scholarly journals Electric Scooter-Related Injuries: A New Epidemic in Orthopedics

2021 ◽  
Vol 10 (15) ◽  
pp. 3283
Author(s):  
Alexandre Coelho ◽  
Pablo Feito ◽  
Laura Corominas ◽  
Juan Francisco Sánchez-Soler ◽  
Daniel Pérez-Prieto ◽  
...  
Keyword(s):  
Prospective Observational Study ◽  
Demographic Data ◽  
Upper Limbs ◽  
Injury Patterns ◽  
Electric Scooter ◽  
The Mean ◽  
One Year ◽  
Accident Mechanism ◽  
Type Of Injury ◽  
Time Type

Background: The use of electric scooters has increased considerably as they are an accessible means of transportation. The number of injuries from falls and collisions has risen significantly. Therefore, the aim of the study was to describe demographics injury patterns of electric scooter accidents produced over one year. Methods: A prospective observational study of electric scooter- related injuries presented in the emergency room from May 2019 until May 2020. The inclusion criteria was based on the direct cause of injury produced while an electric scooter was in use. Demographic data, the use of a helmet or the lack thereof, accident mechanism, injury time, type of injury produced, and the treatment applied were collected. Results: Over the study period, 397 patients were identified with a total of 422 injuries. The mean age was 30.8 years, with 12.6% of patients being minors. The patients mainly presented in evening hours and in summertime at the emergency department. Of the total injuries seen, 46.9% were fractures. Some 25% of the total cases required surgery. Only 19% of the riders wore a helmet at the time of the accident. Most of the fractures were to the upper limbs (62.6%). There was a greater incidence of radius fractures. Conclusion: Injuries incurred while using electric scooters are an emerging phenomenon, despite existing regulations. In this study, most injuries occurred in young men and were due to falls from the vehicle. Nearly half of those injuries were fractures to the upper limbs. Surprisingly, 50% of the fractures required surgery.

scholarly journals Predictive Factors of the Adherence to Real-Time Continuous Glucose Monitoring Sensors: A Prospective Observational Study (PARCS STUDY)

2020 ◽  
pp. 193229682093920
Author(s):  
Takashi Murata ◽  
Akio Kuroda ◽  
Munehide Matsuhisa ◽  
Masao Toyoda ◽  
Moritsugu Kimura ◽  
...  
Keyword(s):  
Continuous Glucose Monitoring ◽  
Prospective Observational Study ◽  
Insulin Infusion ◽  
Glucose Monitoring ◽  
Self Monitoring ◽  
Related Quality ◽  
The Mean ◽  
One Year

Background: Information about factors related to better adherence to continuous glucose monitoring (CGM) sensor adherence is quite limited. Materials and Methods: Forty-six participants with type 1 diabetes using continuous subcutaneous insulin infusion (CSII) without CGM were recruited. The participants’ characteristics and diabetes-related quality of life (QOL) were evaluated at baseline and one year after starting to use CGM. Participants wearing the sensor for ≥60% of the time were considered as adherent. Results: The mean age of the 46 participants was 44.1 ± 15.0 years old and the mean glycohemoglobin (HbA1c) was 7.7 ± 1.0%; 60.9% of the participants were classified as adherent. The duration of using CSII was longer in the adherent group, and the degree of diabetic retinopathy was significantly different. There were no significant differences in age, frequency of self-monitoring of blood glucose, or Hypoglycemia Fear Survey (HFS-B for behavior, HFS-W for worry) score at baseline between the adherent and nonadherent groups. The Problem Areas in Diabetes (PAID) score at baseline was significantly higher and the total CSII-QOL score at baseline was significantly lower in the adherent group. The usage of dual-wave bolus was significantly increased in the adherent group (34.6%-61.5%, P = .016), but not in the nonadherent group (33.3%-33.3%, P > .999). The HbA1c level showed a significant improvement in the adherent group (7.8%-7.3%, P < .001), but not in the nonadherent group (7.5%-7.2%, P = .102). Conclusions: Higher adherence to CGM sensors may be associated with a heavier emotional burden of diabetes and a worse QOL in relation to CSII at baseline.

scholarly journals Characteristics and Injury Patterns in Electric-Scooter Related Accidents—A Prospective Two-Center Report from Germany

