scholarly journals Lipid-Based Nanovesicular Drug Delivery Systems

Nanomaterials ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 3391
Author(s):  
Tania Limongi ◽  
Francesca Susa ◽  
Monica Marini ◽  
Marco Allione ◽  
Bruno Torre ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Extracellular Vesicles ◽  
Biochemical Composition ◽  
Drug Delivery Systems ◽  
Chemical Nature ◽  
Nanometer Scale ◽  
Pharmaceutical Chemical ◽  
The Past ◽  
Catanionic Vesicles ◽  
The Many

In designing a new drug, considering the preferred route of administration, various requirements must be fulfilled. Active molecules pharmacokinetics should be reliable with a valuable drug profile as well as well-tolerated. Over the past 20 years, nanotechnologies have provided alternative and complementary solutions to those of an exclusively pharmaceutical chemical nature since scientists and clinicians invested in the optimization of materials and methods capable of regulating effective drug delivery at the nanometer scale. Among the many drug delivery carriers, lipid nano vesicular ones successfully support clinical candidates approaching such problems as insolubility, biodegradation, and difficulty in overcoming the skin and biological barriers such as the blood–brain one. In this review, the authors discussed the structure, the biochemical composition, and the drug delivery applications of lipid nanovesicular carriers, namely, niosomes, proniosomes, ethosomes, transferosomes, pharmacosomes, ufasomes, phytosomes, catanionic vesicles, and extracellular vesicles.

The application progress of peptides in drug delivery systems in the past decade

2021 ◽  
Vol 66 ◽  
pp. 102880
Author(s):  
Bing Yang ◽  
Tian-tian Wang ◽  
Yu-shun Yang ◽  
Hai-liang Zhu ◽  
Jian-hua Li
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
The Past

scholarly journals Phenylboronic acid-decorated polymeric nanomaterials for advanced bio-application

2019 ◽  
Vol 8 (1) ◽  
pp. 548-561
Author(s):  
Tianyu Lan ◽  
Qianqian Guo
Keyword(s):  
Drug Delivery ◽  
Sialic Acid ◽  
Drug Delivery Systems ◽  
Phenylboronic Acid ◽  
Delivery Systems ◽  
Therapeutic Applications ◽  
The Past ◽  
Recent Advances

Abstract The paradigm of using phenylboronic acid-decorated polymeric nanomaterials for advanced bio-application has been well established over the past decade. Phenylboronic acid and its derivatives are known to form reversible complexes with polyols, including sugar, diol and diphenol. This unique chemistry of phenylboronic acid has given many chances to be exploited for diagnostic and therapeutic applications. This review highlights the recent advances in fabrication of phenylboronic acid-decorated polymeric nanomaterials, especially focus on the interactions with glucose and sialic acid. Applications of these phenylboronic acid-decorated nanomaterials in drug delivery systems and biosensors are discussed.

Functional Nanomaterials and Their Potential Applications in Antibacterial Therapy

2019 ◽  
Vol 7 (2) ◽  
pp. 129-146 ◽  
Author(s):  
Le Hong ◽  
Shu-Han Luo ◽  
Chen-Hao Yu ◽  
Yu Xie ◽  
Meng-Ying Xia ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Polymeric Nanoparticles ◽  
Lower Side ◽  
Functional Nanomaterials ◽  
Graphene Oxides ◽  
The Past ◽  
Potential Applications ◽  
Carbon Based Nanomaterials ◽  
Direct Use

In the past decades, nanomaterials have shown great potential in biomedical fields, especially in drug delivery, imaging and targeted therapy. Recently, the development of novel functional nanomaterials for antibacterial application has attracted much attention. Compared to the traditional direct use of antibiotics, antibacterial nanomaterials either as drug delivery systems or active agents have a higher efficacy and lower side effects. Herein, we will focus on the antibacterial applications of four commonly used nanomaterials, including metal-based nanomaterials, polymeric nanoparticles, graphene oxides or carbon-based nanomaterials and nanogels.

Functional peptide-based drug delivery systems

2020 ◽  
Vol 8 (31) ◽  
pp. 6517-6529 ◽  
Author(s):  
Zheng Lian ◽  
Tianjiao Ji
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
The Past ◽  
Functional Peptides ◽  
Functional Peptide ◽  
Smart Drug ◽  
Smart Drug Delivery

Representative strategies for designing smart drug delivery systems by using functional peptides in the past few years are highlighted in this review.

