Characteristics of Periodontal Tissues in Prosthetic Treatment with Fixed Dental Prostheses

The objective of the present study was to investigate the effects of various types of fixed prostheses on periodontal tissues and explore the association of gingival biotype and gum recession in relation to prosthesis types. The study participants (N = 95) were divided into three groups based on the type of dental prosthesis: Group-I: cobalt-chrome (Co-Cr) ceramic prosthesis fabricated by the conventional method (n = 35); Group-II: consisted of patients with Co-Cr ceramic prostheses fabricated by a computer-aided design and computer aided manufacturing (CAD/CAM) technique (n = 30); and Group-III: zirconia-based prostheses fabricated by the CAD/CAM technique (n = 30). Following the use of prostheses, periodontal examinations were performed using the Community Periodontal Index (CPI) and Modified Approximal Plaque Index (MAPI). In addition, the gingival biotype was examined using a probe transparency method. The Statistical Package for the Social Sciences (SPSS), Version 20 (IBM Company, Chicago, IL, USA), was used to analyze the results, and the significance level was set at p = 0.05. It showed the MAPI results after the use of prosthetic rehabilitation for 12 months of periodontitis in 87.9% ± 15.4 of patients in Group-I, in 80.6% ± 17.97 in those in Group-II, and in 62.5% ± 21.4 in those in Group-III (p < 0.01). The CPI index results indicated a high prevalence of periodontal disease in all groups. The number of people with healthy periodontium constituted 17.1% of patients in Group-I, 24.2% in Group-II, and 37.1% in Group-III. Our study concluded that prosthetic treatment with periodontal diseases showed better outcomes while using dental prostheses fabricated by the CAD/CAM technique compared to the conventionally fabricated dental prostheses. The thin gingival biotype is more often associated with gingival recession than the thick biotype.

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MICROBIOLOGICAL ASSESSMENT OF CAD/CAM FABRICATED DENTURES & ITS CORRELATION WITH SURFACE PROPERTIES: A RANDOMIZED CLINICAL TRIAL

International Journal of Advanced Research ◽

10.21474/ijar01/13767 ◽

2021 ◽

Vol 9 (11) ◽

pp. 486-497

Author(s):

Mohamed A. Abuheikal ◽

◽

Sherihan M. Eissa ◽

Hisham S. El Gabry ◽

◽

...

Keyword(s):

Surface Roughness ◽

Surface Properties ◽

Complete Dentures ◽

Group Iii ◽

Group I ◽

Significant Difference ◽

Computer Aided ◽

Cad Cam ◽

3D Printed ◽

Group Ii

Background: Computer-aided design and computer-aided manufacturing (CAD-CAM) techniques have lately become a popular treatment option for complete dentures fabrication. The two principal CAD-CAM techniques milling and 3D printing used in complete dentures construction have been approved and documented in showing clinically good results. Surface characteristics of dentures fabricated by these new techniques have a great effect on microbiological adherence to denture fitting surfaces. Aim: As other clinical trials and/or in-vitro studies evaluating the microbiological effect and its correlation with the surface roughness of the two advanced manufacturing techniques and comparing it with the conventional technique are lacking. Thus, this study aimed to further assess the microbiological and surface properties of different widely used denture base materials. Methodology: Thirty-six completely edentulous patients were selected and divided randomly into three groups Group I patients received conventional complete denture, Group II patients received CAD/CAM milled complete dentures and Group III patients received 3D printed complete dentures. All denture`s surface roughness were evaluated, also all patients were recalled after 3, 9 & 12 months respectively to evaluate the microbiological adherence. Results: Microbiological count significantly increased (P < 0.05) after 12 months in all groups, after 12 months there was a significant difference (P < 0.05) between three groups as group II (Milled) was significantly the lowest, then the group I (conventional), while group III (3D printed) was significantly the highest. Regarding surface roughness of group II (milled) was significantly the lowest, while group III (3D printed) was significantly the highest. Finally, there was a strong positive significant correlation between microbiological adherence and surface roughness in all groups as (r > 0.5). Conclusion: Group II (Milled) appeared to be the best regarding microbiological adherence and surface roughness followed by the group I (conventional) and finally group III (3D printed). Furthermore, it was evident that surface roughness has a great effect on microbiological adherence regardless of the fabrication technique utilized.

