scholarly journals Pharmacognostic Study on Elsholtzia ciliata (Thumb.) Hyl: Anatomy, Phytochemistry and Pharmacological Activities

2021 ◽  
Vol 14 (11) ◽  
pp. 1152
Author(s):  
Qian Zhang ◽  
Niara Moura Porto ◽  
Carolina Carvalho Guilhon ◽  
Thais Biondino Sardella Giorno ◽  
Daniela Sales Alviano ◽  
...  
Keyword(s):  
Quality Control ◽  
Chemical Constituents ◽  
Chemical Compounds ◽  
Anticancer Activities ◽  
Pharmacological Activities ◽  
Elsholtzia Ciliata ◽  
Nmr Techniques ◽  
Phytochemical Profile ◽  
Anti Inflammatory ◽  
Mtt Assays

Elsholtzia ciliata (Thunb.) Hyl, family Lamiaceae, is an important and popular anti-bacterial and anti-inflammatory Traditional Chinese Medicine (TCM). However, there are limited scientific studies on its anatomy and pharmacological activities. Moreover, the information of chemical constituents in relation to its non-volatile constituents are still missing. The current study aimed to evaluate the anatomic, pharmacological and phytochemical profile of Elsholtzia ciliata, providing means for the quality control of this herbal drug. The methodology designed for this study included the preparation of anatomic sections and their description, extraction, chromatography, structural elucidation of isolated compounds by NMR techniques and their quantification by HPLC using pharmacological assays (Formalin, hot plate, DPPH, antimicrobial-Gram positive, Gram Negative and fungus, and MTT assays) to confirm the activities described for this species. Results of the anatomic study are aligned with the pattern expected for plants belonging to the Lamiaceae family; Ursolic acid and Oroxylin were isolated from this plant species. The findings observed in this study indicate that Elsholtzia ciliata possess anti-inflammatory, antinociceptive, antioxidant, antimicrobial and anticancer activities. The chemical compounds isolated from its leaves and the anatomy profile of its parts provide the basis for further quality control for this plant.

scholarly journals TERMINALIA CHEBULA: SUCCESS FROM BOTANY TO ALLOPATHIC AND AYURVEDIC PHARMACY

2016 ◽  
Vol 9 (5) ◽  
pp. 21
Author(s):  
Varun Garg ◽  
Barinder Kaur ◽  
Sachin Kumar Singh ◽  
Bimlesh Kumar
Keyword(s):  
Chemical Constituents ◽  
Present Review ◽  
Terminalia Chebula ◽  
Pharmacological Activities ◽  
Therapeutic Uses ◽  
Anti Cancer ◽  
Anti Oxidant ◽  
Anti Inflammatory

ABSTRACTTerminalia chebula (TC) is a unique herb having various therapeutic potentials as anti-inflammatory, antioxidant, anticancer, and digestant. It belongsto family Combretaceae. In the present review, an attempt has been made to decipher classification, chemical constituents, therapeutic uses, andpatents that have been reported for TC. Various pharmacological activities of TC that make it as potential medicine and its Ayurvedic formulationsare highlighted.Keywords: Terminalia chebula, Anti-oxidant, Anti-cancer, Ayurvedic formulations, Anti-oxidant.

scholarly journals Demonstration of Phytochemicals and In-vitro Antioxidant and Anti-inflammatory activity by methanolic extract of Elettaria cardamomum

2020 ◽  
Vol 3 (3) ◽  
pp. 01-04
Author(s):  
Md. Shahidul Islam
Keyword(s):  
Methanolic Extract ◽  
Research Work ◽  
Inflammatory Activity ◽  
Pharmacological Activities ◽  
Elettaria Cardamomum ◽  
Ic50 Values ◽  
Phytochemical Profile ◽  
Anti Inflammatory ◽  
Dpph Scavenging

The existing research study attempts to untie novel avenues for development of the medicinal exercises of Elettaria cardamomum, fashionable known as the “Queen of Spices” and locally recognized as “elaichi”. Its seeds are utilized as abortifacient, acrid, alexiteric, aromatic, sweet, cardiac tonic, cooling, carminative, digestive, diuretic, expectorant, stimulant and also tonic beneficial in the asthma, haemorrhoids, bronchitis, strangury, renal in addition to vesical calculi, anorexia, halitosis, gastropathy dyspepsia as well as burning sensation. The prime goal of this research work is to evaluate antioxidant as well as anti-inflammatory properties of the traditional Bangladeshi medicinal extracts in addition to examine these activities. The aim in present work was to screen the phytochemical profile as well as pharmacological activities of the methanolic extract of this plant’s leaves. To explore pharmacological actions DPPH scavenging test and the HRBC membrane stabilization techniques were done for the antioxidant and also anti-inflammatory test respectively. The pharmacological works revealed that plant extracts might have noteworthy antioxidant effect which is possibly mediated by the inhibition of DPPH free radical which is accountable for oxidation. The IC50 values by the DPPH scavenging test observed for the standard and the leaves were 106.38µg/ml & 594.47µg/ml respectively. There is also moderate anti-inflammatory activity. The IC50 values for anti-inflammatory activity by standard & leaves were 35.04µg/ml and 944.0 µg/ml respectively.

