scholarly journals Effect of the Structural and Morphological Properties of Surfactant-Assisted Hydroxyapatite on Dermal Irritation and Antibacterial Activity

Materials ◽  
2021 ◽  
Vol 14 (21) ◽  
pp. 6522
Author(s):  
Giovanni García Domínguez ◽  
Sebastián Diaz De La Torre ◽  
Lorena Chávez Güitrón ◽  
Erasto Vergara Hernández ◽  
Joan Reyes Miranda ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Micrococcus Luteus ◽  
Hexagonal Phase ◽  
Sodium Dodecyl ◽  
Clinical Signs ◽  
Morphological Properties ◽  
X Ray Diffraction ◽  
Streptococcus Anginosus ◽  
Dermal Irritation ◽  
Cationic And Anionic Surfactants

Hydroxyapatite (HAp) nanoparticles with a homogeneous rod morphology were successfully synthesized using the hydrothermal method. The powders were characterized using Fourier transform infrared spectroscopy, X-ray diffraction, and scanning electron microscopy. The antibacterial and dermal irritation analyses of the samples were performed and discussed. The use of cationic and anionic surfactants, namely, cetyltrimethylammonium bromide (CTAB) and sodium dodecyl sulfate (SDS), respectively, at a low concentration (2.5 mol%) modified the length/diameter (L/D) ratio of the HAp rods. Structural characterizations of hydroxyapatite synthesized without surfactant (HA), with 2.5 and 5 mol% of SDS (SDS− and SDS+, respectively), and with 2.5 and 5 mol% of CTAB (CTAB− and CTAB+, respectively) revealed well-crystallized samples in the hexagonal phase. The CTAB− sample presented antibacterial activity against Pseudomonas aeruginosa, Escherichia coli, Streptococcus anginosus, Staphylococcus aureus, Micrococcus luteus, and Klebsiella pneumoniae, suggesting that antimicrobial susceptibility was promoted by the bacterial nature and the use of the surfactant. Dermal irritation showed no clinical signs of disease in rabbits during the study, where there was neither erythema nor necrosis at the inoculation sites.

scholarly journals Synthesis and Structural characterization of hydroxyapatite nanorods: Antibacterial activity and dermal irritation

2020 ◽  
Author(s):  
G. García Domínguez ◽  
Aristeo Garrido Hernández ◽  
S. Díaz de la Torre ◽  
L. Chávez Guitrón ◽  
M. Cruz Quezada ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Micrococcus Luteus ◽  
Hexagonal Phase ◽  
Sodium Dodecyl ◽  
Klebsiella Pneumonia ◽  
Streptococcus Anginosus ◽  
Dermal Irritation ◽  
Cationic And Anionic Surfactants ◽  
Structural Characterizations

Abstract Hydroxyapatite (HA) nanoparticles with homogeneous rod morphology were successfully synthesized by the hydrothermal method. The use of cationic and anionic surfactants (cetyltrimethylammonium bromide, CTAB, and sodium dodecyl sulfate, SDS) does not change the morphology, but the length/diameter ratio of HA nanorods did. The structural characterizations revealed well-crystallized samples in the hexagonal phase. The HA samples with a smaller Ca/P ratio presented larger crystalline size. The CTAB- sample present antibacterial activity against Pseudomonas aeruginosa, Escherichia coli, Streptococcus anginosus, Staphylococcus aureus, Micrococcus luteus, and Klebsiella pneumoniae suggesting that the bacteria nature and surface charge of nanoparticles affect the susceptibility.

Antibacterial Activity of Nickel -Doped ZnO\MWCNTs hybrid Prepared by Sol-Gel technique

2021 ◽  
Author(s):  
Selma M.H. AL-Jawad ◽  
Zahraa S. Shakir ◽  
Duha S. Ahmed
Keyword(s):  
Antibacterial Activity ◽  
Sol Gel ◽  
Inhibition Zone ◽  
Sem Analysis ◽  
Morphological Properties ◽  
X Ray Diffraction ◽  
Zno Nps ◽  
X Ray ◽  
Vis Spectroscopy ◽  
Doped Zno