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Comparison of dental caries and periodontal disease with dermatoglyphic patterns and salivary p

IP International Journal of Forensic Medicine and Toxicological Sciences ◽

10.18231/j.ijfmts.2021.022 ◽

2021 ◽

Vol 6 (3) ◽

pp. 102-107

Author(s):

D. Aruna ◽

T. Prasanth

Keyword(s):

Dental Caries ◽

Periodontal Disease ◽

Periodontal Diseases ◽

Genetic Disorders ◽

Descriptive Analysis ◽

Group Iii ◽

Group I ◽

Ulnar Loop ◽

Periodontal Index ◽

Group Ii

Dermatoglyphic patterns are dermal ridge configurations present on the fingers, palm, toes and soles of human which are valuable in the diagnosis of many diseases associated with genetic disorders. Although the aetiology of dental caries and periodontal diseases is multi-factorial, we hypothesize that they may have genetic predisposition. We also evaluated its association with environmental factors like salivary pto assess any possible correlation. This study aims to Compare Dental caries (DC) and chronic generalized periodontitis (CGP) with Dermatoglyphic patterns and salivary p. One hundred patients were divided into group I (40 DC patients), group II (40 CGP patients) and group III includes 20 healthy controls. DMFT (decayed missing filled teeth) index (> 5) from group I, Russell’s periodontal index (2-5) from group II patients were taken. Finger print patterns by ink method and salivary p by p strips were recorded from all the groups and analysed with descriptive analysis. Group I showed more incidence of whorl patterns at lower salivary p than Group II and III which was statistically significant (p<0.05). Group II showed more incidence of ulnar loop patterns at slightly lower p than Group I & III which was statistically significant (p<0.05).The present study showed DC seen in people with more number of whorl patterns and periodontal disease with more ulnar loop patterns at lower salivary P. Larger scale studies are warranted to confirm our findings before applying dermatoglyphics to predict an individual prone to develop DC and periodontal disease in clinical practice.

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Efficacy of hyaluronic acid in the treatment of chronic gingivitis in children

Vojnosanitetski pregled ◽

10.2298/vsp1112021i ◽

2011 ◽

Vol 68 (12) ◽

pp. 1021-1025

Author(s):

Marija Igic ◽

Dragan Mihailovic ◽

Ljiljana Kesic ◽

Mirjana Apostolovic ◽

Ljiljana Kostadinovic ◽

...

Keyword(s):

Hyaluronic Acid ◽

Control Group ◽

Treatment Needs ◽

Group Iii ◽

Group I ◽

Periodontal Index ◽

Before And After ◽

Community Periodontal Index ◽

Group Ii ◽

Basic Treatment

Introduction/Aim. Gingivitis is a common occurrence in children and may well be thought as a risk factor for the appearance and progression of the diseases of parodontal tissues. It is thus necessary to react in a timely and adequate fashion to prevent the disease to become serious and produce parodontopathy. The aim of the study was to establish the efficacy of hyaluronic acid in the treatment of chronic gingivitis in children. Methods. The study enrolled 130 children with permanent dentition. All of the examinees were divided into three groups: group I - 50 patients with chronic gingivitis in which only the basic treatment was applied; group II - 50 patients with chronic gingivitis in which hyaluronic acid was applied in addition to basic treatment; group III - 30 examinees with healthy gingiva (control group). Assessment of oral hygiene and status of the gingiva and parodontium was done using the appropriate indexes before and after the treatment. Inflammation of the gingiva was monitored by way of cytomorphometric studies. Results. The pretreatment values of the plaque index (PI) were high: in the group I PI was 1.94; in the group II PI was 1.68. After the treatment, the PI value was reduced to null in both groups (PI = 0). In the group III PI was 0.17. The bleeding index (BI) in the group I was 2.02 before and 0.32 after the treatment; the BI value in the group II was 1.74 before and 0.16 after the treatment. In the group III BI was 0. In the group I, the Community Periodontal Index of Treatment Needs (CPITN) was 1.66 before and 0.32 after the treatment; in the group II, the CPITN value was 1.5 before and 0.24 after the treatment. In the group III, the CPITN value was 0. In the group I, the size of the nuclei of the stratified squamous epithelium of the gingiva was reduced, although not so much as the nuclear size in the group II of examinees. Conclusion. Basic treatment is able to successfully treat chronic gingivitis in children. The use of hyaluronic acid together with the basic treatment can markedly improve the treatment effect.