scholarly journals Solidago virgaurea L.: A Review of Its Ethnomedicinal Uses, Phytochemistry, and Pharmacological Activities

Biomolecules ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. 1619
Author(s):  
Cornelia Fursenco ◽  
Tatiana Calalb ◽  
Livia Uncu ◽  
Mihaela Dinu ◽  
Robert Ancuceanu
Keyword(s):  
Chemical Constituents ◽  
Pharmacological Activities ◽  
Inflammatory Agent ◽  
Aerial Parts ◽  
Solidago Virgaurea ◽  
Clinical Models ◽  
Potential Benefits ◽  
Anti Inflammatory ◽  
Ethnomedicinal Uses ◽  
Published Research

Solidago virgaurea L. (European goldenrod, Woundwort), Asteraceae, is a familiar medicinal plant in Europe and other parts of the world, widely used and among the most researched species from its genus. The aerial parts of European goldenrod have long been used for urinary tract conditions and as an anti-inflammatory agent in the traditional medicine of different peoples. Its main chemical constituents are flavonoids (mainly derived from quercetin and kaempferol), C6-C1 and C6-C3 compounds, terpenes (mostly from the essential oil), and a large number of saponin molecules (mainly virgaureasaponins and solidagosaponins). Published research on its potential activities is critically reviewed here: antioxidant, anti-inflammatory, analgesic, spasmolitic, antihypertensive, diuretic, antibacterial, antifungal, antiparasite, cytotoxic and antitumor, antimutagenic, antiadipogenic, antidiabetic, cardioprotective, and antisenescence. The evidence concerning its potential benefits is mainly derived from non-clinical studies, some effects are rather modest, whereas others are more promising, but need more confirmation in both non-clinical models and clinical trials.

scholarly journals Shepherd’s Purse Polyphenols Exert Its Anti-Inflammatory and Antioxidative Effects Associated with Suppressing MAPK and NF-κB Pathways and Heme Oxygenase-1 Activation

2019 ◽  
Vol 2019 ◽  
pp. 1-14 ◽  
Author(s):  
Jinming Peng ◽  
Tianyong Hu ◽  
Jin Li ◽  
Jing Du ◽  
Kerui Zhu ◽  
...  
Keyword(s):  
Heme Oxygenase ◽  
Chemical Constituents ◽  
Chemical Compounds ◽  
Heme Oxygenase 1 ◽  
Mice Model ◽  
Traditional Herbal Medicine ◽  
Raw 264.7 Macrophages ◽  
Antioxidative Effects ◽  
Anti Inflammatory

Shepherd’s purse (Capsella bursa-pastoris (L.) Medik.), a wild herb as a traditional herbal medicine, has been proved with multiple healthy benefits. In this study, the chemical constituents of shepherd’s purse were identified by UPLC-QTOF-MS/MS. The antioxidative and anti-inflammatory potential of shepherd’s purse extract (SPE) were also investigated applying lipopolysaccharide- (LPS-) induced inflammation in RAW 264.7 macrophages and a carrageenan-induced mice paw edema model. Twenty-four chemical compounds were identified mainly including phenolic acids and flavonoids. The data also indicated SPE inhibited the productions of NO, PGE2, TNF-α, and IL-6 stimulated with LPS. In addition, SPE inhibited the increase of reactive oxygen species (ROS) and upregulated the expression of heme oxygenase-1 (HO-1). We further found that SPE inhibited the phosphorylation of P38 MAPK and activation of NF-κB. In vivo mice model also indicated that SPE showed strong antioxidative and anti-inflammatory activity.

scholarly journals Traditional Uses, Phytochemistry, and Pharmacology of Elegia Species: A Review

