scholarly journals Metal Nanoparticles and Carbon-Based Nanomaterials for Improved Performances of Electrochemical (Bio)Sensors with Biomedical Applications

Materials ◽  
2021 ◽  
Vol 14 (21) ◽  
pp. 6319
Author(s):  
Luminita Fritea ◽  
Florin Banica ◽  
Traian Octavian Costea ◽  
Liviu Moldovan ◽  
Luciana Dobjanschi ◽  
...  
Keyword(s):  
Metal Nanoparticles ◽  
Real Time ◽  
High Surface ◽  
Hybrid Nanocomposites ◽  
Analyte Molecule ◽  
Early Detection Of Disease ◽  
Gold Silver ◽  
Wide Range ◽  
Carbon Based Nanomaterials ◽  
Carbon Based

Monitoring human health for early detection of disease conditions or health disorders is of major clinical importance for maintaining a healthy life. Sensors are small devices employed for qualitative and quantitative determination of various analytes by monitoring their properties using a certain transduction method. A “real-time” biosensor includes a biological recognition receptor (such as an antibody, enzyme, nucleic acid or whole cell) and a transducer to convert the biological binding event to a detectable signal, which is read out indicating both the presence and concentration of the analyte molecule. A wide range of specific analytes with biomedical significance at ultralow concentration can be sensitively detected. In nano(bio)sensors, nanoparticles (NPs) are incorporated into the (bio)sensor design by attachment to the suitably modified platforms. For this purpose, metal nanoparticles have many advantageous properties making them useful in the transducer component of the (bio)sensors. Gold, silver and platinum NPs have been the most popular ones, each form of these metallic NPs exhibiting special surface and interface features, which significantly improve the biocompatibility and transduction of the (bio)sensor compared to the same process in the absence of these NPs. This comprehensive review is focused on the main types of NPs used for electrochemical (bio)sensors design, especially screen-printed electrodes, with their specific medical application due to their improved analytical performances and miniaturized form. Other advantages such as supporting real-time decision and rapid manipulation are pointed out. A special attention is paid to carbon-based nanomaterials (especially carbon nanotubes and graphene), used by themselves or decorated with metal nanoparticles, with excellent features such as high surface area, excellent conductivity, effective catalytic properties and biocompatibility, which confer to these hybrid nanocomposites a wide biomedical applicability.

scholarly journals Nanotheranostic Carbon Dots as an Emerging Platform for Cancer Therapy

2020 ◽  
Vol 1 (1) ◽  
pp. 58-77
Author(s):  
Sumiya Adrita ◽  
Khandaker Tasnim ◽  
Ji Ryu ◽  
Shazid Sharker
Keyword(s):  
Cancer Treatment ◽  
Carbon Dots ◽  
High Surface ◽  
High Surface Area ◽  
Volume Ratio ◽  
Biomedical Sciences ◽  
Diagnosis And Therapy ◽  
Low Dimensional ◽  
Carbon Based Nanomaterials ◽  
Carbon Based

Cancer remains one of the most deadly diseases globally, but carbon-based nanomaterials have the potential to revolutionize cancer diagnosis and therapy. Advances in nanotechnology and a better understanding of tumor microenvironments have contributed to novel nanotargeting routes that may bring new hope to cancer patients. Several low-dimensional carbon-based nanomaterials have shown promising preclinical results; as such, low-dimensional carbon dots (CDs) and their derivatives are considered up-and-coming candidates for cancer treatment. The unique properties of carbon-based nanomaterials are high surface area to volume ratio, chemical inertness, biocompatibility, and low cytotoxicity. It makes them well suited for delivering chemotherapeutics in cancer treatment and diagnosis. Recent studies have shown that the CDs are potential applicants in biomedical sciences, both as nanocarriers and nanotransducers. This review covers the most commonly used CD nanoparticles in nanomedicines intended for the early diagnosis and therapy of cancer.

scholarly journals Application of Nanostructured Carbon-Based Electrochemical (Bio)Sensors for Screening of Emerging Pharmaceutical Pollutants in Waters and Aquatic Species: A Review

Nanomaterials ◽  
2020 ◽  
Vol 10 (7) ◽  
pp. 1268 ◽  
Author(s):  
Álvaro Torrinha ◽  
Thiago M. B. F. Oliveira ◽  
Francisco W.P. Ribeiro ◽  
Adriana N. Correia ◽  
Pedro Lima-Neto ◽  
...  
Keyword(s):  
Carbon Nanomaterials ◽  
Low Cost ◽  
High Surface ◽  
High Surface Area ◽  
Aquatic Species ◽  
Transfer Rates ◽  
Production Methods ◽  
Pharmaceutical Pollutants ◽  
Carbon Based Nanomaterials ◽  
Carbon Based