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Effect of microwave treatments on dimensional accuracy of maxillary acrylic resin denture base

Brazilian Dental Journal ◽

10.1590/s0103-64402005000200006 ◽

2005 ◽

Vol 16 (2) ◽

pp. 119-123 ◽

Cited By ~ 22

Author(s):

Sabrina Pavan ◽

João Neudenir Arioli Filho ◽

Paulo Henrique dos Santos ◽

Francisco de Assis Mollo Jr.

Keyword(s):

Dimensional Accuracy ◽

Acrylic Resin ◽

Microwave Treatment ◽

Control Group ◽

Denture Base ◽

Group Iii ◽

Dental Prostheses ◽

Group I ◽

Group Ii ◽

Cycle Group

Microwave energy has been used as an alternative method for disinfection and sterilization of dental prostheses. This study evaluated the influence of microwave treatment on dimensional accuracy along the posterior palatal border of maxillary acrylic resin denture bases processed by water-bath curing. Thirty maxillary acrylic bases (3-mm-thick) were made on cast models with Clássico acrylic resin using routine technique. After polymerization and cooling, the sets were deflasked and the bases were stored in water for 30 days. Thereafter, the specimens were assigned to 3 groups (n=10), as follows: group I (control) was not submitted to any disinfection cycle; group II was submitted to microwave disinfection for 3 min at 500 W; and in group III microwaving was done for 10 min at 604 W. The acrylic bases were fixed on their respective casts with instant adhesive (Super Bonder®) and the base/cast sets were sectioned transversally in the posterior palatal zone. The existence of gaps between the casts and acrylic bases was assessed using a profile projector at 5 points. No statistically significant differences were observed between the control group and group II. However, group III differed statistically from the others (p<0.05). Treatment in microwave oven at 604 W for 10 min produced the greatest discrepancies in the adaptation of maxillary acrylic resin denture bases to the stone casts.

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COMPARATIVE EVALUATION OF THE BENEFITS OF ADJUNCTIVE USE OF LYCOPENE AND VITAMIN E IN NON-SURGICAL TREATMENT OF PERIODONTITIS : A RANDOMISED CLINICALAND MICROBIOLOGICAL STUDY

10.36106/ijsr/0517413 ◽

2020 ◽

pp. 3-5

Author(s):

Shrutika B. Borade ◽

Akshaya Banodkar ◽

Rajesh Gaikwad

Keyword(s):

Surgical Treatment ◽

Vitamin E ◽

Test Score ◽

Periodontal Diseases ◽

Group Iii ◽

Group I ◽

Group Ii ◽

Periodontal Healing ◽

Non Surgical Treatment ◽

Bana Test

Background-This study was aimed to compare and evaluate the benefits of adjunctive use of lycopene and vitamin E in the non-surgical treatment of periodontal diseases and effect of this treatment on the periodontal microflora. Methodology-Systemically healthy 30 chronic periodontitis patients were included in the study. periodontal examination was performed and BANA test score were obtained. patients were randomly divided into group-I, group-II and group-III. scaling and root planing was performed for all three groups. group-II and group-III were supplimented with lycopene (Lycostar) and Vit E(Evion 400mg)respectively for 1 month. PI, BOP, PPD, CAL and BANA test score were re-evaluated after 1 month. Result-Periodontal parameters and BANA test score were significantly reduced in both group-II and group-III as compared to group-I. Conclusion-Systemic administration of antioxidants improved periodontal healing and significantly reduced microbial load and can be used as an adjunct to non-surgical periodontal therapy.

