scholarly journals Injectable Hydrogels for Chronic Skin Wound Management: A Concise Review

Biomedicines ◽  
2021 ◽  
Vol 9 (5) ◽  
pp. 527
Author(s):  
Mazlan Zawani ◽  
Mh Busra Fauzi
Keyword(s):  
Chronic Wounds ◽  
Wound Care ◽  
Skin Wound ◽  
Wound Management ◽  
Diabetic Patients ◽  
Key Factors ◽  
Injectable Hydrogel ◽  
The Government ◽  
Chronic Skin ◽  
Care Costs

Diabetic foot ulcers (DFU) are a predominant impediment among diabetic patients, increasing morbidity and wound care costs. There are various strategies including using biomaterials have been explored for the management of DFU. This paper will review the injectable hydrogel application as the most studied polymer-based hydrogel based on published journals and articles. The main key factors that will be discussed in chronic wounds focusing on diabetic ulcers include the socioeconomic burden of chronic wounds, biomaterials implicated by the government for DFU management, commercial hydrogel product, mechanism of injectable hydrogel, the current study of novel injectable hydrogel and the future perspectives of injectable hydrogel for the management of DFU.

scholarly journals Prevention and therapy of acute and chronic wounds using NPWT devices during the COVID-19 pandemic, recommendation from The NPWT Working Group

2020 ◽  
Vol 7 (2) ◽  
Author(s):  
Tomasz Banasiewicz ◽  
Rolf Becker ◽  
Adam Bobkiewicz ◽  
Marco Fraccalvieri ◽  
Wojciech Francuzik ◽  
...  
Keyword(s):  
Wound Healing ◽  
Chronic Wounds ◽  
Hospital Admissions ◽  
Wound Care ◽  
Care Center ◽  
Management Strategies ◽  
Hospital Staff ◽  
Wound Management ◽  
Health Care Center ◽  
Single Use

Recent SARS-CoV-2 pandemic leading to a rapidly increasing number of hospitalizations enforced reevaluation of wound management strategies. The optimal treatment strategy for patients with chronic wounds and those recovering from emergency and urgent oncological surgery should aim to minimize the number of hospital admissions, as well as the number of surgical procedures and decrease the length of stay to disburden the hospital staff and to minimize viral infection risk. One of the potential solutions that could help to achieve these goals may be the extensive and early use of NPWT devices in the prevention of wound healing complications. Single-use NPWT devices are helpful in outpatient wound treatment and SSI prevention (ciNPWT) allowing to minimize in-person visits to the health care center while still providing the best possible wound-care. Stationary NPWT should be used in deep SSI and perioperative wound healing disorders as soon as possible. Patient’s education and telemedical support with visual wound healing monitoring and video conversations have the potential to minimize the number of unnecessary in-person visits in patients with wounds and therefore substantially increase the level of care.

scholarly journals Telemedicine for wound management

2012 ◽  
Vol 45 (02) ◽  
pp. 412-417 ◽  
Author(s):  
Ravi K. Chittoria
Keyword(s):  
Health Care ◽  
Chronic Wounds ◽  
Wound Care ◽  
Cost Effective ◽  
Skin Lesions ◽  
Wound Management ◽  
Care Practice ◽  
Telemedicine Technology ◽  
Store And Forward ◽  
Financial Burdens

ABSTRACTThe escalating physiological, psychological, social and financial burdens of wounds and wound care on patients, families and society demand the immediate attention of the health care sector. Many forces are affecting the changes in health care provision for patients with chronic wounds, including managed care, the limited number of wound care therapists, an increasingly ageing and disabled population, regulatory and malpractice issues, and compromised care. The physician is also faced with a number of difficult issues when caring for chronic wound patients because their conditions are time consuming and high risk, represent an unprofitable part of care practice and raise issues of liability. Telemedicine enhances communication with the surgical wound care specialist. Digital image for skin lesions is a safe, accurate and cost-effective referral pathway. The two basic modes of telemedicine applications, store and forward (asynchronous transfer) and real-time transmission (synchronous transfer, e.g. video conference), are utilized in the wound care setting. Telemedicine technology in the hands of an experienced physician can streamline management of a problem wound. Although there is always an element of anxiety related to technical change, the evolution of wound care telemedicine technology has demonstrated a predictable maturation process.

