scholarly journals Excitement-Induced Cutaneous Bleeding (Haematidrosis-like) in a Dog

2021 ◽  
Vol 8 (12) ◽  
pp. 327
Author(s):  
Evi I. Sofou ◽  
Anna Gavra ◽  
Manolis N. Saridomichelakis
Keyword(s):  
Blood Count ◽  
Complete Blood Count ◽  
Reference Ranges ◽  
Intact Female ◽  
Patchy Distribution ◽  
Laboratory Findings ◽  
Term Evolution ◽  
The Face ◽  
Hair Shafts

A 15-month-old intact female Pitbull was referred because of recurrent, episodic, self-limiting, excitement-induced bleeding from nontraumatised skin. No abnormalities were detected upon physical examination. Subsequently, the dog went for a walk under the direct supervision of one of the authors, became overexcited and, after approximately five minutes, bloody liquid, with a patchy distribution, appeared along the hair shafts of the face and neck. The affected skin was congested, partially blanching on diascopy and bloody liquid was oozing from the follicular openings. Urticaria, dermographism and hypertension were excluded, the complete blood count and coagulation profile were within the reference ranges and an analysis of the bloody exudate confirmed its blood components. The cutaneous bleeding of the dog followed a self-limited course, with no episodes during the last two years. Clinical and laboratory findings and the long-term evolution of this dog bear striking similarities to haematidrosis, a rare human disease of multifactorial aetiology and equivocal pathogenesis.

Normal Reference Values of Complete Blood Count in Healthy Adult Population of Pakistan; A Multicentre Study

2021 ◽  
Vol 15 (11) ◽  
pp. 3040-3042
Author(s):  
Neelam Mazhar ◽  
Sarah Rafi ◽  
Saima Farhan ◽  
Shazia Yaseen ◽  
Nisar Ahmed
Keyword(s):  
Reference Values ◽  
Blood Count ◽  
Blood Donors ◽  
Complete Blood Count ◽  
Hematological Parameters ◽  
Adult Population ◽  
Armed Forces ◽  
Reference Ranges ◽  
Medical College ◽  
Normal Reference

Aim: To establish the reference values of hematological parameters in blood donors of all the four provinces of Pakistan as a general population. Methods: This was a multicenter cross-sectional study conducted from Jan 2017-Oct 2017 in the blood bank and the Dept. of Haematology, The CH&ICH, Lahore, Fatimid Foundation, Karachi, Bolan medical college, Quetta, Armed Forces Institute of Transfusion, Rawalpindi & Ayub medical college, Abbottabad, KPK. Blood samples of 1060 male and female blood donors were collected from the blood banks of all the centers mentioned above. CBC and differential were performed using an automated hematology analyzer in the respective departments. Results: The mean and 95% reference values (2.5th-97.5th) for males WBC 7.752+4.506×109 cells/L, RBC 4.958 +1.331, HB 14.258 +3.423 g/dl, HCT 41.967 +16.345, MCV 84.584 +15.933, PLT 219.485 +197.331, LYM 3.346 +10.112, NEUT 6.843+23.557, MONO 0.811 +3.601, EO 0.327 +0.995. For females WBC 7.174+3.037, RBC4.567 +1.086, HB 12.972 +2.752, HCT39.647 +48.186, PLT 264.07+175.079, LYM 2.537+5.005, NEUT 4.769+11.314, MONO 0.460 +0.909, EO 0.188+0.39 Conclusion: The hematological profile of the population in all four provinces of Pakistan differed from the reports of other countries and the standard reference ranges described in the textbook. So, our own hematological parameters must be followed. More studies must be carried out on other age groups and even on adults to strengthen our results. Keywords: Normal reference values, Complete blood count, Healthy adults of Pakistan