Pharmaceuticals, as a contaminant of emergent concern, are being released uncontrollably into the environment potentially causing hazardous effects to aquatic ecosystems and consequently to human health. In the absence of well-established monitoring programs, one can only imagine the full extent of this problem and so there is an urgent need for the development of extremely sensitive, portable, and low-cost devices to perform analysis. Carbon-based nanomaterials are the most used nanostructures in (bio)sensors construction attributed to their facile and well-characterized production methods, commercial availability, reduced cost, high chemical stability, and low toxicity. However, most importantly, their relatively good conductivity enabling appropriate electron transfer rates—as well as their high surface area yielding attachment and extraordinary loading capacity for biomolecules—have been relevant and desirable features, justifying the key role that they have been playing, and will continue to play, in electrochemical (bio)sensor development. The present review outlines the contribution of carbon nanomaterials (carbon nanotubes, graphene, fullerene, carbon nanofibers, carbon black, carbon nanopowder, biochar nanoparticles, and graphite oxide), used alone or combined with other (nano)materials, to the field of environmental (bio)sensing, and more specifically, to pharmaceutical pollutants analysis in waters and aquatic species. The main trends of this field of research are also addressed.

Carbon Nanomaterial-Based Drug Sensing Platforms Using State-of-the-Art Electroanalytical Techniques

2020 ◽  
Vol 16 ◽  
Author(s):  
S. Irem Kaya ◽  
Ahmet Cetinkaya ◽  
Sibel A. Ozkan
Keyword(s):  
Carbon Nanomaterials ◽  
Electrochemical Sensors ◽  
High Surface ◽  
Electrochemical Techniques ◽  
Functional Materials ◽  
Drug Analysis ◽  
Electrochemical Analysis ◽  
Research Subjects ◽  
Carbon Based Nanomaterials ◽  
Carbon Based

Background: Currently, nanotechnology and nanomaterials are considered as the most popular and outstanding research subjects in scientific fields ranging from environmental studies to drug analysis. Carbon nanomaterials such as carbon nanotubes, graphene, carbon nanofibers etc. and non-carbon nanomaterials such as quantum dots, metal nanoparticles, nanorods etc. are widely used in electrochemical drug analysis for sensor development. Main aim of drug analysis with sensors is developing fast, easy to use and sensitive methods. Electroanalytical techniques such as voltammetry, potentiometry, amperometry etc. which measure electrical parameters such as current or potential in an electrochemical cell are considered economical, highly sensitive and versatile techniques. Methods: Most recent researches and studies about electrochemical analysis of drugs with carbon-based nanomaterials were analyzed. Books and review articles about this topic were reviewed. Results: The most significant carbon-based nanomaterials and electroanalytical techniques were explained in detail. In addition to this; recent applications of electrochemical techniques with carbon nanomaterials in drug analysis was expressed comprehensively. Recent researches about electrochemical applications of carbon-based nanomaterials in drug sensing were given in a table. Conclusion: Nanotechnology provides opportunities to create functional materials, devices and systems using nanomaterials with advantageous features such as high surface area, improved electrode kinetics and higher catalytic activity. Electrochemistry is widely used in drug analysis for pharmaceutical and medical purposes. Carbon nanomaterials based electrochemical sensors are one of the most preferred methods for drug analysis with high sensitivity, low cost and rapid detection.

scholarly journals Carbon-Based Electric Double Layer Capacitors for Water Desalination

2010 ◽  
Author(s):  
Batya A. Fellman ◽  
Muataz Atieh ◽  
Evelyn N. Wang
Keyword(s):  
Electrode Materials ◽  
Salt Water ◽  
High Surface ◽  
High Surface Area ◽  
Water Desalination ◽  
Electrode Geometry ◽  
Capacitive Deionization ◽  
Water Stream ◽  
Carbon Based Nanomaterials ◽  
Carbon Based

In capacitive deionization (CDI), salt water is passed through two polarized electrodes, whereby the salt is adsorbed onto the electrode surface and removed from the water stream. This approach has received renewed interest for water desalination due to the development of new high-surface area carbon-based nanomaterials. However, there is currently limited understanding as to how electrode geometry, surface properties, and capacitance affect ion capture. In this work, we experimentally investigate various standard carbon-based electrode materials, including activated carbon and carbon cloths, as well as microfabricated silicon structures for CDI. Electrochemical characterization through cyclic voltammetry was used to determine the electrochemical properties of each material. In addition, a mini-channel test cell was fabricated to perform parametric studies on ion capture. By controlling electrode geometry and chemistry in these studies, the work helps elucidate transport mechanisms and provide insight into the design of optimal materials for capacitive deionization.

