Comparison of dental caries and periodontal disease with dermatoglyphic patterns and salivary p

Dermatoglyphic patterns are dermal ridge configurations present on the fingers, palm, toes and soles of human which are valuable in the diagnosis of many diseases associated with genetic disorders. Although the aetiology of dental caries and periodontal diseases is multi-factorial, we hypothesize that they may have genetic predisposition. We also evaluated its association with environmental factors like salivary pto assess any possible correlation. This study aims to Compare Dental caries (DC) and chronic generalized periodontitis (CGP) with Dermatoglyphic patterns and salivary p. One hundred patients were divided into group I (40 DC patients), group II (40 CGP patients) and group III includes 20 healthy controls. DMFT (decayed missing filled teeth) index (> 5) from group I, Russell’s periodontal index (2-5) from group II patients were taken. Finger print patterns by ink method and salivary p by p strips were recorded from all the groups and analysed with descriptive analysis. Group I showed more incidence of whorl patterns at lower salivary p than Group II and III which was statistically significant (p<0.05). Group II showed more incidence of ulnar loop patterns at slightly lower p than Group I & III which was statistically significant (p<0.05).The present study showed DC seen in people with more number of whorl patterns and periodontal disease with more ulnar loop patterns at lower salivary P. Larger scale studies are warranted to confirm our findings before applying dermatoglyphics to predict an individual prone to develop DC and periodontal disease in clinical practice.

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Characteristics of Periodontal Tissues in Prosthetic Treatment with Fixed Dental Prostheses

Molecules ◽

10.3390/molecules26051331 ◽

2021 ◽

Vol 26 (5) ◽

pp. 1331

Author(s):

Anna Avetisyan ◽

Marina Markaryan ◽

Dinesh Rokaya ◽

Marcos Roberto Tovani-Palone ◽

Muhammad Sohail Zafar ◽

...

Keyword(s):

Periodontal Diseases ◽

Group Iii ◽

Periodontal Tissues ◽

Dental Prostheses ◽

Group I ◽

Periodontal Index ◽

Computer Aided ◽

Cad Cam ◽

Group Ii ◽

Gingival Biotype

The objective of the present study was to investigate the effects of various types of fixed prostheses on periodontal tissues and explore the association of gingival biotype and gum recession in relation to prosthesis types. The study participants (N = 95) were divided into three groups based on the type of dental prosthesis: Group-I: cobalt-chrome (Co-Cr) ceramic prosthesis fabricated by the conventional method (n = 35); Group-II: consisted of patients with Co-Cr ceramic prostheses fabricated by a computer-aided design and computer aided manufacturing (CAD/CAM) technique (n = 30); and Group-III: zirconia-based prostheses fabricated by the CAD/CAM technique (n = 30). Following the use of prostheses, periodontal examinations were performed using the Community Periodontal Index (CPI) and Modified Approximal Plaque Index (MAPI). In addition, the gingival biotype was examined using a probe transparency method. The Statistical Package for the Social Sciences (SPSS), Version 20 (IBM Company, Chicago, IL, USA), was used to analyze the results, and the significance level was set at p = 0.05. It showed the MAPI results after the use of prosthetic rehabilitation for 12 months of periodontitis in 87.9% ± 15.4 of patients in Group-I, in 80.6% ± 17.97 in those in Group-II, and in 62.5% ± 21.4 in those in Group-III (p < 0.01). The CPI index results indicated a high prevalence of periodontal disease in all groups. The number of people with healthy periodontium constituted 17.1% of patients in Group-I, 24.2% in Group-II, and 37.1% in Group-III. Our study concluded that prosthetic treatment with periodontal diseases showed better outcomes while using dental prostheses fabricated by the CAD/CAM technique compared to the conventionally fabricated dental prostheses. The thin gingival biotype is more often associated with gingival recession than the thick biotype.

