scholarly journals Cross-National Variations in COVID-19 Mortality: The Role of Diet, Obesity and Depression

Diseases ◽  
2021 ◽  
Vol 9 (2) ◽  
pp. 36
Author(s):  
Ravi Philip Rajkumar

Background: The COVID-19 pandemic has been characterized by wide variations in mortality across nations. Some of this variability may be explained by medical comorbidities such as obesity and depression, both of which are strongly correlated with dietary practices such as levels of sugar and seafood consumption. Methods: COVID-19 mortality indices for 156 countries were obtained from the Johns Hopkins University’s data aggregator. Correlations between these variables and (a) per capita consumption of sugar and seafood, and (b) country-wise prevalence of depression and obesity were examined. Results: Sugar consumption (r = 0.51, p < 0.001) and prevalence of obesity (r = 0.66, p < 0.001) and depression (r = 0.56, p < 0.001) were positively correlated with crude mortality rates, while seafood consumption was negatively correlated with the infection fatality rate (r = −0.28, p = 0.015). These effects were significant even after correcting for potential confounders. The associations with depression and obesity remained significant upon multivariate regression. Conclusions: Both obesity and depression, which are associated with inflammatory dysregulation, may be related to cross-national variations in COVID-19 mortality, while seafood consumption may be protective. These findings have implications in terms of protecting vulnerable individuals during the current pandemic.

2017 ◽  
Vol 29 (4) ◽  
pp. 796-812 ◽  
Author(s):  
Osmud Rahman ◽  
Benjamin C.M. Fung ◽  
Zhimin Chen ◽  
Xiang Gao

Purpose The purpose of this paper is to investigate and identify the salient effects of apparel evaluativ1e cues in order to enrich our understanding of consumer preferences and behaviour in two different socio-cultural contexts – Canada from the west and China of the east. Design/methodology/approach Online and paper questionnaires were used to collect data from Canada and China. Based on the prior research, 14 hypotheses were developed, and SPSS statistical analyses were used for this study. Findings According to the findings, Canadian and Chinese participants used price as an indicator of product quality and/or monetary sacrifice. Overall, the consumers from both countries were more concerned about the garment fit and style than brand name and country of origin. It is imperative for fashion practitioners to prioritise their resources and focus more on product research/design and prototype development. Fit, comfort and fabric were strongly correlated except in the “fit and comfort” of the Canadian sample. In addition, durability, ease of care and wardrobe coordination play a relatively less significant clothing evaluative role than many other product cues. Originality/value There are relatively few research studies have focussed on apparel consumer behaviour, and the salient impact of product-evaluative cues – particularly from a cross-national perspective. This study covers a wide array of important evaluative cues, and provides meaningful insights to both fashion academicians and practitioners. This is one of the few studies provide an in-depth and comprehensive report on the role and effects of apparel product cues.


2020 ◽  
Vol 28 ◽  
Author(s):  
Seyed Mohammad Nabavi ◽  
Kasi Pandima Devi ◽  
Sethuraman Sathya ◽  
Ana Sanches-Silva ◽  
Listos Joanna ◽  
...  

: Obesity is a major health concern for a growing fraction of the population, with the prevalence of obesity and its related metabolic disorders not being fully understood. Over the last decade, many attempts have been undertaken to understand the mechanisms at the basis of this condition, in which the accumulation of fat occurring in adipose tissue, leads to the pathogenesis of obesity related disorders. Among the most recent studies, those on Peroxisome Proliferator Activated Receptors (PPARs) revealed that these nuclear receptor proteins acting as transcription factors, among others, regulate the expression of genes involved in energy, lipid, and glucose metabolisms, and chronic inflammation. The three different isotypes of PPARs, with different tissue expression and ligand binding specificity, exert similar or overlapping functions directly or indirectly linked to obesity. In this study, we reviewed the available scientific reports concerning the PPARs structure and functions, especially in obesity, considering both natural and synthetic ligands and their role in the therapy of obesity and obesity-associated disorders. In the whole, the collected data show that there are both natural and synthetic compounds that show beneficial promising activity as PPAR agonists in chronic diseases related to obesity.


2016 ◽  
Vol 33 (S1) ◽  
pp. S307-S307
Author(s):  
M. Manea ◽  
B. Savu

IntroductionIt is well known that certain personality traits are more linked to drug abuse than others. Psychiatrists are more likely to emphasize the importance of impulsivity in the connection with substance disorders but in the following study we found an important percentage of patients that have a substance abuse were linked to anxiety through impulsiveness as a personality trait.ObjectivesMost youths admitted for a substance abuse are highly impulsive. Our quest was to differentiate what component of impulsivity was more frequently linked to a substance use disorder.MethodsIn the study were included 50 patients admitted in the 3rd Psychiatric Clinic, Substance Dependences Department, Cluj-Napoca. For the identification of the drug abused we used the multitest screening kit in correlation with the results from the Forensic Medicine Institute of Cluj-Napoca. Each patient completed the Barratt Impulsivity Scale and the Swedish Universities Scales of Personality.ResultsHigh scores on BIS-11 strongly correlated with attentional impulsiveness (Pearson's r correlation = .838) which means high inattention and cognitive instability this being linked with anxiety disorders. Cognitive Instability was correlated with Psychic Trait Anxiety (r = 0.29) and Motor Impulsiveness with Somatic Trait Anxiety (r = 0.3). Normal 0 false false false EN-US X-NONE X-NONE.ConclusionsThe underrecognized anxiety disorders in young adults whom are admitted for an addictive disorder prefrontal cortex is known to be the source of both impulsivity and could be linked to anxiety as well (valence asymmetry hypothesis). Normal 0 false false false EN-US X-NONE X-NONE.Disclosure of interestThe authors have not supplied their declaration of competing interest.


