scholarly journals Focal Epithelial Hyperplasia

Viruses ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 1529
Author(s):  
Simone Kloch Bendtsen ◽  
Kathrine Kronberg Jakobsen ◽  
Amanda-Louise Fenger Carlander ◽  
Christian Grønhøj ◽  
Christian von Buchwald
Keyword(s):  
Clinical Presentation ◽  
Case Reports ◽  
Indigenous Populations ◽  
Epithelial Hyperplasia ◽  
Specific Primers ◽  
Hpv Genotypes ◽  
The World ◽  
First Time ◽  
Oral Condition ◽  
Focal Epithelial Hyperplasia

Focal epithelial hyperplasia (FEH) or Heck’s disease is a rare, benign, oral condition that is associated with infection by human papillomavirus type 13, 32 or both. The whiteish to mucosal-colored, soft, papular or nodular elevated lesions in the oral cavity are normally asymptomatic but can grow to a size or at a location where treatment is needed. The diagnosis is often based on clinical presentation and histopathology, and the HPV genotype can be determined using PCR utilizing specific primers or DNA sequencing. While FEH was reported to often affect several members of the same family and exist primarily among indigenous populations around the world, the number of reported cases within the European region is increasing. This contemporary review summarizes the main findings in relation to HPV genotypes, impact of superinfection exclusion and vaccination, transmission, diagnosis, geographical and ethnical distribution, comorbidities and treatment of FEH with an emphasis on including the most recent case reports within the field. Furthermore, we describe for the first time a FEH lesion infected with the low-risk HPV90.

scholarly journals Serious adverse reactions associated with ivermectin: A systematic pharmacovigilance study in sub-Saharan Africa and in the rest of the World

2021 ◽  
Vol 15 (4) ◽  
pp. e0009354
Author(s):  
Jérémy T. Campillo ◽  
Michel Boussinesq ◽  
Sébastien Bertout ◽  
Jean-Luc Faillie ◽  
Cédric B. Chesnais
Keyword(s):  
Drug Administration ◽  
Adverse Reactions ◽  
Case Reports ◽  
Individual Case ◽  
Sub Saharan Africa ◽  
World Health ◽  
The World ◽  
Excellent Safety Profile ◽  
Sub Saharan ◽  
First Time

Background Ivermectin is known to cause severe encephalopathies in subjects infected with loiasis, an endemic parasite in Sub-Saharan Africa (SSA). In addition, case reports have described ivermectin-related serious adverse drug reactions (sADRs) such as toxidermias, hepatic and renal disorders. The aim of this study was to identify suspected sADRs reported after ivermectin administration in VigiBase, the World Health Organization’s global individual case safety reports database and analyze their frequency relative to the frequency of these events after other antinematodal drugs reported in SSA and other areas of the world (ROW). Methods All antinematodal-related sADRs were extracted from VigiBase. Disproportionality analyses were conducted to investigate nervous, cutaneous, psychiatric, respiratory, renal, hepatic and cardiac suspected sADRs reported after ivermectin and benzimidazole drug administration across the world, in SSA and RoW. Principal findings 2041 post-ivermectin or post-benzimidazole suspected sADRs were identified including 667 after ivermectin exposure (208 in SSA and 459 in the RoW). We found an increased reporting for toxidermias, encephalopathies, confusional disorders after ivermectin compared to benzimidazole drug administration. Encephalopathies were not only reported from SSA but also from the RoW (adjusted reporting odds ratios [aROR] 6.30, 95% confidence interval: 2.68–14.8), highlighting the fact these types of sADR occur outside loiasis endemic regions. Conclusion We described for the first time suspected sADRs associated with ivermectin exposure according to geographical origin. While our results do not put in question ivermectin’s excellent safety profile, they show that as for all drugs, appropriate pharmacovigilance for adverse reactions is indicated.

Endemic human blastomycosis in Quebec, Canada, 1988–2011

2012 ◽  
Vol 141 (6) ◽  
pp. 1143-1147 ◽  
Author(s):  
I. V. LITVINOV ◽  
G. St-GERMAIN ◽  
R. PELLETIER ◽  
M. PARADIS ◽  
D. C. SHEPPARD
Keyword(s):  
Case Reports ◽  
Annual Incidence ◽  
Blastomyces Dermatitidis ◽  
Review Of Literature ◽  
Annual Incidence Rate ◽  
Endemic Region ◽  
Systemic Fungal Infection ◽  
The Past ◽  
The World ◽  
First Time

