scholarly journals Mathematical Model of COVID-19 Transmission Dynamics in South Korea: The Impacts of Travel Restrictions, Social Distancing, and Early Detection

Processes ◽  
2020 ◽  
Vol 8 (10) ◽  
pp. 1304
Author(s):  
Byul Nim Kim ◽  
Eunjung Kim ◽  
Sunmi Lee ◽  
Chunyoung Oh

The novel coronavirus disease (COVID-19) poses a severe threat to public health officials all around the world. The early COVID-19 outbreak in South Korea displayed significant spatial heterogeneity. The number of confirmed cases increased rapidly in the Daegu and Gyeongbuk (epicenter), whereas the spread was much slower in the rest of Korea. A two-patch mathematical model with a mobility matrix is developed to capture this significant spatial heterogeneity of COVID-19 outbreaks from 18 February to 24 March 2020. The mobility matrix is taken from the movement data provided by the Korea Transport Institute (KOTI). Some of the essential patch-specific parameters are estimated through cumulative confirmed cases, including the transmission rates and the basic reproduction numbers (local and global). Our simulations show that travel restrictions between the epicenter and the rest of Korea effectively prevented massive outbreaks in the rest of Korea. Furthermore, we explore the effectiveness of several additional strategies for the mitigation and suppression of Covid-19 spread in Korea, such as implementing social distancing and early diagnostic interventions.

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
G. B. Almeida ◽  
T. N. Vilches ◽  
C. P. Ferreira ◽  
C. M. C. B. Fortaleza

AbstractIn 2020, the world experienced its very first pandemic of the globalized era. A novel coronavirus, SARS-CoV-2, is the causative agent of severe pneumonia and has rapidly spread through many nations, crashing health systems and leading a large number of people to death. In Brazil, the emergence of local epidemics in major metropolitan areas has always been a concern. In a vast and heterogeneous country, with regional disparities and climate diversity, several factors can modulate the dynamics of COVID-19. What should be the scenario for inner Brazil, and what can we do to control infection transmission in each of these locations? Here, a mathematical model is proposed to simulate disease transmission among individuals in several scenarios, differing by abiotic factors, social-economic factors, and effectiveness of mitigation strategies. The disease control relies on keeping all individuals’ social distancing and detecting, followed by isolating, infected ones. The model reinforces social distancing as the most efficient method to control disease transmission. Moreover, it also shows that improving the detection and isolation of infected individuals can loosen this mitigation strategy. Finally, the effectiveness of control may be different across the country, and understanding it can help set up public health strategies.


Author(s):  
Eunha Shim ◽  
Amna Tariq ◽  
Wongyeong Choi ◽  
Yiseul Lee ◽  
Gerardo Chowell

AbstractSince the first identified individual of 2019 novel coronavirus (COVID-19) infection on Jan 20, 2020 in South Korea, the number of confirmed cases rapidly increased. As of Feb 26, 2020, 1,261 cases of COVID-19 including 12 deaths were confirmed in South Korea. Using the incidence data of COVID-19, we estimate the reproduction number at 1.5 (95% CI: 1.4-1.6), which indicates sustained transmission and support the implementation of social distancing measures to rapidly control the outbreak.


2021 ◽  
Vol 149 ◽  
Author(s):  
Wenning Li ◽  
Jianhua Gong ◽  
Jieping Zhou ◽  
Lihui Zhang ◽  
Dongchuan Wang ◽  
...  

