scholarly journals Intrapartum Analgesia—Have Women’s Preferences Changed over the Last Decade?

Medicina ◽  
2022 ◽  
Vol 58 (1) ◽  
pp. 87
Author(s):  
Agnieszka Jodzis ◽  
Maciej Walędziak ◽  
Krzysztof Czajkowski ◽  
Anna Różańska-Walędziak
Keyword(s):  
Social Media ◽  
Pain Relief ◽  
Alternative Methods ◽  
Time Points ◽  
The Past ◽  
Global Access ◽  
Women’S Preferences ◽  
Women's Knowledge ◽  
To Receive ◽  
Women’S Knowledge

Background: Global access to social media has supposedly changed women’s awareness about the pharmacological and alternative methods of pain relief during vaginal delivery. The purpose of the study was to analyze changes in women’s preference and opinion about different forms of labor analgesia over the past decade. Materials and methods: The study was designed as an anonymous survey with questions about women’s knowledge and preference of different forms of pain relief in labor. The survey was conducted in 2010 and 2020, with data collected from 1175 women in 2010 and 1033 in 2020. Results: There were no differences between 2010 and 2020 in the proportion of women who wanted to receive analgesia in labor, at, respectively 67.9% of women in 2010 and 73.9% in 2020. About 50% of women chose epidural analgesia as the only efficacious method of pain relief in labor both in 2010 and 2020. There were no differences between the two time-points in the distribution of chosen methods of pain relief. In total, 92.3% of women in 2010 and 94.9% in 2020 thought that they should have the possibility of independent choice of analgesia method before the delivery (p < 0.04). Conclusions: A high proportion of Polish women choose EDA over other pharmacological and nonpharmacological methods of pain relief in labor, and this preference has not changed over the last decade. Increasing women’s knowledge about different methods of intrapartum pain relief may lead to wider use of nonpharmacological methods of pain relief.

The Friday Effect: Firm Lobbying, the Timing of Drug Safety Alerts, and Drug Side Effects

2020 ◽  
Vol 66 (8) ◽  
pp. 3677-3698
Author(s):  
Luis Diestre ◽  
Benjamin Barber ◽  
Juan Santaló
Keyword(s):  
Social Media ◽  
Side Effects ◽  
News Coverage ◽  
Healthcare Management ◽  
Drug Side Effects ◽  
The Past ◽  
Safety Alert ◽  
Day Of The Week ◽  
To Receive ◽  
The U.S

Safety alerts are announcements made by health regulators warning patients and doctors about new drug-related side effects. However, not all safety alerts are equally effective. We provide evidence that the day of the week on which the safety alerts are announced explains differences in safety alert impact. Specifically, we show that safety alerts announced on Fridays are less broadly diffused: they are shared 34% less on social media, mentioned in 23% to 66% fewer news articles, and are 12% to 51% less likely to receive any news coverage at all. As a consequence of this, we propose Friday alerts are less effective in reducing drug-related side effects. We find that moving a Friday alert to any other weekday would reduce all drug-related side effects by 9% to 12%, serious drug-related complications by 6% to 15%, and drug-related deaths by 22% to 36%. This problem is particularly important because Friday was the most frequent weekday for safety alert announcements from 1999 to 2016. We show that this greater prevalence of Friday alerts might not be random: firms that lobbied the U.S. Food and Drug Administration in the past are 49% to 56% more likely to have safety alerts announced on Fridays. This paper was accepted by Stefan Scholtes, healthcare management.

Provision of Remedies for Violation of Economic, Social and Cultural Rights: A Comparative Study of the United Nations, Inter-American and African Human Rights Systems

2020 ◽  
Vol 28 (2) ◽  
pp. 298-318
Author(s):  
Roman Girma Teshome
Keyword(s):  
Human Rights ◽  
United Nations ◽  
Comparative Study ◽  
Economic Rights ◽  
Regional Monitoring ◽  
Cultural Rights ◽  
The Past ◽  
The United Nations ◽  
To Receive

The effectiveness of human rights adjudicative procedures partly, if not most importantly, hinges upon the adequacy of the remedies they grant and the implementation of those remedies. This assertion also holds water with regard to the international and regional monitoring bodies established to receive individual complaints related to economic, social and cultural rights (hereinafter ‘ESC rights’ or ‘socio-economic rights’). Remedies can serve two major functions: they are meant, first, to rectify the pecuniary and non-pecuniary damage sustained by the particular victim, and second, to resolve systematic problems existing in the state machinery in order to ensure the non-repetition of the act. Hence, the role of remedies is not confined to correcting the past but also shaping the future by providing reforming measures a state has to undertake. The adequacy of remedies awarded by international and regional human rights bodies is also assessed based on these two benchmarks. The present article examines these issues in relation to individual complaint procedures that deal with the violation of ESC rights, with particular reference to the case laws of the three jurisdictions selected for this work, i.e. the United Nations, Inter-American and African Human Rights Systems.

