scholarly journals How the Heart Was Involved in COVID-19 during the First Pandemic Phase: A Review

Epidemiologia ◽  
2021 ◽  
Vol 2 (1) ◽  
pp. 124-139
Author(s):  
Andrea Canalella ◽  
Ermanno Vitale ◽  
Francesca Vella ◽  
Paola Senia ◽  
Emanuele Cannizzaro ◽  
...  
Keyword(s):  
Public Health ◽  
Diabetes Mellitus ◽  
Scientific Community ◽  
Respiratory Virus ◽  
Clinical Manifestations ◽  
Hubei Province ◽  
Public Health Emergency ◽  
Converting Enzyme ◽  
Pathophysiological Mechanisms ◽  
Cardiovascular Involvement

Coronavirus disease (COVID-19) was first observed in Wuhan, Hubei Province (China) in December 2019, resulting in an acute respiratory syndrome. Only later was COVID-19 considered a public health emergency of international concern and, on 11 March 2020, the WHO classified it as pandemic. Despite being a respiratory virus, the clinical manifestations are also characterized by cardiological involvement, especially in patients suffering from previous comorbidities such as hypertension and diabetes mellitus, its complications being potentially serious or fatal. Despite the efforts made by the scientific community to identify pathophysiological mechanisms, they still remain unclear. A fundamental role is played by the angiotensin 2 converting enzyme, known for its effects at the cardiovascular level and for its involvement in COVID-19 pathogenesis. The goal of this paper was to highlight the mechanisms and knowledge related to cardiovascular involvement during the first pandemic phase, as well as to emphasize the main cardiological complications in infected patients.

scholarly journals COVID-19 Pandemic: A Global Disaster

2021 ◽  
Vol 1 (1) ◽  
pp. 7-8
Author(s):  
Solomon Arigwe Joseph ◽  
Abuhuraira Ado Musa ◽  
Faisal Muhammad ◽  
Tijjani Muhammad Ahmad
Keyword(s):  
Public Health ◽  
World Health Organization ◽  
Signs And Symptoms ◽  
Viral Disease ◽  
Hubei Province ◽  
Public Health Emergency ◽  
World Health ◽  
Novel Coronavirus ◽  
Health Organization

People began to become ill in late December 2019 in Wuhan, Hubei Province, China, and the illness was revealed to be a kind of pneumonia with unusual signs and symptoms. It was eventually discovered as a novel coronavirus, a virus that causes widespread sickness in animals and birds. World Health Organization (WHO) named this new viral disease coronavirus disease 2019 (COVID-19) and declared a Public Health Emergency of International Concern in January 2020.

scholarly journals Is there an impact of the COVID-19 pandemic on male fertility? The ACE2 connection

2020 ◽  
Vol 318 (6) ◽  
pp. E878-E880 ◽  
Author(s):  
Johnny S. Younis ◽  
Zaid Abassi ◽  
Karl Skorecki
Keyword(s):  
Public Health ◽  
Severe Acute Respiratory Syndrome ◽  
Angiotensin Converting Enzyme ◽  
Reproductive System ◽  
Male Fertility ◽  
Time Course ◽  
Public Health Emergency ◽  
Converting Enzyme ◽  
Angiotensin Converting Enzyme 2 ◽  
Main Host

The viral pandemic of the coronavirus disease 2019 (COVID-19), generated by a novel mutated severe acute respiratory syndrome coronavirus (SARS-CoV-2), has become a serious worldwide public health emergency, evolving exponentially. While the main organ targeted in this disease is the lungs, other vital organs, such as the heart and kidney, may be implicated. The main host receptor of the SARS-CoV-2 is angiotensin converting enzyme 2 (ACE2), a major component of the renin-angiotensin-aldosterone system (RAAS). The ACE2 is also involved in testicular male regulation of steroidogenesis and spermatogenesis. As the SARS-CoV-2 may have the potential to infect the testis via ACE2 and adversely affect male reproductive system, it is essential to commence with targeted studies to learn from the current pandemic, with the possibility of preemptive intervention, depending on the findings and time course of the continuing pandemic.

scholarly journals Conducting COVID-19-Related Research in Jordan: Are We Ready?

