scholarly journals A Revisit to the Formation and Mitigation of 3-Chloropropane-1,2-Diol in Palm Oil Production

Foods ◽  
2020 ◽  
Vol 9 (12) ◽  
pp. 1769
Author(s):  
Farrah Aida Arris ◽  
Vincent Tiang Soon Thai ◽  
Wan Nabilah Manan ◽  
Mohd Shaiful Sajab
Keyword(s):  
Vegetable Oils ◽  
Palm Oil ◽  
Review Paper ◽  
Daily Intake ◽  
Organic Chemical ◽  
Food Contaminants ◽  
Potential Health ◽  
Food Contaminant ◽  
Oral Consumption ◽  
Different Types

Process-based contaminants in food—particularly in vegetable oils—have been a topic of interest due to their potential health risk on humans. Oral consumption above the tolerable daily intake might result in health risks. Therefore, it is critical to correctly address the food contaminant issues with a proper mitigation plan, in order to reduce and subsequently remove the occurrence of the contaminant. 3-monochloropropane-1,3-diol (3-MCPD), an organic chemical compound, is one of the heat- and process-induced food contaminants, belonging to a group called chloropropanols. This review paper discusses the occurrence of the 3-MCPD food contaminant in different types of vegetable oils, possible 3-MCPD formation routes, and also methods of reduction or removal of 3-MCPD in its free and bound esterified forms in vegetable oils, mostly in palm oil due to its highest 3-MCPD content.

scholarly journals Elucidating how two different types of bleaching earths widely used in vegetable oils industry remove carotenes from palm oil: Equilibrium, kinetics and thermodynamic parameters

2019 ◽  
Vol 121 ◽  
pp. 785-797 ◽  
Author(s):  
Erislene S. Almeida ◽  
Ariane Cristina Boechie Carvalho ◽  
Isabela Oliveira de Souza Soares ◽  
Leonardo Fonseca Valadares ◽  
Andressa Regina Vasques Mendonça ◽  
...  
Keyword(s):  
Thermodynamic Parameters ◽  
Vegetable Oils ◽  
Palm Oil ◽  
Different Types ◽  
Kinetics And Thermodynamic

scholarly journals Palm oil and threats to a critically important food source

2017 ◽  
Vol 1 ◽  
pp. 239784731769984 ◽  
Author(s):  
Roger Clemens ◽  
A Wallace Hayes ◽  
Kalyana Sundram ◽  
Peter Pressman
Keyword(s):  
Fatty Acid ◽  
Palmitic Acid ◽  
Palm Oil ◽  
Edible Oils ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Food Contaminants ◽  
Potential Health ◽  
Toxicological Effects ◽  
History Of

The oil palm, an ancient tropical tree species that originated in West Africa, has a history of centuries-long use both as a food and a medicine. Based on its higher saturated fatty acid composition, primarily palmitic acid, concerns have been flagged about its nutritional attributes. Elevation of low-density lipoprotein cholesterol effects of the associated palmitic acid is far less profound than animal sources of this fatty acid and is linked with multiple health benefits. Recently, the European Food Safety Authority raised issues about potential health risks of the chloropropanols, heat- or acid-induced food contaminants created during the refining of all edible oils, and some hydrolyzed proteins. Despite the fact that the levels of 3-monochloropropane1,2 diol and its glycidyl esters are generally <800 ppb and without demonstrated toxicological effects in humans, the chloropropanols in palm oil appear to be a lightning rod for global criticism. The toxicological data are reviewed and evaluated, and an approach for mitigation of the emerging challenge is suggested.