Investigating Applicability of the Meshfree Method to the Structural Analysis of Tires

2012 ◽  
Vol 40 (2) ◽  
pp. 60-82
Author(s):  
Ken Ishihara ◽  
Takehiro Noda ◽  
Hiroyuki Sakurai
Keyword(s):  
Meshfree Method ◽  
Alternative Methods ◽  
The Finite Element Method ◽  
Tire Industry ◽  
Academic Communities ◽  
The Past ◽  
New Methodologies ◽  
Tire Modeling ◽  
Point Data ◽  
Conducting Research

ABSTRACT In contrast to the finite element method (FEM), which is widely used in the tire industry nowadays, some alternative methods have been proposed by academic communities over the past decade or so. The meshfree method is one of those new methodologies. Originally intended to remove the burden of creating the mesh that is inherent in FEM, the meshfree method relies on the point data rather than the mesh, which makes it much easier to discretize the geometry. In addition to those modeling issues, it has been found that the meshfree method has several advantages over FEM in handling geometrical nonlinearities, continuities, and so forth. In accordance with those emerging possibilities, the authors have been conducting research on the matter. This article describes the results of the authors' preliminary research on the applicability of the meshfree method to tire analyses, which include the theoretical outline, the strategy of tire modeling, numerical results, comparisons with results of FEM, and conclusions.

PENERAPAN NILAI-NILAI MORAL PADA SANTRI TPQ AL-KHUMAIER PEKANBARU

Generasi Emas ◽  
2018 ◽  
Vol 1 (1) ◽  
pp. 51
Author(s):  
Ida Windi Wahyuni
Keyword(s):  
Social Media ◽  
Moral Education ◽  
Internal Control ◽  
Growth And Development ◽  
Moral Values ◽  
Early Age ◽  
Global Era ◽  
Good And Evil ◽  
To Receive ◽  
Control Tool

Moral planting to children from an early age is very important considering that in the era of an increasingly global era, moral education as the basis of self-discipline to be an internal control tool in behaving consistently in religion. A child is naturally created in a state ready to receive good and evil. The habituation of religious and moral values ​​for early childhood is very important to apply as early as possible to the most basic foundation in the process of growth and development of children. The objectives of this research are (1) To describe TPQ Al-Khumaier program, (2) To describe the application of moral values ​​to students by TPQ Al-Khumaier teacher (3) To know the obstacles in applying moral values ​​to the students of TPQ Al-Khumaier and looking for a solution. The results of this study indicate that the program TPQ Al-Khumaier has been implemented according to the program prepared by the school in collaboration with Kemenag Pekanbaru. The application of santri moral values ​​has been practiced in the activities and the process of habituation and modeling of the teachers. The obstacles are the duration of the meeting, social outside TPQ, including social media at home and in the neighborhood where students live.

Temporal disconnection between pain relief and trigeminal nerve microstructural changes after Gamma Knife radiosurgery for trigeminal neuralgia

2020 ◽  
Vol 133 (3) ◽  
pp. 727-735
Author(s):  
Peter Shih-Ping Hung ◽  
Sarasa Tohyama ◽  
Jia Y. Zhang ◽  
Mojgan Hodaie
Keyword(s):  
Pain Relief ◽  
Trigeminal Neuralgia ◽  
Pain Intensity ◽  
Gamma Knife ◽  
Trigeminal Nerve ◽  
Diffusion Tensor ◽  
Gamma Knife Radiosurgery ◽  
Time Points ◽  
Microstructural Effect

OBJECTIVEGamma Knife radiosurgery (GKRS) is a noninvasive surgical treatment option for patients with medically refractive classic trigeminal neuralgia (TN). The long-term microstructural consequences of radiosurgery and their association with pain relief remain unclear. To better understand this topic, the authors used diffusion tensor imaging (DTI) to characterize the effects of GKRS on trigeminal nerve microstructure over multiple posttreatment time points.METHODSNinety-two sets of 3-T anatomical and diffusion-weighted MR images from 55 patients with TN treated by GKRS were divided within 6-, 12-, and 24-month posttreatment time points into responder and nonresponder subgroups (≥ 75% and < 75% reduction in posttreatment pain intensity, respectively). Within each subgroup, posttreatment pain intensity was then assessed against pretreatment levels and followed by DTI metric analyses, contrasting treated and contralateral control nerves to identify specific biomarkers of successful pain relief.RESULTSGKRS resulted in successful pain relief that was accompanied by asynchronous reductions in fractional anisotropy (FA), which maximized 24 months after treatment. While GKRS responders demonstrated significantly reduced FA within the radiosurgery target 12 and 24 months posttreatment (p < 0.05 and p < 0.01, respectively), nonresponders had statistically indistinguishable DTI metrics between nerve types at each time point.CONCLUSIONSUltimately, this study serves as the first step toward an improved understanding of the long-term microstructural effect of radiosurgery on TN. Given that FA reductions remained specific to responders and were absent in nonresponders up to 24 months posttreatment, FA changes have the potential of serving as temporally consistent biomarkers of optimal pain relief following radiosurgical treatment for classic TN.

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