scholarly journals Loneliness Is Associated with Depressive Affect, But Not with Most Other Symptoms of Depression in Community-Dwelling Individuals: A Network Analysis

Author(s):  
Roland von Känel ◽  
Sonja Weilenmann ◽  
Tobias R. Spiller

There is a strong relationship between loneliness and depression, but depression is a heterogeneous disorder. We examined the profile of depressive symptoms most strongly related to loneliness. Study participants were 2007 community-dwelling individuals (median age 31 years, 70.4% women) who completed an online survey on loneliness (single-item question: “never”, “sometimes”, “often”), depressive symptoms (Patient Health Questionnaire-9) and demographics. The relationship between loneliness and depressive symptoms was evaluated with linear regression and network analyses. The prevalence of loneliness (sometimes or often) and of moderate depression was 47.1% and 24.0%, respectively. Loneliness explained 26% of the variance in the total depressive symptom score (p < 0.001), independent of covariates. This result was almost exclusively explained by the relationship with a single depression symptom (“feeling down, depressed, or hopeless”), irrespective of whether loneliness was treated as a nominal or continuous variable. The findings of our study suggest that the role of loneliness in depression should not only be investigated at the syndrome level, but also at the symptom level. Studies are warranted to test whether targeted treatment of depressive affect is particularly effective against loneliness.

2019 ◽  
Author(s):  
Julian Burger ◽  
Margaret S. Stroebe ◽  
Pasqualina Perrig-Chiello ◽  
Henk A.W. Schut ◽  
Stefanie Spahni ◽  
...  

Background: Prior network analyses demonstrated that the death of a loved one potentially precedes specific depression symptoms, primarily loneliness, which in turn links to other depressive symptoms. In this study, we extend prior research by comparing depression symptom network structures following two types of marital disruption: bereavement versus separation. Methods: We fitted two Gaussian Graphical Models to cross-sectional data from a Swiss survey of older persons (145 bereaved, 217 separated, and 362 married controls), and compared symptom levels across bereaved and separated individuals. Results: Separated compared to widowed individuals were more likely to perceive an unfriendly environment and oneself as a failure. Both types of marital disruption were linked primarily to loneliness, from where different relations emerged to other depressive symptoms. Amongst others, loneliness had a stronger connection to perceiving oneself as a failure in separated compared to widowed individuals. Conversely, loneliness had a stronger connection to getting going in widowed individuals. Limitations: Analyses are based on cross-sectional between-subjects data, and conclusions regarding dynamic processes on the within-subjects level remain putative. Further, some of the estimated parameters in the network exhibited overlapping confidence intervals and their order needs to be interpreted with care. Replications should thus aim for studies with multiple time points and larger samples. Conclusions: The findings of this study add to a growing body of literature indicating that depressive symptom patterns depend on contextual factors. If replicated on the within-subjects level, such findings have implications for setting up patient-tailored treatment approaches in dependence of contextual factors.


Author(s):  
Glenn J. Wagner ◽  
Mary Slaughter ◽  
Bonnie Ghosh-Dastidar

We examined the relationship between depression (symptom type, diagnostic severity, and change over time) and adherence to HIV antiretroviral therapy (ART) with data from 3 longitudinal studies (N = 1021) of patients starting ART in Uganda. The Patient Health Questionnaire was used to assess depressive symptoms (total score; somatic and cognitive subscales) and categorize severity level. At baseline, 9% had major depression and 30% had minor depression; 82% were adherent (reported no missed ART doses in the past 7 days) at month 6 and 85% at month 12. Controlling for demographic and medical covariates, multivariate random-effects logistic regression models revealed that change in depression was not related to adherence; however, baseline total depression symptoms and cognitive symptoms in particular as well as major and minor depression were significant predictors of adherence. These findings highlight the need for early identification and aggressive treatment of depression to optimize ART adherence.


2018 ◽  
Vol 25 (6) ◽  
pp. 721-742 ◽  
Author(s):  
Sarah J. Ehlke ◽  
Michelle L. Kelley

This cross-sectional study examined whether depressive symptoms strengthened the relationship between different forms of sexual coercion victimization and drinking to cope motivations, which was hypothesized to influence alcohol use. Participants were 214 female undergraduates who completed an online survey. Participants who experienced any lifetime sexual coercion and reported higher depressive symptoms were the most likely to report drinking to cope motivations, which in turn were associated with alcohol use. Depressive symptoms did not strengthen the relationship between specific forms of sexual coercion, drinking to cope, and alcohol use. Increasing emotion regulation strategies among sexual coercion victims may reduce drinking.


2020 ◽  
Vol 60 (8) ◽  
pp. 1466-1475 ◽  
Author(s):  
Yaru Jin ◽  
Huaxin Si ◽  
Xiaoxia Qiao ◽  
Xiaoyu Tian ◽  
Xinyi Liu ◽  
...  