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Clinical Aspects of Combination of Aesthetic Fixed Prosthetic Appliances

Galician Medical Journal ◽

10.21802/gmj.2017.3.10 ◽

2017 ◽

Vol 24 (3) ◽

Author(s):

Andrii Biben ◽

Zinovii Ozhohan

Keyword(s):

Surface Area ◽

Contact Surface ◽

Occlusal Surface ◽

Clinical Aspects ◽

Group Iii ◽

Contact Surface Area ◽

Dental Prostheses ◽

Group I ◽

Occlusal Surfaces ◽

Group Ii

The objective of the research was to study the peculiarities of the combination of zirconia and ceramic occlusal surfaces when constructing aesthetic fixed prosthetic appliances.Materials and methods. The study included 70 patients with zirconia and ceramic occlusal surfaces of aesthetic fixed dental prostheses. Group I included 24 patients with a combination of zirconia and ceramic occlusal surfaces. Group II included 30 patients with a combination of ceramic occlusal surfaces. Group III included 16 patients with a combination of zirconia occlusal surfaces. All the patients were observed 12 and 24 months after prosthetic repair.Results. 12 and 24 months after prosthetic repair, the occlusal contact surface area was the largest in Group II (8.18±0.16 mm2 and 9.17±0.1 mm2, respectively). In Group I, where only one occlusive surface was made of zirconium dioxide, significantly reduced levels of abrasion were observed as compared to Group II – 8.07±0.21 mm2 and 8.65±0.23 mm2, respectively. 36 months after denture wearing, in Group III, the smallest contact surface area – 7.84±0.15 mm2as well as the lowest growth of the surface area was observed – 8.07±0.13 mm2.Conclusions. Dental prostheses with at least one ceramic occlusal surface exhibit a strong tendency to abrasion and, consequently, to an increase in the occlusal surface area resulting in an excessive load on prosthetic appliance. Moreover, functional and aesthetic values of prosthetic prosthesis sharply decrease. Therefore, we recommend to produce zirconia occlusal surface or at least to combine the same materials, as it will increase the longevity of prosthetic appliance.

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Cytomorphometric Analysis of Inflammation Dynamics in the Periodontium Following the Use of Fixed Dental Prostheses

Molecules ◽

10.3390/molecules25204650 ◽

2020 ◽

Vol 25 (20) ◽

pp. 4650

Author(s):

Artak Heboyan ◽

Azeem Ul Yaqin Syed ◽

Dinesh Rokaya ◽

Paul R. Cooper ◽

Mikael Manrikyan ◽

...

Keyword(s):

