scholarly journals Vitamin D Serum Levels in the UK Population, including a Mathematical Approach to Evaluate the Impact of Vitamin D Fortified Ready-to-Eat Breakfast Cereals: Application of the NDNS Database

Nutrients ◽  
2020 ◽  
Vol 12 (6) ◽  
pp. 1868
Author(s):  
Wim Calame ◽  
Laura Street ◽  
Toine Hulshof
Keyword(s):  
Vitamin D ◽  
Daily Intake ◽  
Serum Levels ◽  
Vitamin D Status ◽  
Nutrition Survey ◽  
Breakfast Cereals ◽  
Vitamin D Intake ◽  
The Uk ◽  
The Impact ◽  
The Relationship

Vitamin D status is relatively poor in the general population, potentially leading to various conditions. The present study evaluates the relationship between vitamin D status and intake in the UK population and the impact of vitamin D fortified ready-to-eat cereals (RTEC) on this status via data from the National Diet and Nutrition Survey (NDNS: 2008–2012). Four cohorts were addressed: ages 4–10 (n = 803), ages 11–18 (n = 884), ages 19–64 (n = 1655) and ages 65 and higher (n = 428). The impact of fortification by 4.2 μg vitamin D per 100 g of RTEC on vitamin D intake and status was mathematically modelled. Average vitamin D daily intake was age-dependent, ranging from ~2.6 (age range 4–18 years) to ~5.0 μg (older than 64 years). Average 25(OH)D concentration ranged from 43 to 51 nmol/L, the highest in children. The relationship between vitamin D intake and status followed an asymptotic curve with a predicted plateau concentration ranging from 52 in children to 83 nmol/L in elderly. The fortification model showed that serum concentrations increased with ~1.0 in children to ~6.5 nmol/L in the elderly. This study revealed that vitamin D intake in the UK population is low with 25(OH)D concentrations being suboptimal for general health. Fortification of breakfast cereals can contribute to improve overall vitamin D status.

scholarly journals Vitamin D Biofortification of Pork May Offer a Food-Based Strategy to Increase Vitamin D Intakes in the UK Population

2021 ◽  
Vol 8 ◽  
Author(s):  
Holly R. Neill ◽  
Chris I. R. Gill ◽  
Emma J. McDonald ◽  
W. Colin McRoberts ◽  
L. Kirsty Pourshahidi
Keyword(s):  
Vitamin D ◽  
Age Groups ◽  
Hypovitaminosis D ◽  
Ultraviolet B ◽  
Nutrition Survey ◽  
Additional Food ◽  
Vitamin D Intake ◽  
The Uk ◽  
Relative Change ◽  
The Impact

Hypovitaminosis D is prevalent worldwide, with many populations failing to achieve the recommended nutrient intake (RNI) for vitamin D (10–20 μg/day). Owing to low vitamin D intakes, limited exposure to ultraviolet-B (UVB) induced dermal synthesis, lack of mandatory fortification and poor uptake in supplement advice, additional food-based strategies are warranted to enable the UK population to achieve optimal vitamin D intakes, thus reducing musculoskeletal risks or suboptimal immune functioning. The aims of the current study were to (1) determine any changes to vitamin D intake and status over a 9-year period, and (2) apply dietary modeling to predict the impact of vitamin D biofortification of pork and pork products on population intakes. Data from the UK National Diet and Nutrition Survey (Year 1–9; 2008/09–2016/17) were analyzed to explore nationally representative mean vitamin D intakes and 25-hydroxyvitamin D (25(OH)D) concentrations (n = 13,350). Four theoretical dietary scenarios of vitamin D pork biofortification were computed (vitamin D content +50/100/150/200% vs. standard). Vitamin D intake in the UK population has not changed significantly from 2008 to 2017 and in 2016/17, across all age groups, 13.2% were considered deficient [25(OH)D <25 nmol/L]. Theoretically, increasing vitamin D concentrations in biofortified pork by 50, 100, 150, and 200%, would increase vitamin population D intake by 4.9, 10.1, 15.0, and 19.8% respectively. When specifically considering the impact on gender and age, based on the last scenario, a greater relative change was observed in males (22.6%) vs. females (17.8%). The greatest relative change was observed amongst 11–18 year olds (25.2%). Vitamin D intakes have remained stable in the UK for almost a decade, confirming that strategies are urgently required to help the population achieve the RNI for vitamin D. Biofortification of pork meat provides a proof of concept, demonstrating that animal-based strategies may offer an important contribution to help to improve the vitamin D intakes of the UK population, particularly adolescents.

