olatunde ◽  
Noura S. Dosoky ◽  
...  
Keyword(s):  
Essential Oil ◽  
Essential Oils ◽  
Stem Bark ◽  
Biologically Active ◽  
Gas Chromatography Mass Spectrometry ◽  
Chemical Compositions ◽  
Antibacterial And Antifungal Activities ◽  
The Family ◽  
Leaf Essential Oil ◽  
Antibacterial And Antifungal

The Burseraceae is an important family of resin-producing trees and shrubs, which have yielded biologically active essential oils. Boswellia dalzielii and Canarium schweinfurthii are members of the family that are used in West African traditional medicine for a variety of ailments. The leaf essential oils of B. dalzielii have been obtained from 2 different locations in north-central Nigeria, while the leaf and stem bark essential oils of C. schweinfurthii have been obtained from 3 locations. The chemical compositions of the essential oils have been determined by gas chromatography-mass spectrometry and show wide variation, especially for the leaf essential oils. The leaf essential oils of B. dalzielii and C. schweinfurthii have been screened for antibacterial and antifungal activity; C. schweinfurthii leaf essential oil showed remarkable activity against Aspergillus niger with a minimum inhibitory concentration of 78.1 μg/mL.

scholarly journals The Composition and Antimicrobial Activities of Cyperus conglomeratus, Desmos chinensis var. lawii and Cyathocalyx zeylanicus Essential Oils

2012 ◽  
Vol 7 (5) ◽  
pp. 1934578X1200700 ◽  
Author(s):  
Abdulkhader Hisham ◽  
Koranappallil B. Rameshkumar ◽  
Neelam Sherwani ◽  
Salim Al-Saidi ◽  
Salma Al-Kindy
Keyword(s):  
Nmr Spectroscopy ◽  
Essential Oil ◽  
Essential Oils ◽  
Antimicrobial Activities ◽  
Moderate Activity ◽  
Benzyl Benzoate ◽  
Antibacterial And Antifungal Activities ◽  
Microbial Strains ◽  
Antibacterial And Antifungal ◽  
C Nmr

The essential oil compositions of the rhizomes of Cyperus conglomeratus (Cyperaceae) collected from Oman and the leaves of two Annonaceae plants, Desmos chinensis var. lawii and Cyathocalyx zeylanicus collected from India were studied by GC, GC-MS and 13C NMR spectroscopy. Twenty-six compounds, representing 84.4% of the oil were identified in C. conglomeratus, where eugenol (31.3%), α-cyperone (10.5%) and cyperotundone (8.4%) were the major compounds. Twelve compounds, constituting 100%, were identified in D. lawii oil, of which benzyl benzoate (58.7%), β-caryophyllene (23.2%), limonene (4.9%) and α-humulene (4.0%) were the major constituents. Thirty-two compounds, comprising 98.0%, were identified in C. zeylanicus oil, of which β-caryophyllene (21.6%), α-pinene (20.4%) and E-β-ocimene (11.8%) were the major components. The antibacterial and antifungal activities of the oils were tested against a panel of five bacterial and two fungal strains. The oils showed moderate activity against all the tested microbial strains. The minimum inhibitory concentrations of the oils were also determined.

scholarly journals Structural characterisation of starch based edible films with essential oil addition

2016 ◽  
Vol 10 (1) ◽  
pp. 53-57
Author(s):  
Danijela Z. Šuput ◽  
Vera L. Lazić ◽  
Lato L. Pezo ◽  
Biljana Lj. Lončar ◽  
Milica R. Nićetin ◽  
...  
Keyword(s):  
Essential Oil ◽  
Essential Oils ◽  
Room Temperature ◽  
Petri Dish ◽  
Black Pepper ◽  
Edible Films ◽  
Structural Characterisation ◽  
Black Cumin ◽  
Ft Ir ◽  
Ftir Spectrometer

Present study investigated structure of starch based edible films with essential oil addition. Films were obtained from water solutions containing gelatinized modified starch, polyol, guar-xantan gum modified mixture and essential oil by casting it on a Petri dish and evaporating at room temperature for 72h. Both, glycerol and guar-xantan modified mixture, had role to improve film flexibility and enable better film folding and handling. Two sample groups were obtained: starch based edible films with black cumin oil addition and starch based edible films with black pepper oil addition. Both essential oils were added in three different concentrations. Starch based edible film without essential oil addition was used as blank shot. Structural properties were determined by analyzing spectra obtained by FT-IR Spectrometer in the spectral range of 4000–400 cm−1 with a 4.0 cm−1 resolution. Software Omnic 8.1. and TQ Analyst were used to operate the FTIR spectrometer, collect and present all the data. Results pointed to quantitative law dependency between added amount of essential oils and spectra absorption values for both sample groups and FTIR spectra were used to calculate coefficient of correlation.

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