2021 ◽  
pp. 026732312110121
Author(s):  
Montse Bonet ◽  
David Fernández-Quijada

This article aims to study how private European radio is becoming commercially international through the expansion of radio brands beyond their national market. It is the first ever analysis of the expansion strategies of radio groups across Europe, including their footprint in each market in which they operate, from the political economy of cultural industries. The article maps the main radio groups in Europe, analyses cross-national champions in depth and establishes three main types. This study shows that, thanks to the possibilities of a deregulated market, strengthening the role of the brand and the format, and the agreements with other groups, broadcasting radio has overcome the obstacles that, historically, hindered its cross-border expansion.


Author(s):  
Zuzanna Brzozowska ◽  
Eva Beaujouan

AbstractThe use of fertility intention questions to study individual childbearing behaviour has developed rapidly in recent decades. In Europe, the Generations and Gender Surveys are the main sources of cross-national data on fertility intentions and their realisation. This study investigates how an inconsistent implementation of a question about wanting a child now affects the cross-country comparability of intentions to have a child within the next three years and their realisation. We conduct our analysis separately for women and men at prime and late reproductive ages in Austria, France, Italy and Poland. The results show that the overall share of respondents intending to have a child at some point in their life is similar in all four analysed countries. However, once the time horizon and the degree of certainty of fertility intentions are included, substantial cross-country differences appear, particularly in terms of proceptive behaviour and, consequently, the realisation of fertility intentions. We conclude that the inconsistent questionnaire adaptation makes it very difficult to assess the role of country context in the realisation of childbearing intentions.


2021 ◽  
Vol 27 (4) ◽  
pp. 100872
Author(s):  
Pedro López-Sáez ◽  
Jorge Cruz-González ◽  
Jose Emilio Navas-López ◽  
María del Mar Perona-Alfageme

1995 ◽  
Vol 46 (5) ◽  
pp. 1027 ◽  
Author(s):  
FP Smith ◽  
PS Cocks ◽  
MA Ewing

Cluster clover is a widely distributed and ecologically successful introduced legume in southern Australia. In an attempt to understand the role of genetic variation in this success, morphological and physiological traits were measured in 94 accessions from southern Australia and 6 from the Mediterranean basin. Flowering time ranged from 105 to 185 days after sowing, but was not strongly correlated with annual rainfall or length of growing season at the site of collection. Variation in other traits partitioned the populations into two morphs which, apart from flowering time and leaf marker, were largely homogeneous. The morphs differed significantly in floret number per inflorescence (22 v. 32-37) and seed mass (379 8g v. 523 8g), had different growth habits and strong within-morph associations between leaf markers and stipule and petal coloration. The morphs differed in their distributions within southern Australia and the pattern of distribution was related to summer maximum temperatures, winter minimum temperatures and spring rainfall. These results demonstrate that genetic variation has been important to the success of cluster clover and suggests that the variation is organized. The pattern of variation observed and its relationship to ecogeography is consistent with findings for other highly inbreeding species. A map of the species distribution in Western Australia is presented.


2021 ◽  
Vol 12 (8) ◽  
Author(s):  
David Della-Morte ◽  
Francesca Pacifici ◽  
Camillo Ricordi ◽  
Renato Massoud ◽  
Valentina Rovella ◽  
...  

AbstractThe pathophysiology of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and especially of its complications is still not fully understood. In fact, a very high number of patients with COVID-19 die because of thromboembolic causes. A role of plasminogen, as precursor of fibrinolysis, has been hypothesized. In this study, we aimed to investigate the association between plasminogen levels and COVID-19-related outcomes in a population of 55 infected Caucasian patients (mean age: 69.8 ± 14.3, 41.8% female). Low levels of plasminogen were significantly associated with inflammatory markers (CRP, PCT, and IL-6), markers of coagulation (D-dimer, INR, and APTT), and markers of organ dysfunctions (high fasting blood glucose and decrease in the glomerular filtration rate). A multidimensional analysis model, including the correlation of the expression of coagulation with inflammatory parameters, indicated that plasminogen tended to cluster together with IL-6, hence suggesting a common pathway of activation during disease’s complication. Moreover, low levels of plasminogen strongly correlated with mortality in COVID-19 patients even after multiple adjustments for presence of confounding. These data suggest that plasminogen may play a pivotal role in controlling the complex mechanisms beyond the COVID-19 complications, and may be useful both as biomarker for prognosis and for therapeutic target against this extremely aggressive infection.


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