Recovery from Cyclophosphamide Overdose in a Dog

2017 ◽  
Vol 53 (4) ◽  
pp. 230-235 ◽  
Author(s):  
Jessica Renee Finlay ◽  
Kenneth Wyatt ◽  
Courtney North
Keyword(s):  
Blood Count ◽  
Complete Blood Count ◽  
Hemorrhagic Cystitis ◽  
Complete Recovery ◽  
Oral Cyclophosphamide ◽  
Granulocyte Colony Stimulating Factor ◽  
Heart Murmur ◽  
Stimulating Factor ◽  
Peripheral Neutrophil

ABSTRACT An adult female spayed dog was evaluated after inadvertently receiving a total dose of 1,750 mg oral cyclophosphamide, equivalent to 2,303 mg/m2, over 21 days (days −21 to 0). Nine days after the last dose of cyclophosphamide (day +9), the dog was evaluated at Perth Veterinary Specialists. Physical examination revealed mucosal pallor, a grade 2/6 systolic heart murmur, and severe hemorrhagic cystitis. Severe nonregenerative pancytopenia was detected on hematology. Broad spectrum antibiotics, two fresh whole blood transfusions, granulocyte colony stimulating factor, and tranexamic acid were administered. Five days after presentation (day +14), the peripheral neutrophil count had recovered, and by 12 days (day +21) the complete blood count was near normal. A second episode of thrombocytopenia (day +51) was managed with vincristine, prednisolone, and melatonin. The dog made a complete recovery with no long-term complications at the time of writing. To the author's knowledge, this is the highest inadvertently administered dose of cyclophosphamide to result in complete recovery.

scholarly journals Reference Ranges for Hematological Values in Umbilical Cord Blood in Pokhara, Nepal

2016 ◽  
Vol 36 (2) ◽  
pp. 160-164 ◽  
Author(s):  
Sahisnuta Basnet ◽  
Sandip Kumar Singh ◽  
Brijesh Sathian ◽  
Rajnish Mishra
Keyword(s):  
Blood Cell ◽  
Cord Blood ◽  
Cell Count ◽  
Umbilical Cord ◽  
Umbilical Cord Blood ◽  
Blood Count ◽  
Complete Blood Count ◽  
Reference Ranges ◽  
Blood Cell Count ◽  
Hematological Values

Correction: Due to an error in loading the metadata, the author Sahisnuta Basnet was omitted. Sahisnuta Basnet was therefore added to the metadata on 9th January 2017. The PDF was correct.Introduction: Reference hematological values in newborns are informative in evaluation of newborns to determine state of health or disease. For a given population, reference values may differ in accordance with various factors such as age, sex, race, diet, drug intake, altitude, socio-economic status and also the method employed for determination of the values. The aim of this study was to establish reference ranges of complete blood count using umbilical cord blood of normal, healthy, full term neonates born in Manipal Teaching Hospital (MTH), Pokhara, Nepal.Material and Method: The study was conducted in 210 full term, healthy newborns delivered in MTH between Jan 2014 to Feb 2015. Cord blood was collected and a complete blood count was obtained using an automated hematology analyzer.Result: Mean hemoglobin was 15.24 ± 1.96 gm/dl and mean red blood cell count was 4.30 ± 0.63 (range 3.05 – 6.36) X 1012/L. Mean white blood cell count was 14.93 ± 4.44 (range 6.10 ± 31.7) X 109/L and platelet count was 226.88 ± 61.28 (range 105 ± 392) X 109/L. There was no significant difference found in hemoglobin, red cell, white cell and platelet counts between males and females in this study.Conclusion: The values obtained from our study provide ranges for some hematological values in healthy newborns of Pokhara Nepal. However, the hematological reference values for Nepalese cord blood needs to be confirmed by larger numbers of samples from different centers of Nepal.J Nepal Paediatr Soc 2016;36(2):160-164.

