scholarly journals Current Status of Mumps Virus Infection: Epidemiology, Pathogenesis, and Vaccine

Author(s):  
Shih-Bin Su ◽  
Hsiao-Liang Chang ◽  
Kow-Tong Chen

Mumps is an important childhood infectious disease caused by mumps virus (MuV). We reviewed the epidemiology, pathogenesis, and vaccine development of mumps. Previous studies were identified using the key words “mumps” and “epidemiology”, “pathogenesis” or “vaccine” in MEDLINE, PubMed, Embase, Web of Science, and Google Scholar. We excluded the articles that were not published in the English language, manuscripts without abstracts, and opinion articles from the review. The number of cases caused by MuV decreased steeply after the introduction of the mumps vaccine worldwide. In recent years, a global resurgence of mumps cases in developed countries and cases of aseptic meningitis caused by some mumps vaccine strains have renewed the importance of MuV infection worldwide. The performance of mumps vaccination has become an important issue for controlling mumps infections. Vaccine development and routine vaccination are still effective measures to globally reduce the incidence of mumps infections. During outbreaks, a third of MMR vaccine is recommended for groups of persons determined by public authorities.

Parasitology ◽  
2014 ◽  
Vol 141 (6) ◽  
pp. 725-732 ◽  
Author(s):  
XIAOSONG LIU ◽  
SHELLEY WALTON ◽  
KATE MOUNSEY

SUMMARYScabies is an infectious disease that is endemic in poorly resourced communities, and also common in industrialized countries. Although the disease, which is caused by infestation of Sarcoptes scabiei, is generally mild, the need for a vaccine against S. scabiei is proposed. The immunological mechanisms that control S. scabiei infection are discussed and the current status of scabies vaccine development reviewed. Future directions for scabies vaccine development are also addressed.


2018 ◽  
Vol 96 (1) ◽  
pp. 37-59 ◽  
Author(s):  
Marton Demeter

In this research, we analyzed all 79 Web of Science (WoS) indexed journals in communication and media studies to disclose main publication patterns. We found that English-language countries dominate the field in a greater extent than in other disciplines, and developing countries are in a weaker position than English-language developed countries not just in natural sciences but also in soft sciences. We found significant correlations between the nominal GDP, the per capita publication, and per capita GDP of a given country and its publication scores.


2012 ◽  
Vol 73 (3) ◽  
pp. 233-262 ◽  
Author(s):  
Bernadette A. Lear

This study identified nearly 700 English-language refereed journals in education and psychology that were founded in 2000–2009. Part one discusses the publishers, format, open-access availability, and current status of these publications. Titles were then searched against coverage lists of EBSCO Academic Search Complete, Gale Academic OneFile, ProQuest Central, ERIC, PsycINFO, Web of Science, DOAJ, Google Scholar, WorldCAT, and the library catalogs of the “Big Ten” universities to determine whether databases and libraries include these new publications. Subscription database coverage was poor, ranging from 8.8 percent (ProQuest Central) to 42.0 percent (PsycINFO). Psychology materials were heavily favored over education items in several databases. Although some library catalogs provide better title-level coverage, they are unable to search individual articles. Google Scholar only indexed the publishers’ versions of the journals in 143 (58.0%) of 247 cases examined. Significant differences in database coverage and library holdings were found when comparing publications of major corporations (Elsevier, Routledge/Taylor & Francis, Sage, Springer, and Wiley) against periodicals produced by smaller companies, colleges/universities, and scholarly/professional organizations. This article also describes a “ubiquity index” devised by the author to identify approximately 70 “journals of the decade” based on database coverage and library holdings. The study provides much cause for concern about the comprehensiveness and currency of existing discovery tools. It also offers evidence that the relationship between libraries and publishing conglomerates deserves further examination.


2008 ◽  
Vol 13 (16) ◽  
Author(s):  
B Kaic ◽  
I Gjenero-Margan ◽  
B Aleraj ◽  
S Ljubin-Sternak ◽  
T Vilibić-Čavlek ◽  
...  

We report on three cases of symptomatic transmission of the L-Zagreb mumps vaccine virus from three vaccinated children to five adult contacts. The five contact cases were parents of the vaccinated children and presented with parotitis and in one case also with aseptic meningitis. The etiology of the contacts' illness was determined by viral culture, genomic sequencing, serology and epidemiological linking. Two of the vaccinated children developed vaccine associated parotitis as an adverse event three weeks following immunization. Symptoms in contact cases developed five to seven weeks after the vaccination of the children. The five contact cases, as well as the three children with adverse events recovered completely. The children had been vaccinated with MMR vaccine produced by the Institute of Immunology Zagreb, each of them with a different lot. One of the possible explanations for these adverse events is that the very low levels of wild mumps virus circulation in the last decade, combined with waning immunity in those who received one dose of vaccine or suffered from mumps in childhood, resulted in susceptible young adults and that this unique epidemiological situation allows us to detect horizontal transmission of mumps vaccine virus.


PEDIATRICS ◽  
1978 ◽  
Vol 62 (6) ◽  
pp. 965-969
Author(s):  
Gregory F. Hayden ◽  
Stephen R. Preblud ◽  
Walter A. Orenstein ◽  
J. Lyle Conrad

Reported mumps in the United States has declined to all-time low levels following the increasingly widespread use of mumps-virus vaccine. Mumps vaccine has proven safe and effective. Its incorporation into combined live-virus vaccines, especially measles-mumps-rubella, has made mumps vaccination a practical and economically feasible component of routine immunization activities. Because of the favorable experience to date with mumps vaccine and the associated drop in mumps morbidity and mortality, mumps control programs likely will receive increasing public health attention in the coming years.