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The Relationship Between Dental Caries and YKL-40 Levels in Saliva

10.21203/rs.2.13390/v3 ◽

2020 ◽

Author(s):

Gülsüm Duruk ◽

Esra Laloglu

Keyword(s):

Dental Caries ◽

Group Iii ◽

Group I ◽

Pufa Index ◽

Icdas Ii ◽

Significant Difference ◽

Group Ii ◽

And Gender ◽

Post Hoc ◽

The Relationship

Abstract Objective : YKL-40, a new biomarker of localized inflammation, is secreted by macrophages and regulates inflammation and immune responses. The aim of this study was to investigate YKL-40 levels in saliva and compare the level of this mediator in healthy and unhealthy oral cavity. Methods: 85 children (46 girls, 39 boys), aged 6-15 (mean±SD: 9.15±2.16) were included in this study. The children were divided into three groups: Group-I (control, n=25, DMFT/dmft=0), Group-II (n=30, exist of localized dental caries) and Group-III (n=30, exist of localized advanced dental caries). Gingival index (GI), plaque index (PI), DMFT/dmft, DMFS/dmfs, and the number of advanced dental caries according to the ICDAS II and PUFA/pufa index were recorded. Saliva was collected and YKL-40 concentrations were measured. One-way ANOVA with Tukey post hoc, Kruskal-Wallis, multiple regression analysis, and Sperman’s correlation tests were used for statistical analysis. Results: The highest level of YKL-40 was obtained in group III , followed by groups II and I , respectively (p<0.01). In Group II, DMFT/dmft scores and the number of caries (DT/dt) were higher than in group III (p<0.01). In group III, there was a statistically significant correlation between YKL-40 levels in saliva and the number of advanced dental caries. In addition, there was no statistically significant difference in terms of age and gender (p>0.05). Conclusion: Advanced dental caries, rather than DMFT/dmft score, may play an important role in the increasing levels of YKL-40 in saliva.

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An Evaluation and Correlation of Leptin in Gingival Crevicular Fluid and Serum in Health, Gingivitis and Periodontitis

International Journal of Experimental Dental Science ◽

10.5005/jp-journals-10029-1023 ◽

2012 ◽

Vol 1 (2) ◽

pp. 93-97

Author(s):

Vinay Vadvadgi ◽

Neeta Padmawar

Keyword(s):

Periodontal Disease ◽

Gingival Crevicular Fluid ◽

Gingival Tissue ◽

Enzyme Linked Immunosorbent Assay ◽

Group Iii ◽

Group I ◽

The Mean ◽

Group Ii ◽

Crevicular Fluid ◽

Mean Concentration

ABSTRACT Background and objective Plasma leptin is associated in patients with inflammatory diseases. A high concentration of leptin is associated with healthy gingival tissue. The purpose of this study was to assess the concentration of human leptin in gingival crevicular fluid (GCF) and serum within healthy and diseased gingiva, further to explore the possibility of using the levels of leptin in GCF and serum as a biochemical marker of periodontal disease progression. Materials and methods Ninety subjects were selected with age (30-39 years) and sex (15 males and 15 females) matched, to eliminate age and sex as confounders. The subjects were divided into three groups consisting of 30 subjects in each group based on the clinical and radiological parameters; healthy (group I), gingivitis (group II), periodontitis (group III), from whom the GCF samples were collected with Periopaper GCF collection strips (Proflow, Amityville, NY, USA) for 30 seconds and blood samples with 20-gauge needle syringe respectively. Leptin concentration was determined from individual GCF and serum samples by enzyme-linked immunosorbent assay (ELISA). Results The highest mean leptin concentration in GCF was observed in group I (2,664.30 pg/ml ± 324.73) and least mean leptin concentration was obtained in group III (1,309.43 pg/ml ± 202.45). The mean concentration of group II (1,639.43 pg/ml ± 344.46) was intermediate between the highest and lowest values. In contrast, the highest mean leptin concentration in serum was obtained for group III (12,086.57 pg/ml ± 1,698.23) and least mean leptin concentration was obtained for group I (8,715.09 pg/ml ± 1,649.19). The mean concentration of the group II (10,694.01 pg/ml ± 1,777.72) were intermediate between the highest and lowest values. Conclusion The results indicated a statistically significant decrease in the GCF leptin concentration and increase in serum leptin concentration as the periodontal disease progressed. How to cite this article Vadvadgi VH, Saini R, Padmawar N. An Evaluation and Correlation of Leptin in Gingival Crevicular Fluid and Serum in Health, Gingivitis and Periodontitis. Int J Experiment Dent Sci 2012;1(2):93-97.

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Efficacy of hyaluronic acid in the treatment of chronic gingivitis in children

Vojnosanitetski pregled ◽

10.2298/vsp1112021i ◽

2011 ◽

Vol 68 (12) ◽

pp. 1021-1025

Author(s):

Marija Igic ◽

Dragan Mihailovic ◽

Ljiljana Kesic ◽

Mirjana Apostolovic ◽

Ljiljana Kostadinovic ◽

...