Tunisian Newborn's Cord Blood: Reference Values of Complete Blood Count and Hemoglobin Fractions

2020 ◽  
Author(s):  
Sana Zitouni ◽  
Emna Bouatrous ◽  
Ons Laabidi ◽  
Imen Boudrigua ◽  
Dorra Chaouachi ◽  
...  
Keyword(s):  
Blood Cell ◽  
Cord Blood ◽  
Reference Values ◽  
Blood Count ◽  
Complete Blood Count ◽  
Hematological Parameters ◽  
Reference Ranges ◽  
Hematological Indices ◽  
Umbilical Blood ◽  
Vaginal Deliveries

Objective This study was aimed to establish local reference values for hematological indices and hemoglobin (Hb) fractions in umbilical cord blood (UCB) for the northern population of Tunisia. Study Design Our study included full-term newborns by vaginal deliveries. Hematological parameters were collected using an automated blood cell counter. The amounts of Hb fractions were measured by capillary electrophoresis of Hb. Statistical analysis was performed using R software. Results A total of 328 cord blood samples were analyzed. Among them, 154 (male: 44.8%, female: 55.2%) were used to establish reference values. The normal reference values of complete blood count (CBC) and Hb fractions were calculated. Mean neonatal Hb was 14.75 ± 2.26 g/dL. Gestational age affects the expression of CBC values as red blood cell (RBC), Hb, hematocrit (Hct), mean corpuscular volume (MCV), white blood cell (WBC), and the Hb profile. Umbilical blood hemogram parameters and Hb profile are affected by the environment; higher in newborns from urban regions but not affected by gender ratio. Conclusion Reference ranges of normal CBC indices and Hb fractions have been successfully established in Tunisian neonates' UCB. Our data suggest reference values that could be useful for neonatal patients' laboratory results and clinical interpretation. Key Points

scholarly journals Effect of First Long-Term Training on Whole Blood Count and Blood Clotting Parameters in Thoroughbreds

Animals ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 447
Author(s):  
Arianna Miglio ◽  
Emanuela Falcinelli ◽  
Anna Maria Mezzasoma ◽  
Katia Cappelli ◽  
Samanta Mecocci ◽  
...  
Keyword(s):  
Prothrombin Time ◽  
Blood Clotting ◽  
Blood Count ◽  
Complete Blood Count ◽  
Hematological Parameters ◽  
Training Period ◽  
Blood Collection ◽  
Negative Effects ◽  
Thoroughbred Racehorses

Training has a strong effect on the physiology of hematological parameters and blood coagulation, both in humans and in horses. Several blood changes have been reported after exercise in horses but available data differ. We aimed to investigate modifications in complete blood count and some hemostatic parameters induced by the first training period in young untrained Thoroughbred racehorses to detect a possible labile blood coagulability in racehorses. Twenty-nine untrained 2-year-old Thoroughbreds were followed during their incremental 4-month sprint exercise schedule. Blood collection was performed once a month, five times (T-30, T0, T30, T60 and T90), before and during the training period for measurement of complete blood count (CBC) and blood clotting parameters (prothrombin time—PT, activated partial prothrombin time—APTT, thrombin clotting time—TCT, fibrinogen—Fb, thrombin–antithrombin complex—TAT). Differences among the time points for each parameter were analyzed (ANOVA, Kruskal–Wallis one-way analysis of variance, p < 0.05). In Thoroughbreds, the first long-term exercise workout period was found to induce a statistical increase in red blood cell indexes and lymphocytes, eosinophils and platelet counts, as well as a hypercoagulability state evident at 30 days of training, which returned to basal levels after 90 days. Regular physical exercise seems to blunt the negative effects of acute efforts on hematological and clotting parameters, an effect that may be attributed to the training condition.

scholarly journals Is there Any Relationship Between Long-Term Mortality of Acute Pulmonary Embolism and Complete Blood Count Analysis?