2020 ◽  
Vol 9 (5) ◽  
pp. 1569 ◽  
Author(s):  
Philipp Störmann ◽  
Alexander Klug ◽  
Christoph Nau ◽  
René D. Verboket ◽  
Max Leiblein ◽  
...  
Keyword(s):  
Emergency Department ◽  
Hospital Treatment ◽  
Body Region ◽  
Injury Patterns ◽  
Center Report ◽  
Electric Scooter ◽  
Valid Data ◽  
The Subject ◽  
The Mean ◽  
Serious Injuries

Since the introduction of rental E-scooters in Germany in mid-June 2019, the safety of this new means of transport has been the subject of extensive public debate. However, valid data on injuries and usage habits are not yet available. This retrospective two-center study included a total of 76 patients who presented to the emergency department following E-scooter-related accidents. The mean age was 34.3 ± 12.4 years and 69.7% of the patients were male. About half of the patients were admitted by ambulance (42.1%). Fractures were found in 48.6% of patients, and 27.6% required surgical treatment due to a fracture. The upper extremities were the most commonly affected body region, followed by injuries to the lower extremity and to the head and face. Only one patient had worn a helmet. In-hospital treatment was necessary for 26.3% of the cases. Patients presented to the emergency department mainly during the weekend and on-call times. This is the first report on E-scooter-related injuries in Germany. Accidents with E-scooters can cause serious injuries and, therefore, represent a further burden to emergency departments. The use of E-scooters appears to be mostly recreational, and the rate of use of protective gear is low.

scholarly journals The NIMO Scandinavian Study: A Prospective Observational Study of Iron Isomaltoside Treatment in Patients with Iron Deficiency

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Svein Oskar Frigstad ◽  
Anne Haaber ◽  
Antal Bajor ◽  
Jan Fallingborg ◽  
Per Hammarlund ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Prospective Observational Study ◽  
Intravenous Iron ◽  
Lower Probability ◽  
Significant Treatment ◽  
The Mean ◽  
Clinically Significant ◽  
High Doses ◽  
One Year ◽  
Over Time

Background. Intravenous iron allows for efficient and well-tolerated treatment in iron deficiency and is routinely used in diseases of the gastrointestinal tract. Objective. The aims of this study were to determine the probability of relapse of iron deficiency over time and to investigate treatment routine, effectiveness, and safety of iron isomaltoside. Methods. A total of 282 patients treated with iron isomaltoside were observed for two treatments or a minimum of one year. Results. Out of 282 patients, 82 had Crohn’s disease and 67 had ulcerative colitis. Another 133 patients had chronic blood loss, malabsorption, or malignancy. Patients who received an iron isomaltoside dose above 1000 mg had a 65% lower probability of needing retreatment compared with those given 1000 mg. A clinically significant treatment response was shown, but in 71/191 (37%) of patients, anaemia was not corrected. The mean dose given was 1100 mg, lower than the calculated total iron need of 1481 mg. Adverse drug reactions were reported in 4% of patients. Conclusion. Iron isomaltoside is effective with a good safety profile, and high doses reduce the need for retreatment over time. Several patients were anaemic after treatment, indicating that doses were inadequate for full iron correction. This trial is registered with NCT01900197.

scholarly journals Clinical profile of congenital limb anomalies in neonates

2018 ◽  
Vol 5 (2) ◽  
pp. 299 ◽  
Author(s):  
Yogesh N. Parikh ◽  
Mitul B. Kalathia ◽  
Dhanya Soodhana
Keyword(s):  
Prospective Observational Study ◽  
Demographic Data ◽  
Epidemiological Studies ◽  
Birth Prevalence ◽  
Limb Anomalies ◽  
History Of ◽  
Limb Malformations ◽  
Congenital Limb ◽  
The Mean ◽  
Insight Into