Abstract In December 2019, the first confirmed case of pneumonia caused by a novel coronavirus was reported. Coronavirus disease 2019 (COVID-19) is currently spreading around the world. The relationships among the pandemic and its associated travel restrictions, social distancing measures, contact tracing, mask-wearing habits and medical consultation efficiency have not yet been extensively assessed. Based on the epidemic data reported by the Health Commission of Wenzhou, we analysed the developmental characteristics of the epidemic and modified the Susceptible-Exposed-Infectious-Removed (SEIR) model in three discrete ways. (1) According to the implemented preventive measures, the epidemic was divided into three stages: initial, outbreak and controlled. (2) We added many factors, such as health protections, travel restrictions and social distancing, close-contact tracing and the time from symptom onset to hospitalisation (TSOH), to the model. (3) Exposed and infected people were subdivided into isolated and free-moving populations. For the parameter estimation of the model, the average TSOH and daily cured cases, deaths and imported cases can be obtained through individual data from epidemiological investigations. The changes in daily contacts are simulated using the intracity travel intensity (ICTI) from the Baidu Migration Big Data platform. The optimal values of the remaining parameters are calculated by the grid search method. With this model, we calculated the sensitivity of the control measures with regard to the prevention of the spread of the epidemic by simulating the number of infected people in various hypothetical situations. Simultaneously, through a simulation of a second epidemic, the challenges from the rebound of the epidemic were analysed, and prevention and control recommendations were made. The results show that the modified SEIR model can effectively simulate the spread of COVID-19 in Wenzhou. The policy of the lockdown of Wuhan, the launch of the first-level Public Health Emergency Preparedness measures on 23 January 2020 and the implementation of resident travel control measures on 31 January 2020 were crucial to COVID-19 control.


Fractals ◽  
2020 ◽  
Vol 28 (08) ◽  
pp. 2040026 ◽  
Author(s):  
YOLANDA GUERRERO SÁNCHEZ ◽  
ZULQURNAIN SABIR ◽  
JUAN L. G. GUIRAO

The aim of the present paper is to state a simplified nonlinear mathematical model to describe the dynamics of the novel coronavirus (COVID-19). The design of the mathematical model is described in terms of four categories susceptible ([Formula: see text], infected ([Formula: see text], treatment ([Formula: see text] and recovered ([Formula: see text], i.e. SITR model with fractals parameters. These days there are big controversy on if is needed to apply confinement measure to the population of the word or if the infection must develop a natural stabilization sharing with it our normal life (like USA or Brazil administrations claim). The aim of our study is to present different scenarios where we draw the evolution of the model in four different cases depending on the contact rate between people. We show that if no confinement rules are applied the stabilization of the infection arrives around 300 days affecting a huge number of population. On the contrary with a contact rate small, due to confinement and social distancing rules, the stabilization of the infection is reached earlier.


Author(s):  
Fakhar Shahzad ◽  
Jianguo Du ◽  
Imran Khan ◽  
Zeeshan Ahmad ◽  
Muhammad Shahbaz

Social distancing has manifold effects and is used as a non-pharmacological measure to respond to pandemic situations such as the novel coronavirus (COVID-19), especially in the absence of vaccines and other useful antiviral drugs. Governments around the globe have adopted and implemented a series of social distancing strategies. The efficacy of various policies and their comparative influence on mechanisms led by public actions and adoptions have not been examined. The differences in types and effective dates of various social distancing policies in various provinces/territories of Pakistan constitute a pure ground to examine the causal effects of each COVID-19 policy. Using the location trends and population movement data released by Google, a quasi-experimental method was used to measure the impact of the government’s various social distancing policies on the people’s existence at home and their outside social mobility. Based on the magnitude and importance of policy influences, this research ranked six social distancing policies whose influence exceeded the effect of voluntary behavior. Our research outcomes describe that the trend of staying at home was firmly pushed by state-wide home order rather than necessary business closings and policies that were associated with public gathering restrictions. Strong government policies have a strong causal effect on reducing social interactions.


2020 ◽  
Vol 32 (6-7) ◽  
pp. 360-362 ◽  
Author(s):  
Sunhee Park ◽  
Beomsoo Kim ◽  
Jaeil Lee

