scholarly journals The Role of DNA Degradation in the Estimation of Post-Mortem Interval: A Systematic Review of the Current Literature

2020 ◽  
Vol 21 (10) ◽  
pp. 3540 ◽  
Author(s):  
Pamela Tozzo ◽  
Salvatore Scrivano ◽  
Matteo Sanavio ◽  
Luciana Caenazzo
Keyword(s):  
Analytical Techniques ◽  
Dna Degradation ◽  
Post Mortem ◽  
Post Mortem Interval ◽  
Target Organs ◽  
The One ◽  
Definition Of ◽  
Meta Analyses

The determination of the post-mortal interval (PMI) is an extremely discussed topic in the literature and of deep forensic interest, for which various types of methods have been proposed. The aim of the manuscript is to provide a review of the studies on the post-mortem DNA degradation used for estimating PMI. This review has been performed following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses and the PRISMA Guidelines. Several analytical techniques have been proposed to analyse the post-mortem DNA degradation in order to use it to estimate the PMI. Studies focused mainly on animal models and on particular tissues. The results have been mixed: while on the one hand literature data in this field have confirmed that in the post-mortem several degradation processes involve nucleic acids, on the other hand some fundamental aspects are still little explored: the influence of ante and post-mortem factors on DNA degradation, the feasibility and applicability of a multiparametric mathematical model that takes into account DNA degradation and the definition of one or more target organs in order to standardize the results on human cases under standard conditions.

THE GENESIS OF LEGAL SUPPORT OF ACADEMIC VIRTUE

2020 ◽  
pp. 36-39
Author(s):  
I. Shopina
Keyword(s):  
Higher Education ◽  
Educational Activity ◽  
Ethical Values ◽  
The Third ◽  
Academic Responsibility ◽  
Third Stage ◽  
The One ◽  
Definition Of

The article is dedicated to the determination of the peculiarity of stages of legal support of academic virtue in Ukraine.It has been proven that the first stage for development of legal support to academic virtue has started in 2004, when the all-European processes of increasing the role of universities within a society have been initiated as well as the transformation ofrequirements to the participants of educational activity. This stage has been characterized by the acceptance of a Bucharestdeclaration on ethical values and principles of higher education in the European region (2-5 September 2004) and its result has been the establishment of an overall European discourse of academic virtue which included pedagogical, ethical and legalaspects of the phenomenon under research.It has been pointed out, that the third stage of legal support to academic virtue is related with stipulating in 2011 within aNational framework, the qualifications of adherence to proper academic virtue as the one that is considered to be necessary toinitiate, plan, implement and correct the subsequent process of a thorough scientific research of the level of basic skills andabilities. From this moment on there’s an active development of the terminological core dedicated to the issue of academicvirtue, there’s a preparation of suggestions to be implemented to the legislation on education, particularly, by determining thelegal definition of academic virtue, the forms and types of academic responsibility, and also the active reaffirming of ethicalrequirements on the academic virtues of teachers, scientists and individuals obtaining education in the codes of academicvirtues, approved in the course of gatherings of working teams or the scientific councils of universities.

Institutions, Models of Capitalism and Inequality in Income Distribution: An Empirical Investigation

2017 ◽  
Vol 17 (3) ◽  
pp. 651-685 ◽  
Author(s):  
Gilberto Antonelli ◽  
Pinuccia P Calia ◽  
Giovanni Guidetti
Keyword(s):  
Income Inequality ◽  
Income Distribution ◽  
Empirical Investigation ◽  
Econometric Evidence ◽  
Definition Of ◽  
The Empirical Analysis ◽  
Statistical Indicators ◽  
Different Levels

Abstract The article analyses the role of institutions in the determination of income inequality in a sample of OECD countries. Basing on the seminal approach by Amable, the article discusses the theoretical definition of model of capitalism. The basic idea is that each model of capitalism is defined by the cobweb of complementary relationships established among different institutions. Using a set of statistical indicators of the operation of institutions in two different years, 1995 and 2010, the empirical analysis points out five models of capitalism and exhibits how their composition has changed in this lapse of 15 years. In the following sections of the article, we investigate the role played by the model of capitalism in the determination of income distribution, measured through a standard Gini index. After controlling for a set of variables, the econometric evidence shows that different models of capitalism present significantly different levels of income inequality.