2021 ◽  
Vol 90 (1) ◽  
pp. 4
Author(s):  
Panagiotis Lymperis ◽  
Ekaterina-Michaela Tomou ◽  
Marco Nuno De Canha ◽  
Namrita Lall ◽  
Helen Skaltsa
Keyword(s):  
Biological Activities ◽  
Chemical Constituents ◽  
Pharmacological Activities ◽  
Traditional Uses ◽  
Comprehensive Search ◽  
Extensive Information ◽  
The Subject ◽  
Phytochemical Profile ◽  
Ecological Dominance ◽  
New Research

In South Africa, plants belonging to the Restionaceae family possess an ecological dominance. As a result, they have been the subject of numerous morphological, anatomical, and evolutionary studies. However, few studies have focused on their phytochemical profile and their potential pharmacological activities. The genus Elegia L. is the second largest of this family comprising 52 species, which are mainly used as materials for thatching. Limited studies on the chemical constituents of Elegia species and their importance as medicinal plants have been undertaken. This review provides constructive and extensive information about the botanical characterization, distribution, traditional uses, phytochemistry and pharmacology of the genus Elegia. A comprehensive search of previously published literature was performed for studies on this genus, using databases with different key search words. This survey documented 52 Elegia species summarizing their previous taxonomic classification. In addition, 14 species were found to be studied for their phytochemical profile, revealing 14 chemical compounds. Concerning their biological activities, only one species (E. tectorum (L.f.) Moline and H.P.Linder) is reported for its anti-wrinkle activity. Moreover, two species are locally used for thatching and as materials for brooms. The present review highlights the Elegia genus as an important source of bioactive phytochemicals with flavonol glycosides being the main metabolites and reveals the uncharted territory of this genus for new research studies.

scholarly journals Chemical Constituents and Pharmacological Activities of Garlic (Allium sativum L.): A Review

Nutrients ◽  
2020 ◽  
Vol 12 (3) ◽  
pp. 872 ◽  
Author(s):  
Gaber El-Saber Batiha ◽  
Amany Magdy Beshbishy ◽  
Lamiaa G. Wasef ◽  
Yaser H. A. Elewa ◽  
Ahmed A. Al-Sagan ◽  
...  
Keyword(s):  
Allium Sativum ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Biological Properties ◽  
Herbaceous Plant ◽  
Anticancer Activities ◽  
Active Constituent ◽  
Pharmacological Activities ◽  
Traditional Medicines ◽  
Traditional Remedy

Medicinal plants have been used from ancient times for human healthcare as in the form of traditional medicines, spices, and other food components. Garlic (Allium sativum L.) is an aromatic herbaceous plant that is consumed worldwide as food and traditional remedy for various diseases. It has been reported to possess several biological properties including anticarcinogenic, antioxidant, antidiabetic, renoprotective, anti-atherosclerotic, antibacterial, antifungal, and antihypertensive activities in traditional medicines. A. sativum is rich in several sulfur-containing phytoconstituents such as alliin, allicin, ajoenes, vinyldithiins, and flavonoids such as quercetin. Extracts and isolated compounds of A. sativum have been evaluated for various biological activities including antibacterial, antiviral, antifungal, antiprotozoal, antioxidant, anti-inflammatory, and anticancer activities among others. This review examines the phytochemical composition, pharmacokinetics, and pharmacological activities of A. sativum extracts as well as its main active constituent, allicin.

Chrysanthemum indicum L.: A Comprehensive Review of its Botany, Phytochemistry and Pharmacology

2020 ◽  
Vol 48 (04) ◽  
pp. 871-897 ◽  
Author(s):  
Yanhao Shao ◽  
Yunda Sun ◽  
Ding Li ◽  
Yiping Chen
Keyword(s):  
Quality Control ◽  
Chinese Medicine ◽  
Resource Availability ◽  
Immune Regulation ◽  
Chemical Constituents ◽  
Pharmacological Activities ◽  
Comprehensive Review ◽  
Perennial Plant ◽  
Chrysanthemum Indicum ◽  
Hepatoprotective Effects

Chrysanthemum indicum L. (C. indicum L.), a member of the Compositae family, is a perennial plant that has been used as a traditional medicine for more than 2000 years in China and is widely used for the treatment of Pemphigus, swelling, pain, and scrofula. To date, more than 190 chemical constituents have been isolated and identified from this plant, including flavonoids, terpenoids, phenylpropanoids, and phenolic acids. Numerous modern studies have shown that extracts or monomeric compounds from C. indicum L. have several pharmacological activities, such as anti-inflammatory anti-oxidation, antipathogenic microorganism, anticancer, immune regulation, and hepatoprotective effects. However, resource availability, the research on the mechanism, and quality control are still insufficient, which deserves further efforts. In this paper, the advances in botany, phytochemistry, and pharmacology of C. indicum L were reviewed. We hope that this review can provide important information for traditional Chinese medicine, phytochemistry, synthetic and medicinal chemistry researchers for making full use of C. indicum L. resource.