scholarly journals Theoretical Impact of Replacing Whole Cow's Milk by Young-Child Formula on Nutrient Intakes of UK Young Children: Results of a Simulation Study

2015 ◽  
Vol 67 (4) ◽  
pp. 247-256 ◽  
Author(s):  
Simone R.B.M. Eussen ◽  
Josephine Pean ◽  
Leanne Olivier ◽  
Fabien Delaere ◽  
Anne Lluch
Keyword(s):  
Vitamin D ◽  
Young Child ◽  
Young Children ◽  
Saturated Fatty Acids ◽  
Daily Intake ◽  
Cow’S Milk ◽  
Nutrient Intakes ◽  
Nutrition Survey ◽  
Cow's Milk ◽  
The Uk

Background: Research into the role of young-child formulae (YCF) in a child's diet is limited and there is no consensual recommendation on its use. We evaluated the theoretical nutritional impact of replacing the existing practice of consuming cow's milk by YCF. Methods: From the UK Diet and Nutrition Survey of Infants and Young Children, whole cow's milk consumers, aged 12-18 months (n = 591) were selected for simulation scenarios. In Scenario 1, we tested the replacement of all whole cow's milk (434 ± 187 ml/day) by a matching volume of YCF, and in Scenario 2, all whole cow's milk was replaced by the on-pack recommended daily intake of 300 ml. Nutrient intakes before and after simulation scenarios were compared and evaluated against nutrient recommendations. Results: Intakes of protein and saturated fatty acids were significantly decreased, whereas essential fatty acid intakes were increased. The prevalence of nutrient inadequacy before simulation was 95.2% for vitamin D and 53.8% for iron. After simulation, inadequacy decreased to 4.9% (Scenario 1) and 0% (Scenario 2) for vitamin D and to 2.7% (Scenario 1) and 1.1% (Scenario 2) for iron. Conclusions: Replacement of habitual cow's milk intake by a matching volume or 300 ml of YCF may lead to nutritional intakes more in line with recommendations in young children.

scholarly journals Adequate Vitamin D Intake but Low Serum Levels in Pediatric Asthma Patients: A Pilot Study, Alberta Children’s Hospital

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Sarah Howe McKenna ◽  
Tanis R. Fenton ◽  
Mary Noseworthy ◽  
Mark Anselmo
Keyword(s):  
Vitamin D ◽  
Pediatric Asthma ◽  
Serum Levels ◽  
High Dose ◽  
Healthy Children ◽  
Vitamin D Status ◽  
Vitamin D Intake ◽  
Vitamin D Levels ◽  
Asthma Patients ◽  
25 Oh Vitamin D

Background. We assessed vitamin D intakes and serum 25(OH) vitamin D levels in pediatric asthma patients on moderate-to-high dose inhaled steroids and compared them to published findings of healthy children in our city.Methods. Parents and/or patients were interviewed to estimate the children’s vitamin D intakes from foods and supplements (using an adapted validated food frequency questionnaire) and asthma duration and management. Vitamin D status: serum 25-hyroxy vitamin D (25(OH)D) was obtained from the medical records.Results. Vitamin D intakes from food and supplements of the asthma patients (n=20, 742 ± 185 IU/day) were significantly higher compared to healthy Canadian children (n=1442, 229 ± 121 IU/day). Despite higher vitamin D intakes, the children had nonsignificantly lower serum 25(OH) vitamin D levels compared to the comparison group. Serum 25(OH)D levels increased by 3.6 nmol/L with each 100 IU of vitamin D intake (95% Confidence interval = 2.0–4.0,R2= 0.931, andp=0.001).Conclusion. Since adequate vitamin D status in asthma patients is necessary to support bone mineral accretion, it is important to achieve adequate vitamin D status by checking serum 25(OH)D status and supplement accordingly.

scholarly journals Vitamin D status of Irish adults: findings from the National Adult Nutrition Survey

