scholarly journals Domain Heuristic Fusion of Multi-Word Embeddings for Nutrient Value Prediction

Mathematics ◽  
2021 ◽  
Vol 9 (16) ◽  
pp. 1941
Author(s):  
Gordana Ispirova ◽  
Tome Eftimov ◽  
Barbara Koroušić Seljak

Being both a poison and a cure for many lifestyle and non-communicable diseases, food is inscribing itself into the prime focus of precise medicine. The monitoring of few groups of nutrients is crucial for some patients, and methods for easing their calculations are emerging. Our proposed machine learning pipeline deals with nutrient prediction based on learned vector representations on short text–recipe names. In this study, we explored how the prediction results change when, instead of using the vector representations of the recipe description, we use the embeddings of the list of ingredients. The nutrient content of one food depends on its ingredients; therefore, the text of the ingredients contains more relevant information. We define a domain-specific heuristic for merging the embeddings of the ingredients, which combines the quantities of each ingredient in order to use them as features in machine learning models for nutrient prediction. The results from the experiments indicate that the prediction results improve when using the domain-specific heuristic. The prediction models for protein prediction were highly effective, with accuracies up to 97.98%. Implementing a domain-specific heuristic for combining multi-word embeddings yields better results than using conventional merging heuristics, with up to 60% more accuracy in some cases.

Mathematics ◽  
2020 ◽  
Vol 8 (10) ◽  
pp. 1811
Author(s):  
Gordana Ispirova ◽  
Tome Eftimov ◽  
Barbara Koroušić Seljak

Assessing nutritional content is very relevant for patients suffering from various diseases, professional athletes, and for health reasons is becoming part of everyday life for many. However, it is a very challenging task as it requires complete and reliable sources. We introduce a machine learning pipeline for predicting macronutrient values of foods using learned vector representations from short text descriptions of food products. On a dataset used from health specialists, containing short descriptions of foods and macronutrient values: we generate paragraph embeddings, introduce clustering in food groups, using graph-based vector representations, that include food domain knowledge information, and train regression models for each cluster. The predictions are for four macronutrients: carbohydrates, fat, protein and water. The highest accuracy was obtained for carbohydrate predictions – 86%, compared to the baseline – 27% and 36%. The protein predictions yielded the best results across all clusters, 53%–77% of the values fall in the tolerance-level range. These results were obtained using short descriptions, the embeddings can be improved if they are learned on longer descriptions, which would lead to better prediction results. Since the task of calculating macronutrients requires exact quantities of ingredients, these results obtained only from short description are a huge leap forward.


Symmetry ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 89 ◽  
Author(s):  
Hsiang-Yuan Yeh ◽  
Yu-Ching Yeh ◽  
Da-Bai Shen

Linking textual information in finance reports to the stock return volatility provides a perspective on exploring useful insights for risk management. We introduce different kinds of word vector representations in the modeling of textual information: bag-of-words, pre-trained word embeddings, and domain-specific word embeddings. We apply linear and non-linear methods to establish a text regression model for volatility prediction. A large number of collected annually-published financial reports in the period from 1996 to 2013 is used in the experiments. We demonstrate that the domain-specific word vector learned from data not only captures lexical semantics, but also has better performance than the pre-trained word embeddings and traditional bag-of-words model. Our approach significantly outperforms with smaller prediction error in the regression task and obtains a 4%–10% improvement in the ranking task compared to state-of-the-art methods. These improvements suggest that the textual information may provide measurable effects on long-term volatility forecasting. In addition, we also find that the variations and regulatory changes in reports make older reports less relevant for volatility prediction. Our approach opens a new method of research into information economics and can be applied to a wide range of financial-related applications.


2019 ◽  
Vol 10 (1) ◽  
pp. 24-33 ◽  
Author(s):  
Christian Tronstad ◽  
Runar Strand-Amundsen

Abstract The relation between a biological process and the changes in passive electrical properties of the tissue is often non-linear, in which developing prediction models based on bioimpedance spectra is not trivial. Relevant information on tissue status may also lie in characteristic developments in the bioimpedance spectra over time, often neglected by conventional methods. The aim of this study was to explore possibilities in machine learning methods for time series of bioimpedance spectra, where we used organ ischemia as an example. Based on published data on the development of the bioimpedance spectrum during liver ischemia, a simulation model was made and used to generate sets of synthetic data with different levels of organ-to-organ variation, measurement noise and drift. Three types of artificial neural networks were employed in learning to predict the ischemic duration, based on the simulated datasets. The simulated prediction performance was very dependent on the amount of training examples, the organ-to-organ variation and the selection of input variables from the bioimpedance spectrum. The performance was also affected by noise and drift in the measurement, but a recurrent neural network with long short-term memory units could obtain good predictions even on noisy and drifting measurements. This approach may be relevant for further exploration on several applications of bioimpedance having the purpose of predicting a biological state based on spectra measured over time.