ZnO/MWCNTs hybrid and doped with different concentration of Nickel element prepared by using Sol-gel been technique reported. All samples were prepared and characterized by X-Ray Diffraction Analysis (XRD), Energy Dispersive X-ray Spectroscopy (EDS), Fourier-Transform Infrared Spectroscopy (FTIR), Field-Emission Scanning Electron Microscopy (FE-SEM), and UV-Vis spectroscopy have been identified the structural, optical and morphological properties. X-ray diffraction showed the polycrystalline nature with hexagonal wutzite structure of hybrid and doped with Nickel. The crystalline size of the hybrid nanostructure was increasing from 23.73 nm to 34.59 nm. Besides, the UV-Vis spectroscopy showed a significant decrease in the band gap values from 2.97 eV to 2.01 eV. Whereas the FE-SEM analysis confirm the formation spherical shapes of ZnO NPs deposited on cylindrical tubes representing the MWCNTs. The antibacterial activity reveals that the inhibition zone of Ni doped-ZnO/MWCNTs hybrid was 28.5 mm, 26.5 mm toward E. coli and S. aureus bacteria, respectively.

scholarly journals Synthesis and Characterization of Conductive Polypyrrole: The Influence of the Oxidants and Monomer on the Electrical, Thermal, and Morphological Properties

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Abdirahman Yussuf ◽  
Mohammad Al-Saleh ◽  
Salah Al-Enezi ◽  
Gils Abraham
Keyword(s):  
Electrical Resistivity ◽  
Room Temperature ◽  
Oxidative Polymerization ◽  
Sodium Dodecyl ◽  
Conductive Polymer ◽  
Morphological Properties ◽  
X Ray Diffraction ◽  
Scanning Calorimetry ◽  
Structural Formation ◽  
Pyrrole Monomer

Conductive polymer, polypyrrole (PPy), was synthesized by chemical oxidative polymerization technique for a period of four hours at room temperature using pyrrole monomer (mPPy) in aqueous solution. Different oxidants such as ferric chloride (FeCl3) and ammonium persulphate (N2H8S2O8) and surfactant sodium dodecyl sulphate (C12H25NaO4S) were used. The produced PPy samples were characterized by using different techniques such as the electrical resistivity by four probe technique, thermogravimetry analysis (TGA), differential scanning calorimetry (DSC), Fourier transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD), and scanning electron microscopy (SEM). The performance of the oxidants has been investigated and compared. It was found that both oxidants, FeCl3 and N2H8S2O8, have decreased electrical resistivity as a function of temperature, which means increased conductivity. However, FeCl3 has achieved better performance than N2H8S2O8, where it has achieved a lower resistivity of about 60 ohms at room temperature, which indicates higher conductivity of PPy samples with FeCl3 as an oxidant. Similarly, further investigation of FeCl3 oxidant has been conducted by varying its concentration, and its influence on the final properties was reported. It has been observed that the morphology of PPy samples has a significant influence on the conductivity. It was found that 0.1 M and 0.05 M concentrations of FeCl3 oxidant and monomer, respectively, have achieved better thermal stability, which is FeCl3/mPPy ratio of 2 as an optimum value. FTIR and XRD results confirmed the structural formation of polypyrrole from pyrrole monomer during the synthesizing process.

Synthesis and Antibacterial Activity of Silver Nanoparticles Against Escherichia coli and Pseudomonas sp.

2021 ◽  
Author(s):  
Md. Irfanul Hoque ◽  
Sultana Afrin Jahan Rima ◽  
Md. Salah Uddin ◽  
M. Julkarnain
Keyword(s):  
Escherichia Coli ◽  
Silver Nanoparticles ◽  
Antibacterial Activity ◽  
Chemical Reduction ◽  
Bacterial Species ◽  
Sodium Dodecyl ◽  
Antibacterial Properties ◽  
Diffusion Method ◽  
Bacterial Strains ◽  
X Ray Diffraction

Silver nanoparticles (AgNPs) have been synthesized by chemical reduction method using ascorbic acid as reducing agent. Silver nitrate (AgNO[Formula: see text] and sodium dodecyl sulfate (SDS) have been used as precursor and stabilizer, respectively. The prepared samples were characterized by UV-visible spectroscopy, scanning electron microscopy (SEM) and X-ray diffraction (XRD). The antibacterial activity of prepared silver nanoparticles has been assessed by using the disc diffusion method against pathogenic, gram-negative bacterial strains including Escherichia coli and Pseudomonassp. To evaluate the potential antibacterial properties of AgNPs, the discs have been impregnated and dried with three different doses like 50, 100 and 150[Formula: see text][Formula: see text]l of 20[Formula: see text][Formula: see text]g/ml concentrated AgNPs solution and placed on the Petri-dishes. The antibiotic kanamycin (5[Formula: see text][Formula: see text]g) was used as control. In all the cases, a clear and distinct zone of inhibition is observed, which suggests that AgNPs can be used as effective growth inhibitors of various bacterial species and would be promising candidate for future development of antibacterial agents.