scholarly journals Evaluation of a Clinical Decision Support System in the Domain of Chronic Wound Management

2021 ◽  
Author(s):  
Stefan Vogel ◽  
Jendrik Richter ◽  
Stefanie Wache ◽  
Kerstin Pischek-Koch ◽  
Simone Auchter ◽  
...  
Keyword(s):  
Clinical Decision Support System ◽  
Chronic Wounds ◽  
Wound Care ◽  
Clinical Decision ◽  
Wound Management ◽  
Domain Experts ◽  
Nursing Science ◽  
It Systems ◽  
Chronic Wound Management ◽  
Software Prototype

The PosiThera project focuses on the management of chronic wounds, which is multi-professional and multi-disciplinary. For this context, a software prototype was developed in the project, which is intended to support medical and nursing staff with the assistance of artificial intelligence. In accordance with the user-centred design, national workshops were held at the beginning of the project with the involvement of domain experts in wound care in order to identify requirements and use cases of IT systems in wound care, with a focus on AI. In this study, the focus was on involving nursing and nursing science staff in testing the software prototype to gain insights into its functionality and usability. The overarching goal of the iterative testing and adaptation process is to further develop the prototype in a way that is close to care.

scholarly journals Modern wound care application in diabetic wound management

2017 ◽  
Vol 5 (2) ◽  
pp. 702
Author(s):  
. Rohmayanti ◽  
Estrin Handayani
Keyword(s):  
Diabetic Patient ◽  
Wound Care ◽  
Healing Process ◽  
Wound Complication ◽  
Wound Management ◽  
Management Approach ◽  
Wound Healing Process ◽  
Diabetic Patients ◽  
Diabetic Wound ◽  
Wound Size

Diabetes mellitus is a group of metabolic disease which facilitates diabetic wound foot. To prevent long diabetic wound complication and worse condition it is needed wound care for diabetic patient. Modern bandage has been used for recent wound care technique. The principles of modern wound care product are maintaining and watching over the humid environment of the wound to facilitate the wound healing process, maintaining liquid tissue deprivation and cell decease. This research was aimed to find out how modern wound bandage is applied to the diabetic patient and to find out the influence in healing wound phase. This research is qualitative research using phenomenology approach, 4 wound diabetic patients who were hospitalized for 2 weeks using modern wound care method in Magelang regency were participated. The participants were elected using purposive sampling method. Observation and interview were used to obtain data, data was analyzed using explanation building method. The results of this research have 4 topics which are wound examination, type of modern bandage, the way of wound care, and the influence toward the wound. Bates-Jensen Wound was used for the wound examination, the type of bandage used were hydrogel and wound ointment, TIME management approach was used in wound care, and the wound care influences the decreasing of wound size, wound proliferation and granulation. Modern bandage application of diabetic wound influences the decreasing of wound size, wound proliferation and granulation. Paramedic is suggested to use modern wound care method in diabetic wound management.

scholarly journals Hydrogel-Based Strategies to Advance Therapies for Chronic Skin Wounds

2019 ◽  
Vol 21 (1) ◽  
pp. 145-169 ◽  
Author(s):  
Lucília P. da Silva ◽  
Rui L. Reis ◽  
Vitor M. Correlo ◽  
Alexandra P. Marques
Keyword(s):  
Tissue Engineering ◽  
Chronic Wounds ◽  
Significant Risk ◽  
Skin Regeneration ◽  
Wound Management ◽  
Skin Wounds ◽  
Preclinical Models ◽  
Moist Environment ◽  
Chronic Skin ◽  
Bioactive Agents

Chronic skin wounds are the leading cause of nontraumatic foot amputations worldwide and present a significant risk of morbidity and mortality due to the lack of efficient therapies. The intrinsic characteristics of hydrogels allow them to benefit cutaneous healing essentially by supporting a moist environment. This property has long been explored in wound management to aid in autolytic debridement. However, chronic wounds require additional therapeutic features that can be provided by a combination of hydrogels with biochemical mediators or cells, promoting faster and better healing. We survey hydrogel-based approaches with potential to improve the healing of chronic wounds by reviewing their effects as observed in preclinical models. Topics covered include strategies to ablate infection and resolve inflammation, the delivery of bioactive agents to accelerate healing, and tissue engineering approaches for skin regeneration. The article concludes by considering the relevance of treating chronic skin wounds using hydrogel-based strategies.