Author(s):  
Marko Robnik-Šikonja ◽  
Kristjan Reba ◽  
Igor Mozetič

Word embeddings represent words in a numeric space so that semantic relations between words are represented as distances and directions in the vector space. Cross-lingual word embeddings transform vector spaces of different languages so that similar words are aligned. This is done by mapping one language’s vector space to the vector space of another language or by construction of a joint vector space for multiple languages. Cross-lingual embeddings can be used to transfer machine learning models between languages, thereby compensating for insufficient data in less-resourced languages. We use cross-lingual word embeddings to transfer machine learning prediction models for Twitter sentiment between 13 languages. We focus on two transfer mechanisms that recently show superior transfer performance. The first mechanism uses the trained models whose input is the joint numerical space for many languages as implemented in the LASER library. The second mechanism uses large pretrained multilingual BERT language models. Our experiments show that the transfer of models between similar languages is sensible, even with no target language data. The performance of cross-lingual models obtained with the multilingual BERT and LASER library is comparable, and the differences are language-dependent. The transfer with CroSloEngual BERT, pretrained on only three languages, is superior on these and some closely related languages.


2021 ◽  
Author(s):  
Ridam Pal ◽  
Harshita Chopra ◽  
Raghav Awasthi ◽  
Harsh Bandhey ◽  
Aditya Nagori ◽  
...  

BACKGROUND Evidence from peer-reviewed literature is the cornerstone for designing responses to global threats such as COVID-19. The collection of knowledge in publications needs to be distilled into evidence by leveraging natural language models and machine learning. OBJECTIVE We aim to show that new knowledge can be captured and tracked using the temporal change in the underlying unsupervised word embeddings of literature. Further imminent themes can be predicted using machine learning upon the evolving associations between words. METHODS Frequently occurring medical entities were extracted from the abstracts of more than 150,000 COVID-19 articles published on the WHO database, collected on a monthly interval starting from February 2020. Word embeddings trained on each month's literature were used to construct networks of entities with cosine similarities as edge weights. Topological features of the subsequent month’s network were forecasted based on prior patterns and new links were predicted using supervised machine learning. Community detection and alluvial diagrams were used to track biomedical themes that evolved over the months. RESULTS We found that thromboembolic complications were detected as an emerging theme as early as August 2020. A shift towards symptoms of Long COVID complications was observed during March 2021 and neurological complications gained significance in June 2021. A prospective validation of the link prediction models achieved an AUROC score of 0.87. Predictive modelling revealed predisposing conditions, symptoms, cross-infection and neurological complications as a dominant research theme in COVID-19 publications based on patterns observed in previous months. CONCLUSIONS Machine learning-based prediction of emerging links can contribute towards steering research by capturing themes represented by groups of medical entities, based on patterns of semantic relationships over time.


2017 ◽  
Author(s):  
Sabrina Jaeger ◽  
Simone Fulle ◽  
Samo Turk

Inspired by natural language processing techniques we here introduce Mol2vec which is an unsupervised machine learning approach to learn vector representations of molecular substructures. Similarly, to the Word2vec models where vectors of closely related words are in close proximity in the vector space, Mol2vec learns vector representations of molecular substructures that are pointing in similar directions for chemically related substructures. Compounds can finally be encoded as vectors by summing up vectors of the individual substructures and, for instance, feed into supervised machine learning approaches to predict compound properties. The underlying substructure vector embeddings are obtained by training an unsupervised machine learning approach on a so-called corpus of compounds that consists of all available chemical matter. The resulting Mol2vec model is pre-trained once, yields dense vector representations and overcomes drawbacks of common compound feature representations such as sparseness and bit collisions. The prediction capabilities are demonstrated on several compound property and bioactivity data sets and compared with results obtained for Morgan fingerprints as reference compound representation. Mol2vec can be easily combined with ProtVec, which employs the same Word2vec concept on protein sequences, resulting in a proteochemometric approach that is alignment independent and can be thus also easily used for proteins with low sequence similarities.


2019 ◽  
Author(s):  
Oskar Flygare ◽  
Jesper Enander ◽  
Erik Andersson ◽  
Brjánn Ljótsson ◽  
Volen Z Ivanov ◽  
...  