The novel coronavirus disease (COVID-19) outbreak has put the entire world in a pandemic situation. In response, strict screening, quarantine protocols, and contact tracing have been conducted in South Korea. The purpose of this study was to examine effects of social distancing on the Public Bicycle Sharing System (PBSS) during the COVID-19 outbreak. We used the PBSS public dataset of Seoul, South Korea. Difference-in-differences (DID) analysis was used. In the DID approach, the 2 groups are distinguished based on designated year. Cases of PBSS use were observed in 2 time periods: pre- and post-strict social distancing in Seoul, Korea. Average PBSS usage per day doubled during 2019-2020 (30 697 vs 77 996, P < .001). Commuters and weekend users increased during the social distancing period in 2020 compared with the same period in 2019. DID analysis showed statistically significant positive effects of high levels of social distancing on PBSS usage, commuters, weekend users, and new subscribers. In conclusion, social distancing during the COVID-19 outbreak increased outdoor physical activity. Meaningful outdoor physical activity during the COVID-19 pandemic can be safe from infection and psychologically stabilized as long as keeping meticulous physical distancing, such as hand hygiene, wearing facial masks, and surface cleaning of public resources.


Author(s):  
Ka Chun Chong ◽  
Wei Cheng ◽  
Shi Zhao ◽  
Feng Ling ◽  
Kirran N. Mohammad ◽  
...  

AbstractWe monitored the transmissibility of 2019 novel coronavirus disease in Zhejiang accounting the transmissions from imported cases. Even though Zhejiang is one of the worst-affected provinces, an interruption of disease transmission (i.e. instantaneous reproduction numbers <1) was observed in early/mid-February after an early social-distancing response to the outbreak.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Meng-Chun Chang ◽  
Rebecca Kahn ◽  
Yu-An Li ◽  
Cheng-Sheng Lee ◽  
Caroline O. Buckee ◽  
...  

Abstract Background As COVID-19 continues to spread around the world, understanding how patterns of human mobility and connectivity affect outbreak dynamics, especially before outbreaks establish locally, is critical for informing response efforts. In Taiwan, most cases to date were imported or linked to imported cases. Methods In collaboration with Facebook Data for Good, we characterized changes in movement patterns in Taiwan since February 2020, and built metapopulation models that incorporate human movement data to identify the high risk areas of disease spread and assess the potential effects of local travel restrictions in Taiwan. Results We found that mobility changed with the number of local cases in Taiwan in the past few months. For each city, we identified the most highly connected areas that may serve as sources of importation during an outbreak. We showed that the risk of an outbreak in Taiwan is enhanced if initial infections occur around holidays. Intracity travel reductions have a higher impact on the risk of an outbreak than intercity travel reductions, while intercity travel reductions can narrow the scope of the outbreak and help target resources. The timing, duration, and level of travel reduction together determine the impact of travel reductions on the number of infections, and multiple combinations of these can result in similar impact. Conclusions To prepare for the potential spread within Taiwan, we utilized Facebook’s aggregated and anonymized movement and colocation data to identify cities with higher risk of infection and regional importation. We developed an interactive application that allows users to vary inputs and assumptions and shows the spatial spread of the disease and the impact of intercity and intracity travel reduction under different initial conditions. Our results can be used readily if local transmission occurs in Taiwan after relaxation of border control, providing important insights into future disease surveillance and policies for travel restrictions.


2021 ◽  
Vol 2021 (1) ◽  
Author(s):  
Atena Ghasemabadi ◽  
Nahid Soltanian

AbstractThis paper presents a mathematical model that examines the impacts of traditional and modern educational programs. We calculate two reproduction numbers. By using the Chavez and Song theorem, we show that backward bifurcation occurs. In addition, we investigate the existence and local and global stability of boundary equilibria and coexistence equilibrium point and the global stability of the coexistence equilibrium point using compound matrices.


2020 ◽  
Vol 2020 (1) ◽  
Author(s):  
N. H. Sweilam ◽  
S. M. Al-Mekhlafi ◽  
A. O. Albalawi ◽  
D. Baleanu

Abstract In this paper, a novel coronavirus (2019-nCov) mathematical model with modified parameters is presented. This model consists of six nonlinear fractional order differential equations. Optimal control of the suggested model is the main objective of this work. Two control variables are presented in this model to minimize the population number of infected and asymptotically infected people. Necessary optimality conditions are derived. The Grünwald–Letnikov nonstandard weighted average finite difference method is constructed for simulating the proposed optimal control system. The stability of the proposed method is proved. In order to validate the theoretical results, numerical simulations and comparative studies are given.


Sign in / Sign up

Export Citation Format

Share Document