scholarly journals Bioactive Antimicrobial Peptides as Therapeutic Agents for Infected Diabetic Foot Ulcers

Biomolecules ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 1894
Author(s):  
Jessica Da Silva ◽  
Ermelindo C. Leal ◽  
Eugénia Carvalho
Keyword(s):  
Wound Healing ◽  
Antimicrobial Peptides ◽  
Broad Spectrum ◽  
Diabetic Foot ◽  
Molecular Mechanisms ◽  
Antimicrobial Agents ◽  
Chronic Wounds ◽  
Foot Ulcer ◽  
Wound Management ◽  
Diabetic Patients

Diabetic foot ulcer (DFU) is a devastating complication, affecting around 15% of diabetic patients and representing a leading cause of non-traumatic amputations. Notably, the risk of mixed bacterial–fungal infection is elevated and highly associated with wound necrosis and poor clinical outcomes. However, it is often underestimated in the literature. Therefore, polymicrobial infection control must be considered for effective management of DFU. It is noteworthy that antimicrobial resistance is constantly rising overtime, therefore increasing the need for new alternatives to antibiotics and antifungals. Antimicrobial peptides (AMPs) are endogenous peptides that are naturally abundant in several organisms, such as bacteria, amphibians and mammals, particularly in the skin. These molecules have shown broad-spectrum antimicrobial activity and some of them even have wound-healing activity, establishing themselves as ideal candidates for treating multi-kingdom infected wounds. Furthermore, the role of AMPs with antifungal activity in wound management is poorly described and deserves further investigation in association with antibacterial agents, such as antibiotics and AMPs with antibacterial activity, or alternatively the application of broad-spectrum antimicrobial agents that target both aerobic and anaerobic bacteria, as well as fungi. Accordingly, the aim of this review is to unravel the molecular mechanisms by which AMPs achieve their dual antimicrobial and wound-healing properties, and to discuss how these are currently being applied as promising therapies against polymicrobial-infected chronic wounds such as DFUs.

Quercetin and its Natural Sources in Wound Healing Management

2019 ◽  
Vol 26 (31) ◽  
pp. 5825-5848 ◽  
Author(s):  
Nicoletta Polera ◽  
Mariateresa Badolato ◽  
Filomena Perri ◽  
Gabriele Carullo ◽  
Francesca Aiello
Keyword(s):  
Wound Healing ◽  
Wound Repair ◽  
Chronic Wounds ◽  
Wound Care ◽  
Biological Activities ◽  
Healing Process ◽  
Wound Management ◽  
Wound Healing Process ◽  
Impaired Wound Healing ◽  
Care Research

Giving a glance to the report of Wound Care Market by Product updated in 2017, we can see that wound care market is expected to reach USD 22.01 billion by 2022 from USD 18.35 billion at a CAGR of 3.7%. Numerous factors are driving the growth of this market, including the increasing prevalence of chronic wounds and acute wounds, increasing aged population, rising R&D activities and advancement in the field of wound care research. Advanced wound management products are accounted for the largest market share in 2017. These evidences mean that the wound care research represents a Clinical Emergency other than an interesting Marketing tool. Drug therapies so far fight efficaciously with the opportunistic pathologies derived from chronic wounds, although an unsolved challenge is still finding a useful remedy to correct the impaired wound healing process and overcome the chronic wound state, to avoid bacterial rising and severe pain. Traditional medicinal plants have been widely used in the management of wounds and different plant extracts have been evaluated for their wound healing properties through both in vitro and in vivo studies. Their phytochemical components in particular quercetin, contribute to their remedial properties in wound repair. Quercetin has important biological activities related to the improvement of the wound healing process. The present review discusses and focuses on the latest findings of the wound healing properties of quercetin, alone or as a part of plant extract, and its role as a new frontier in wound repair.

scholarly journals Fully automatic wound segmentation with deep convolutional neural networks

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Chuanbo Wang ◽  
D. M. Anisuzzaman ◽  
Victor Williamson ◽  
Mrinal Kanti Dhar ◽  
Behrouz Rostami ◽  
...  
Keyword(s):  
Neural Networks ◽  
Deep Learning ◽  
Chronic Wounds ◽  
Wound Care ◽  
Natural Images ◽  
Wound Management ◽  
Learning Models ◽  
Deep Convolutional Neural Networks ◽  
Care Protocol ◽  
Fully Automatic