ANTIBIOTIC PROFILE AND ANTIBACTERIAL ACTIVITY OF COPPER OXIDE NANOPARTICLES AGAINST Pseudomonas fluorescens ISOLATED FROM WOUND INFECTION

2019 ◽  
Vol 9 (o3) ◽  
Author(s):  
Haider Qassim Raheem ◽  
Takwa S. Al-meamar ◽  
Anas M. Almamoori
Keyword(s):  
Antibacterial Activity ◽  
Copper Oxide ◽  
Pseudomonas Fluorescens ◽  
Wide Spectrum ◽  
Copper Oxide Nanoparticles ◽  
Morphological Properties ◽  
Clinical Samples ◽  
Oxide Nanoparticles ◽  
Cuo Nps ◽  
Disk Diffusion Assay

Fifty specimens were collected from wound patients who visited Al-Hilla Teaching Hospital. The samples were grown on Blood and MacConkey agar for 24-48 hr at 37oC. The bacterial isolates which achieved as a pure and predominant growth from clinical samples as Pseudomonas fluorescens, were identified using morphological properties and Vitek2 system. The anti-bacterial activity of copper oxide nanoparticles (CuO NPs) against was tested by (disk diffusion assay) using dilutions of (400, 200, 100, 50, 25, and 12.5‎µ‎g/ml). The (MIC and MBC) of each isolate was determined. CuO NPs shows wide spectrum antibacterial activity against tested bacteria with rise zone of inhibition diameter that is proportionate with the increase in nanoparticle concentration. The MIC of CuO NPs extended from 100-200‎µ‎g/ml and the MBC ranged from 200-400‎µ‎g/ml. The antibiotic profile was determined by Viteck 2 compact system (Biomérieux). CuO NPs‎ found highly effective and safe in P. fluorescens wounds infections comparing with used antibiotics.

Green synthesis, characterization of silver sulfide nanoparticles and antibacterial activity evaluation

2019 ◽  
Author(s):  
Chem Int
Keyword(s):  
Antibacterial Activity ◽  
Large Scale ◽  
Research Work ◽  
Silver Sulfide ◽  
Morphological Properties ◽  
Effective Diameter ◽  
Novel Approach ◽  
Transmission Electron ◽  
Green Route ◽  
Silver Sulfide Nanoparticles

This research work presents a facile and green route for synthesis silver sulfide (Ag2SNPs) nanoparticles from silver nitrate (AgNO3) and sodium sulfide nonahydrate (Na2S.9H2O) in the presence of rosemary leaves aqueous extract at ambient temperature (27 oC). Structural and morphological properties of Ag2SNPs nanoparticles were analyzed by X-ray diffraction (XRD) and transmission electron microscopy (TEM). The surface Plasmon resonance for Ag2SNPs was obtained around 355 nm. Ag2SNPs was spherical in shape with an effective diameter size of 14 nm. Our novel approach represents a promising and effective method to large scale synthesis of eco-friendly antibacterial activity silver sulfide nanoparticles.

Iso-octenidine: Promising Octenidine Analogue with Improved Solubility

2020 ◽  
Vol 17 ◽  
Author(s):  
Igor K. Yakuschenko ◽  
Nataliya N. Pozdeeva ◽  
Viktoriya A. Mumyatova ◽  
Alexey A. Terentiev ◽  
Svyatoslav Ya. Gadomsky
Keyword(s):  
Escherichia Coli ◽  
Antibacterial Activity ◽  
Micrococcus Luteus ◽  
Octenidine Dihydrochloride ◽  
First Time

: Iso-octenidine, an isomer of octenidine dihydrochloride, was synthesized and studied for the first time. Isooctenidine was demonstrated to be 3-fold more soluble in water in comparison to original octenidine, and both substances had remarkably similar antibacterial activity (tested on Escherichia Coli and Micrococcus luteus).

scholarly journals Photoluminescent Properties of Hydroxyapatite and Hydroxyapatite/Multi-Walled Carbon Nanotube Composites

Crystals ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 832
Author(s):  
Edna X. Figueroa-Rosales ◽  
Javier Martínez-Juárez ◽  
Esmeralda García-Díaz ◽  
Daniel Hernández-Cruz ◽  
Sergio A. Sabinas-Hernández ◽  
...  
Keyword(s):  
Carbon Nanotube ◽  
Hexagonal Phase ◽  
Precipitation Method ◽  
X Ray Diffraction ◽  
X Ray ◽  
Multi Walled Carbon Nanotube ◽  
Nanotube Composites ◽  
Carbon Nanotube Composites ◽  
Co Precipitation ◽  
Functionalized Mwcnts