2012 ◽  
Vol 109 (7) ◽  
pp. 1248-1256 ◽  
Author(s):  
Kevin D. Cashman ◽  
Siobhan Muldowney ◽  
Breige McNulty ◽  
Anne Nugent ◽  
Anthony P. FitzGerald ◽  
...  
Keyword(s):  
Vitamin D ◽  
Population Level ◽  
Institute Of Medicine ◽  
Vitamin D Status ◽  
Food Diary ◽  
Nutrition Survey ◽  
Blood Samples ◽  
Supplement Use ◽  
The Impact ◽  
Vitamin D Supplement

Previous national nutrition surveys in Irish adults did not include blood samples; thus, representative serum 25-hydroxyvitamin D (25(OH)D) data are lacking. In the present study, we characterised serum 25(OH)D concentrations in Irish adults from the recent National Adult Nutrition Survey, and determined the impact of vitamin D supplement use and season on serum 25(OH)D concentrations. Of the total representative sample (n1500, aged 18+ years), blood samples were available for 1132 adults. Serum 25(OH)D was measured via immunoassay. Vitamin D-containing supplement use was assessed by questionnaire and food diary. Concentrations of serum 25(OH)D were compared by season and in supplement users and non-users. Year-round prevalence rates for serum 25(OH)D concentration < 30, < 40, < 50 and < 75 nmol/l were 6·7, 21·9, 40·1 and 75·6 %, respectively (11·1, 31·1, 55·0 and 84·0 % in winter, respectively). Supplement users had significantly higher serum 25(OH)D concentrations compared to non-users. However, 7·5 % of users had winter serum 25(OH)D < 30 nmol/l. Only 1·3 % had serum 25(OH)D concentrations >125 nmol/l. These first nationally representative serum 25(OH)D data for Irish adults show that while only 6·7 % had serum 25(OH)D < 30 nmol/l (vitamin D deficiency) throughout the year, 40·1 % had levels considered by the Institute of Medicine as being inadequate for bone health. These prevalence estimates were much higher during winter time. While vitamin D supplement use has benefits in terms of vitamin D status, at present rates of usage (17·5 % of Irish adults), it will have only very limited impact at a population level. Food-based strategies, including fortified foods, need to be explored.

Vitamin D - From Essentiality to Functionality

2012 ◽  
Vol 82 (5) ◽  
pp. 321-326 ◽  
Author(s):  
Heike Bischoff-Ferrari
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Serum Levels ◽  
Vitamin D Status ◽  
Hydroxyvitamin D ◽  
Vitamin D Intake ◽  
Severe Deficiency ◽  
Normal Vitamin ◽  
25 Hydroxyvitamin D ◽  
Muscle Health

Vitamin D is essential in bone and muscle health. Severe deficiency (25-hydroxyvitamin D serum levels < 25 nmol/l) can result in rickets and osteomalacia, fractures, myopathy and falls. All recent recommendations on vitamin D agree that children and adults should reach a target 25-hydroxyvitamin D range of at least 50 nmol/l (threshold for normal vitamin D status) and 50 % of the population may be below that threshold. A vitamin D intake of 600 to 800 IU per day as recommended today will prevent about 97 % of children and adults from vitamin D deficiency. Notably, a higher 25-hydroxyvitamin D threshold of more than 60 nmol/l is needed for optimal functionality, fall and fracture in adults age 65 and older.

scholarly journals UK Food Standards Agency Workshop Consensus Report: the choice of method for measuring 25-hydroxyvitamin D to estimate vitamin D status for the UK National Diet and Nutrition Survey

2010 ◽  
Vol 104 (4) ◽  
pp. 612-619 ◽  
Author(s):  
Anne de la Hunty ◽  
A. Michael Wallace ◽  
Sigrid Gibson ◽  
Heli Viljakainen ◽  
Christel Lamberg-Allardt ◽  
...  
Keyword(s):  
Vitamin D ◽  
Expert Panel ◽  
Detailed Knowledge ◽  
Vitamin D Status ◽  
Nutrition Survey ◽  
Hydroxyvitamin D ◽  
Young Infants ◽  
Food Standards ◽  
25 Hydroxyvitamin D ◽  
The Uk

