scholarly journals Hepatotoxicity: Molecular Mechanisms and Pathophysiology

2019 ◽  
Vol 20 (1) ◽  
pp. 211
Author(s):  
Rolf Teschke
Keyword(s):  
Broad Spectrum ◽  
Molecular Mechanisms ◽  
Special Issue ◽  
Current Special Issue

The current Special Issue is devoted to the broad spectrum of hepatotoxicity with its molecular mechanisms and pathophysiology, presented in eight publications [...]

scholarly journals Oral and Maxillo-Facial Manifestations of Systemic Diseases: An Overview

Medicina ◽  
2021 ◽  
Vol 57 (3) ◽  
pp. 271
Author(s):  
Saverio Capodiferro ◽  
Luisa Limongelli ◽  
Gianfranco Favia
Keyword(s):  
Early Diagnosis ◽  
Oral Cavity ◽  
Head And Neck ◽  
Clinical Outcomes ◽  
Systemic Disease ◽  
Clinical Manifestations ◽  
Systemic Diseases ◽  
Special Issue ◽  
Hard Tissues ◽  
Current Special Issue

Many systemic (infective, genetic, autoimmune, neoplastic) diseases may involve the oral cavity and, more generally, the soft and hard tissues of the head and neck as primary or secondary localization. Primary onset in the oral cavity of both pediatric and adult diseases usually represents a true challenge for clinicians; their precocious detection is often difficult and requires a wide knowledge but surely results in the early diagnosis and therapy onset with an overall better prognosis and clinical outcomes. In the current paper, as for the topic of the current Special Issue, the authors present an overview on the most frequent clinical manifestations at the oral and maxillo-facial district of systemic disease.

scholarly journals Advances in the Molecular Mechanisms of Abscisic Acid and Gibberellins Functions in Plants

2021 ◽  
Vol 22 (11) ◽  
pp. 6080
Author(s):  
Víctor Quesada
Keyword(s):  
Abscisic Acid ◽  
Molecular Mechanisms ◽  
Original Research ◽  
Special Issue ◽  
Research Papers

In this special issue entitled, “Advances in the Molecular Mechanisms of Abscisic Acid and Gibberellins Functions in Plants”, eight articles are collected, with five reviews and three original research papers, which broadly cover different topics on the abscisic acid (ABA) field and, to a lesser extent, on gibberellins (GAs) research [...]

scholarly journals Special Issue: “Advances in Structural Mechanics Modeled with FEM”

Materials ◽  
2021 ◽  
Vol 14 (4) ◽  
pp. 780
Author(s):  
Angelo Marcello Tarantino ◽  
Carmelo Majorana ◽  
Raimondo Luciano ◽  
Michele Bacciocchi
Keyword(s):  
Finite Element Method ◽  
Finite Element ◽  
Structural Mechanics ◽  
The Finite Element Method ◽  
Special Issue ◽  
Numerical Investigations ◽  
Current Special Issue ◽  
Element Method

The current Special Issue entitled “Advances in Structural Mechanics Modeled with FEM” aims to collect several numerical investigations and analyses focused on the use of the Finite Element Method (FEM) [...]

scholarly journals Civil Engineering and Symmetry

Symmetry ◽  
2019 ◽  
Vol 11 (4) ◽  
pp. 501 ◽  
Author(s):  
Edmundas Kazimieras Zavadskas ◽  
Romualdas Bausys ◽  
and Jurgita Antucheviciene
Keyword(s):  
Decision Making ◽  
Review Process ◽  
Civil Engineering ◽  
Peer Review Process ◽  
Research Management ◽  
Decision Makers ◽  
Environmental Benefits ◽  
Special Issue ◽  
Optimisation Methods ◽  
Current Special Issue

A topic of utmost importance in civil engineering is finding optimal solutions throughout the life cycle of buildings and infrastructural objects, including their design, manufacturing, use, and maintenance. Operational research, management science, and optimisation methods provide a consistent and applicable groundwork for engineering decision-making. These topics have received the interest of researchers, and, after a rigorous peer-review process, eight papers have been published in the current special issue. The articles in this issue demonstrate how solutions in civil engineering, which bring economic, social and environmental benefits, are obtained through a variety of methodologies and tools. Usually, decision-makers need to take into account not just a single criterion, but several different criteria and, therefore, multi-criteria decision-making (MCDM) approaches have been suggested for application in five of the published papers; the rest of the papers apply other research methods. The methods and application case studies are shortly described further in the editorial.

