scholarly journals To Eat or Not to eat: A Review of the Relationship between Chocolate and Migraines

Nutrients ◽  
2020 ◽  
Vol 12 (3) ◽  
pp. 608 ◽  
Author(s):  
Magdalena Nowaczewska ◽  
Michał Wiciński ◽  
Wojciech Kaźmierczak ◽  
Henryk Kaźmierczak

Migraine is a chronic disorder with episodic attacks, and patients with a migraine often report that certain factors can trigger their headache, with chocolate being the most popular type of food-based trigger. Many studies have suggested a link between chocolate and headaches; however, the underlying physiological mechanisms are unclear. As premonitory symptoms may herald migraine attacks, a question arises regarding whether eating chocolate before a headache is a consequence of a food craving or indeed a real trigger. Here, we aim to summarize the available evidence on the relationship between chocolate and migraines. All articles concerning this topic published up to January 2020 were retrieved by searching clinical databases, including EMBASE, MEDLINE, PubMed, and Google Scholar. All types of studies have been included. Here, we identify 25 studies investigating the prevalence of chocolate as a trigger factor in migraineurs. Three provocative studies have also evaluated if chocolate can trigger migraine attacks, comparing it to a placebo. Among them, in 23 studies, chocolate was found to be a migraine trigger in a small percentage of participants (ranging from 1.3 to 33), while all provocative studies have failed to find significant differences between migraine attacks induced by eating chocolate and a placebo. Overall, based on our review of the current literature, there is insufficient evidence that chocolate is a migraine trigger; thus, doctors should not make implicit recommendations to migraine patients to avoid it.

Author(s):  
M.P. Sutunkova ◽  
B.A. Katsnelson ◽  
L.I. Privalova ◽  
S.N. Solovjeva ◽  
V.B. Gurvich ◽  
...  

We conducted a comparative assessment of the nickel oxide nanoparticles toxicity (NiO) of two sizes (11 and 25 nm) according to a number of indicators of the body state after repeated intraperitoneal injections of these particles suspensions. At equal mass doses, NiO nanoparticles have been found to cause various manifestations of systemic subchronic toxicity with a particularly pronounced effect on liver, kidney function, the body’s antioxidant system, lipid metabolism, white and red blood, redox metabolism, spleen damage, and some disorders of nervous activity allegedly related to the possibility of nickel penetration into the brain from the blood. The relationship between the diameter and toxicity of particles is ambiguous, which may be due to differences in toxicokinetics, which is controlled by both physiological mechanisms and direct penetration of nanoparticles through biological barriers and, finally, unequal solubility.


Transactions ◽  
2007 ◽  
Vol 4 (1) ◽  
pp. 8-17
Author(s):  
Margaret Stewart ◽  
Lynda Wilson

Author(s):  
Eman Tariq Alslman ◽  
Shaher H. Hamaideh ◽  
Manar Ali Bani Hani ◽  
Huda Mohammad Atiyeh

AbstractThe purpose of this article is to review the literature regarding the relationships between alexithymia, fibromyalgia (FM), and psychological distress among adolescents. Google Scholar and databases were searched using alexithymia, fibromyalgia, psychological distress, and adolescent keywords. Studies that examine the relationship between alexithymia and fibromyalgia and the contribution of psychological distress on this relationship among adolescents are lacking. However, based on previous studies on adult samples and theoretical background, there are possible relationship between alexithymia and fibromyalgia as well as possible mediating effect of psychological distress on this relationship in adolescents. Further studies are recommended to examine the relationships between alexithymia, fibromyalgia, and psychological distress among adolescents.


2018 ◽  
Vol 31 ◽  
pp. 120-124 ◽  
Author(s):  
Lauren E. Blau ◽  
Natalia C. Orloff ◽  
Amy Flammer ◽  
Carolyn Slatch ◽  
Julia M. Hormes

Nutrients ◽  
2018 ◽  
Vol 10 (12) ◽  
pp. 1956 ◽  
Author(s):  
Rebecca Lapides ◽  
Dennis Savaiano

Research evaluating the relationship between lactose intolerance (LI) symptoms and age, gender and race is reviewed. An exhaustive search was conducted on the Google Scholar and PubMed databases. The evidence suggests that women, the elderly or specific racial groups are not more susceptible to LI, but rather dose, body size and genetic differences in lactase non-persistence (LNP) are the primary drivers of intolerance symptoms.


2021 ◽  
Vol 22 (16) ◽  
pp. 8674
Author(s):  
Jia-Huang Chen ◽  
Chia-Hsien Wu ◽  
Chih-Kang Chiang

Pathological insults usually disturb the folding capacity of cellular proteins and lead to the accumulation of misfolded proteins in the endoplasmic reticulum (ER), which leads to so-called “ER stress”. Increasing evidence indicates that ER stress acts as a trigger factor for the development and progression of many kidney diseases. The unfolded protein responses (UPRs), a set of molecular signals that resume proteostasis under ER stress, are thought to restore the adaptive process in chronic kidney disease (CKD) and renal fibrosis. Furthermore, the idea of targeting UPRs for CKD treatment has been well discussed in the past decade. This review summarizes the up-to-date literature regarding studies on the relationship between the UPRs, systemic fibrosis, and renal diseases. We also address the potential therapeutic possibilities of renal diseases based on the modulation of UPRs and ER proteostasis. Finally, we list some of the current UPR modulators and their therapeutic potentials.