SUMMARYBlastomycosis is a systemic fungal infection found in various parts of the world. A review of literature for Quebec, Canada revealed only few case reports with the most recent one dating back to 1993. However, whether Quebec represents an important endemic region for blastomycosis in North America is unknown. In this work we reviewed 158 cases of human blastomycosis documented in Quebec during 1988–2011 using microbiological records available from the provincial public health laboratory. The estimated annual incidence of blastomycosis in the province is was ∼0·133 cases per 100 000 individuals with the highest rates of 0·79 and 0·46 cases per 100 000 recorded in South-eastern and South-western Quebec. Moreover, the annual incidence rate significantly increased over the past 20 years. This study for the first time establishes Quebec as an important endemic region for Blastomyces dermatitidis.

scholarly journals Variation in the clinical presentation of takotsubo cardiomyopathy in a non-referral hospital

2016 ◽  
Vol 5 ◽  
Author(s):  
Stefan Peters
Keyword(s):  
Takotsubo Cardiomyopathy ◽  
Clinical Presentation ◽  
Neurological Diseases ◽  
Case Reports ◽  
Referral Hospital ◽  
Cardiac Diseases ◽  
Clinical Presentations ◽  
Number Of Patients ◽  
The World ◽  
Varied Distribution

The spectrum of clinical presentations of takotsubo cardiomyopathy is larger than once suspected. There are several pulmonary and neurological diseases that can aggravate leading to atypical takotsubo cardiomyopathy documented in a large collective of case reports from all all over the world. This varied distribution of patients’ presentations is illustrated by several cases.  The spectrum of takotsubo cardiomyopathy can be enlarged in non-acute and non-cardiac diseases leading to an increase of this diagnosis in a large number of patients.

SEROPREVALENCE OF HIV AND HBsAg AMONGST BLOOD DONORS IN A TERTIARY CARE HOSPITAL, CHHATTISGARH.

2019 ◽  
Vol 3 (8) ◽  
Author(s):  
Anusha P ◽  
Bankar Nandkishor J ◽  
Karan Jain ◽  
Ramdas Brahmane ◽  
Dhrubha Hari Chandi
Keyword(s):  
Hepatitis B ◽  
Blood Donors ◽  
Hepatitis B Surface Antigen ◽  
Tertiary Care ◽  
Laboratory Diagnosis ◽  
Blood Bank ◽  
Care Hospital ◽  
Medical College ◽  
The World ◽  
First Time

INTRODUCTION: India being the second highly populated nation in the world. HIV/AIDS has acquired pandemic proportion in the world. Estimate by WHO for current infection rate in Asia. India has the third largest HIV epidemic in the world. HIV prevalence in the age group 15-49 yrs was an estimate of 0.2%. India has been classified as an intermediate in the Hepatitis B Virus (HBV) endemic (HBsAg carriage 2-7%) zone with the second largest global pool of chronic HBV infections. Safety assessment of the blood supply, the quality of screening measures and the risk of transfusion transmitted infectious diseases (TTIs) in any country can be estimated by scrutinizing the files of blood donors. After the introduction of the blood banks and improved storage facilities, it became more extensively used. Blood is one of the major sources of TTIs like hepatitis B, hepatitis C, HIV, syphilis, and many other blood borne diseases. Disclosure of these threats brought a dramatic change in attitude of physicians and patients about blood transfusion. The objective of this study is to determine the seroprevalence of transfusion transmitted infections amidst voluntary blood donors at a rural tertiary healthcare teaching hospital in Chhattisgarh. MATERIAL AND METHODS: This retrospective study was carried out in Chandulal Chandrakar Memorial Medical College, Kachandur, Durg. Blood donors were volunteers, or and commercial donors who donated the blood and paid by patients, their families, or friends to replace blood used or expected to be used for patients from the blood bank of the hospital. After proper donation of blood routine screening of blood was carried out according to standard protocol. Laboratory diagnosis of HIV 1 and HIV 2 was carried out by ELISA test. Hepatitis B surface antigen was screened by using ELISA. RESULTS: A total of 1915 consecutive blood donors’ sera were screened at Chandulal Chandrakar Memorial Medical College, blood bank during study period. Of these 1914 were male and 1 female. The mean age of patients was found to be 29.34 years with standard deviation (SD) of 11.65 Years. Among all blood donors in present study, 759(39.63%) were first time donors and 1156(60.37%) were repeated donors. 1 patient was HIV positive in first donation group while 3 (75%) were positive in repeat donation group. 7 (38.9%) were HBsAg positive in in first donation group while 11(61.1%) were positive in repeat donation group. Two patients in first donation group had dual infection of HIV and HBsAg. CONCLUSION: Seropositivity was high in repeated donors as compared to first time donors. The incidence of HIV is observed to be 0.2% and that of HBsAg is 0.94%. Strict selection of blood donors should be done to avoid transfusion-transmissible infections during the window period.