2020 ◽  
pp. 1-25
Author(s):  
Balqis Ikhmais ◽  
Alaa M. Hammad ◽  
Waleed Qirim ◽  
Osama H. Abusara ◽  
Jonathan Ling
Keyword(s):  
Public Health ◽  
Factor Analysis ◽  
Scientific Community ◽  
Factor Model ◽  
Five Factor Model ◽  
Public Health Emergency ◽  
Parallel Analysis ◽  
Suitable Model ◽  
Related Research ◽  
Bartlett’S Test

Abstract The Coronavirus Disease-2019 (COVID-19) pandemic is a public health emergency of international concern. This pandemic poses a challenge to research and scientific community. In this study, we developed and tested content reliability and content validity of a questionnaire designed for evaluating the readiness and willingness of researchers to participate in virology research in Jordan. The survey was hosted on an online platform, and the link was emailed. A total of 332 participants from universities across Jordan completed the survey. For factor analysis, Kaiser-Meyer-Olkin value (KMO) and Bartlett’s Test of Sphericity were conducted. Furthermore, exploratory factor analysis (EFA) with parallel analysis and scree plots were conducted to evaluate the most suitable model for the data. The result of the EFA suggested a five-factor model would fit the survey. Data showed that the lowest means were for researchers’ readiness to conduct virology research and readiness for virology research with means of 2.07 and 2.95, respectively. Moreover, years of experience and specialty had a significant effect on the readiness and willingness of virology research in Jordan. In conclusion, readiness for research and researchers should be addressed and authorities should pay attention to these shortcomings in virology research.

Kajian Terkini CoronaVirus Disease 2019 (COVID-19)

2020 ◽  
Vol 1 (1) ◽  
Author(s):  
Chicy Widya Morfi
Keyword(s):  
Public Health ◽  
Upper Airway ◽  
Hubei Province ◽  
Public Health Emergency ◽  
Lower Airway ◽  
Rt Pcr ◽  
Microbiological Method ◽  
The Public

The COVID-19 outbreak in Wuhan, Hubei Province, China, caused by a newly known coronavirus strain, SARS-CoV-2, up to March 3th, 2020, has caused 90.870 confirmed cases to be reported from 72 countries (including Indonesia) with 3.112 deaths (CFR 3,4%). Upper airway swab and lower airway aspirate specimens from suspected patients are required for examination by the RT-PCR microbiological method for establishing COVID-19. There are no specific antivirals for the management of COVID-19. On January, 30th, 2020 WHO has established Covid-19 as the Public Health Emergency of International Concern (PHEIC), but the increase in the number of cases is fast enough so that on March,11th 2020, WHO has established Covid-19 as a pandemic.

scholarly journals Uncontrolled diabetes mellitus: A risk factor for post COVID fibrosis

2021 ◽  
Vol 91 (1) ◽  
Author(s):  
Parul Mrigpuri ◽  
Sonal Sonal ◽  
Sonam Spalgais ◽  
Nitin Goel ◽  
Balakrishnan Menon ◽  
...  
Keyword(s):  
Public Health ◽  
Diabetes Mellitus ◽  
Risk Factor ◽  
Virus Disease ◽  
Public Health Emergency ◽  
World Health ◽  
Uncontrolled Diabetes ◽  
The World ◽  
Health Organization ◽  
Short Time

Dear Editor, The Corona virus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in the Wuhan province of china in December 2019. COVID-19 spread to the world in a short time and was declared as public health emergency of international concern by World Health Organization...

scholarly journals Prevalence of co-morbidities in hospitalized patients with COVID-19 in a COVID dedicated hospital

