scholarly journals Asbestos Exposure and Malignant Mesothelioma in Construction Workers—Epidemiological Remarks by the Italian National Mesothelioma Registry (ReNaM)

2021 ◽  
Vol 19 (1) ◽  
pp. 235
Author(s):  
Alessandra Binazzi ◽  
Davide Di Marzio ◽  
Marina Verardo ◽  
Enrica Migliore ◽  
Lucia Benfatto ◽  
...  
Keyword(s):  
Occupational Exposure ◽  
Malignant Mesothelioma ◽  
Asbestos Exposure ◽  
Construction Workers ◽  
Construction Sector ◽  
Historical Trend ◽  
Increasing Trend

Notwithstanding the ban in 1992, asbestos exposure for workers in the construction sector in Italy remains a concern. The purpose of this study is to describe the characteristics of malignant mesothelioma (MM) cases recorded by the Italian registry (ReNaM) among construction workers. Incident mesothelioma cases with a definite asbestos exposure have been analyzed. Characteristics of cases and territorial clusters of crude rates of MM in construction workers have been described, as well as the relation between asbestos use before the ban and the historical trend of workforce in the construction sector in Italy. ReNaM has collected 31,572 incident MM cases in the period from 1993 to 2018 and asbestos exposure has been assessed for 24,864 (78.2%) cases. An occupational exposure has been reported for 17,191 MM cases (69.1% of subjects with a definite asbestos exposure). Among them, 3574 had worked in the construction sector, with an increasing trend from 15.8% in the 1993–98 period to 23.9% in 2014–2018 and a ubiquitous territorial distribution. The large use of asbestos in construction sector before the ban makes probability of exposure for workers a real concern still today, particularly for those working in maintenance and removal of old buildings. There is a clear need to assess, inform, and prevent asbestos exposure in this sector.

scholarly journals Survival of Korean Patients with Malignant Pleural Mesothelioma Compensated for the Asbestos Injury Relief

2021 ◽  
Vol 11 (20) ◽  
pp. 9713
Author(s):  
Min-Sung Kang ◽  
Sung-Soo Lee ◽  
Soon-Chan Kwon ◽  
Da-An Huh ◽  
Yong-Jin Lee
Keyword(s):  
Prognostic Factors ◽  
Occupational Exposure ◽  
Malignant Pleural Mesothelioma ◽  
Malignant Mesothelioma ◽  
Asbestos Exposure ◽  
Performance Status ◽  
Smoking History ◽  
Pleural Mesothelioma ◽  
Histological Subtype ◽  
Epidemiologic Characteristics

Background: The purpose of this study was to identify the epidemiologic characteristics and prognostic factors for malignant pleural mesothelioma in Korea, which are currently insufficient. The data were derived from malignant mesothelioma patients who registered under the Asbestos Injury Relief Act; Methods: A total of 728 patients received compensation from the Asbestos Injury Relief Act due to malignant mesothelioma between 2011 and 2015. Of these, 313 patients (43.0%) with malignant pleural mesothelioma were included in the study. The study variables were sex (male, female), age at diagnosis (<59, 60–69, ≥70), smoking history (yes, no), surgery (yes, no), chemotherapy (yes, no), occupational exposure to asbestos (yes, no), and histological subtype (epithelioid, nonepithelioid); Results: Median survival of mesothelioma was 8.0 months (95% confidence interval: 6.2 to 9.8). The 1-year, 2-year, and 5-year survival rates (%) were 43.5%, 23.6%, and 12.5%, respectively. In multivariate analysis of Cox’s proportional hazards model; sex, age, smoking history, occupational asbestos exposure, and histological subtype were not significant prognostic factors, but surgery and chemotherapy combined was a significant predictor; Conclusions: Although the representativeness of these data is limited, our study estimates the epidemiologic characteristics of malignant pleural mesothelioma. Non-occupational exposure had a similar prognosis to occupational asbestos exposure, and there was no sex difference. In addition, it was found that receiving a combination of surgery and chemotherapy affects the survival rate, but there is a limitation in that factors such as performance status, comorbidities, and stage that contribute to survival are not considered.

scholarly journals Malignant Mesothelioma of the Tunica Vaginalis Testis—A Malignancy Associated With Asbestos Exposure and Trauma: A Case Report and Literature Review

