scholarly journals The Bioactive Core and Corona Synergism of Quantized Gold Enables Slowed Inflammation and Increased Tissue Regeneration in Wound Hypoxia

2020 ◽  
Vol 21 (5) ◽  
pp. 1699
Author(s):  
Lu-Chen Yeh ◽  
Shu-Ping Chen ◽  
Fang-Hsuean Liao ◽  
Te-Haw Wu ◽  
Yu-Ting Huang ◽  
...  
Keyword(s):  
Wound Healing ◽  
Tissue Regeneration ◽  
Electrostatic Interactions ◽  
Active Sites ◽  
Dual Function ◽  
Critical Aspect ◽  
Liquid Form ◽  
Catalytic Active Sites ◽  
Vital Factor

The progress of wound regeneration relies on inflammation management, while neovascular angiogenesis is a critical aspect of wound healing. In this study, the bioactive core and corona synergism of quantized gold (QG) were developed to simultaneously address these complicated issues, combining the abilities to eliminate endotoxins and provide oxygen. The QG was constructed from ultrasmall nanogold and a loosely packed amine-based corona via a simple process, but it could nonetheless eliminate endotoxins (a vital factor in inflammation also called lipopolysaccharides) and provide oxygen in situ for the remodeling of wound sites. Even while capturing endotoxins through electrostatic interactions, the catalytic active sites inside the nanogold could maintain its surface accessibility to automatically transform the overexpressed hydrogen peroxide in hypoxic wound regions into oxygen. Since the inflammatory stage is an essential stage of wound healing, the provision of endotoxin clearance by the outer organic corona of the QG could slow inflammation in a way that subsequently promoted two other important stages of wound bed healing, namely proliferation and remodeling. Relatedly, the efficacy of two forms of the QG, a liquid form and a dressing form, was demonstrated at wound sites in this study, with both forms promoting the development of granulation, including angiogenesis and collagen deposition. Thus, the simply fabricated dual function nanocomposite presented herein not only offers reduced batch-to-batch variation but also increased options for homecare treatments.

scholarly journals In Situ Construction of Ag/TiO2/g-C3N4 Heterojunction Nanocomposite Based on Hierarchical Co-Assembly with Sustainable Hydrogen Evolution

Nanomaterials ◽  
2019 ◽  
Vol 10 (1) ◽  
pp. 1 ◽  
Author(s):  
Rui Geng ◽  
Juanjuan Yin ◽  
Jingxin Zhou ◽  
Tifeng Jiao ◽  
Yao Feng ◽  
...  
Keyword(s):  
Hydrogen Evolution ◽  
Self Assembly ◽  
Active Sites ◽  
Carrier Transport ◽  
Synergistic Effects ◽  
Electron Hole ◽  
Simple Strategy ◽  
Promising Strategy ◽  
Catalytic Active Sites

The construction of heterojunctions provides a promising strategy to improve photocatalytic hydrogen evolution. However, how to fabricate a nanoscale TiO2/g-C3N4 heterostructure and hinder the aggregation of bulk g-C3N4 using simple methods remains a challenge. In this work, we use a simple in situ construction method to design a heterojunction model based on molecular self-assembly, which uses a small molecule matrix for self-integration, including coordination donors (AgNO3), inorganic titanium source (Ti(SO4)2) and g-C3N4 precursor (melamine). The self-assembled porous g-C3N4 nanotube can hamper carrier aggregation and it provides numerous catalytic active sites, mainly via the coordination of Ag+ ions. Meanwhile, the TiO2 NPs are easily mineralized on the nanotube template in dispersive distribution to form a heterostructure via an N–Ti bond of protonation, which contributes to shortening the interfacial carrier transport, resulting in enhanced electron-hole pairs separation. Originating from all of the above synergistic effects, the obtained Ag/TiO2/g-C3N4 heterogenous photocatalysts exhibit an enhanced H2 evolution rate with excellent sustainability 20.6-fold-over pure g-C3N4. Our report provides a feasible and simple strategy to fabricate a nanoscale heterojunction incorporating g-C3N4, and has great potential in environmental protection and water splitting.

An iron foam acts as a substrate and iron source for the in situ construction of a robust transition metal phytate electrocatalyst for overall water splitting

2020 ◽  
Vol 4 (1) ◽  
pp. 331-336 ◽  
Author(s):  
Xiaojuan Chen ◽  
Yan Meng ◽  
Taotao Gao ◽  
Jinmei Zhang ◽  
Xiaoqin Li ◽  
...  
Keyword(s):  
Transition Metal ◽  
Water Splitting ◽  
Active Sites ◽  
Iron Source ◽  
Overall Water Splitting ◽  
Catalytic Active Sites ◽  
3D Networks

The cheap iron foam as a 3D substrate for in situ electrochemical preparing bi-functional electrocatalyst. The introduction of phytates facilitates the construction of 3D networks and the join of Co and Fe further creates more catalytic active sites.

In situ Time-Resolved Small-Angle X-ray Scattering Reveals the Formation Kinetics of Polyelectrolyte Complex Micelles

2019 ◽  
Author(s):  
Hao Wu ◽  
Jeffrey Ting ◽  
Siqi Meng ◽  
Matthew Tirrell
Keyword(s):  
Small Angle ◽  
Self Assembly ◽  
Electrostatic Interactions ◽  
Polyelectrolyte Complex ◽  
Time Resolved ◽  
X Ray ◽  
X Ray Scattering ◽  
Kinetics Of ◽  
Ray Scattering

We have directly observed the <i>in situ</i> self-assembly kinetics of polyelectrolyte complex (PEC) micelles by synchrotron time-resolved small-angle X-ray scattering, equipped with a stopped-flow device that provides millisecond temporal resolution. This work has elucidated one general kinetic pathway for the process of PEC micelle formation, which provides useful physical insights for increasing our fundamental understanding of complexation and self-assembly dynamics driven by electrostatic interactions that occur on ultrafast timescales.

scholarly journals Electrokinetic and in situ spectroscopic investigations of CO electrochemical reduction on copper

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Jing Li ◽  
Xiaoxia Chang ◽  
Haochen Zhang ◽  
Arnav S. Malkani ◽  
Mu-jeng Cheng ◽  
...  
Keyword(s):  
Mass Transport ◽  
Active Sites ◽  
Gas Diffusion ◽  
Reduction Reaction ◽  
Adsorbed Hydrogen ◽  
Diffusion Type ◽  
Proton Coupled Electron Transfer ◽  
Alkaline Electrolytes ◽  
Reaction Orders

AbstractRigorous electrokinetic results are key to understanding the reaction mechanisms in the electrochemical CO reduction reaction (CORR), however, most reported results are compromised by the CO mass transport limitation. In this work, we determined mass transport-free CORR kinetics by employing a gas-diffusion type electrode and identified dependence of catalyst surface speciation on the electrolyte pH using in-situ surface enhanced vibrational spectroscopies. Based on the measured Tafel slopes and reaction orders, we demonstrate that the formation rates of C2+ products are most likely limited by the dimerization of CO adsorbate. CH4 production is limited by the CO hydrogenation step via a proton coupled electron transfer and a chemical hydrogenation step of CO by adsorbed hydrogen atom in weakly (7 < pH < 11) and strongly (pH > 11) alkaline electrolytes, respectively. Further, CH4 and C2+ products are likely formed on distinct types of active sites.

Sign in / Sign up

Export Citation Format

Share Document