Abstract Background and Objectives Frailty is associated with depression in older adults and reduces their social support. However, the mechanism underlying such relationship remains unclear. We aim to examine whether social support acts as a mediator or moderator in the relationship between frailty and depression. Research Design and Methods This cross-sectional study was conducted among 1,779 community-dwelling older adults aged 60 and older. Frailty, social support, and depressive symptoms were measured by the Physical Frailty Phenotype, Social Support Rating Scale, and five-item Geriatric Depression Scale, respectively. Data were also collected on age, gender, years of schooling, monthly income, cognitive function, number of chronic diseases, physical function, and pain. Results Linear regression models showed that subjective support and support utilization, but not objective support, mediated and moderated the relationship between frailty and depressive symptoms. The Johnson–Neyman technique determined a threshold of 30 for subjective support, but not for support utilization, beyond which the detrimental effect of frailty on depressive symptoms was offset. Discussion and Implications Social support underlies the association of frailty with depression, and its protective role varies by type. Interventions on depression should address improving perceptions and utilization of social support among frail older adults rather than simply providing them with objective support.


Nutrients ◽  
2019 ◽  
Vol 11 (7) ◽  
pp. 1475 ◽  
Author(s):  
Emily K. Tarleton ◽  
Amanda G. Kennedy ◽  
Gail L. Rose ◽  
Abigail Crocker ◽  
Benjamin Littenberg

Depression is common, places a large burden on the patient, their family and community, and is often difficult to treat. Magnesium supplementation is associated with improved depressive symptoms, but because the mechanism is unknown, it is unclear whether serum magnesium levels act as a biological predictor of the treatment outcome. Therefore, we sought to describe the relationship between serum magnesium and the Patient Health Questionnaire (PHQ, a measure of depression) scores. A cross-sectional analysis of medical records from 3604 adults (mean age 62 years; 42% men) seen in primary care clinics between 2015 and 2018, with at least one completed PHQ were included. The relationship between serum magnesium and depression using univariate analyses showed a significant effect when measured by the PHQ-2 (−0.19 points/mg/dL; 95% CI −0.31, −0.07; P = 0.001) and the PHQ-9 (−0.93 points/mg/dL; 95% CI −1.81, −0.06; P = 0.037). This relationship was strengthened after adjusting for covariates (age, gender, race, time between serum magnesium and PHQ tests, and presence of diabetes and chronic kidney disease) (PHQ-2: −0.25 points/mg/dL; 95% CI −3.33, −0.09; P < 0.001 and PHQ-9: −1.09 95% CI −1.96 −0.21; P = 0.015). For adults seen in primary care, lower serum magnesium levels are associated with depressive symptoms, supporting the use of supplemental magnesium as therapy. Serum magnesium may help identify the biological mechanism of depressive symptoms and identify patients likely to respond to magnesium supplementation.


2020 ◽  
Vol 63 (1) ◽  
Author(s):  
Mario Amore ◽  
Martino Belvederi Murri ◽  
Pietro Calcagno ◽  
Paola Rocca ◽  
Alessandro Rossi ◽  
...  

Abstract Background. Greater levels of insight may be linked with depressive symptoms among patients with schizophrenia, however, it would be useful to characterize this association at symptom-level, in order to inform research on interventions. Methods. Data on depressive symptoms (Calgary Depression Scale for Schizophrenia) and insight (G12 item from the Positive and Negative Syndrome Scale) were obtained from 921 community-dwelling, clinically-stable individuals with a DSM-IV diagnosis of schizophrenia, recruited in a nationwide multicenter study. Network analysis was used to explore the most relevant connections between insight and depressive symptoms, including potential confounders in the model (neurocognitive and social-cognitive functioning, positive, negative and disorganization symptoms, extrapyramidal symptoms, hostility, internalized stigma, and perceived discrimination). Bayesian network analysis was used to estimate a directed acyclic graph (DAG) while investigating the most likely direction of the putative causal association between insight and depression. Results. After adjusting for confounders, better levels of insight were associated with greater self-depreciation, pathological guilt, morning depression and suicidal ideation. No difference in global network structure was detected for socioeconomic status, service engagement or illness severity. The DAG confirmed the presence of an association between greater insight and self-depreciation, suggesting the more probable causal direction was from insight to depressive symptoms. Conclusions. In schizophrenia, better levels of insight may cause self-depreciation and, possibly, other depressive symptoms. Person-centered and narrative psychotherapeutic approaches may be particularly fit to improve patient insight without dampening self-esteem.