2019 ◽  
Vol 7 ◽  
pp. 232470961982733 ◽  
Author(s):  
AAM A. Baqui ◽  
Nicholas A. Boire ◽  
Tajruba T. Baqui ◽  
Dhanan J. Etwaru
Keyword(s):  
Case Report ◽  
Occupational Exposure ◽  
Literature Review ◽  
Malignant Mesothelioma ◽  
Unusual Case ◽  
Surgical Intervention ◽  
Asbestos Exposure ◽  
Tunica Vaginalis ◽  
Tunica Vaginalis Testis ◽  
History Of

In this article, we report an unusual case of a malignant mesothelioma of the testis, presenting as hydrocele. The patient has a known medical history of trauma and occupational exposure to asbestos. The clinical features of this injury are discussed together with its immunohistochemistry. Surgical intervention is discussed due to the nature of this pathology.

scholarly journals Mesothelioma in Agriculture in Lombardy, Italy: An Unrecognized Risk

2021 ◽  
Vol 18 (1) ◽  
pp. 358
Author(s):  
Carolina Mensi ◽  
Barbara Dallari ◽  
Marco Polonioli ◽  
Luciano Riboldi ◽  
Dario Consonni ◽  
...  
Keyword(s):  
Cohort Studies ◽  
Malignant Mesothelioma ◽  
Asbestos Exposure ◽  
Agricultural Workers ◽  
Wine Production ◽  
Maintenance And Repair ◽  
Lombardy Region ◽  
Frequent Exposure ◽  
Agricultural Setting ◽  
Jute Bags

Cohort studies showed consistently low risks for malignant mesothelioma (MM) among agricultural workers, however the investigated exposures did not include asbestos. Our aim is to describe sources of asbestos exposure of MM in agriculture. Twenty-six MM cases in agricultural or seed trades workers were identified through the MM registry of the Lombardy region, Italy in 2000–2016. Asbestos exposures were investigated through a standardized questionnaire. The most frequent exposure circumstances were recycled jute bags previously containing asbestos (11 cases) and maintenance and repair of asbestos roofs (12 subjects). Three subjects performed maintenance and repair of tractor asbestos brakes and two used asbestos filters for wine production. Our data suggest asbestos exposure opportunities in the agricultural setting, underlining the need to look for this exposure in subjects affected with mesothelioma.

scholarly journals Scalp Metastasis of Mesothelioma

2021 ◽  
Author(s):  
İlkin Yetişkin ◽  
Berna Eren Kömürcüoğlu ◽  
Eylem Yıldırım
Keyword(s):  
Adrenal Gland ◽  
Malignant Mesothelioma ◽  
Malignant Tumor ◽  
Late Stage ◽  
Poor Prognosis ◽  
Early Stage ◽  
Asbestos Exposure ◽  
Distant Metastases ◽  
Rare Neoplasm ◽  
Scalp Metastasis

Mesothelioma is a primary malignant tumor of the mesothelial cells lining the pleura, pericardium and peritoneum, which is frequently seen between the ages of 40-60. Malignant mesothelioma (MM) is a rare neoplasm with a poor prognosis, usually associated with asbestos exposure. It is characterized by aggressive local invasion and metastatic spread. Extrathoracic lymphogenous-hematogenous metastases are rare at the time of diagnosis and in the early stage. However, metastases develop in at least half of the cases in the late stage of the disease. After the spread of serous membranes, distant metastases to the bone, adrenal gland, and liver are frequently observed. Skin and scalp metastases are rarely observed. Our case MPM is presented because it is a rare scalp metastasis.

scholarly journals Factors involved in the perceived risk of construction workers

DYNA ◽  
2015 ◽  
Vol 82 (192) ◽  
pp. 257-265
Author(s):  
Ignacio Rodríguez-Garzón ◽  
Myriam Martínez-Fiestas ◽  
Antonio Delgado-Padial ◽  
Valeriano Lucas-Ruiz
Keyword(s):  
Statistical Analysis ◽  
Perceived Risk ◽  
Exploratory Study ◽  
Classification Tree ◽  
Construction Workers ◽  
Important Predictor ◽  
Construction Sector ◽  
Catastrophic Risk ◽  
Psychometric Paradigm ◽  
Personal Vulnerability

This article is an exploratory study of perceived risk in the construction sector. We used a sample of 514 workers in Spain, Peru and Nicaragua. The method used was the psychometric paradigm and, under its assumptions we have studied nine factors or qualitative attributes of risk. The main statistical analysis was carried out using a classification tree. As a result is obtained that four of the nine attributes studied predict significantly the perceived risk of the sample. The attribute on the delay of the consequences has been the most important predictor in the model, followed by the attribute that explores the potential catastrophic risk and the attribute that explores the serious consequences. Finally the attribute related to the personal vulnerability has emerged. The implications of the results are exposed.