**Background:** Previous attempts to identify predictors of treatment outcomes in body dysmorphic disorder (BDD) have yielded inconsistent findings. One way to increase precision and clinical utility could be to use machine learning methods, which can incorporate multiple non-linear associations in prediction models. **Methods:** This study used a random forests machine learning approach to test if it is possible to reliably predict remission from BDD in a sample of 88 individuals that had received internet-delivered cognitive behavioral therapy for BDD. The random forest models were compared to traditional logistic regression analyses. **Results:** Random forests correctly identified 78% of participants as remitters or non-remitters at post-treatment. The accuracy of prediction was lower in subsequent follow-ups (68%, 66% and 61% correctly classified at 3-, 12- and 24-month follow-ups, respectively). Depressive symptoms, treatment credibility, working alliance, and initial severity of BDD were among the most important predictors at the beginning of treatment. By contrast, the logistic regression models did not identify consistent and strong predictors of remission from BDD. **Conclusions:** The results provide initial support for the clinical utility of machine learning approaches in the prediction of outcomes of patients with BDD. **Trial registration:** ClinicalTrials.gov ID: NCT02010619.


2020 ◽  
Author(s):  
Sina Faizollahzadeh Ardabili ◽  
Amir Mosavi ◽  
Pedram Ghamisi ◽  
Filip Ferdinand ◽  
Annamaria R. Varkonyi-Koczy ◽  
...  

Several outbreak prediction models for COVID-19 are being used by officials around the world to make informed-decisions and enforce relevant control measures. Among the standard models for COVID-19 global pandemic prediction, simple epidemiological and statistical models have received more attention by authorities, and they are popular in the media. Due to a high level of uncertainty and lack of essential data, standard models have shown low accuracy for long-term prediction. Although the literature includes several attempts to address this issue, the essential generalization and robustness abilities of existing models needs to be improved. This paper presents a comparative analysis of machine learning and soft computing models to predict the COVID-19 outbreak as an alternative to SIR and SEIR models. Among a wide range of machine learning models investigated, two models showed promising results (i.e., multi-layered perceptron, MLP, and adaptive network-based fuzzy inference system, ANFIS). Based on the results reported here, and due to the highly complex nature of the COVID-19 outbreak and variation in its behavior from nation-to-nation, this study suggests machine learning as an effective tool to model the outbreak. This paper provides an initial benchmarking to demonstrate the potential of machine learning for future research. Paper further suggests that real novelty in outbreak prediction can be realized through integrating machine learning and SEIR models.


2019 ◽  
Vol 21 (9) ◽  
pp. 662-669 ◽  
Author(s):  
Junnan Zhao ◽  
Lu Zhu ◽  
Weineng Zhou ◽  
Lingfeng Yin ◽  
Yuchen Wang ◽  
...  

Background: Thrombin is the central protease of the vertebrate blood coagulation cascade, which is closely related to cardiovascular diseases. The inhibitory constant Ki is the most significant property of thrombin inhibitors. Method: This study was carried out to predict Ki values of thrombin inhibitors based on a large data set by using machine learning methods. Taking advantage of finding non-intuitive regularities on high-dimensional datasets, machine learning can be used to build effective predictive models. A total of 6554 descriptors for each compound were collected and an efficient descriptor selection method was chosen to find the appropriate descriptors. Four different methods including multiple linear regression (MLR), K Nearest Neighbors (KNN), Gradient Boosting Regression Tree (GBRT) and Support Vector Machine (SVM) were implemented to build prediction models with these selected descriptors. Results: The SVM model was the best one among these methods with R2=0.84, MSE=0.55 for the training set and R2=0.83, MSE=0.56 for the test set. Several validation methods such as yrandomization test and applicability domain evaluation, were adopted to assess the robustness and generalization ability of the model. The final model shows excellent stability and predictive ability and can be employed for rapid estimation of the inhibitory constant, which is full of help for designing novel thrombin inhibitors.


2020 ◽  
Vol 16 ◽  
Author(s):  
Nitigya Sambyal ◽  
Poonam Saini ◽  
Rupali Syal

Background and Introduction: Diabetes mellitus is a metabolic disorder that has emerged as a serious public health issue worldwide. According to the World Health Organization (WHO), without interventions, the number of diabetic incidences is expected to be at least 629 million by 2045. Uncontrolled diabetes gradually leads to progressive damage to eyes, heart, kidneys, blood vessels and nerves. Method: The paper presents a critical review of existing statistical and Artificial Intelligence (AI) based machine learning techniques with respect to DM complications namely retinopathy, neuropathy and nephropathy. The statistical and machine learning analytic techniques are used to structure the subsequent content review. Result: It has been inferred that statistical analysis can help only in inferential and descriptive analysis whereas, AI based machine learning models can even provide actionable prediction models for faster and accurate diagnose of complications associated with DM. Conclusion: The integration of AI based analytics techniques like machine learning and deep learning in clinical medicine will result in improved disease management through faster disease detection and cost reduction for disease treatment.


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