2021 ◽  
Vol 8 (11) ◽  
pp. 5293
Author(s):  
Kirti Vinayak Kinge ◽  
Smita Santosh Chavan ◽  
Balkrishna Adsul ◽  
Maharudra Kumbhar
Keyword(s):  
Public Health ◽  
Diabetes Mellitus ◽  
Clinical Outcome ◽  
Sampling Technique ◽  
Ethics Committee ◽  
Public Health Emergency ◽  
The Other ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Institutional Ethics

Background: A novel corona virus causing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection become a public health emergency of international concern. The infection has increased and caused pandemic. Underlying co-morbidities may worsen the clinical outcome. So, more attention is to be given to COVID patients with co-morbidities. Few studies have been conducted on the prevalence of predominant chronic diseases with COVID-19. Taking into consideration the above factors, a study has been undertaken to assess the prevalence of co-morbidities in a COVID dedicated hospital.Methods: A centre based retrospective study was carried out at a COVID dedicated hospital, Mumbai. All admitted patients of COVID 19 in a COVID dedicated hospital, Mumbai were selected in 4 and half months (19th March 2020 to 31st July 2020) by universal sampling technique. Patients above 20 years were included in the study and patients below 20 years were excluded from the study. Ethics Committee approval taken from an institutional ethics committee.Results: All 6072 patients who were above 20 years were included in the study. Mean age was 48 years and 67.7% were male. The prevalence of various co-morbidities was 25% for hypertension, 22.3% for diabetes mellitus, 5.2% for chronic kidney disease, 1.7% for chronic obstructive pulmonary disease, 0.9% for cerebrovascular disease and 0.3% for one or the other malignancy.Conclusions: It has been concluded that various co-morbidities are present in patients with COVID-19 which may worsen the clinical outcome. So, more attention is to be given to COVID patients with co-morbidities.

scholarly journals Diabetes and covid-19: more than the sum of two morbidities

2020 ◽  
Vol 54 ◽  
pp. 1-6 ◽  
Author(s):  
Bianca De Almeida Pititto ◽  
Sandra Roberta G. Ferreira
Keyword(s):  
Public Health ◽  
Diabetes Mellitus ◽  
Chronic Diseases ◽  
Epidemiological Data ◽  
Public Health Emergency ◽  
Biological Plausibility ◽  
Explanatory Hypothesis ◽  
High Prevalence ◽  
Future Challenges

The coronavirus disease 2019 (covid-19) pandemic has caused a public health emergency worldwide. Risk, severity and mortality of the disease have been associated with non-communicable chronic diseases, such as diabetes mellitus. Accumulated evidence has caused great concern in countries with high prevalence of this morbidity, such as Brazil. This text shows the picture of diabetes in Brazil, followed by epidemiological data and explanatory hypothesis for the association between diabetes and covid-19. We emphasized how the burden of these two morbidities in a middleincome country has aggravated this pandemic scenario. The comprehension of this association and biological plausibility may help face this pandemic and future challenges.

scholarly journals Coronavirus Disease 19 and Severe Acute Respiratory Syndrome Coronavirus 2: To More Efficient Control

2020 ◽  
Vol 1 (3) ◽  
Author(s):  
Otmane El Brini
Keyword(s):  
Public Health ◽  
Severe Acute Respiratory Syndrome ◽  
Angiotensin Converting Enzyme ◽  
Host Defense ◽  
Essential Elements ◽  
Public Health Emergency ◽  
Converting Enzyme ◽  
Angiotensin Converting Enzyme 2 ◽  
The Social ◽  
Efficient Control

The coronavirus disease 19 (COVID-19) is a viral infection caused by a new coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It is considered as a public health emergency of international concern. The only available way, apparently effective, to control this pandemic is the social distancing. However, other possible aspects of infection control may be mentioned. In this review, we highlight certain peculiarities linked to the nature of the virus and its angiotensin converting enzyme 2 receptor, the host defense and the final clinical manifestation of the infection that could be essential elements in strengthening the effectiveness of COVID-19 pandemic control efforts.

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