Potential Uses of Vinegar as a Medicine and Related in vivo Mechanisms

2016 ◽  
Vol 86 (3-4) ◽  
pp. 127-151 ◽  
Author(s):  
Zeshan Ali ◽  
Zhenbin Wang ◽  
Rai Muhammad Amir ◽  
Shoaib Younas ◽  
Asif Wali ◽  
...  
Keyword(s):  
Chemical Structure ◽  
Review Paper ◽  
Heart Diseases ◽  
Folk Medicine ◽  
Active Role ◽  
Current Review ◽  
Different Types ◽  
Positive Effect

While the use of vinegar to fi ght against infections and other crucial conditions dates back to Hippocrates, recent research has found that vinegar consumption has a positive effect on biomarkers for diabetes, cancer, and heart diseases. Different types of vinegar have been used in the world during different time periods. Vinegar is produced by a fermentation process. Foods with a high content of carbohydrates are a good source of vinegar. Review of the results of different studies performed on vinegar components reveals that the daily use of these components has a healthy impact on the physiological and chemical structure of the human body. During the era of Hippocrates, people used vinegar as a medicine to treat wounds, which means that vinegar is one of the ancient foods used as folk medicine. The purpose of the current review paper is to provide a detailed summary of the outcome of previous studies emphasizing the role of vinegar in treatment of different diseases both in acute and chronic conditions, its in vivo mechanism and the active role of different bacteria.

scholarly journals Study of nitrate levels in fruits and vegetables to assess the potential health risks in Bangladesh

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Rayhan Uddin ◽  
Mostak Uddin Thakur ◽  
Mohammad Zia Uddin ◽  
G. M. Rabiul Islam
Keyword(s):  
Cluster Analysis ◽  
Health Risks ◽  
Fruits And Vegetables ◽  
Risk Index ◽  
Daily Intake ◽  
Point Estimate ◽  
Nitrate Content ◽  
Nitrate Accumulation ◽  
Health Risk Index ◽  
Potential Health

AbstractNitrate is a chemical compound naturally present in fruits and vegetables. This study aims at assessing the nitrate levels and health risks arising from high consumption of fruits and vegetables in Bangladesh. Sixteen species of fruits and vegetables were examined for nitrates using High-Performance Liquid Chromatography with Photo Diode Array (PDA) detector. Ward’s hierarchical cluster analysis was carried out to identify the cluster of tested fruits and vegetables for the nitrate contents. A point estimate of the daily intake was applied to find the health risks that arise due to elevated levels of nitrate in fruits and vegetables. The results show that root and tuber vegetables accumulate significantly higher levels of nitrate in comparison to fruits and fruit vegetables (P < 0.05). In cluster analysis, the nitrate accumulation of fruits and vegetables show four clear clusters contributing to 29.54%, 7.17%, 4.42%, and 58.57% of the total nitrate content in the entire sample. The risk assessment of the Estimated Daily Intake (EDI) and Health Risk Index (HRI) of almost all the tested samples was in the acceptable range, except for radish, thereby indicating the acceptance of risk due to nitrate intake in Bangladesh. As nitrate may have had risk factor for health, during cultivation and storing the product should be properly monitored.

Toxicological Risk Associated with Consumption of Rice Sold in Uganda

2021 ◽  
Vol 2 (6) ◽  
Author(s):  
Leatitiah Namubiru ◽  
Denis Male ◽  
Ivan Mukisa Muzira ◽  
Yusuf Byenkya Byaruhanga
Keyword(s):  
Value Chain ◽  
Daily Intake ◽  
Hazard Index ◽  
Dietary Exposure ◽  
Carcinogenic Risk ◽  
Regulatory Body ◽  
Lifetime Cancer Risk ◽  
Potential Health ◽  
Timely Feedback ◽  
Rice Samples