2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S311-S312
Author(s):  
Fang-Yi Huang ◽  
Min Li

Abstract Objectives: The relationship between marital status and depression symptoms is well documented. However, how the negative economic shock affect relationship differ by gender and cohort is still indecisive. The dataset “2011 wave of the Taiwan Longitudinal Study in Aging” and logistic regression models were used in the study. The results: Marital status is related to depression symptoms, but it differs by gendered cohort. With considering financial shock, there is no difference of depressive symptom between divorced and married female. The divorced and widowed have 4.81 and 2.47 times higher of getting depression symptom than the married for baby boom female. Being divorced is 3.67 times higher of getting depressive symptoms than being married for baby boom male. For WWII female, the widows are 1.78 times higher to have depressive symptoms than the married. being divorced, widowers, and single are 3.32, 2.21 and 2.90 times higher of getting depressive symptoms than being married for WWII male. Being divorced is 3.67 times higher of getting depressive symptoms than being married for baby boom male. In conclusions, people with unstable marital statuses are more depressed than the married. In particular, the effect of unstable marital statuses on depression could be account for by financial decline for women but not men. Given the policy emphasis on those with unstable marital status and economic decline, divorce female and single baby boom female may represent particular groups in whom interventions designed to financially support.


2021 ◽  
Author(s):  
Vivian Huang

The current study examined the association between chronic stress (measured in allostatic load or AL), ER, and depressive symptoms in a group of community-dwelling older adults. It was hypothesized that chronic stress levels would mediate the relationship between ER and depressive symptoms. A total of 70 older adults aged 60 and older participated in the study. There were no significant associations found in the main analyses between the AL index and depressive symptoms, as well as no significant relationship was found between ER strategies and AL index, after controlling for age, sex, education, and perceived SES. However, perceived stress significantly mediated the relationship between maladaptive ER strategies and depressive symptoms, and the relationship between adaptive ER strategies and depressive symptoms. Given the small sample size and the lack of variability of the AL index, the study would benefit from a larger sample size to clarify the present results.


2020 ◽  
Vol 15 (2) ◽  
pp. 262-275
Author(s):  
Ng Chong Guan ◽  

During this COVID-19 pandemic, massive unverified information has flooded the social media platforms, causing heightened levels of anxiety and depressive symptoms among public. This study aimed to investigate the relationship between the COVID-19 related knowledge, attitude, and practice (KAP) and its psychological impact, such as anxiety and depressive symptoms in Malaysia population. A crosssectional online survey was conducted from 8th to 22nd April 2020, involving 227 respondents. The set of questionnaire included sociodemographic characteristics, the KAP questionnaire – 11 items on knowledge (K1-K11), 3 items on attitude (A1- A3), 4 items on practice (P1-P4), together with Patient Health Questionnaire (PHQ-9) and Generalised Anxiety Disorder (GAD-7) Scale. To evaluate the data, descriptive analysis, Chi-square test and item response theory analysis were implemented. The percentage of respondents who answered the true statements items from Knowledge component (K1-K3) correctly was almost 100%. However, that of items testing on COVID-19 myths (K4-K11) ranged from 38.8% to 95.2%. The only item from Attitude component which had less than 95% being answered correctly was A1 (78.9%), regarding face masks usage. From the Practice component, over 80% of respondents identified that they used social media to obtain updates on COVID-19 all the time. This is alarming as most of the information circulating on social media have not been verified by relevant authorities, which might lead to, and continuously reinforce anxiety-inducing myths. This study showed that lower overall KAP scores, particularly for Knowledge component items, are related to higher anxiety levels and more depressive symptoms.


2021 ◽  
Vol 8 ◽  
Author(s):  
Rick Yiu Cho Kwan ◽  
Paul Hong Lee ◽  
Daphne Sze Ki Cheung ◽  
Simon Ching Lam

The COVID-19 pandemic has affected more than 100 countries. Despite the global shortage of face masks, the public has adopted universal mask wearing as a preventive measure in many Asian countries. The COVID-19 mortality rate is higher among older people, who may find that wearing a face mask protects their physical health but jeopardizes their mental health. This study aimed to explore the associations between depressive symptoms, health beliefs, and face mask wearing behaviors among older people. By means of an online survey conducted between March and April 2020, we assessed depressive symptoms, health beliefs regarding COVID-19, and face mask use and reuse among community-dwelling older people. General linear models were employed to explore the associations among these variables. Of the 355 valid participants, 25.6% experienced depressive symptoms. Health beliefs regarding the perceived severity of disease (p = 0.001) and perceived efficacy of practicing preventive measures (p = 0.005) were positively associated with face mask use. Those who reused face masks (p = 0.008) had a stronger belief in disease severity (p &lt; 0.001), had poorer cues to preventive measures (p = 0.002), and were more likely to experience depressive symptoms. Mask reuse was significantly associated with depression only among those who perceived the disease as serious (p = 0.025) and those who had poorer cues to preventive measures (p = 0.004). In conclusion, health beliefs regarding perceived severity and efficacy contributed to more frequent face mask use, which was unrelated to depressive symptoms. Older people who had a stronger belief in disease severity had less adequate cues to preventive measures and reused face masks experienced greater depressive symptoms. A moderation effect of health beliefs (i.e., disease severity and cues to preventive measures) on face mask reuse and depression was observed.


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