scholarly journals Variation in the clinical presentation of takotsubo cardiomyopathy in a non-referral hospital

Author(s):  
Stefan Peters

The spectrum of clinical presentations of takotsubo cardiomyopathy is larger than once suspected. There are several pulmonary and neurological diseases that can aggravate leading to atypical takotsubo cardiomyopathy documented in a large collective of case reports from all all over the world. This varied distribution of patients’ presentations is illustrated by several cases.  The spectrum of takotsubo cardiomyopathy can be enlarged in non-acute and non-cardiac diseases leading to an increase of this diagnosis in a large number of patients.

2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Artur Q. B. da Silva ◽  
Taina V. de Sandes-Freitas ◽  
Juliana B. Mansur ◽  
Jose Osmar Medicina-Pestana ◽  
Gianna Mastroianni-Kirsztajn

There are scarce data about clinical presentation and outcomes of posttransplant membranous nephropathy (MN), and few reports include a large number of patients. This was a retrospective cohort including adult patients with posttransplant MN transplanted between 1983 and 2015 in a single center (n=41). Only patients with histological diagnosis of MN in kidney grafts were included. Clinical and laboratory presentation, histological findings, treatment, and outcomes were detailed. Patients were predominantly male (58.5%), with a mean age of 49.4 ± 13.2 years; 15 were considered as recurrent primary MN; 3 were class V lupus nephritis; 14 were considered as de novo cases, 7 secondary and 7 primary MN; and 9 cases were considered primary but it was not possible to distinguish between de novo MN and recurrence. Main clinical presentations were proteinuria (75.6%) and graft dysfunction (34.1%). Most patients with primary recurrent and de novo primary MN were submitted to changes in maintenance immunosuppressive regimen, but no standard strategy was identified; 31 patients presented partial or complete remission, and glomerulopathy appeared not to impact graft and patient survival.


2020 ◽  
Vol 5 (1) ◽  
pp. 61-67
Author(s):  
Sunnatullo Gafforov ◽  
◽  
Farkhod Khamroyev ◽  
Vazira Kuldasheva

We know that, currently in the world there is an increase in the number of patients, both children and adolescents, with psycho neurological diseases (PND). The authors, according to the results of the literature data studied over the last 10 years, argue that the problem associated with pathologies of the oral cavity organs in combination with PND is far from fully study. In their opinion, it is very important to study the relationship between these pathological processes and to develop therapeutic, diagnostic and preventive measures based on etiopatho genetic characteristics.


Author(s):  
Felix Awindaogo ◽  
Jane Afriyie-Mensah ◽  
Harold Ayetey ◽  
Emmanuella Tagoe

The clinical presentation of cardiac sarcoidosis is variable. We report two cases of cardiac sarcoidosis to highlight the varied clinical presentations and diagnostic challenges in our setting and encourage the consideration of sarcoidosis as a differential in unexplained arrhythmias and heart failure.


2018 ◽  
Vol 54 (6) ◽  
pp. 327-337 ◽  
Author(s):  
Andrea Dedeaux ◽  
Amy Grooters ◽  
Nobuko Wakamatsu-Utsuki ◽  
Joseph Taboada

ABSTRACT Opportunistic fungal infections have long been recognized as rare causes of disease in immunocompetent dogs and cats. Recently, the escalating use of multiagent immunosuppression protocols (especially those that include cyclosporine) has resulted in an increased number of patients with opportunistic fungal infection encountered by small animal practitioners and has altered the typical case phenotype. Based on histologic and cytologic features such as pigmentation, hyphal diameter, and distribution in tissue, these opportunistic mycoses can be placed into categories such as phaeohyphomycosis, hyalohyphomycosis, and eumycotic mycetoma. This review aims to summarize the clinical presentations, methods for diagnosis, treatment recommendations, and prognosis for both immunocompetent and immunosuppressed patients with opportunistic fungal infections. An example case description is included to illustrate the most common current clinical presentation.


Viruses ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 1529
Author(s):  
Simone Kloch Bendtsen ◽  
Kathrine Kronberg Jakobsen ◽  
Amanda-Louise Fenger Carlander ◽  
Christian Grønhøj ◽  
Christian von Buchwald

Focal epithelial hyperplasia (FEH) or Heck’s disease is a rare, benign, oral condition that is associated with infection by human papillomavirus type 13, 32 or both. The whiteish to mucosal-colored, soft, papular or nodular elevated lesions in the oral cavity are normally asymptomatic but can grow to a size or at a location where treatment is needed. The diagnosis is often based on clinical presentation and histopathology, and the HPV genotype can be determined using PCR utilizing specific primers or DNA sequencing. While FEH was reported to often affect several members of the same family and exist primarily among indigenous populations around the world, the number of reported cases within the European region is increasing. This contemporary review summarizes the main findings in relation to HPV genotypes, impact of superinfection exclusion and vaccination, transmission, diagnosis, geographical and ethnical distribution, comorbidities and treatment of FEH with an emphasis on including the most recent case reports within the field. Furthermore, we describe for the first time a FEH lesion infected with the low-risk HPV90.