Epithelial Cells ◽

Periodontal Diseases ◽

Cell Counts ◽

Dental Prostheses ◽

Computer Aided ◽

Metal Ceramic ◽

Before And After ◽

Cad Cam ◽

Fixed Dental Prostheses ◽

Cobalt Chrome

Cytomorphometry is used in the sampling of biological materials and diagnostic procedures. The use of cytological studies in periodontal diseases is not well described in the literature. Our study aimed to quantitatively assess the inflammation dynamics using cytomorphometric analysis of the periodontium before and after the use of fixed dental prostheses. Following ethics approval, a total of 105 subjects were divided in 3 groups as gingivitis (n = 23), periodontitis (n = 58), and healthy periodontium (control) (n = 24). The fixed dental prostheses (crowns and fixed partial dentures) were fabricated from cobalt-chrome metal-ceramic prostheses using the conventional method (C/M-CoCr), cobalt-chrome metal-ceramic prostheses by the computer-aided design and computer-aided manufacturing (CAD/CAM) technique (C/C-CoCr), and zirconia-based ceramic prostheses by the CAD/CAM technique (C/C-Zr) among subjects with gingivitis and periodontitis. The gingival crevicular fluid (GCF) was obtained from subjects before and after the use of the prostheses. The total count of epithelial cells and the connective tissue cells or polymorphonuclear neutrophils (PMNs) in GCF were studied using cytomorphometric analysis. The Statistical Package Tor the Social Sciences (SPSS), Version 20 (IBM Company, Chicago, IL, USA) was used to analyze the results and the significance level was set at p = 0.05. The data for before and after the use of the prostheses were compared using independent t-Tests. Similarly, the results after the use of prostheses in gingivitis, periodontitis, and control in each type of prostheses were compared using One-way ANOVA with post hoc using Scheffe. The total epithelial cells and the PMNs were determined along with the epithelium/leukocyte index. Regardless of the prostheses type used, no significant change in the parameters was identified among patients with a healthy periodontium, before and after prosthetic treatment. In all study groups, a statistically increase (p value < 0.05) was observed in the oral epithelial cell counts and a statistically decrease (p < 0.05) in the PMNs count following the use of the fixed prostheses. Data on cytomorphometric analysis could enable the selection of the most appropriate prostheses for use in patients with periodontal pathologies. When choosing prostheses, changes in the composition of GCF could be considered as a useful criterion for their use.

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Ultrastructural Lesions Produced by Alcohol and Sucrose in the Heart and Liver of C57BL Mice

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100068035 ◽

1970 ◽

Vol 28 ◽

pp. 208-209

Author(s):

K.K. SEKHRI ◽

C.S. ALEXANDER ◽

H.T. NAGASAWA

Keyword(s):

Osmium Tetroxide ◽

Male Mice ◽

Alcohol Group ◽

Group Iii ◽

Group I ◽

C57bl Mice ◽

Group Ii

C57BL male mice (Jackson Lab., Bar Harbor, Maine) weighing about 18 gms were randomly divided into three groups: group I was fed sweetened liquid alcohol diet (modified Schenkl) in which 36% of the calories were derived from alcohol; group II was maintained on a similar diet but alcohol was isocalorically substituted by sucrose; group III was fed regular mouse chow ad lib for five months. Liver and heart tissues were fixed in 2.5% cacodylate buffered glutaraldehyde, post-fixed in 2% osmium tetroxide and embedded in Epon-araldite.

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Heterogeneity and Immunochemical Properties of Anti-β2-glycoprotein I Autoantibodies

Thrombosis and Haemostasis ◽

10.1055/s-0037-1615218 ◽

1998 ◽

Vol 80 (09) ◽

pp. 393-398 ◽

Cited By ~ 33

Author(s):

V. Regnault ◽

E. Hachulla ◽

L. Darnige ◽

B. Roussel ◽

J. C. Bensa ◽

...

Keyword(s):