Background: Reported birth prevalence of congenital limb defects vary from country to country. Epidemiological studies permit the timely detection of trends in congenital limb anomalies and the associations with other birth defects. The objective of this study was to know the prevalence and the variety of congenital limb anomalies and their association with other anomalies.Methods: A prospective observational study in which all newborns reported to the neonatal department were surveyed to find out the incidence, diversity and association of limb anomalies. Age of the mother, risk factors and other demographic data of the newborns was analyzed. Babies born less than 28 weeks were excluded from the study.Results: The prevalence was 6.34 per thousand live births. The majority of the neonates were term babies and female. 28 % of the babies were born out of consanguineous marriage. The mean age of the mother was 25. Median parity was 1. 9.52 % of the babies had a history of anomaly in the sibling. 4.76 % had a history of still birth. The most common congenital anomaly was congenital talipo equino varus. The other congenital limb anomalies observed were polydactyly, syndactyly, bifid thumb and absence of the radius. There were multiple congenital anomalies in 28.57 % of the babies.Conclusions: The study has given us an insight into the variety of congenital limb malformations and also into the possible etiological factors. A study done on a larger population would probably help us assess the incidence and pattern of occurrence of limb anomalies and help us counsel the parents. 

scholarly journals Prevalence of Asymptomatic Brucellosis in Children 7 to 12 Years Old

2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Mohammad Aghaali ◽  
Siamak Mohebi ◽  
Hosein Heydari
Keyword(s):  
Demographic Data ◽  
Clinical Manifestations ◽  
Asymptomatic Infection ◽  
Short Term ◽  
Disease Symptoms ◽  
Blood Samples ◽  
Asymptomatic Children ◽  
The Mean ◽  
One Year

Background. Brucellosis is one of the most common diseases of humans and animals and its clinical manifestations differ from asymptomatic infection to chronic illness associated with recurrence of symptoms. This study aimed to evaluate the prevalence of brucellosis in asymptomatic children 7 to 12 years old in Kahak, Iran.Methods. In this study, 186 children 7 to 12 years old were evaluated. Demographic data and exposure to the brucellosis agent were recorded and blood samples for the Wright, Coombs, and 2ME tests were collected. All the study subjects were followed up for one year about the appearance of symptoms.Results. The mean age was 10 ± 1.72 years and 51% were boys. Family history was positive for brucellosis in 15% of children. A total of 8 children were brucellosis seropositive and, in subsequent follow-up, 6 of them showed the disease symptoms.Conclusion. This study showed that approximately 4.3% of children in endemic areas can have asymptomatic brucellosis and many of these children may be symptomatic in short term.

scholarly journals FRI0266 THE REAL-WORLD EFFICACY OF THE 2015 EULAR/ACR RECOMMENDATIONS FOR THE MANAGEMENT OF POLYMYALGIA RHEUMATICA WITH ADDITIONAL TOCILIZUMAB THERAPY

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 717.2-718
Author(s):  
M. Yamamura
Keyword(s):  
Adverse Effects ◽  
Real World ◽  
Polymyalgia Rheumatica ◽  
Demographic Data ◽  
Age At Onset ◽  
Disease Recurrence ◽  
The Real ◽  
The Mean ◽  
One Year ◽  
Drug Free

Background:A Part of patients with polymyalgia rheumatica (PMR) are refractory to the 2015 EULAR/ACR algorism for the management of PMR. Recent reports have demonstrated that tocilizumab (TCZ) may be efficacious for refractory and relapsing PMR.Objectives:To determine the real-world efficacy of the 2015 EULAR/ACR algorism for the management of PMR plus introduction of TCZ for refractory and relapsing PMR.Methods:Patients who had been diagnosed with PMR according to the 2012 EULAR/ACR provisional classification criteria for PMR were recruited in the study. Registered variables included demographic data, disease characteristics, prednisolone (PSL) dosage and duration, addition of methotrexate (MTX) and TCZ, adverse effects, and clinical outcomes.Results:There were 101 patients who had originally diagnosed as PMR (50 males and 65 females) and followed up for at least one year; the mean ± SD age at onset was 73 ±11 years at onset, with the mean observational period being 44 ± 26 months. Their treatments were initiated with PSL of 15.5 ± 4.3 mg/day. 41 patients experienced disease recurrence after 9.6 ± 6.7 months (median 9 month) of GC therapy, while receiving PSL at 5 ± 4.5 mg/day (3.7 mg/day). Baseline factors that were associated with relapse in our cohort were higher-grade thrombocytosis and higher-dose of initial GC by multivariate analysis. In 30 of the 41 patients who failed GC monotherapy, MTX was added. Five patients reached GC-free remission, but 25 patients failed GC tapering. In such refractory patients to a combination of GC plus MTX, 8 patients agreed to add TCZ therapy, and 5 of them reached drug-free remission. At present, 67 of the total 101 patients maintained drug-free remission, but most others were still receiving low-dose GC and/or MTX (n=17). No significant adverse effects did not occur during therapy, except for GC-related adverse effects such as diabetes, dyslipidemia and osteoprotic fractures.Conclusion:Our experience indicated that there is notable heterogeneity across PMR patients in terms of drug response, and the patients with severe inflammation, e.g. thrombocytosis, may need higher-dose of initial GC and addition of biologics such as TCZ on the 2015 EULAR/ACR algorism.Acknowledgments:NoneDisclosure of Interests:None declared

