scholarly journals Pathophysiology and Treatment of Pruritus in Elderly

2020 ◽  
Vol 22 (1) ◽  
pp. 174
Author(s):  
Bo Young Chung ◽  
Ji Young Um ◽  
Jin Cheol Kim ◽  
Seok Young Kang ◽  
Chun Wook Park ◽  
...  
Keyword(s):  
Skin Diseases ◽  
Unknown Origin ◽  
The Elderly ◽  
Common Symptom ◽  
Multiple Factors ◽  
Signaling Mechanisms ◽  
Novel Drugs ◽  
Neuropathic Pruritus ◽  
Chronic Pruritus

Pruritus is a relatively common symptom that anyone can experience at any point in their life and is more common in the elderly. Pruritus in elderly can be defined as chronic pruritus in a person over 65 years old. The pathophysiology of pruritus in elderly is still unclear, and the quality of life is reduced. Generally, itch can be clinically classified into six types: Itch caused by systemic diseases, itch caused by skin diseases, neuropathic pruritus, psychogenic pruritus, pruritus with multiple factors, and from unknown causes. Senile pruritus can be defined as a chronic pruritus of unknown origin in elderly people. Various neuronal mediators, signaling mechanisms at neuronal terminals, central and peripheral neurotransmission pathways, and neuronal sensitizations are included in the processes causing itch. A variety of therapies are used and several novel drugs are being developed to relieve itch, including systemic and topical treatments.

scholarly journals Correlation between temporomandibular disorder and quality of sleep in women

2016 ◽  
Vol 29 (3) ◽  
pp. 527-532
Author(s):  
Juliana de Paiva Tosato ◽  
Fabiano Politti ◽  
Marilia Barbosa Santos Garcia ◽  
Tabajara de Oliveira Gonzalez ◽  
Daniela Aparecida Biasotto-Gonzalez
Keyword(s):  
Analogue Scale ◽  
Temporomandibular Disorder ◽  
Cross Sectional Study ◽  
Common Symptom ◽  
Sectional Study ◽  
Quality Of Sleep ◽  
Cross Sectional ◽  
Multiple Factors ◽  
Pain Symptoms

Abstract Introduction: Temporomandibular Disorder (TMD) is caused by multiple factors and exhibits various symptoms. Its most common symptom is pain, a factor that can influence the quality of an individual's sleep. Objective: The aim of the present study was to assess the correlation between TMD and sleep. Methods: A cross-sectional study was conducted with 60 women, aged between 18 and 40 years, who had been diagnosed with TMD based on the Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD). Fonseca's anamnestic index (FAI) was used to classify the severity of the dysfunction. To complete the assessment, each volunteer was assessed using the visual analogue scale (VAS) for pain. They also responded to two questions related to their quality of sleep and the average hours of sleep per night. Results: The more severe the TMD, the fewer hours of sleep per night (r = -0.5663). In total, 63.33% of the volunteers reported not sleeping well. Concerning pain, the greater the VAS score, the less hours of sleep (r = -0.516) and the more severe the TMD. Conclusion: It was found that the severityof TMD was correlated with pain symptoms and the number of hours of sleep per night.

scholarly journals Clinico-epidemiological profile of palmoplantar dermatoses in northeast India

2021 ◽  
Vol 7 (6) ◽  
pp. 800
Author(s):  
Sana S. ◽  
Bijayanti Devi ◽  
Mrudula S.
Keyword(s):  
Skin Diseases ◽  
Cross Sectional Study ◽  
Northeast India ◽  
Outpatient Department ◽  
Common Symptom ◽  
Medical Sciences ◽  
Diagnostic Dilemma ◽  
Cross Sectional ◽  
Epidemiological Profile