The consensus workshop, organised on behalf of the Food Standards Agency, was convened to recommend the most appropriate and secure method for measuring vitamin D status in the UK. Workshop participants (the Expert Panel) were invited on the basis of expertise in current 25-hydroxyvitamin D (25OHD) assays, or expertise in vitamin D nutrition and metabolism or detailed knowledge and experience in the National Diet and Nutrition Survey (NDNS). A decision support matrix, which set out the particular criteria by which the different options were scored and evaluated, was used to structure the discussion. The Expert Panel agreed that five methods for measuring 25OHD should be evaluated according to eleven criteria, selected on the basis of their relevance to the NDNS. All three of the evaluating subgroups of the Expert Panel produced similar total scores over the eleven criteria for the different methods; they scored LC–MS/MS and HPLC-UV similarly highly, while the scores for the immunoassay methods were lower. The Expert Panel recommended that an LC–MS/MS method should be the preferred method for the NDNS. A detailed specification for the method will be required to ensure comparability between NDNS and the National Health and Nutrition Examination Survey in the US facilitating future comparisons. The Expert Panel also recommended that the method should be carried out in a laboratory with appropriate expertise, competency and history of records of good performance. The method should be standardised against the National Institute of Standards and Technology SRM 972. If the recommended LC–MS/MS is adopted, the Expert Panel indicated that the method should be able to discriminate the C-3 epimer of 25OHD3, especially if used to measure 25OHD in young infants in the forthcoming Diet and Nutrition Survey of Infants and Young Children, who are known to have high circulating concentrations of the C-3 epimer.

scholarly journals Impact of diet on vitamin D status in a selected population of pregnant mothers in Sri Lanka

2018 ◽  
Vol 2 (1) ◽  
pp. 19
Author(s):  
Anusha Kaneshapillai ◽  
Guwani Liyanage ◽  
Usha Hettiaratchi
Keyword(s):  
Vitamin D ◽  
Sri Lanka ◽  
Indian Subcontinent ◽  
National Level ◽  
Daily Intake ◽  
High Rate ◽  
Dietary Vitamin ◽  
Vitamin D Status ◽  
Vitamin D Intake ◽  
Pregnant Mothers

Context: Results of various studies have shown severe vitamin D deficiency in the Indian subcontinent in all age groups and insufficiency in populations of South-East and East Asia.  There are no data available in Sri Lanka on vitamin D status in pregnant mothers. Vitamin D supplements are not provided routinely in state sector clinics. Institute of Medicine of the National Academy of Sciences in the USA recommends safe upper limit of dietary vitamin D as 4000 IU.Aims: Thus, our aim of this study was to assess vitamin D status and adequacy of vitamin D intake through diet among pregnant mothers.Settings and Design: This is a secondary analysis of data of a prospective cohort study.Methods and Material: 89 pregnant mothers in their 3rd trimester were recruited. Food frequency questionnaire based on 7-day estimated food record method was used. Analysis of blood sample was done for vitamin D, parathyroid hormone (PTH), calcium, inorganic phosphorous and alkaline phophatase levels.Statistical analysis used: Spearman’s correlation and independent sample t-test were performed.Results: We found that 12.4%, 50.6% and 37.1% were vitamin D deficient, insufficient and sufficient respectively. 25(OH)D and PTH showed a significant negative correlation (r=0.296; P<0.01).  Yet, serum PTH level was above the cut-off only among 4.5%. Further, only 13.5% subjects had high ALP (>240 IU/L). Average daily intake of vitamin D through diet was 1289.4 ± 1225.6 IU/day (range 56 IU- 5400 IU). Significant Main source of vitamin D was fortified milk powder and small fish.Conclusions: High rate of vitamin D insufficiency/deficiency was observed and this novel finding in our cohort suggests investigating vitamin D status in pregnant mothers at a national level. Vitamin D intake through diet was not adequate in our study sample. Further, rigorous trails are needed to evaluate the requirement for supplementation to optimise the bone metabolism during pregnancy in Sri Lanka.  

scholarly journals Iron intake and iron status of preschool children: associations with breakfast cereals, vitamin C and meat

1999 ◽  
Vol 2 (4) ◽  
pp. 521-528 ◽  
Author(s):  
Sigrid A Gibso
Keyword(s):  
Vitamin C ◽  
Iron Status ◽  
Dietary Intakes ◽  
Breakfast Cereal ◽  
Nutrition Survey ◽  
Iron Supplements ◽  
Breakfast Cereals ◽  
Nutritional Advice ◽  
The Uk ◽  
The Impact