2020 ◽  
Vol 9 (8) ◽  
Author(s):  
Éber Coelho Paraguassu ◽  
Gabriela Victorelli ◽  
Maria Carolina Pelayo Teixeira ◽  
Almenara de Souza Fonseca Silva ◽  
Flávia Martão Flório

Introduction: Many career perspectives are available within the dental sciences and with the continued growth and consolidation of postgraduate in Brazil these perspectives are even greater. Objectives: This article aims to review the current literature on the professional trajectory of masters and PhDs egress from brazilian postgraduate in dentistry. Methodology: A search was carried out on the most prestigious indexing bases within the CAPES assessment, which is currently Scopus, Web of Sciences and Google Scholar. Only 5 articles were within the scope of this research and were eligible to compose this review. Conclusion: The current medical literature is very poor in terms of the professional trajectory of masters and PhDs egress from Brazilian postgraduate studies in dentistry. Other studies must be carried out so that there is a more reliable parameter for collection and comparison between different studies and only in this way can a more consistent conclusion on this topic be established.


Author(s):  
Diyas Indiastary ◽  
Noven Suprayogi ◽  
Imam Wahyudi Indrawan

This research attempts to study the determinants of third party funds on the Islamic banking in Indonesia with eight years of research from published journals in Indonesia. To reach the above objectives, investigation to check the relationship between promotion cost, inflation, GDP, interest rate, number of offices, and equivalent rate to third party funds on the Islamic banking in Indonesia is conducted. This research applies the meta-analysis technique to a sample of 34 articles with time variation from 2010-2018. The articles used are selected studies from Sinta Journal and Google Scholar databases. This research shows that promotion cost, number of offices, and equivalent rate have a significant correlation with third party funds on the Islamic banking in Indonesia. Meanwhile, inflation, GDP, and interest rate have no significant correlation with third party funds on the Islamic banking in Indonesia. The Findings from this study imply that if Islamic banks in Indonesia wish to enhance their third party fund, they must focus on internal indicators (promotion cost, number of offices, and equivalent rate), rather than looking at macro indicators.


e-CliniC ◽  
2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Jessica F. Rorrong ◽  
John J. E. Wantania ◽  
Anastasi M. Lumentut

Abstract: Nausea and vomiting are common problems in early pregnancy. Symptoms of nausea and vomiting in pregnant women that persist and get worse are called hyperemesis gravidarum. The causes of hyperemesis gravidarum are not exactly known, but it is supposed that they could be caused inter alia by psychological factors. This study was aimed to determine the relationship between the psychological state of pregnant women and the incidence of hyperemesis gravidarum. This was a literature review study by using three databases, namely Google Scholar, ClinicalKey, and Pubmed. The keywords used were psychological AND hyperemesis gravidarum. The result showed that the psychological conditions assessed in most literatures were anxiety disorders, depression, and stress. Pregnant women who suffered from anxiety and stress could trigger or worsen the depression. The higher level of anxiety would increase the chance of suffering from hyperemesis gravidarum. Therefore, pregnant women need additional psychological support during treatment and as a follow-up for pregnant women with hyperemesis gravidarum. In conclusion, the psychological state of pregnant women is related to the incidence of hyperemesis gravidarum.Keywords: psychological, hyperemesis gravidarum, nausea and vomiting Abstrak: Mual dan muntah merupakan masalah yang biasa terjadi pada awal kehamilan. Gejala mual dan muntah pada ibu hamil yang menetap dan bahkan bertambah berat disebut hiperemesis gravidarum. Faktor pemicu terjadinya hiperemesis gravidarum pada ibu hamil belum diketahui secara pasti, tetapi diperkirakan antara lain oleh faktor psikologis. Penelitian ini bertujuan untuk mengetahui hubungan keadaan psikologis ibu hamil dengan kejadian hiperemesis gravidarum. Jenis penelitian ialah literature review dengan pencarian data menggunakan tiga database yaitu Google Scholar, ClinicalKey, dan Pubmed. Kata kunci yang digunakan yaitu psikologis /psychological AND hiperemesis gravidarum/hyperemesis gravidarum. Hasil penelitian mendapatkan bahwa kondisi psikologis yang dinilai pada sebagian besar literatur yang dikaji ialah mengenai gangguan kecemasan, depresi, dan stres. Ibu hamil yang mengalami cemas dan stres dapat memicu atau memperburuk terjadinya depresi. Tingkat kecemasan yang semakin tinggi akan meningkatkan peluang untuk mengalami hiperemesis gravidarum sehingga diperlukan dukungan psikologis tambahan selama perawatan dan sebagai tindak lanjut ibu hamil dengan hiperemesis gravidarum. Simpulan penelitian ini ialah keadaan psikologis ibu hamil berhubungan dengan kejadian hiperemesis gravidarum. Kata kunci: psikologis, hiperemesis gravidarum, mual dan muntah


2010 ◽  
Vol 90 (9) ◽  
pp. 1345-1355 ◽  
Author(s):  
Joel E. Bialosky ◽  
Mark D. Bishop ◽  
Joshua A. Cleland

Physical therapists consider many factors in the treatment of patients with musculoskeletal pain. The current literature suggests expectation is an influential component of clinical outcomes related to musculoskeletal pain for which physical therapists frequently do not account. The purpose of this clinical perspective is to highlight the potential role of expectation in the clinical outcomes associated with the rehabilitation of individuals experiencing musculoskeletal pain. The discussion focuses on the definition and measurement of expectation, the relationship between expectation and outcomes related to musculoskeletal pain conditions, the mechanisms through which expectation may alter musculoskeletal pain conditions, and suggested ways in which clinicians may integrate the current literature regarding expectation into clinical practice.


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