Keyword(s):

Hyaluronic Acid ◽

Control Group ◽

Treatment Needs ◽

Group Iii ◽

Group I ◽

Periodontal Index ◽

Before And After ◽

Community Periodontal Index ◽

Group Ii ◽

Basic Treatment

Introduction/Aim. Gingivitis is a common occurrence in children and may well be thought as a risk factor for the appearance and progression of the diseases of parodontal tissues. It is thus necessary to react in a timely and adequate fashion to prevent the disease to become serious and produce parodontopathy. The aim of the study was to establish the efficacy of hyaluronic acid in the treatment of chronic gingivitis in children. Methods. The study enrolled 130 children with permanent dentition. All of the examinees were divided into three groups: group I - 50 patients with chronic gingivitis in which only the basic treatment was applied; group II - 50 patients with chronic gingivitis in which hyaluronic acid was applied in addition to basic treatment; group III - 30 examinees with healthy gingiva (control group). Assessment of oral hygiene and status of the gingiva and parodontium was done using the appropriate indexes before and after the treatment. Inflammation of the gingiva was monitored by way of cytomorphometric studies. Results. The pretreatment values of the plaque index (PI) were high: in the group I PI was 1.94; in the group II PI was 1.68. After the treatment, the PI value was reduced to null in both groups (PI = 0). In the group III PI was 0.17. The bleeding index (BI) in the group I was 2.02 before and 0.32 after the treatment; the BI value in the group II was 1.74 before and 0.16 after the treatment. In the group III BI was 0. In the group I, the Community Periodontal Index of Treatment Needs (CPITN) was 1.66 before and 0.32 after the treatment; in the group II, the CPITN value was 1.5 before and 0.24 after the treatment. In the group III, the CPITN value was 0. In the group I, the size of the nuclei of the stratified squamous epithelium of the gingiva was reduced, although not so much as the nuclear size in the group II of examinees. Conclusion. Basic treatment is able to successfully treat chronic gingivitis in children. The use of hyaluronic acid together with the basic treatment can markedly improve the treatment effect.

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Interleukin-1β, interleukin-6 and tumour necrosis factor-alpha levels in blood and saliva in hypothyroidism accompanied with periodontitis

International Journal of Research in Pharmaceutical Sciences ◽

10.26452/ijrps.v10i2.539 ◽

2019 ◽

Vol 10 (2) ◽

pp. 1361-1366

Author(s):

Sahar H. Al-Hindawi ◽

Batool Hassan Al-Ghurabi

Keyword(s):

Immune Response ◽

Periodontal Disease ◽

Study Groups ◽

Control Group ◽

Necrosis Factor Alpha ◽

Group Iii ◽

Group I ◽

Salivary Level ◽

Tnf Α ◽

Group Ii

Relationship between thyroid dysfunction and periodontal disease has been mediated through an immune response. Cytokines are implicated in the initiation, consequences of immune response and a crucial role in the pathogenesis of thyroid disease, directly target thyroid follicular cells; and in the development and progression of periodontitis. This study aimed to detect cytokines levels which known to be associated with periodontitis in serum and saliva, to test the hypothesis that hypothyroidism influences the levels of biomarkers of periodontitis. Samples were collected from sixty patients with hypothyroid age ranged (20-64) years, thirty of patients were without periodontitis (group I) and 30 with periodontal disease (II); moreover, 30 subjects considered as control (group III) with age (20-53) years. Detection of cytokines was performed by ELISA. The results showed a significant elevation in serum and salivary levels of IL-1β (P<0.001) among patients’ groups (I and II) as compared to group III, as well IL-1β increase significantly in group II (P<0.001) than in group I and also than group III. There are non-significant differences (P>0.05) in serum level of IL-6 and TNF-α and salivary levels of TNF-α among all study groups. Nevertheless, the salivary level of IL-6 is increased significantly (P<0.05) in group II as compared with group I and group III, and their non-significant differences (P<0.05) between groups I and III. The present finding proposed that hypothyroidism might encourage periodontitis development; as well as serum and salivary levels of IL-1β, with salivary IL-6 may represent important biomarkers for the early detection of periodontitis in hypothyroid patients.

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Effect of Herbal and Fluoride Mouth Rinses onStreptococcus mutansand Dental Caries among 12–15-Year-Old School Children: A Randomized Controlled Trial

International Journal of Dentistry ◽

10.1155/2017/5654373 ◽

2017 ◽

Vol 2017 ◽

pp. 1-8 ◽

Cited By ~ 5

Author(s):

Vinej Somaraj ◽

Rekha P. Shenoy ◽

Ganesh Shenoy Panchmal ◽

Vijaya Kumar ◽

Praveen S. Jodalli ◽

...