Hydroxyapatite (HAp) and hydroxyapatite/multi-walled carbon nanotube (MWCNT) composites were obtained by the co-precipitation method, followed by ultrasound-assisted and microwave radiation and thermal treatment at 250 °C. X-ray diffraction (XRD) confirmed the presence of a hexagonal phase in all the samples, while Fourier-transform infrared (FTIR) spectroscopy elucidated the interaction between HAp and MWCNTs. The photoluminescent technique revealed that HAp and the composite with non-functionalized MWCNTs present a blue luminescence, while the composite with functionalized MWCNTs, under UV-vis radiation shows an intense white emission. These findings allowed presentation of a proposal for the use of HAp and HAp with functionalized MWCNTs as potential materials for optoelectronic and medical applications.

scholarly journals Utilization of induction furnace steel slag based iron oxide nanocomposites for antibacterial studies

2021 ◽  
Vol 3 (3) ◽  
Author(s):  
J. Baalamurugan ◽  
V. Ganesh Kumar ◽  
T. Stalin Dhas ◽  
S. Taran ◽  
S. Nalini ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Iron Oxide ◽  
Building Materials ◽  
Induction Furnace ◽  
Micrococcus Luteus ◽  
Bacterial Species ◽  
Steel Slag ◽  
If Steel ◽  
Growth Inhibitory ◽  
Microplate Reader

AbstractMetals and metal oxide-based nanocomposites play a significant role over the control of microbes. In this study, antibacterial activity of iron oxide (Fe2O3) nanocomposites based on induction furnace (IF) steel slag has been carried out. IF steel slag is an industrial by-product generated from secondary steel manufacturing process and has various metal oxides which includes Al2O3 (7.89%), MnO (5.06), CaO (1.49%) and specifically Fe2O3 (14.30%) in higher content along with metalloid SiO2 (66.42). Antibacterial activity of iron oxide nanocomposites has been revealed on bacterial species such as Micrococcus luteus, Bacillus subtilis and Staphylococcus aureus. Micrococcus luteus has undergone maximum zone of inhibition (ZOI) of 12 mm for 10 mg/mL concentration of steel slag iron oxide nanocomposite. Growth inhibitory kinetics of bacterial species has been studied using ELISA microplate reader at 660 nm by varying the concentration of steel slag iron oxide nanocomposites. The results illustrate that IF steel slag is a potential material and can be utilized in building materials to increase the resistance against biodeterioration. Graphic abstract

scholarly journals Tantalum doped SiO2-CaO-P2O5 based bioactive glasses: Investigation of in vitro bioactivity and antibacterial activities

2020 ◽  
Vol 6 (1) ◽  
pp. 10-22
Author(s):  
Zakaria Tabia ◽  
Sihame Akhtach ◽  
Khalil El Mabrouk ◽  
Meriame Bricha ◽  
Khalid Nouneh ◽  
...  
Keyword(s):  
Antibacterial Activities ◽  
Silica Matrix ◽  
Morphological Properties ◽  
Metallic Ions ◽  
X Ray Diffraction ◽  
Bioactive Glasses ◽  
E Coli ◽  
Fourier Transformed Infrared Spectroscopy ◽  
Electron Scanning Microscopy

AbstractMultifunctionality can be achieved for bioactive glasses by endowing them with multiple other properties along with bioactivity. One way to address this topic is by doping these glasses with therapeutic metallic ions. In this work, we put under investigation a series of bioactive glasses doped with tantalum. We aim to study the effect of tantalum, on the structure, bioactivity and antibacterial property of a ternary bioactive glass composition based on SiO2-CaO-P2O5. Fourier Transformed Infrared Spectroscopy (FTIR), X-Ray Diffraction (XRD) and Electron Scanning Microscopy (SEM) were used to assess the structural and morphological properties of these glasses and monitor their changes after in vitro acellular bioactivity test. Antibacterial activity was tested against gram positive and negative bacteria. Characterization results confirmed the presence of calcium carbonate crystallites along with the amorphous silica matrix. The assessment of bioactivity in SBF indicated that all compositions showed a fast bioactive response after only six hours of immersion period. However, analytical characterization revealed that tantalum introduced a slight latency in hydroxyapatite deposition at higher concentrations (0.8-1 %mol). Antibacterial test showed that tantalum ions had an inhibition effect on the growth of E. coli and S. aureus. This effect was more pronounced in compositions where mol% of tantalum is superior to 0.4%. These results proved that tantalum could be used, in intermediate proportions, as a promising multifunctional dopant element in bioactive glasses for bone regeneration applications.

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