First report of Rinamba opacicollis Cameron (Hymenoptera: Braconidae, Doryctinae) in India as parasitoid of coffee stem borer, Xylotrechus quadripes (Chevrolat) (Coleoptera: Cerambycidae)

ENTOMON ◽  
2020 ◽  
Vol 44 (4) ◽  
pp. 311-314
Author(s):  
A. Roobakkumar ◽  
H.G. Seetharama ◽  
P. Krishna Reddy ◽  
M.S. Uma ◽  
A. P. Ranjith
Keyword(s):  
Integrated Control ◽  
Host Record ◽  
Stem Borer ◽  
Arabica Coffee ◽  
First Report ◽  
The World ◽  
First Time

Rinamba opacicollis Cameron (Hymenoptera: Braconidae) was collected from Chikkamagaluru, Karnataka, India for the first time from the larvae of white stem borer, Xylotrechus quadripes Chevrolat infesting arabica coffee. Its role in the biological or integrated control of X. quadripes remains to be evaluated. White stem borer could be the first host record of this parasitoid all over the world.

PERSPECTIVE DEVELOPMENT OF WORLD PRODUCTION OF FEEDS FOR AQUACULTURE: ALTERNATIVE SOURCES OF RAW MATERIALS

2017 ◽  
pp. 67-78
Author(s):  
Lina Yurievna Lagutkina
Keyword(s):  
Raw Materials ◽  
Limiting Factors ◽  
Current Status ◽  
Feed Production ◽  
The World ◽  
Market Trends ◽  
Alternative Sources ◽  
World Industry ◽  
First Time ◽  
A Current

The author of the article discloses the prospects of development of the world feed production for aquaculture based on the analysis of key innovative technological and market trends. The author specifies that shortage, high cost, low ecological compatibility of traditional raw materials - fish flour - are among major limiting factors in the development of production of feeds for aquaculture. This fact, in turn, limits sustainable development of aquaculture both in Russia, and in the world in general. The article presents the overview of a current status of the world industry of feed production in aquaculture, where the regional situation is studied, as well. For the first time, there is given the outlook of innovative technologies in feed production based on the alternative sources of protein (on the example of projects of leading aquabiotechnological companies) which will determine industry’s objectives for the mid-term perspective.

History Turmoil And Politico-Cultural Conditions of the Sub-Continental Men In Salman Rushdie’s Midnight’s Children

2015 ◽  
Vol 2 (2) ◽  
pp. 26-28
Author(s):  
Gunasekaran N ◽  
Bhuvaneshwari S
Keyword(s):  
Middle Class ◽  
Salman Rushdie ◽  
Fiction Writing ◽  
Pluralistic Society ◽  
Post Colonial ◽  
Cultural Conditions ◽  
The World ◽  
Midnight's Children ◽  
First Time

Salman Rushdie remains a major Indian writer in English. His birth coincides with the birth of a new modern nation on August 15, 1947. He has been justly labelled by the critics as a post-colonial writer who knows his trade well. His second novel Midnight’s Children was published in 1981 and it raised a storm in the hitherto middle class world of fiction writing both in English and in vernaculars. Rushdie for the first time burst into the world of fiction with subversive themes like impurity, illegitimacy, plurality and hybridity. He understands that a civilization called India may be profitably understood as a dream, a collage of many colours, a blending of cultures and nationalities, a pluralistic society and in no way unitary.

Histórias escritas com sangue: Uma análise de processos judiciários de assassinatos de mulheres em Goiânia (1970-1984)

2020 ◽  
Author(s):  
Neide Célia Ferreira Barros
Keyword(s):  
Power Relations ◽  
Case Reports ◽  
Border Region ◽  
Life And Death ◽  
Country Life ◽  
The World ◽  
Gender Power

This book analyzes the criminal processes of homicides or attempted homicides of women in Goiânia during the period of 1970-1984. We observed the gender power relations in the capital of Goiás, a border region, a mixture of country life elements and discourses of modernity. Hence, through case reports of women who suffered attacks on their lives in a period of intense changes, such as the organization of feminist groups in Brazil and the world, political and economic repercussions of the construction of Brasília in Goiás and mass immigration to Goiânia, we have pursued to understand what it meant socially to "be a man" and "to be a woman" in this capital and what consequences were brought into their bodies, concerning life and death, protection and punishment.

Sign in / Sign up

Export Citation Format

Share Document