scholarly journals Association of Mesothelioma Deaths With Cumulated Neighborhood Exposures Due to a Large-Scale Asbestos Cement Plant in Amagasaki City, Japan: A Nested Case-control Study

2021 ◽  
Author(s):  
Yuri Kitamura ◽  
Ling Zha ◽  
Rong Liu ◽  
Masayuki Shima ◽  
Tomoki Nakaya ◽  
...  
Keyword(s):  
Occupational Exposure ◽  
Large Scale ◽  
Case Control Study ◽  
Conditional Logistic Regression ◽  
Asbestos Exposure ◽  
Case Control ◽  
Asbestos Cement ◽  
Nested Case Control ◽  
Dose Dependent ◽  
Control Study

Abstract BackgroundAlthough a causal relationship between mesothelioma and asbestos exposure is well known, few studies have shown a relationship to non-occupational exposure, including neighborhood exposure, most likely because of the large effect size of occupational exposure. The aim of this study was to quantify the risk of malignant mesothelioma death associated with neighborhood asbestos exposure due to a large-scale asbestos-cement (AC) plant in Amagasaki, Japan, by properly adjusting for occupational exposure. MethodsThis was a nested case-control study in which a fixed population of 143,929 residents who had been living in Amagasaki City between 1975 and 2002 were followed from 2002 to 2015. All 133 cases and 403 matched controls were interviewed about their occupational, domestic, household, and neighborhood asbestos exposures. Odds ratios (ORs) for mesothelioma death associated with neighborhood exposure were estimated by a conditional logistic-regression model that adjusted for other asbestos exposures. We adopted cumulative indices that considered residence-specific asbestos (crocidolite) concentrations and durations during the potential exposure period of 1957-1975 to evaluate individual neighborhood exposures.ResultsThere was an increasing, dose-dependent risk of mesothelioma death associated with neighborhood exposure, demonstrated by ORs in the highest quintile category that were 21.4 (95%CI: 5.8 to 79.2) for all, 23.7 (95% CI: 3.8-147.2) for males and 26.0 (95% CI: 2.8-237.5) for females, compared to the lowest quintile, respectively. These results clearly demonstrated no substantial differences between males and females in relation to the magnitude of risk from neighborhood exposure.Our findings suggest that the risk of mesothelioma death associated with neighborhood exposure persists and will not be diminished for many years, even though it has been decades since the AC plant closed. ConclusionsBy adjusting for occupational and other asbestos exposures, a dose-dependent relationship was demonstrated between mesothelioma death and neighborhood asbestos exposure from a large-scale AC plant.

scholarly journals A CLINICAL STUDY OF MALIGNANT MESOTHELIOMA

2021 ◽  
Vol 5 (5) ◽  
Author(s):  
Ankit Agarwal ◽  
Abhishek Padhiar ◽  
Arun Pandey ◽  
Giriraj Prajapati
Keyword(s):  
Weight Loss ◽  
Chest Pain ◽  
Malignant Mesothelioma ◽  
Asbestos Exposure ◽  
Symptom Duration ◽  
Karnofsky Performance Score ◽  
Survival Times ◽  
Aggressive Tumor ◽  
Histopathological Type ◽  
Diagnosis Date

Background: Malignant Mesothelioma (MM) is a rare but rapidly fatal and aggressive tumor of the pleura and peritoneum with limited knowledge of its natural history. Methods: 100 patients with histopathological MM diagnosis were included. The data obtained from patient files were recorded on standard forms, prepared in advance. Age, gender, hometown, residence, asbestos usage history, latent period between asbestos exposure and diagnosis, symptoms, symptom duration, diagnosis date, diagnostic method, localization, histopathological type, routine laboratory results, stage, karnofsky performance score (KPS), treatment regimen, pleurodesis, treatment response, date of death and survival times of patients were all recorded on the forms. Results: The mean age of patients 52.31±12.36 Yrs. 62 patients were male and 38 female. Environmental asbestos exposure was determined in 75.00% of patients At diagnosis, 76.00% patients had dyspnea; 71.00% weight loss; and 64.00% chest pain. A total of 48.00% patients were smokers. Mean survival time was found to be 9.3 months in our study. Conclusion: MM related to asbestos exposure is seen frequently in Southern Rajastan. Patients present with the typical clinical features of dyspnea, weight loss, and chest pain. Keywords: MM, Absestos, Dyspnea.

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