Career Education: Concluding Remarks

2019 ◽  
Vol 46 (6) ◽  
pp. 665-669
Author(s):  
Rachel Gali Cinamon ◽  
Hanoch Flum ◽  
Erin E. Hardin
Keyword(s):  
Career Education ◽  
Special Issue ◽  
Future Studies ◽  
Rapid Changes ◽  
The World ◽  
Current Special Issue ◽  
Education Work

The interventions presented in the current special issue have the potential to decrease social and economic gaps. At the same time, several important aspects that are central to the rapid changes in education and in the world of work were not included or given minimal attention in these interventions. In this concluding article, we reflect upon these issues in the hope that future studies and career education work will focus and elaborate upon theme.

scholarly journals The role of drugs in the control of parasitic nematode infections: must we do without?

Parasitology ◽  
1997 ◽  
Vol 114 (7) ◽  
pp. 137-144 ◽  
Author(s):  
M. H. ROOS
Keyword(s):  
Broad Spectrum ◽  
Molecular Mechanisms ◽  
Parasite Species ◽  
Parasitic Nematode ◽  
New Drugs ◽  
Pharmaceutical Companies ◽  
Parasitic Helminths ◽  
Parasite Populations ◽  
Drug Resistant Parasite

Parasitic helminths (worms) cause serious infectious diseases in humans and domestic animals. Control of these infections relies mostly on chemotherapeutics (the anthelmintics), but resistance has developed against most of these broad-spectrum drugs in many parasite species. These resistant parasites are being used to elucidate the molecular mechanisms of drug resistance and drug action. This has led to the development of sensitive assays to detect resistant parasites, but this has not delayed the emergence of additional drug resistant parasite populations. Therefore, as development of new drugs by pharmaceutical companies is slow, we may have to be prepared for a time when broad-spectrum drugs are no longer effective, especially against worms of sheep.

scholarly journals Osteoporosis: From Molecular Mechanisms to Therapies 2.0

2020 ◽  
Vol 21 (21) ◽  
pp. 8005
Author(s):  
Chih-Hsin Tang
Keyword(s):  
Side Effects ◽  
Bone Resorption ◽  
Bone Formation ◽  
Molecular Mechanisms ◽  
Current Understanding ◽  
Special Issue ◽  
Trabecular Microarchitecture ◽  
Anabolic Agent ◽  
Skeletal Disorder

Osteoporosis is a common skeletal disorder, occurring as a result of an imbalance between bone resorption and bone formation, with bone breakdown exceeding bone building. Bone resorption inhibitors, e.g., bisphosphonates, have been designed to treat osteoporosis. Teriparatide, an anabolic agent, stimulates bone formation and corrects the characteristic changes in the trabecular microarchitecture. However, these drugs are associated with significant side effects. It is therefore crucial that we continue to research the pathogenesis of osteoporosis and seek novel modes of therapy. This editorial summarizes and discusses the themes of the ten articles published in our Special Issue “Osteoporosis: From Molecular Mechanisms to Therapies 2.0”, a continuation of our 2019 Special Issue "Osteoporosis: From Molecular Mechanisms to Therapies" (https://www.mdpi.com/journal/ijms/special_issues/osteoporosis_ijms). These Special Issues detail important global scientific findings that contribute to our current understanding of osteoporosis.

What is a verb?

2019 ◽  
Vol 14 (2) ◽  
pp. 169-188
Author(s):  
Eva Smolka ◽  
Dorit Ravid
Keyword(s):  
Building Blocks ◽  
The Other ◽  
Special Issue ◽  
Thematic Roles ◽  
Semitic Languages ◽  
General Terms ◽  
Lexical Items ◽  
The One ◽  
Current Special Issue ◽  
Structure And Functions

Abstract Verbs constitute one of the basic building blocks of a clause, setting the structure of arguments and expressing the relationships among nouns in various thematic roles. In general terms, verbs are lexical items expressing verb-oriented notions such as activities, processes, and states. In morphology-rich languages, the syntactic and lexical roles of verbs are mediated by typologically-oriented morphological means. The current Special Issue contrasts the structure and functions of verbs in languages from two morphologically rich, yet typologically different families. The articles in the Special Issue present spoken and written aspects of verbs in usage and development in German (a Germanic language) on the one hand, in Hebrew, Neo-Aramaic, and Arabic (Semitic languages), on the other. From a theoretical linguistic perspective, we ask how the different typological features of these languages affect the function of verbs in sentences, and from a psycholinguistic perspective, we ask how typological differences affect the processing of verbs in the mature minds of adults and in the developing minds of children.

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