2020 ◽  
Author(s):  
Xiaolong Cai ◽  
Huajun Bai ◽  
Xiaoyan Zhang

The vaccine helps to provoke the immune system and is an efficacious means for disease prevention and treatment. At this particular time of the COVID-19 outbreak, the vaccine for COVID-19 is urgently needed to save tens of thousands of people’s lives. Here we give some basic information on vaccine classification, generation, and application, and make a brief review on the current status of COVID-19 vaccine and tumor vaccine development both in the clinical trial stage and pre-clinical stage. vaccine


Author(s):  
Wenting Yang ◽  
Jiantong Zhang ◽  
Ruolin Ma

Objective: The outbreak of infectious diseases has a negative influence on public health and the economy. The prediction of infectious diseases can effectively control large-scale outbreaks and reduce transmission of epidemics in rapid response to serious public health events. Therefore, experts and scholars are increasingly concerned with the prediction of infectious diseases. However, a knowledge mapping analysis of literature regarding the prediction of infectious diseases using rigorous bibliometric tools, which are supposed to offer further knowledge structure and distribution, has been conducted infrequently. Therefore, we implement a bibliometric analysis about the prediction of infectious diseases to objectively analyze the current status and research hotspots, in order to provide a reference for related researchers. Methods: We viewed “infectious disease*” and “prediction” or “forecasting” as search theme in the core collection of Web of Science from inception to 1 May 2020. We used two effective bibliometric tools, i.e., CiteSpace (Drexel University, Philadelphia, PA, USA) and VOSviewer (Leiden University, Leiden, The Netherlands) to objectively analyze the data of the prediction of infectious disease domain based on related publications, which can be downloaded from the core collection of Web of Science. Then, the leading publications of the prediction of infectious diseases were identified to detect the historical progress based on collaboration analysis, co-citation analysis, and co-occurrence analysis. Results: 1880 documents that met the inclusion criteria were extracted from Web of Science in this study. The number of documents exhibited a growing trend, which can be expressed an increasing number of experts and scholars paying attention to the field year by year. These publications were published in 427 different journals with 11 different document types, and the most frequently studied types were articles 1618 (83%). In addition, as the most productive country, the United States has provided a lot of scientific research achievements in the field of infectious diseases. Conclusion: Our study provides a systematic and objective view of the field, which can be useful for readers to evaluate the characteristics of publications involving the prediction of infectious diseases and for policymakers to take timely scientific responses.


PEDIATRICS ◽  
1969 ◽  
Vol 43 (5) ◽  
pp. 907-909
Author(s):  
Margaret H. D. Smith

Thank you for your thoughtful letter about mumps virus vaccine. We have had several letters over the past year from individuals and groups who, like yourselves, have been perturbed about the recommendations for the use of mumps vaccine. Let me first point out that the recommendations for the use of mumps vaccine, which seem to you confused and which others have referred to as "wishywashy," are not those alone of the Committee on Control of Infectious Disease, but that they concur very closely with those of the Advisory Committee on Immunization Practice of the Surgeon General.


2021 ◽  
Vol 7 ◽  
pp. 205520762110093
Author(s):  
Hind Bitar ◽  
Sarah Alismail

Objective To summarize the current status of, and the current expert opinions, recommendation and evidence associated with the use and implementation of electronic health (eHealth), telemedicine, and/or telehealth to provide healthcare services for chronic disease patients during the COVID-19 pandemic. Materials and methods We searched four electronic databases (PubMed, Google Scholar, Science Direct, and Web of Science Core Collection) to identify relevant articles published between 2019 and 2020. Searches were restricted to English language articles only. Two independent reviewers screened the titles, abstracts, and keywords for relevance. The potential eligible articles, papers with no abstract, and those that fall into the uncertain category were read in full text independently. The reviewers met and discussed which articles to include in the final review and reached a consensus. Results We identified 51 articles of which 25 articles met the inclusion criteria. All included articles indicated the promising potential of eHealth, telehealth, and/or telemedicine solutions in delivering healthcare services to patients living with chronic diseases/conditions during the COVID-19 pandemic. We synthesized the main findings into ten usages and eight recommendations concerning the different activities for delivering healthcare services remotely for those living with chronic diseases/conditions in the era of COVID-19. Discussion and conclusions There is limited evidence available about the effectiveness of such solutions. Further research is required during this pandemic to improve the credibility of evidence on telemedicine, telehealth, and/or eHealth-related outcomes for those living with chronic diseases.


1995 ◽  
Vol 34 (4III) ◽  
pp. 1025-1039 ◽  
Author(s):  
Yasmeen Mohiuddln

The purpose of the present paper is to formulate a composite index of the status of women and to rank both developed and developing countries on the basis of that index. This index is presented as an alternative or complement to the current status of women index, published by the Population Crisis Committee (PCC) and used by the World Bank and the United Nations, which focuses on indicators measuring health, education, employment, marriage and childbearing, and social equality. The paper argues that these indicators have a poverty-bias and measure women's status in terms of structural change rather than in terms of their welfare vis-ii-vis men. The PCC index is also based on the implicit assumption that women's status in developing countries ought to be defined in a similar way as in developed countries, thus including primarily only those indicators which are more relevant for developed countries. To remedy these defects, the paper presents an alternative composite index, hereafter labelled the Alternative Composite (AC) index, based on many more indicators reflecting women's issues in both developed and developing countries. The results of the statistical analysis show that the ranking of countries based on the AC index is significantly different from the PCC index.


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