Advances in microfluidics for lipid nanoparticles and extracellular vesicles and applications in drug delivery systems

2018 ◽  
Vol 128 ◽  
pp. 84-100 ◽  
Author(s):  
Masatoshi Maeki ◽  
Niko Kimura ◽  
Yusuke Sato ◽  
Hideyoshi Harashima ◽  
Manabu Tokeshi
Keyword(s):  
Drug Delivery ◽  
Extracellular Vesicles ◽  
Drug Delivery Systems ◽  
Lipid Nanoparticles ◽  
Delivery Systems

Extracellular vesicles as drug delivery systems: Lessons from the liposome field

2014 ◽  
Vol 195 ◽  
pp. 72-85 ◽  
Author(s):  
Roy van der Meel ◽  
Marcel H.A.M. Fens ◽  
Pieter Vader ◽  
Wouter W. van Solinge ◽  
Omolola Eniola-Adefeso ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Extracellular Vesicles ◽  
Drug Delivery Systems ◽  
Delivery Systems

scholarly journals UNDERSTANDING NOVEL POLYMER AND LIPID BASED CARRIER SYSTEMS IN CLINICIAN PERSPECTIVE

2020 ◽  
Vol 4 (10) ◽  
Author(s):  
Kallem Sharat Venkat Reddy
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Drug Dosage ◽  
Delivery Systems ◽  
Review Article ◽  
Point Of View ◽  
Smart Polymers ◽  
The Past ◽  
Novel Drug ◽  
Carrier Systems

From the past two decades, technological advancements in science and chemistry made possible many new drug delivery systems that have the potential to completely change the course of routine therapeutic ways.  Lipid and polymer-based drug delivery systems are considered to be the pillars of many drug dosage forms, irrespective of their route of administration. With increasing knowledge on their chemistry, lipids and polymers are being modified and used as potential novel drug delivery systems with smart polymers and lipid nanotechnology paving the way for efficient drug delivery into the patient. This review article covers the swing of these drug delivery systems in the current market and interpreting all this from a health care professional’s point of view. Keywords: Gene delivery, Lipid based drug delivery, Polymer based drug delivery, Target specific drugs, Solid lipid nanoparticles

scholarly journals A mini-review of Nanocarriers in drug delivery systems Nanocarriers in drug delivery systems

2021 ◽  
Author(s):  
Mahsa Mazdaei ◽  
Kofi Asare-Addo
Keyword(s):  
Drug Delivery ◽  
Gene Delivery ◽  
Cancer Chemotherapy ◽  
Solid Lipid Nanoparticles ◽  
Drug Delivery Systems ◽  
Lipid Nanoparticles ◽  
Delivery Systems ◽  
Therapeutic Gene ◽  
Solid Lipid ◽  
The Past

The application of nanotechnology indrug delivery systems (DDS) has been researched widely and seen an advancementover the past three decades. Since the 1970s, nanoparticles were primarilyutilised in vaccine deliveries and cancer chemotherapy. In more recent years,they have been found to hold promises for broader applications such as inproteins and therapeutic gene delivery systems. To date, there have been only ahandful of nanocarrier-loaded drugs commercialised into the pharmaceuticalmarket. More research is thus needed to facilitate a breakthrough of theseproducts into the current market. This mini-review mainly focuses on four typesof commonly utilised organic nanocarriers including micelles, compactpolymerics, solid-lipid nanoparticles and liposomal vesicles and discusses theprogress and some challenges associated with these nanoparticles (NP). 

scholarly journals THE THE MICROEMULSION AS A KEY PLAYER IN CONQUERING THE SKIN BARRIER FOR THE AIM OF TRANSDERMAL DELIVERY OF DRUGS: REVIEWING A SUCCESSFUL DECADE

2019 ◽  
pp. 34-48
Author(s):  
RANIA YEHIA ◽  
DALIA A ATTIA
Keyword(s):  
Drug Delivery ◽  
Transdermal Delivery ◽  
Transdermal Drug Delivery ◽  
Drug Delivery Systems ◽  
Skin Barrier ◽  
The Other ◽  
Penetration Enhancers ◽  
The Past ◽  
Transdermal Drug Delivery Systems ◽  
The One

Microemulsion (ME) systems are now considered of the most successful transdermal drug delivery systems. This is due to their nanodroplets size in the one hand and to their composition that enables the use of several mechanistically penetration enhancers in the same formulation on the other hand. This work summarizes the types, properties, and the merits of the use of MEs for transdermal delivery and reviews the successful studies that were performed to deliver several drugs through this important route during the past 10–12 years.

Therapeutic Efficacy of Herbal Formulations Through Novel Drug Delivery Systems

2021 ◽  
pp. 1-42
Author(s):  
Arvind Kumar Singh Chandel ◽  
Nutan Bhingradiya
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Herbal Medicines ◽  
Bioactive Compound ◽  
Delivery Systems ◽  
Bioactive Molecules ◽  
Therapeutic Molecules ◽  
Dose Accuracy ◽  
The Many ◽  
Novel Drug

The herbal-based drugs have been getting wide attention over the last few decades. The herbal drugs have been used from the ancient times, but the dose accuracy, efficacy, and treatment was just based on symptomatic observatory. Modern research is focused on pure bioactive compound instead of crude. The researchers are trying to apply the current advanced nanotechnology-based knowledge on the herbal medicines to improve efficacy and reduces the unwanted pharmacological actions' adverse effects of the therapeutic molecules. The many novel drug delivery systems available used for the herbal bioactive molecules include polymeric micelle, injectable hydrogel, nano gel, nano emulsions, microsphere, polymeric nanoparticles, nano capsules, liposomes, phytosomes, transferosomes, dendrimer, and ethosomes. This chapter highlights the existing research and development of current standing of the of various novel formulations especially for the herbal bioactive molecules and summarizes their active ingredients, commercial formulations, route of drug administration, and pharmacological activity.

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