Brain Death

2017 ◽  
Author(s):  
Anupamaa Seshadri ◽  
Ali Salim
Keyword(s):  
Brain Death ◽  
Apnea Test ◽  
Brainstem Reflex ◽  
Practice Parameters ◽  
Confirmatory Tests ◽  
History Of ◽  
Pediatric Populations ◽  
Definition Of

The concept of “brain death” is one that has been controversial over time, requiring the development of clear guidelines to diagnose and give prognoses for patients after devastating neurologic injury. This review discusses the history of the definition of brain death, as well as the most recent guidelines and practice parameters on the determination of brain death in both the adult and pediatric populations. We provide specific and detailed instructions on the various clinical tests required, including the brain death neurologic examination and the apnea test, and discuss pitfalls in the diagnosis of brain death. This review also considers the most recent literature and guidelines as to the role of confirmatory tests making this diagnosis.  Key Words: apnea test, brain death, brainstem reflex, death examination

Ways of Applying Destination Management Concepts to the Development of Internal Tourism in Uzbekistan

2015 ◽  
pp. 172-190
Author(s):  
Bakhtiyor Navruz-Zoda ◽  
Nutfillo Ibragimov
Keyword(s):  
Supply And Demand ◽  
Tourism Industry ◽  
Location Selection ◽  
Tourism Management ◽  
Regional Management ◽  
Management Concepts ◽  
The One ◽  
Organic Combination

This chapter examines the role of the destination approach in the development of internal tourism in Uzbekistan. The trump-card of tourism in Uzbekistan is ancient cities like Tashkent, Samarkand, Shakhrisabz, Bukhara and Khiva. The chapter is focused on substantiation of destination model of tourism management, based on a junction of regional management and marketing theories. In order to reform the one-dimensional “package” system of tourism supply that operates in Uzbekistan to a multi-sided “integration” system it is recommended to run “creating destinations” policy in the tourism industry. That implies the creation process of integrated tourist destination based on organic combination of tourism supply and demand. The chapter describes seven stages of destination creating process: determination of purpose of visit in tourist location; selection of sights from destinations; clarification and analyzing destinations creating factors, explanation principles of creating destination; development criteria of creating destinations; creation of attractive destinations; arrangement of destination management system.

The Crime of Aggression and the United Nations Security Council

2007 ◽  
Vol 20 (4) ◽  
pp. 867-894 ◽  
Author(s):  
NIELS BLOKKER
Keyword(s):  
Security Council ◽  
Criminal Court ◽  
United Nations Security Council ◽  
International Court Of Justice ◽  
International Court ◽  
The One ◽  
International Law Commission ◽  
Difficult Issue

This contribution is dedicated to Professor John Dugard. It discusses the most difficult issue to be resolved in the negotiations on the crime of aggression: the role of the Security Council in the exercise of jurisdiction over this crime by the International Criminal Court. The International Law Commission suggested a solution in the 1990s, but failing the required support and in the absence of subsequent agreement the 1998 Rome Conference could only prospectively give the Court jurisdiction over the crime of aggression. The post-Rome negotiations are characterized by, on the one hand, support from the five permanent members of the Security Council for the thesis that it should be exclusively for the Security Council to determine whether or not an act of aggression has been committed (as a precondition for the exercise of jurisdiction by the ICC) and, on the other hand, a rejection of this thesis combined with a search for alternatives by many other states. According to the analysis below, in relation to cases involving the crime of aggression the preferred way for the ICC to proceed is to exercise jurisdiction over this crime after a determination of state aggression has been made by the Security Council. Nevertheless, the view according to which such a determination could exclusively be made by the Council is rejected, on the basis of the rules of the Charter, the practice of the Security Council and the General Assembly, and decisions of the International Court of Justice. Finally, an alternative arrangement is suggested for the cases in which the Security Council is prevented from acting because of the use of the veto or because of lack of support from its members.

BLOOD GROUP AND HUMAN DISEASES (REVIEW OF LITERATURE)

2020 ◽  
Vol 65 (4) ◽  
pp. 216-221
Author(s):  
Frida Nasyrovna Gilmiyarova ◽  
N. A. Kolotyeva ◽  
V. I. Kuzmicheva ◽  
O. A. Gusyakova ◽  
I. A. Borodina ◽  
...  
Keyword(s):  
Blood Group ◽  
Gastrointestinal Diseases ◽  
Antigenic Determinants ◽  
Blood Group Antigens ◽  
Oral Diseases ◽  
Group Type ◽  
Pathological Conditions ◽  
Definition Of ◽  
Meta Analyses

AB0 blood group antigens were discovered over a century ago; however, it is still important to study their role in development of various pathological conditions. Today it is known that antigenic determinants of this blood group are present not only on erythrocyte membrane but also on other cells and tissues: platelets, gastrointestinal epithelium and salivary glands, respiratory system cells. In the last decade, a large number of studies have appeared to reveal the relationship between a specific disease and blood group type, meta-analyses have been published. Previously, the authors have studied the metabolic status, cell composition and coagulation profile of clinically healthy individuals for more than on 180,000 donations, that allowed to identify group-specific features for each blood group. This review presents generalized data on the association of such pathological conditions as coronary heart disease, thromboembolic complications, tumors of various localizations, inflammatory and destructive oral diseases, psychiatric and some infectious diseases with the presence or absence of antigenic determinants A and B. Carriers of blood group 0 (I) are generally more resistant to diseases, with the exception of H.pylori-associated gastrointestinal diseases. Carriers of «antigenic» blood groups A (II), B (III), AB (IV) are more susceptible to development of infectious, cardiovascular and cancer diseases. The presented data demonstrate clinical significance of the definition of group typing not only for selection of blood and its components during transfusion and transplantation, but also for diagnostics, determination of risk group and tactics for treatment patients with different nosologies.