Fluid Phase ◽

Anticardiolipin Antibodies ◽

Dual Reactivity ◽

Group Iii ◽

Important Group ◽

Epitope Specificity ◽

Glycoprotein I ◽

Group I ◽

Group Ii ◽

Sufficient Concentration

SummaryMost anticardiolipin antibodies (ACA) associated with antiphospholipid syndrome (APS) are directed against epitopes expressed on β2-glycoprotein I (β2GPI). Despite a good correlation between standard ACA assays and those using purified human β2GPI as the sole antigen, some sera from APS patients only react in the latter. This is indicative of heterogeneity in anti-β2GPI antibodies. To characterize their reactivity profiles, human and bovine β2GPI were immobilized on γ-irradiated plates (β2GPI-ELISA), plain polystyrene precoated with increasing cardiolipin concentrations (CL/β2GPI-ELISA), and affinity columns. Fluid-phase inhibition experiments were also carried out with both proteins. Of 56 selected sera, restricted recognition of bovine or human β2GPI occurred respectively in 10/29 IgA-positive and 9/22 IgM-positive samples, and most of the latter (8/9) were missed by the standard ACA assay, as expected from a previous study. Based on species specificity and ACA results, IgG-positive samples (53/56) were categorized into three groups: antibodies reactive to bovine β2GPI only (group I) or to bovine and human β2GPI, group II being ACA-negative, and group III being ACA-positive. The most important group, group III (n = 33) was characterized by (i) binding when β2GPI was immobilized on γ-irradiated polystyrene or cardiolipin at sufficient concentration (regardless of β2GPI density, as assessed using 125I-β2GPI); (ii) and low avidity binding to fluid-phase β2GPI (Kd in the range 10–5 M). In contrast, all six group II samples showed (i) ability to bind human and bovine β2GPI immobilized on non-irradiated plates; (ii) concentration-dependent blockade of binding by cardiolipin, suggesting epitope location in the vicinity of the phospholipid binding site on native β2GPI; (iii) and relative avidities approximately 100-fold higher than in group III. Group I patients were heterogeneous with respect to CL/β2GPI-ELISA and ACA results (6/14 scored negative), possibly reflecting antibody differences in terms of avidity and epitope specificity. Affinity fractionation of 23 sera showed the existence, in individual patients, of various combinations of antibody subsets solely reactive to human or bovine β2GPI, together with cross-species reactive subsets present in all samples with dual reactivity namely groups III and II, although the latter antibodies were poorly purified on either column. Therefore, the mode of presentation of β2GPI greatly influences its recognition by anti-β2GPI antibodies with marked inter-individual heterogeneity, in relation to ACA quantitation and, possibly, disease presentation and pathogenesis.

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Oxygen Fraction Adjustment According to Body Surface Area during Extracorporeal Circulation

The Heart Surgery Forum ◽

10.1532/hsf.1325 ◽

2015 ◽

Vol 18 (3) ◽

pp. 098

Author(s):

Cem Arıtürk ◽

Serpil Ustalar Özgen ◽

Behiç Danışan ◽

Hasan Karabulut ◽

Fevzi Toraman

Keyword(s):

Body Temperature ◽

Surface Area ◽

Body Surface Area ◽

Body Surface ◽

Extracorporeal Circulation ◽

Group Iii ◽

Oxygen Fraction ◽

Arterial Blood ◽

Group I ◽

Group Ii

Background: The inspiratory oxygen fraction (FiO2) is usually set between 60% and 100% during conventional extracorporeal circulation (ECC). However, this strategy causes partial oxygen pressure (PaO2) to reach hyperoxemic levels (>180 mmHg). During anesthetic management of cardiothoracic surgery it is important to keep PaO2 levels between 80-180 mmHg. The aim of this study was to assess whether adjusting FiO2 levels in accordance with body temperature and body surface area (BSA) during ECC is an effective method for maintaining normoxemic PaO2 during cardiac surgery.Methods: After approval from the Ethics Committee of the University of Acıbadem, informed consent was given from 60 patients. FiO2 adjustment strategies applied to the patients in the groups were as follows: FiO2 levels were set as 0.21 × BSA during hypothermia and 0.21 × BSA + 10 during rewarming in Group I; 0.18 × BSA during hypothermia and 0.18 × BSA + 15 during rewarming in Group II; and 0.18 × BSA during hypothermia and variable with body temperature during rewarming in Group III. Arterial blood gas values and hemodynamic parameters were recorded before ECC (T1); at the 10th minute of cross clamp (T2); when the esophageal temperature (OT) reached 34°C (T3); when OT reached 36°C (T4); and just before the cessation of ECC (T5).Results: Mean PaO2 was significantly higher in Group I than in Group II at T2 and T3 (P = .0001 and P = .0001, respectively); in Group I than in Group III at T1 (P = .02); and in Group II than in Group III at T2, T3, and T4 (P = .0001 for all). Conclusion: Adjustment of FiO2 according to BSA rather than keeping it at a constant level is more appropriate for keeping PaO2 between safe level limits. However, since oxygen consumption of cells vary with body temperature, it would be appropriate to set FiO2 levels in concordance with the body temperature in the rewarming period.

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