<p class="abstract"><strong>Background:</strong> Palmoplantar dermatoses are skin diseases affecting palms and soles and are commonly seen in the dermatology practice. It can cause significant discomfort to the patients, affecting their daily activities and also is a diagnostic dilemma to the physician. To determine the clinico-epidemiological profile of palmoplantar dermatoses among patients attending the outpatient department (OPD).</p><p class="abstract"><strong>Methods:</strong> Hospital based cross sectional study carried out from September 2018 to August 2020 in patients attending outpatient department of dermatology in Regional Institute of Medical Sciences (RIMS) Hospital, Imphal, Manipur.<strong></strong></p><p class="abstract"><strong>Results:</strong> Of the total 200 patients, nearly half were males (50.5%). Most common age group involved was 26-45 years. Itching was the most common symptom (60%). Multiple lesions with palm alone involvement accounted for higher percentage with 39.5% followed by palmoplantar involvement. Most common palmoplantar dermatosis in the study was eczema with 23% followed by psoriasis (7.5%), dermatophytosis (7%), verruca vulgaris (6.5%), and keratolysis exfoliativa (6%).</p><p class="abstract"><strong>Conclusions:</strong> Eczema was the most common palmoplantar disorder followed by psoriasis. Diagnosis of palmoplantar dermatoses is important at the earliest for appropriate management which helps in improving the patient’s quality of life.</p><p class="abstract"> </p>

scholarly journals Chronic Pruritus Responding to Dupilumab—A Case Series

Medicines ◽  
2019 ◽  
Vol 6 (3) ◽  
pp. 72 ◽  
Author(s):  
Zhai ◽  
Savage ◽  
Qiu ◽  
Jin ◽  
Valdes-Rodriguez ◽  
...  
Keyword(s):  
Complete Resolution ◽  
Therapeutic Option ◽  
Case Series ◽  
Unknown Origin ◽  
Off Label ◽  
Uremic Pruritus ◽  
Disease States ◽  
Tertiary Center ◽  
Chronic Pruritus

Background: Chronic pruritus is defined as itch lasting for greater than six weeks. Pruritus is a burdensome manifestation of several internal and external disease states with a significant impact on quality of life. Dupilumab has shown promise in treating a number of conditions including atopic dermatitis (AD) and asthma. Its success in reducing pruritus in AD has generated interest regarding its potential application in other pruritic conditions, such as chronic pruritus of unknown origin, uremic pruritus, and pruigo nodularis. Methods: In this retrospective analysis, we present a series of 20 recalcitrant pruritus patients seen at a tertiary center treated with off-label dupilumab at standard AD dosing. Results: Dupilumab was successful at reducing itch in all treated patients, leading to complete resolution in 12/20 patients and an overall mean NRSi reduction of 7.55. Dupilumab was well tolerated with no significant adverse effects. Conclusions: Our case series suggests dupilumab may be a safe and efficacious therapeutic option in several pruritic conditions and demonstrates the need for further studies to better ascertain its place in the pruritus treatment armamentarium.

HUBUNGAN PERAN FAMILY CAREGIVER TERHADAP QUALITAS HIDUP LANSIA

2019 ◽  
Vol 11 (1) ◽  
pp. 51-56
Author(s):  
RIANI PRADARA JATI ◽  
Sekar Farah Nabila
Keyword(s):  
Quality Of Life ◽  
Family Caregiver ◽  
Random Sampling ◽  
Simple Random Sampling ◽  
The Elderly ◽  
Chi Square ◽  
The Poor ◽  
The Family