2019 ◽  
Vol 7 (18) ◽  
pp. 3039-3042 ◽  
Author(s):  
Uwe Wollina ◽  
Claudia Krönert ◽  
André Koch ◽  
Jacqueline Schönlebe ◽  
Aleksandra Vojvodic ◽  
...  

BACKGROUND: Erythema elevatum diutinum (EED) belongs to the spectrum of cutaneous leukocytoclastic vasculitides. EED is a very rare dermatosis presenting with reddish to browning papules and plaques. EED may be associated with infections, hematologic and autoimmune disorders. CASE REPORTS: We present two patients with EED, a 50-year-old woman and a 42-year-old man. While the woman shows an association with colitis ulcerosa, the man had an anti-thrombin deficiency. Treatment was started with oral corticosteroid and dapsone, respectively. In both cases, there was a partial and temporary response. CONCLUSIONS: EED is a rare vasculitis with an unusual clinical presentation and a chronic course. Response to treatment is unsatisfactory and in the long-term run sometimes frustrating.


2021 ◽  
pp. 105566562110363
Author(s):  
Abiola Omodan ◽  
Pamela Pillay ◽  
Lelika Lazarus ◽  
Kapil Satyapal ◽  
Anil Madaree

Introduction The defects found in Tessier clefts number 3 and number 4 come in various forms in different patients. These variations have to a great extent affected not only documentation of these craniofacial defects but invariably their treatment and communication amongst craniofacial researchers. This study has not only documented the clinical presentation of these clefts in a South African population but has also incorporated the clinical presentation of Tessier clefts number 3 and 4 from different regions of the world. Methods The records of 8 patients, who had been treated for either Tessier clefts number 3 or 4, were reviewed and compared with 16 studies pulled from the literature systematically. The defects recorded as well as associated clefts and other congenital malformations were documented, and findings were compared. Results The anatomical and clinical presentation of the patients was compared to the reviewed literature and the different parameters were documented. In addition, associated clefts were also recorded in the study—it was noted that the association pattern recorded in Tessier cleft number 4 in this study did not conform to its traditional counterpart. Conclusion This study concluded that the clinical presentations of these clefts, however variable, seem to have a similar presentation worldwide. Additionally, associated clefts do not conform to the original Tessier classification system and therefore it is imperative for these patterns to be clearly mapped out.


2012 ◽  
Vol 50 (05) ◽  
Author(s):  
Z Visnyei ◽  
E Schafer ◽  
K Kardos ◽  
L Szentpétery ◽  
A Iványi ◽  
...  

1996 ◽  
Vol 35 (01) ◽  
pp. 41-51 ◽  
Author(s):  
F. Molino ◽  
D. Furia ◽  
F. Bar ◽  
S. Battista ◽  
N. Cappello ◽  
...  

AbstractThe study reported in this paper is aimed at evaluating the effectiveness of a knowledge-based expert system (ICTERUS) in diagnosing jaundiced patients, compared with a statistical system based on probabilistic concepts (TRIAL). The performances of both systems have been evaluated using the same set of data in the same number of patients. Both systems are spin-off products of the European project Euricterus, an EC-COMACBME Project designed to document the occurrence and diagnostic value of clinical findings in the clinical presentation of jaundice in Europe, and have been developed as decision-making tools for the identification of the cause of jaundice based only on clinical information and routine investigations. Two groups of jaundiced patients were studied, including 500 (retrospective sample) and 100 (prospective sample) subjects, respectively. All patients were independently submitted to both decision-support tools. The input of both systems was the data set agreed within the Euricterus Project. The performances of both systems were evaluated with respect to the reference diagnoses provided by experts on the basis of the full clinical documentation. Results indicate that both systems are clinically reliable, although the diagnostic prediction provided by the knowledge-based approach is slightly better.


2020 ◽  
Vol 1 (1) ◽  
pp. 55-57
Author(s):  
Dildora Khaydarova ◽  
◽  
Hilola Davronova ◽  
Asliddin Akbarov ◽  

Cerebrovascular diseases remain one of the most pressing medical and social problems in many countries of the world, due to their high prevalence, severity of complications and mortality. In Uzbekistan, the number of patients with cerebral stroke is quite large -about 40-45 thousandcases of cerebral stroke are registered annually


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