scholarly journals Carbon Nanomaterials: Synthesis, Functionalization and Sensing Applications

Nanomaterials ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 967
Author(s):  
Giorgio Speranza
Keyword(s):  
Carbon Nanomaterials ◽  
Carbon Quantum Dots ◽  
High Specific Surface Area ◽  
Design And Synthesis ◽  
Sensing Applications ◽  
Wide Range ◽  
Recent Developments ◽  
Carbon Based Nanomaterials ◽  
Inorganic Molecules ◽  
Carbon Based

Recent advances in nanomaterial design and synthesis has resulted in robust sensing systems that display superior analytical performance. The use of nanomaterials within sensors has accelerated new routes and opportunities for the detection of analytes or target molecules. Among others, carbon-based sensors have reported biocompatibility, better sensitivity, better selectivity and lower limits of detection to reveal a wide range of organic and inorganic molecules. Carbon nanomaterials are among the most extensively studied materials because of their unique properties spanning from the high specific surface area, high carrier mobility, high electrical conductivity, flexibility, and optical transparency fostering their use in sensing applications. In this paper, a comprehensive review has been made to cover recent developments in the field of carbon-based nanomaterials for sensing applications. The review describes nanomaterials like fullerenes, carbon onions, carbon quantum dots, nanodiamonds, carbon nanotubes, and graphene. Synthesis of these nanostructures has been discussed along with their functionalization methods. The recent application of all these nanomaterials in sensing applications has been highlighted for the principal applicative field and the future prospects and possibilities have been outlined.

scholarly journals Porous Carbon-Based Supercapacitors Directly Derived from Metal–Organic Frameworks

Materials ◽  
2020 ◽  
Vol 13 (18) ◽  
pp. 4215 ◽  
Author(s):  
Hyun-Chul Kim ◽  
Seong Huh
Keyword(s):  
Porous Materials ◽  
Electrode Materials ◽  
High Surface ◽  
Metal Organic Frameworks ◽  
Metal Species ◽  
Porous Carbons ◽  
Redox Active ◽  
Wide Range ◽  
Metal Organic ◽  
Carbon Based

Numerously different porous carbons have been prepared and used in a wide range of practical applications. Porous carbons are also ideal electrode materials for efficient energy storage devices due to their large surface areas, capacious pore spaces, and superior chemical stability compared to other porous materials. Not only the electrical double-layer capacitance (EDLC)-based charge storage but also the pseudocapacitance driven by various dopants in the carbon matrix plays a significant role in enhancing the electrochemical supercapacitive performance of porous carbons. Since the electrochemical capacitive activities are primarily based on EDLC and further enhanced by pseudocapacitance, high-surface carbons are desirable for these applications. The porosity of carbons plays a crucial role in enhancing the performance as well. We have recently witnessed that metal–organic frameworks (MOFs) could be very effective self-sacrificing templates, or precursors, for new high-surface carbons for supercapacitors, or ultracapacitors. Many MOFs can be self-sacrificing precursors for carbonaceous porous materials in a simple yet effective direct carbonization to produce porous carbons. The constituent metal ions can be either completely removed during the carbonization or transformed into valuable redox-active centers for additional faradaic reactions to enhance the electrochemical performance of carbon electrodes. Some heteroatoms of the bridging ligands and solvate molecules can be easily incorporated into carbon matrices to generate heteroatom-doped carbons with pseudocapacitive behavior and good surface wettability. We categorized these MOF-derived porous carbons into three main types: (i) pure and heteroatom-doped carbons, (ii) metallic nanoparticle-containing carbons, and (iii) carbon-based composites with other carbon-based materials or redox-active metal species. Based on these cases summarized in this review, new MOF-derived porous carbons with much enhanced capacitive performance and stability will be envisioned.

Graphene and carbon-based nanomaterials as highly efficient adsorbents for oils and organic solvents

2016 ◽  
Vol 5 (1) ◽  
Author(s):  
Shu Wan ◽  
Hengchang Bi ◽  
Litao Sun
Keyword(s):  
Organic Solvents ◽  
High Surface ◽  
High Surface Area ◽  
Three Dimensional ◽  
Surface Hydrophobicity ◽  
Future Research ◽  
And Performance ◽  
High Flexibility ◽  
Carbon Based Nanomaterials ◽  
Carbon Based

AbstractThis paper provides a comprehensive review of recent progress in the synthesis and performance of graphene and carbon-based nanomaterials as efficient adsorbents for oils and organic solvents. Several advantages of these adsorbents are emphasized, including adjustable three-dimensional networks, high surface area, high chemical/thermal stability, high flexibility and elasticity, and extremely high surface hydrophobicity/ oleophilicity. Technical challenges are discussed, and future research directions are proposed.

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