Keyword(s):

Dental Caries ◽

Streptococcus Mutans ◽

Controlled Trial ◽

Group Iii ◽

Intention To Treat ◽

Group I ◽

Mouth Rinses ◽

Significant Difference ◽

Group Ii ◽

Glucan Synthesis

To assess and compare the effect of herbal and fluoride mouth rinses onStreptococcus mutanscount and glucan synthesis byStreptococcus mutansand dental caries, a parallel group placebo controlled randomized trial was conducted among 240 schoolchildren (12–15 years old). Participants were randomly divided and allocated into Group I (0.2% fluoride group), Group II (herbal group), and Group III (placebo group). All received 10 ml of respective mouth rinses every fortnight for a period of one year. Intergroup and intragroup comparison were done forStreptococcus mutanscount and glucan synthesis byStreptococcus mutansand dental caries.Streptococcus mutanscount showed a statistically significant difference between Group I and Group III (p=0.035) and also between Group II and Group III (p=0.039). Glucan concentration levels showed a statistically significant difference (p=0.024) between Group II and Group III at 12th month. Mean DMF scores showed no statistical difference between the three groups (p=0.139). No difference in the level of significance was seen in the intention-to-treat and per-protocol analysis. The present study showed that both herbal and fluoride mouth rinses, when used fortnightly, were equally effective and could be recommended for use in school-based health education program to control dental caries. Trial registration number isCTRI/2015/08/006070.

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COMPARATIVE EVALUATION OF THE BENEFITS OF ADJUNCTIVE USE OF LYCOPENE AND VITAMIN E IN NON-SURGICAL TREATMENT OF PERIODONTITIS : A RANDOMISED CLINICALAND MICROBIOLOGICAL STUDY

10.36106/ijsr/0517413 ◽

2020 ◽

pp. 3-5

Author(s):

Shrutika B. Borade ◽

Akshaya Banodkar ◽

Rajesh Gaikwad

Keyword(s):

Surgical Treatment ◽

Vitamin E ◽

Test Score ◽

Periodontal Diseases ◽

Group Iii ◽

Group I ◽

Group Ii ◽

Periodontal Healing ◽

Non Surgical Treatment ◽

Bana Test

Background-This study was aimed to compare and evaluate the benefits of adjunctive use of lycopene and vitamin E in the non-surgical treatment of periodontal diseases and effect of this treatment on the periodontal microflora. Methodology-Systemically healthy 30 chronic periodontitis patients were included in the study. periodontal examination was performed and BANA test score were obtained. patients were randomly divided into group-I, group-II and group-III. scaling and root planing was performed for all three groups. group-II and group-III were supplimented with lycopene (Lycostar) and Vit E(Evion 400mg)respectively for 1 month. PI, BOP, PPD, CAL and BANA test score were re-evaluated after 1 month. Result-Periodontal parameters and BANA test score were significantly reduced in both group-II and group-III as compared to group-I. Conclusion-Systemic administration of antioxidants improved periodontal healing and significantly reduced microbial load and can be used as an adjunct to non-surgical periodontal therapy.

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The Relationship Between Dental Caries and YKL-40 Levels in Saliva

10.21203/rs.2.13390/v2 ◽

2019 ◽

Author(s):

Gülsüm Duruk ◽

Esra Laloglu

Keyword(s):

Dental Caries ◽

Group Iii ◽

Group I ◽

Pufa Index ◽

Icdas Ii ◽

Significant Difference ◽

Group Ii ◽

And Gender ◽

Post Hoc ◽

The Relationship

Abstract Objective: YKL-40, a new biomarker of localized inflammation, is secreted by macrophages and regulates inflammation and immune responses. The aim of this study was to investigate YKL-40 levels in saliva and compare the level of this mediator in oral cavity. Methods: 85 children (46 girls, 39 boys), aged 6-15 (mean±SD: 9.15±2.16) were included in this study. The children were divided into three groups: Group-I (control, n=25, DMFT/dmft=0), Group-II (n=30, exist of localized dental caries) and Group-III (n=30, exist of localized advanced dental caries). Gingival index (GI), plaque index (PI), DMFT/dmft, DMFS/dmfs, and the number of advanced dental caries according to the ICDAS II and PUFA/pufa index were recorded. Saliva was collected and YKL-40 concentrations were measured. One-way ANOVA withTukey post hoc, Kruskal-Wallis, multiple regression analysis, and Sperman’s correlation tests were used for statistical analysis. Results: The highest level of YKL-40 was obtained in group III, followed by groups II and I, respectively (p<0.01). In Group II, DMFT/dmft scores and the number of caries (DT/dt) were higher than in group III (p<0.01). In group III, there was a statistically significant correlation between YKL-40 levels in saliva and the number of advanced dental caries. In addition, there was no statistically significant difference in terms of age and gender (p>0.05). Conclusion: Advanced dental caries, rather than DMFT/dmft score, may play an important role in the increasing levels of YKL-40 in saliva.