Previous studies have reported the presence of aflatoxins (AFB1, AFB2, AFG1 and AFG2), heavy metals (As, Cd and Pb) and organochlorine pesticide residues (OCPs) in rice sold in Uganda. However, the potential health effects associated with consumption of rice have not been evaluated. The aim of this study was to evaluate the health risk of consuming rice sold in Uganda. A total of 45 packed and 30 open traded rice samples were randomly collected from retail outlets in the main rice trading areas of Uganda. Rice was analysed for AFB1, AFB2, AFG1 and AFG2, As, Cd, Pb and OCPs using AOAC standard methods. Dietary exposure of the consumers to contaminants was assessed using the estimated daily intake (EDI). The Hazard index (HI) and the incremental lifetime cancer risk (ILCR) were determined to define the non-carcinogenic and carcinogenic risk from contaminants, respectively. The potency of liver cancer cases in Uganda was 1.02E-5 and 1.05E-5 adults/year/100,000, and 6.50E-4 and 6.72E-5 infants /year/100,000 for open traded and packed rice, respectively. The values obtained for the ILCR for Arsenic detected in rice were 1.14E-2 and 7.28E-2 for adults and infants, respectively. The ILCR of all detected OCPs in adults and infants were higher than 1.0E-4, in both open traded and packed rice. This study established a potential carcinogenic risk from consumption of rice sold in Uganda in both infants and adults at the current level of contamination and consumption rate. Establishment of a monitoring system along the entire rice value chain; enforced by a national regulatory body can provide timely feedback on the levels of contamination and the progress in reducing the contamination burden.

scholarly journals Potential Health Risk to Humans Related to Accumulation of Brodifacoum and Bromadiolone in the Wheat Grown on Rodenticide Contaminated Soil

2019 ◽  
Vol 63 (3) ◽  
pp. 18-26
Author(s):  
R. Hromada ◽  
I. Miňo ◽  
Ľ. Korytár ◽  
E. Holotová ◽  
M. Ondrašovič ◽  
...  
Keyword(s):  
Health Risk ◽  
Active Ingredient ◽  
Contaminated Soil ◽  
Model Experiment ◽  
Scientific Literature ◽  
Daily Intake ◽  
Acceptable Daily Intake ◽  
Potential Health ◽  
Potential Health Risk

Abstract The aim of this study was to determine in a model experiment the potential residues of bromadiolone and brodifacoum in the wheat grown on soil treated with these rodenticides and to compare them with the respective acceptable daily intake (ADI) in order to obtain information lacking in the scientific literature. The study focused on the level of residues of chronic rodenticides Broder G, with the active ingredient brodifacoum, and DERATION G, with the active ingredient bromadiolone, in wheat (Triticum spp.). The preparations were used in the form of granular bait. In the wheat grown on the soil treated with 100 g.m−2 of the preparation BRODER G, the brodifacoum residues ranged from 0.012 to 0.0218 mg.kg−1, while the treatment of soil with 500 g.m−2 resulted in residues ranging between 0.0344 and 0.0436 mg.kg−1. When using the preparation DE-RATION G, bromadiolone residues ranged between 0.012 and 0.018 mg.kg−1 after the treatment of soil with 100 g.m−2 and between 0.030 and 0.0428 mg.kg−1 after the treatment with 500 g.m−2. We observed that the acceptable daily intake was exceeded significantly in all of the cases and the residual levels depended on the rodenticide dose. In the case of brodifacoum, the ADI was exceeded more than 700-fold at a dose of 100 g.m−2 and more than 1400-fold at a dose of 500 g.m−2 of soil. With bromadio-lone, the ADI was exceeded 150-fold at a dose of 100 g.m−2 and more than 350-fold at a dose of 500 g.m−2. This indicates the risk to consumers from such crops.

Characterization of microneedles and microchannels for enhanced transdermal drug delivery

2021 ◽  
Author(s):  
Ashana Puri ◽  
Hiep X Nguyen ◽  
Akeemat O Tijani ◽  
Ajay K Banga
Keyword(s):  
Transdermal Delivery ◽  
Transdermal Drug Delivery ◽  
Review Paper ◽  
Low Molecular Weight ◽  
Kinetic Properties ◽  
Different Types ◽  
And Performance ◽  
Tools And Techniques

Microneedle (MN)-based technologies are currently one of the most innovative approaches that are being extensively investigated for transdermal delivery of low molecular weight drugs, biotherapeutic agents and vaccines. Extensive research reports, describing the fabrication and applications of different types of MNs, can be readily found in the literature. Effective characterization tools to evaluate the quality and performance of the MNs as well as for determination of the dimensional and kinetic properties of the microchannels created in the skin, are an essential and critical part of MN-based research. This review paper provides a comprehensive account of all such tools and techniques.

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