AbstractAcute and chronic wounds have varying etiologies and are an economic burden to healthcare systems around the world. The advanced wound care market is expected to exceed $22 billion by 2024. Wound care professionals rely heavily on images and image documentation for proper diagnosis and treatment. Unfortunately lack of expertise can lead to improper diagnosis of wound etiology and inaccurate wound management and documentation. Fully automatic segmentation of wound areas in natural images is an important part of the diagnosis and care protocol since it is crucial to measure the area of the wound and provide quantitative parameters in the treatment. Various deep learning models have gained success in image analysis including semantic segmentation. This manuscript proposes a novel convolutional framework based on MobileNetV2 and connected component labelling to segment wound regions from natural images. The advantage of this model is its lightweight and less compute-intensive architecture. The performance is not compromised and is comparable to deeper neural networks. We build an annotated wound image dataset consisting of 1109 foot ulcer images from 889 patients to train and test the deep learning models. We demonstrate the effectiveness and mobility of our method by conducting comprehensive experiments and analyses on various segmentation neural networks. The full implementation is available at https://github.com/uwm-bigdata/wound-segmentation.

New tools in wound care to support evidence-based best practice

2020 ◽  
Vol 25 (3) ◽  
pp. S26-S29
Author(s):  
Melanie Lumbers
Keyword(s):  
Wound Healing ◽  
Best Practice ◽  
Chronic Wounds ◽  
Wound Care ◽  
Wound Management ◽  
Evidence Based ◽  
Ageing Population ◽  
Positive Outcomes ◽  
Technological Advances ◽  
Management Concepts

Throughout history, various wound healing and management concepts have been recorded, with some approaches such as honey, silver and larvae still in use and others such as blood-letting completely dismissed. In more recent times, dressing products have begun evolving, moving on from basic first-aid supplies to products that support positive healing by addressing the needs of the wound bed and considering underlying factors that impact healing. With an ageing population, the incidence of chronic wounds is predicted to rise, and chronic wounds can negatively impact the lives of patients physically, emotionally and financially. Clinicians continue to explore and review new approaches surrounding the management of wounds, as it is imperative that clinicians use technological advances in wound management alongside established gold standard evidence-based practice to achieve positive outcomes for patients experiencing delayed or challenging wound healing.

A photometric stereo approach for chronic wound measurement

Sensor Review ◽  
2015 ◽  
Vol 35 (4) ◽  
pp. 419-424 ◽  
Author(s):  
Jiuai Sun ◽  
Xiaoping Xu ◽  
Abdul Rehman Farooq ◽  
Lyndon Neal Smith ◽  
Melvyn Lionel Smith
Keyword(s):  
Chronic Wounds ◽  
Wound Care ◽  
Skin Surface ◽  
Photometric Stereo ◽  
Wound Management ◽  
Clinical Settings ◽  
Content Type ◽  
Good Potential ◽  
Review State ◽  
Color Texture

Purpose – This paper aims to review state of the art of techniques for dimensioning chronic wounds, and validate the possibilities of employing a new proposed optical imaging approach for general task of wound assessment. Design/methodology/approach – Current techniques used for quantifying wound surface are reviewed and evaluated from various perspectives to exam their usability in wound care clinical settings. A photometric stereo (PS) approach will be identified and verified to work as an alternative solution to better satisfy practical requirements on quantifying the dimension of real and mocked wounds. Findings – Both contact and contactless approaches provide some useful functions for wound management; however, new imaging modalities are still required for achieving good portability, affordability and applicability in assisting decision-making in clinical settings. The PS approach can work as a potential solution to provide these functionalities as well as dense geometrical and color texture information of measured areas. The experiments demonstrate that the new approach is able to conveniently produce comparable results to those from latest stereo vision-based techniques. Research limitations/implications – This work proposed and initially verified the potential of PS technique for the task of wound measurement. Substantial improvements on the prototype and more clinical trials are still required to validate the new technique before it is accepted as a tool for practical wound measurement. Originality/value – This new PS approach has good potential to reliably measure the dimension of wounds as well as recover their color texture which could contain additional valuable information for predicting a healing procedure for those wound occurring deeper underneath the skin surface.

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