AbstractObjective:To examine associations between breakfast cereal consumption and iron status and identify dietary patterns that might improve iron status in this vulnerable group.Design:Analysis of data from the UK National Diet and Nutrition Survey (NDNS) of children aged 1.5–4.5 years, including dietary intakes calculated from 4-day weighed records.Subjects:Data were used from 904 children with haematological measurements, excluding those taking iron supplements; 20% had low iron stores (ferritin < 10 μg l−1) while 8% were anaemic (Hb < 11 g dl−1).Results:High cereal consumers had significantly higher iron intakes than low cereal consumers (classified by tertiles) but the 10% difference in mean ferritin levels was not significant (P = 0.067). Lower intakes of vitamin C and meat among high consumers of cereal may have diluted the impact of cereal iron on iron status. When children were reclassified according to their intakes of vitamin C and iron from meat and breakfast cereals, the group with high (above median) intakes of two or more factors had a higher mean haemoglobin (Hb) level and a lower prevalence of anaemia compared with the group with low (below median) intakes of all three dietary constituents.Conclusions:Nutritional advice that aims to improve iron status should emphasize not only rich sources of iron but also factors that may enhance or inhibit absorption. Strategies to optimize iron status in this vulnerable age group include consuming an iron-fortified breakfast cereal, vitamin C-rich fruit or drink at breakfast, and avoiding tea with (or after) meals.

scholarly journals Associations between consumption of ready to eat cereal and nutrient intake in the United Kingdom

2020 ◽  
Vol 79 (OCE2) ◽  
Author(s):  
Yong Zhu ◽  
Jessica Smith ◽  
Neha Jain ◽  
Vipra Vanage ◽  
Mitesh Sharma ◽  
...  
Keyword(s):  
Vitamin D ◽  
United Kingdom ◽  
Nutrient Intake ◽  
Daily Intake ◽  
Level Energy ◽  
Food Diary ◽  
Nutrition Survey ◽  
Breakfast Cereals ◽  
High Fiber ◽  
The United Kingdom

AbstractIntroductionReady to eat cereal (RTEC) is a nutrient dense food in a typical western diet. Studies have reported better nutrient intake associated with RTEC consumption in other countries, however, little is known in the United Kingdom. The objective of the study was to examine consumption patterns of RTEC and to investigate associations between RTEC consumption and nutrient intake in a nationally representative sample in the United Kingdom.Materials and MethodsChildren aged 1.5–18 years old (N = 2564) and adults aged 19 years or older (N = 2705) from the National Diet and Nutrition Survey rolling programme 2012/13–2015/16 were included in the study. The average of four-day food diary data was used for analysis. RTEC included all food items from the high fiber breakfast cereals and other breakfast cereals, excluding porridge and instant hot oat cereals. Participants were classified as RTEC eaters if they reported consumption of RTEC at least once during the four days. Percentage contribution of RTEC to daily intake of nutrients in RTEC eaters was calculated. Differences in energy and nutrient intake between RTEC eaters and non-eaters were compared using multiple linear regression analyses for surveys, adjusting for age, gender, and equivalized income level. Energy intake was also included as a covariate in the analyses of nutrients intake.ResultsAbout 75% of children were RTEC eaters, whereas 52% of adults reported RTEC consumption. Their daily intake of RTEC were 35.1 g and 42.8 g, respectively. RTEC is a critical source of several key vitamins and minerals. For example, RTEC contributed to over 20% of daily intake of iron, folate, vitamin D, riboflavin, and thiamin in both children and adults who consumed RTEC. Compared to non-eaters, both child and adult RTEC eaters had significantly higher intake of total energy, carbohydrate, fiber, calcium, potassium, iron, phosphorus, magnesium, niacin, folate, riboflavin, thiamin, vitamin B6, vitamin B12, as well as significantly lower intake of sodium and total fat. Adult RTEC eaters also had higher intake of vitamin C and vitamin D. There was no difference in intake of non-milk extrinsic sugar by RTEC consumption status in both children and adults, although total sugar intake was higher in adult RTEC eaters.DiscussionRTEC is an important dietary source of key nutrients in the United Kingdom. Consumption of RTEC is associated with higher intake of nutrients to encourage and lower intake of nutrients to limit, in both children and adults in the United Kingdom.

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