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Evaluating Salivary Alkaline Phosphatase Levels as a Biochemical Marker of Periodontal Disease in Periodontal Patients in a Tertiary Hospital in Nigeria

Journal of Periodontology & Implant Dentistry ◽

10.15171/jpid.2016.004 ◽

2018 ◽

Vol 8 (1) ◽

pp. 19-23

Author(s):

Adelegan Michael Adesakin ◽

Dosumu B. Elizabeth ◽

Opeodu O.I ◽

Arowojolu O. Modupe

Keyword(s):

Alkaline Phosphatase ◽

Periodontal Disease ◽

Biochemical Marker ◽

Early Stage ◽

Periodontal Diseases ◽

Tertiary Hospital ◽

Control Group ◽

Cross Sectional ◽

Group Iii ◽

Group I

Background and aims. Traditional methods of diagnosing periodontal diseases have their limitations, which include inability to provide information about the recent activity of the disease and difficulty in diagnosing the disease at an early stage when clinical changes have not started. This has necessitated the use of biomarkers designed to overcome these shortcomings. Materials and methods. A cross-sectional investigation was conducted among three groups of 27 participants each to assess the level of salivary alkaline phosphatase (SALP). The groups consisted of a control group (healthy) and two test groups (gingivitis and periodontitis). Saliva samples were collected and spectrophotometric analyses were carried out. Results. The highest mean SALP level (87.78 U/L) was found in group III, followed by group II (73.56 U/L), with group I exhibiting the least (38.89 U/L). The differences in the mean SALP between groups I and II, II and III, and I and III were statistically significant. Correlation between periodontal pockets depth and mean SALP was significant in group III. Conclusion. Variations in mean SALP levels among subjects with different periodontal conditions showed that mean SALP can differentiate various degrees of periodontal conditions and therefore has the potential to be used as a biochemical marker for periodontal disease.

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The Relationship Between Dental Caries and YKL-40 Levels in Saliva

10.21203/rs.2.13390/v1 ◽

2019 ◽

Author(s):

Gülsüm Duruk ◽

Esra Laloglu

Keyword(s):

Dental Caries ◽

Group Iii ◽

Group I ◽

Pufa Index ◽

Icdas Ii ◽

Significant Difference ◽

Group Ii ◽

And Gender ◽

Post Hoc ◽

The Relationship

Abstract Objective : YKL-40, a new biomarker of localized inflammation, is secreted by macrophages and regulates inflammation and immune responses. The aim of this study was to investigate YKL-40 levels in saliva and compare the level of this mediator in oral cavity. Methods: 85 children (46 girls, 39 boys), aged 6-15 (mean±SD: 9.15±2.16) were included in this study. The children were divided into three groups: Group-I (control, n=25, DMFT/dmft=0), Group-II (n=30, exist of localized dental caries) and Group-III (n=30, exist of localized advanced dental caries). Gingival index (GI), plaque index (PI), DMFT/dmft, DMFS/dmfs, and the number of advanced dental caries according to the ICDAS II and PUFA/pufa index were recorded. Saliva was collected and YKL-40 concentrations were measured. One-way ANOVA with Tukey post hoc , Kruskal-Wallis, multiple regression analysis, and Sperman’s correlation tests were used for statistical analysis. Results: The highest level of YKL-40 was obtained in group III , followed by groups II and I , respectively (p<0.01). In Group II, DMFT/dmft scores and the number of caries (DT/dt) were higher than in group III (p<0.01). In group III, there was a statistically significant correlation between YKL-40 levels in saliva and the number of advanced dental caries. In addition, there was no statistically significant difference, with respect to age and gender (p>0.05). Conclusion: Advanced dental caries, rather than DMFT/dmft score, may play an important role in the increasing levels of YKL-40 in saliva.

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