scholarly journals Characterization by GC-MS of the Main Ethanolic Extract’S Components from the Bark of Talipariti elatum Sw. (Fryxell) Malvaceae

2018 ◽  
Vol 6 (2) ◽  
pp. 1
Author(s):  
José González ◽  
Armando Cuéllar ◽  
Enrique Gómez ◽  
Julio Pérez ◽  
Max Monan
Keyword(s):  
Quality Control ◽  
Crude Extract ◽  
Mass Spectra ◽  
Chemical Constituents ◽  
Ethanolic Extract ◽  
Soxhlet Extraction ◽  
Chemical Compounds ◽  
Chemical Components ◽  
Analytical Technique ◽  
First Time

Talipariti elatum (Sw.), commonly named Blue Mahoe, is used as antasthmatic, antitussive, against catarrh and expectorant in phytotherapy in Cuba, although the plants’ composition has not been determined in detail so far. An ethanolic extract from the bark of Talipariti elatum Sw. (Fryxell) Malvaceae that grows in Cuba was prepared by Soxhlet extraction with ethanol at 95% during 20 hours. The crude extract without purification was analyzed using a GCMS-QP2010 Ultra Shimadzu, and the components were identified by comparing their retention times and their mass spectra with those of NIST21Library. About 45 different chemical compounds were detected in the sample and from them, 31 chemical components were characterized and reported for the first time from Talipariti elatum. Our results demonstrate the developed method could be employed as a rapid and versatile analytical technique for identification of chemical constituents and quality control of Talipariti samples.

scholarly journals Chemical Constituents fromDaphne giraldiiNitsche and Their Contents Simultaneous Determination by HPLC

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Huyiligeqi ◽  
Xiaoxv Dong ◽  
Chunjing Yang ◽  
Guanling Xu ◽  
Sali Cao ◽  
...  
Keyword(s):  
Simultaneous Determination ◽  
Reliable Method ◽  
Chemical Constituents ◽  
Folk Medicine ◽  
Anticancer Activities ◽  
Isolation And Characterization ◽  
Anti Inflammatory

Daphne giraldiiNitsche (Thymelaeaceae) is widely distributed in the Chinese provinces of Shaanxi, Gansu, and Qinghai, which has been used in Chinese folk medicine to treat ache and rheumatism. Pharmacologic tests have revealed that the plant has anti-inflammatory, analgesic, and anticancer activities. However, there is still not enough systemic investigation on the chemical constituents and the method for the contents simultaneous determination inD. giraldii. Therefore, the isolation and characterization of the compounds from the stem barks of this plant were reported. Moreover, a facile, accurate, and reliable method has been developed and validated for their simultaneous determination using HPLC-DAD.

scholarly journals The combination of two natural medicines, Chuanxiong and Asarum: A review of the chemical constituents and pharmacological activities

2021 ◽  
pp. 174751982110391
Author(s):  
Qingcheng Yang ◽  
Fangli Shen ◽  
Fengqin Zhang ◽  
Xue Bai ◽  
Yanru Zhang ◽  
...  
Keyword(s):  
Chemical Constituents ◽  
Experimental Studies ◽  
Chemical Components ◽  
Therapeutic Effects ◽  
Anticancer Activities ◽  
Volatile Oils ◽  
Pharmacological Activities ◽  
Single Drug ◽  
Traditional Natural ◽  
Natural Medicines

Traditional Chinese medicine has been clinically used in China for many years, with experimental studies and clinical trials having demonstrated that it is safe and valid. Among many traditional natural medicines, Chuanxiong and Asarum have been proven to be effective in the treatment of relieving pain. Actually, as well as analgesic, they have common attributes, such as anti-inflammatory, cardiovascular benefits, and anticancer activities, with volatile oils being their major components. Furthermore, Chuanxiong and Asarum have been combined as drug pairs in the same prescription for thousands of years, with examples being Chuanxiong Chatiao San and Chuanxiongxixintang. More interestingly, their combination has better therapeutic effects on diseases than a single drug. After the combination of Chuanxiong and Asarum forms a blend, a series of changes take place in their chemical components, such as the contents of the main active ingredients, ferulic acid and ligustilide, increased significantly after this progress. At the same time, the pharmacological effects of the combination appearing to be more powerful, such as synergistic analgesic. This review focuses on the chemical constituents and pharmacological activities of Chuanxiong, Asarum, and Chuanxiong Asarum compositions.

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