scholarly journals CT Score as a Mainstay of Tocilizumab Treatment in COVID-19

2021 ◽  
Vol 6 (09) ◽  
pp. 554-559
Author(s):  
Vedrana Terkes ◽  
Anela Tolic ◽  
Miro Morovic
Keyword(s):  
Prospective Observational Study ◽  
Clinical Status ◽  
Laboratory Data ◽  
Mean Value ◽  
Lung Damage ◽  
Mean Values ◽  
Inflammatory Parameters ◽  
Administration Time ◽  
The Mean ◽  
One Year

Background: After one year of numerous clinical trials, the position of tocilizumab in the treatment of COVOD-19 patients is not yet stable. Methods: In this small prospective observational study, we recruited patients with severe and critical COVID-19 with a rapid deterioration of their clinical status. Demographic, clinical, CT findings and laboratory data were collected prior to the decision to administer tocilizmab. Results: 33 patients were included between March 2020 and February 2021 11 (33.3%) of patients died, with the median of 22.5 (9-35) days (p<0.05). Compared with the survivors, the patients who died were significantly older, with the mean age of 72.5 years vs 61.3 years, respectively. Also, the mean CT scores in the patients who died were significantly higher than in the survivors, with the mean value of 22.7 vs 17.3 (p<0.05). In addition, there was also a difference in the mean values of inflammatory parameters, which were generally higher in non-survivors. Conclusion: In this small exploratory analysis of 33 patients with severe or critical COVID-19, treated with tocilizumab we did not obtain neither a significant reduction of ICU admission neither of mortality. The high CT grade of lung damage has shown to be the only independent prognostic factor of clinical outcome, regardless of administration time or criteria of tocilizumab use.

Innocent Children in the Syrian Civil War

2019 ◽  
Vol 30 (02) ◽  
pp. 215-219
Author(s):  
Mehmet Emin Çelikkaya ◽  
Ahmet Atıcı ◽  
Çigdem EL ◽  
Bülent Akçora
Keyword(s):  
Civil War ◽  
Demographic Data ◽  
Mortality And Morbidity ◽  
War Injuries ◽  
Syrian Civil War ◽  
History Of ◽  
The Mean ◽  
War Victims ◽  
Trauma Score ◽  
Type Of Injury

Abstract Introduction Our aim is to present the clinical and surgical characteristics of the children affected by the Syrian civil war. Materials and Methods Medical records were reviewed retrospectively for Syrian war victims between the ages of 0 and 18 who were brought to the emergency department of the Education and Research Hospital between March 2011 and March 2019. Each patient was evaluated with respect to demographic data (gender, age), type of injury, history of operations in Syria, injured organ(s), accompanying traumas and the mortality and trauma score. Results The majority of our study population of 147 patients were male (108/147, 73.46%), and 39 of the total were girls (26.53%). The mean age of the patients was 9 (7.5 ± 4). The mean age of the girls was 8.5 (range: 7 months to 16 years), and the mean age of the boys was 9.2 (4 months to 17 years). Seventeen patients who had abdominal surgery in Syria were operated on again after clinical and radiological observations. A total of 83 patients were operated on in Turkey. For 66 of those patients, the operation in Turkey was their first surgery on their war injuries. Seventeen patients were operated on in Syria but needed surgery again in Turkey. Conclusion War affects not only the battlefield, but also the neighboring countries in many aspects such as medical, social, and economic. Hollow organ injuries are the most common intraabdominal pathologies. Delayed intervention is associated with increase mortality and morbidity.