  Penempatan peran yang baik bagi Family Caregiver sangatlah membantu lansia dalam meningkatkah qualitas hidupnya, meningkatkan motivasi dalam menjalankan hidup Penelitian ini bertujuan Mengetahui hubungan peran Family Caregiver dalam pemenuhan qualitas hidup bagi lansia di Kelurahan Langenharjo Kabupaten Kendal. DesainPenelitianDeskriptifKorelasional menggunakan pendekatan Krosectional,tehnikSamplingStratified Simple Random Sampling dengan karakteristik heterogen, dari populasi mempunyai hak yang sama untuk diseleksi sebagai sampel teknik undianPengambilan data dengan menggunakan kuesioner yang telah diuji validitas dan reliabilitasnya. Uji statistik Chi-square, dengan taraf signifikasi 5%jumlah sampel pada penelitian ini 70 sampel pada Family Caregiver dari 213 populasi yang ada. Hasil penelitian dari 70 responden didapatkan Peran Family Caregiver tidak baik dengan qualitas hidup tidak baik 33 (47,1%), sedangkan Peran Family Caregiver kurang baik dengan qualitas hidup lansia baik 3 (4,3%). Untuk distribusi Peran Family Caregiver kurang baik dengan qualitas hidup lansia tidak baik sebanyak 6 responden (8,6%) sedangkan untuk distribusi Peran Family Caregiver kurang baik dengan qualitas hidup lansia baik sebanyak 23 responden (32,9%). Terakhir, untuk distribusi Peran Family Caregiver baik dengan qualitas hidup lansia tidak baik didapatkan hasil 2 responden (2, 9%) sedangkan untuk distribusi Peran Family Caregiver baik dengan qualitas hidup lansia baik didapatkan hasil 3 responden (4,3%)Menunjukkan nilai ρ value 0,001 (ρ < 0,05) berarti ada hubungan antara dukungan keluarga dengan kepatuhan lansia dalam keikutsertaan posyandu lansia. Disarankan kepada semua Family Cregiver lansia untuk mampu memahami pentingnya perhatian, dukungan bagi lansia dalammeningkatkan qualitas hidup yang lebih baik bagi lansia.   Kata kunci : Peran family caregiver, qualitas hidup, lansia.   ABSTRACT Placement of a good role for Family Caregiver is very helpful for the elderly to improve their quality of life, increase motivation in living life Research Objective: To know the relationship between the role of Family Caregiver in fulfilling quality of life for the elderly in Langenharjo Village, Kendal Regency. Descriptive Correlational Research Design uses a cross sectional approach, Sampling Stratified Simple Random Sampling technique with heterogeneous characteristics, from the population has the same right to be selected as a sample lottery technique Retrieving data using a questionnaire that has been tested for validity and reliability. Test Chi-square statistics, with a significance level of 5% the number of samples in this study 70 samples on the Family Caregiver from 213 populations. Results of the Study Of 70 respondents found the role of Family Caregiver was not good with poor quality of life 33 (47.1%) , while the role of the Family Caregiver is not good with the quality of life of a good elderly 3 (4.3%). For the distribution of the role of Family Caregiver is not good with the quality of life of the poor family as many as 6 respondents (8.6%) while for the distribution of the Role of Family Caregiver is not good with the quality of life of good elderly as many as 23 respondents (32.9%). Finally, the distribution of the Role of Family Caregiver with good quality of life for the poor is obtained by 2 respondents (2, 9%), while the distribution of the Role of Family Caregiver with good quality of life for the elderly is obtained by 3 respondents (4.3%). 0.001 (ρ <0.05) means that there is a relationship between family support and the compliance of the elderly in the participation of the elderly posyandu. It is recommended to all elderly Cregiver families to be able to understand the importance of attention, support for the elderly in improving the quality of life better for the elderly   Keywords: Role of Family Caregiver, Quality of Life, Elderly

PHYSICAL, SOCIAL ACTIVITIES AND QUALITY OF LIFE OF THE ELDERLY LIVING IN TRUONG AN WARD, HUE CITY IN 2016

2019 ◽  
pp. 55-62
Author(s):  
Vuong Diem Khanh Doan ◽  
Ngoc Minh Chau Ho ◽  
Thi Van Ngo ◽  
Thi Bao Nga Phan ◽  
Thi Hong Phan Nguyen
Keyword(s):  
Quality Of Life ◽  
The Elderly ◽  
Total Sample ◽  
Cross Sectional Study ◽  
Physical Activities ◽  
Social Activities ◽  
Sectional Study ◽  
Cross Sectional ◽  
Elderly Living

Background: Vietnam is entering the stage of aging population; as a result, the quality of life (QOL) of the elderly is really a matter of concern. There is a great deal of research on the quality of life of the elderly while Vietnam witnesses a lack of research on this topic, especially on how physical and social activities have impact on QOL of the elderly. Objectives: (1) To describe the situation of participation in physical, social activities and QOL of the elderly residing in Truong An Ward, Hue city. (2) To examine the association between physical, social activities and QOL among participants. Methodology: This study used cross-sectional study design. A total sample of 420 people aged 60 and above in Truong An Ward, Hue city were interviewd. The SF36 was used to measure the QOL of participants. Results: Percentage of the elderly taking part in physical activity were 66%. 49% reported having the habit of taking part in social activities. The majority of the elderly get their QOL level in three health fields, namely physical, mental and general health at above average. (56.0, 60.7 and 60.8 respectively). There were significant associations between physical activities, social activities and QOL among participants. Conclusion: The percentage of the elderly taking part in physical and social activities were still low. Besides, QOL of the elderly at the research location was not really high. It’s important to encourage the elderly taking part in physical and social activities to improve their quality of life. Key words: Physical activities, social activities, QOL, the elderly

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