2020 ◽  
Vol 12 (1) ◽  
pp. 44-49
Author(s):  
Fatma TOKGÖZ AKYIL ◽  
Gökhan SÖĞÜT ◽  
Murat Erdal OZANTÜRK ◽  
Ahmet TOPBAŞ ◽  
Hasan TÜTÜNCÜLER ◽  
...  
Keyword(s):  
Pulmonary Embolism ◽  
Blood Count ◽  
Acute Pulmonary Embolism ◽  
Complete Blood Count ◽  
Long Term Mortality

scholarly journals Comparative Analysis of Scheduling Algorithms Performance in a Long Term Evolution Network

2021 ◽  
Vol 3 (4) ◽  
Author(s):  
Bamidele Moses Kuboye
Keyword(s):  
Comparative Analysis ◽  
Packet Delay ◽  
Scheduling Algorithms ◽  
Long Term Evolution ◽  
Proportional Fair ◽  
Term Evolution ◽  
The Face ◽  
Resource Allocation Schemes ◽  
Long Term Evolution Network

The advancement in cellular communications has enhanced the special attention given to the study of resource allocation schemes. This study is to enhance communications to attain efficiency and thereby offers fairness to all users in the face of congestion experienced anytime a new product is rolled out. The comparative analysis was done on the performance of Enhanced Proportional Fair, Qos-Aware Proportional Fair and Logarithmic rule scheduling algorithms in Long Term Evolution in this work. These algorithms were simulated using LTE system toolbox in MATLAB and their performances were compared using Throughput, Packet delay and Packet Loss Ratio. The results showed Qos-Aware Proportional Fair has a better performance in all the metrics used for the evaluation.

Diagnostic and Prognostic Value of Routine Blood Tests in Patients with COVID-19 in Iran, Tehran

2021 ◽  
Author(s):  
Behzad Asanjarani ◽  
Goli Siri ◽  
Seyed Mahmoud Eshagh Hosseini ◽  
Hamed Abdollahi ◽  
Mehrdad Hasibi ◽  
...  
Keyword(s):  
Blood Count ◽  
Complete Blood Count ◽  
Adverse Outcomes ◽  
Control Group ◽  
Laboratory Findings ◽  
Distribution Width ◽  
Neutrophil Lymphocyte Ratio ◽  
Routine Blood ◽  
Novel Coronavirus ◽  
Comprehensive Metabolic Panel

Background: Routine blood testing consists of Complete Blood Count (CBC) indices together with Comprehensive Metabolic Panel (CMP) which have significant roles in both diagnosis and prognosis of the novel coronavirus disease 2019 (COVID-19). Methods: A total number of 942 COVID-19 patients and 400 healthy persons as the control group were enrolled in this study. All patients were admitted to a single center and were divided into two groups according to disease severity (severe or non-severe). Routine laboratory findings of peripheral blood sample were collected and then analyzed. Results: Neutrophil-Lymphocyte Ratio (NLR) had the highest sensitivity and specificity value for COVID-19 diagnosis. Among patients with different severities of COVID-19, the amount of neutrophil, NLR, platelet, hemoglobin, Red cell Distribution Width (RDW) and total bilirubin was significantly different (p<0.01). Conclusion: Some indices of complete blood count and comprehensive metabolic panel have diagnostic and prognostic roles in COVID-19 patients, which are helpful in early diagnosis, predicting severity and adverse outcomes of patients with COVID-19.

Retrospective Study on the Effects of Long-Term Use of Methylprednisolone Acetate on the Blood Work of 25 Cats

2019 ◽  
Vol 55 (1) ◽  
pp. 23-28
Author(s):  
Joanne Sohn ◽  
Theresa Gruber ◽  
Gaylord M. Brown
Keyword(s):  
Retrospective Study ◽  
Blood Count ◽  
Complete Blood Count ◽  
Reference Interval ◽  
Parenteral Administration ◽  
Methylprednisolone Acetate ◽  
Abnormal Laboratory ◽  
Laboratory Values

ABSTRACT Twenty-five cats at a private animal sanctuary received multiple nonimmunosuppressive doses of parenteral methylprednisolone acetate for at least 3 yr. Complete blood count, chemistry, and T4 results from these cats were examined to look for statistically significant changes. Results found significant changes in triglycerides, amylase, and monocytes. However, these changes remained within the reference interval. All other values showed no significant changes. These results suggest that after 3 yr of chronic parenteral administration of nonimmunosuppressive doses of methylprednisolone acetate, the complete blood count, chemistry, and T4 values in 25 cats were not significantly affected and did not result in abnormal laboratory values.

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