China, the Crime of Aggression, and the International Criminal Court

2014 ◽  
Vol 5 (1) ◽  
pp. 94-122 ◽  
Author(s):  
Dan ZHU
Keyword(s):  
International Criminal Court ◽  
International Criminal ◽  
Criminal Court ◽  
Policy Preference ◽  
State Party ◽  
Legal Perspective ◽  
To Come ◽  
Definition Of

At the Kampala Review Conference in 2010, the adoption of the amendments to the Rome Statute laid the groundwork for the eventual prosecution of the crime of aggression. China, a non-State Party to the International Criminal Court, has articulated its concerns regarding the Court's jurisdiction over the crime of aggression in legal terms. This paper examines the Chinese concerns regarding the role of the Security Council in the determination of an act of aggression and the definition of aggression primarily from a legal perspective. It argues that China has hovered back and forth between two conflicting legal positions on these issues during different periods in history according to its policy preference. This paper also considers the concerns of China from a policy perspective before concluding that the crime of aggression should not be regarded as an insurmountable barrier preventing China's accession to the ICC in years to come.

scholarly journals ROLE OF APPLYING INNOVATIVE TECHNOLOGY " INVERTED LESSON» WHEN TEACHING A SECOND LANGUAGE AT A UNIVERSITY

2020 ◽  
Author(s):  
A.K. Murzaeva ◽  
Sh.K. Zikirova ◽  
S.R. Mergenbaeva
Keyword(s):  
Second Language ◽  
New Technologies ◽  
Cognitive Activity ◽  
Cultural Knowledge ◽  
Innovative Technology ◽  
Advantages And Disadvantages ◽  
The One ◽  
Definition Of ◽  
Independent Work

This article discusses the possibilities of using the innovative technology “inverted lesson” in combination with teaching in cooperation when teaching a second language at a university. The search for new technologies for training is due to the growing role of self-education in the concept of general cultural competencies of a modern specialist. Therefore, modern pedagogical technologies help students develop self-study skills. The advantages of the technology under study are found in an increase in the time for individual and independent work with students, in the ability to provide additional general cultural knowledge in parallel with the study of a certain thematic section on the one hand, as well as in the inclusion of students in active cognitive activity, the development of their independence on the other. The article shows the main approaches to the definition of the “inverted lesson” technology, gives its advantages and disadvantages, technical difficulties encountered in the implementation of the technology and, finally, the positive effect that can be achieved by using the “inverted lesson” technology in the classroom to study the second language among university students

scholarly journals Assessment of “maturity” of the taxpayer's internal control system for tax monitoring purposes

2021 ◽  
pp. 28-59
Author(s):  
Elena Vladimirovna Berezina ◽  
Anna Sergeevna Balandina ◽  
Ol'ga Svyatoslavovna Belomyttseva
Keyword(s):  
Control System ◽  
Internal Control ◽  
Control Procedure ◽  
Economic Entity ◽  
It Systems ◽  
Internal Control System ◽  
The Subject ◽  
The One ◽  
Definition Of

The internal control system is examined as a variety of internal control of an economic entity on the one hand, and as the foundation for transitioning towards tax monitoring on the other. Such approach allows assessing this structure from the perspective of taxpayers, as well as from the standpoint of implementation of public function of tax control. The object of this article is the process of improving internal control system of tax obligations by the taxpayer in the conditions of digitalization of tax administration. The subject of this article is the theoretical aspects of internal control as an administrative function, as well as comparative analysis of the Russian “internal control” system with the classical COSO model. The scientific novelty consists in comprehensive research of the internal control of tax obligations, determination of its essential characteristics,  and assessment of the consequences of formalization of requirements thereof, which led to the conclusion on transformation of the internal control of the taxpayer from the area of reputational merits of the economic entity and internal administration instruments to the subject of public control by tax authorities in tax monitoring processes. It remains to be seen whether state interference in such delicate sphere of activity of an economic entity as internal control is justified. The goal of this research consists in the analysis of the effective requirements of the Federal Tax Service of Russia from the perspective of possibility of their implementation by the particular taxpayers. The article provides the examples of assessment of certain components of the internal control system based on the criteria set by the Federal Tax Service of Russia. The author formulates the definition of control procedure, carries out classification of the aforementioned criteria; develops the examples of effective design of some controls; as well as presents the examples of assessment of IT systems from in the context of extended requirements of the Federal Tax Service of Russia.

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