scholarly journals Evaluation of Risk Factors for Exchange Range Hyperbilirubinemia in Neonates from Eastern Part of Nepal

2021 ◽  
Vol 41 (1) ◽  
pp. 67-72
Author(s):  
Sunil Kumar Yadav ◽  
Arun Giri ◽  
Bbita Khanal
Keyword(s):  
Risk Factors ◽  
Gestational Age ◽  
Exchange Transfusion ◽  
Prospective Observational Study ◽  
Neonatal Period ◽  
P Value ◽  
Abo Incompatibility ◽  
Rh Incompatibility ◽  
The Mean ◽  
One Year

Introduction: Neonatal hyperbilirubinemia continues to be the commonest cause of nursery and NICU admissions and readmissions in the neonatal period worldwide. Although most cases are physiological, toxic levels of un-conjugated bilirubin can lead to acute and chronic bilirubin encephalopathy. Hence, this study aimed to study the risk factors for exchange range hyperbilirubinemia in neonates. Methods: This was a hospital-based prospective observational study conducted in a teaching and referral NICU over a period of one year from July 2019 to August 2020. All neonates with diagnosis of hyperbilirubinemia requiring double volume exchange transfusion were included in the study. Risk factors for significant hyperbilirubinemia were analysed with descriptive statistics. P-value of < 0.05 was considered significant wherever applicable. Results: The mean gestational age and birth weight were 38.06 ± 2.13wks and 2611.72 ± 389.39 gm respectively. Fifteen percent of the babies (162) developed hyperbilirubinemia and 28 (17.3%) required double volume exchange transfusion. Among neonates requiring exchange transfusion, 17 were females and 11 were males. Among 28 babies who required DVET, 20 (71.4%) were SGA. ABO incompatibility was present in 14 (50.0%) neonates and Rh incompatibility in 13 (46.4%) neonates. ABO along with Rh incompatibility was present in eight (28.6%) neonates. DCT was positive in six neonates with ABO incompatibility and nine neonates in Rh incompatibility. G6PD deficiency was present in four (14.3%) neonates. Conclusions: The most important risk factors identified were small for gestational age, ABO and Rh incompatibility followed by oxytocin use and sibling treated for jaundice.

scholarly journals Spirometry Function after Decortication for Chronic Pleural Empyema: A Retrospective Study

2020 ◽  
Author(s):  
Subhash Minda ◽  
Lata Khatnani Koneru ◽  
Nimish Rai
Keyword(s):  
Retrospective Study ◽  
Pulmonary Function ◽  
Postoperative Period ◽  
Demographic Data ◽  
Pleural Empyema ◽  
Forced Expiratory Volume ◽  
Repeated Measure ◽  
The Mean ◽  
Trapped Lung ◽  
One Year

Introduction: Chronic Pleural Empyema (CPE) is a major medical concern. It gives rise to “trapped lung” due to the thickened pleural peel. This results in impairment of pulmonary function. The treatment of choice for CPE is open thoracotomy decortication. Aim: To evaluate changes in Pulmonary Function Test (PFT) in an immediate postoperative period of decortication for CPE. Materials and Methods: A retrospective study was conducted in 25 patients who had undergone decortication for CPE in the last one year (from October 2018 to September 2019) were included. Baseline clinical and demographic data were collected. Duration of ICU stay, hospital stay and complications were reviewed. In Preoperative period Forced Vital Capacity (FVC) and Forced Expiratory Volume In First Second (FEV1) was investigated. It was again repeated after 3 and 6 months of postoperative period. Preoperative and postoperative data at 3rd and 6th month were analysed. Percentage change in PFT was assessed. Repeated measure ANOVA were used for statistical analysis. Results: Preoperatively the mean FVC was 2.09 L (56.63%) and the mean FEV1 was 1.82 L (60.26%). The mean FVC, 3 months after surgery was 2.27 L (61.52%) and after 6 months was 2.53 L (68.56%). The mean FEV1, 3 months after surgery was 1.92 L (63.58%) and after 6 months was 2.17 L (71.58%). Spirometry values of FEV1 and FVC improved at 3rd and 6th month, postoperatively. Improvement in these Spirometric values after 6 months was quantified statistically significant. Conclusion: Decortication for CPE resulted in progressive improvement in spirometry values in a follow-up period of 3 and 6 months.

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