scholarly journals Maternal depression and non-specific health complaints in the offspring: a Danish cohort study

2020 ◽  
pp. bjgp20X714173
Author(s):  
Bente Kjær Lyngsøe ◽  
Dorte Rytter ◽  
Trine Munk-Olsen ◽  
Claus Vestergaard ◽  
Kaj Christensen ◽  
...  
Keyword(s):  
Maternal Depression ◽  
Post Treatment ◽  
Somatic Complaints ◽  
Health Complaints ◽  
Health Complaint ◽  
Time Treatment ◽  
Depressed Mothers ◽  
Prevalence Proportion ◽  
Self Assessed Health ◽  
First Time

Abstract Background: Maternal depression has been linked to adverse outcome in the offspring. Existing literature is mainly based on parental reports, which can be fallible when the parent suffers from depression. Aim: The aim of this study was to explore if maternal depression was associated with daily health complaints and low self-assessed health (SAH) in the offspring. Design and setting: Participants were 45,727 children from the Danish National Birth Cohort. Maternal depression was categorised into: no depression, first-time treatment, continued treatment, post treatment and relapse. Methods: Binomial regression was used to estimate the adjusted prevalence proportion ratio (aPPR) of frequent health complaints and low SAH in children of depressed mothers compared to children of non-depressed mothers. Results: The prevalence of any frequent health complaint was 10.8%, frequent somatic complaints was 3.2%, frequent mental complaints 8.7%, both frequent mental and somatic complaints 1.2%, and low SAH 5.3%. Children of mothers with depression (any category) were more likely to report a frequent health complaint; first-time treatment: aPPR=1.35 (95% CI: 0.96-1.85), continued treatment: aPPR=1.59 (1.37-1.85), post treatment: aPPR=1.30 (1.20-1.41), and relapse: aPPR=1.56 (1.35-1.79). Children of mothers with depression were also more likely to report low SAH; first-time treatment: aPPR=1.58 (0.99-2.54), continued treatment: aPPR=1.86 (1.51-2.28), post treatment: aPPR=1.34 (1.19-1.50), and relapse: aPPR=1.56 (1.26-1.93). Conclusions: Treatment of maternal depression was associated with higher prevalence of frequent health complaints and low SAH in the offspring at age 11 years. The association was strongest for children of mothers with continued depression or relapse.

scholarly journals The Role of School-Related Well-Being for Adolescent Subjective Health Complaints

2019 ◽  
Vol 16 (9) ◽  
pp. 1577 ◽  
Author(s):  
Tomas Vaičiūnas ◽  
Kastytis Šmigelskas
Keyword(s):  
Social Support ◽  
Well Being ◽  
Subjective Health ◽  
Population Based ◽  
Somatic Complaints ◽  
Health Complaints ◽  
Health Complaint ◽  
Subjective Health Complaints ◽  
Related Factors ◽  
Cross Sectional

Background: This study aimed to explore the prevalence of chronic specific-site and multisite pain in adolescents and to investigate how it can possibly be determined by school-related factors. Methods: A population-based cross-sectional study was conducted in 2014 in Lithuania as a Health Behavior in School-Aged Children (HBSC) survey. The sample consisted of 5730 school children, aged 11, 13, and 15 years. The analyzed data focused on the school-related context (relations with family, peers, and teachers; school demand, satisfaction, and bullying) of adolescents and subjective health complaints. The relationships between social support and health complaint variables were estimated using multivariate analyses. Results: The most common subjective health complaint among respondents was a headache. Backache, headache, and stomachache were more common among girls than boys. All somatic complaints were expressed more in younger ages. Multisite complaints were more common among girls and were associated with age—older ones reported more complaints. School-related bullying, school demand, satisfaction, and social support were the most relevant and independent factors for multisite somatic complaints among adolescents.

Maternal Depression: A Concern for Pediatricians

PEDIATRICS ◽  
1987 ◽  
Vol 79 (1) ◽  
pp. 110-117 ◽  
Author(s):  
Barry S. Zuckerman ◽  
William R. Beardslee
Keyword(s):  
Depressive Symptoms ◽  
Birth Weight ◽  
Maternal Depression ◽  
Adverse Outcomes ◽  
Somatic Complaints ◽  
Child Rearing ◽  
Special Role ◽  
Poor Growth ◽  
Depressed Mothers ◽  
Poor Outcomes

Maternal depression is common in clinical experience but has not been fully addressed in the pediatric literature. Depression can refer to either depressive symptoms or a diagnosable depression. Depression among mothers occurs frequently, is persistent, and is related to other factors such as low social class and marital disharmony. Studies demonstrate an association between a mother's depression and adverse outcomes for her child including low birth weight, behavior problems, somatic complaints, poor growth, accidents, and affective illness. Affect and child-rearing characteristics of depressed mothers seem to be important factors in mediating these poor outcomes. Pediatricians have a special role in helping depressed mothers and their children.

scholarly journals Evaluation of anthocyanin encapsulation efficiency into yeast cell by plasmolysis, ethanol, and ultrasound treatments using alone or in combination

Food Research ◽  
2019 ◽  
Vol 4 (2) ◽  
pp. 557-562
Author(s):  
M.D. Lieu ◽  
T.T.H. Hoang ◽  
H.N.T. Nguyen ◽  
T.K.T. Dang
Keyword(s):  
Yeast Cell ◽  
Encapsulation Efficiency ◽  
Color Stability ◽  
Water Soluble ◽  
Impact Factors ◽  
Time Treatment ◽  
Treated Sample ◽  
Potential Applications ◽  
The Individual ◽  
First Time

Anthocyanin is a water-soluble color compound of the flavonoid which was successfully encapsulation in Saccharomyces cerevisiae by plasmolysis, ethanol, and ultrasound treatments using alone or in combination in the first time. Treatment agents significantly enhanced the encapsulation efficiency of anthocyanin fluid. The encapsulation yield (EY) of the combined factors was higher than the individual impact factors. Ethanol 10% (v/v) and ultrasound 180 seconds for the highest EY 40.22±0.67%, then ethanol 10% (v/v) and NaCl 10% (w/v) for EY 36.45±0.35%, NaCl 10% and ultrasound for EY 32.14±0.98% lowest. The color stability evaluation of the capsules was carried out at 80°C for 30 minutes. The color lost rate was determined by the spectrometer. The color loss of samples with the un-treatment yeast was 20.45±1.21%, higher than the treated sample. This suggests that anthocyanin encapsulation by yeast cell is efficient in overcoming the effects of high temperatures and having potential applications in food processing.

Maternal depressive disorder and contextual risk: Contributions to the development of attachment insecurity and behavior problems in toddlerhood

1998 ◽  
Vol 10 (2) ◽  
pp. 283-300 ◽  
Author(s):  
DANTE CICCHETTI ◽  
FRED A. ROGOSCH ◽  
SHEREE L. TOTH
Keyword(s):  
Behavior Problems ◽  
Maternal Depression ◽  
Child Behavior ◽  
Child Behavior Problems ◽  
Contextual Risk ◽  
Number Of Children ◽  
Increased Risk ◽  
Report Data ◽  
Depressed Mothers ◽  
And Behavior

Research has shown that offspring of depressed caregivers are at increased risk for maladaptive development and emotional difficulties. Specifically, infants and toddlers of depressed mothers have been shown to evidence higher percentages of insecure attachments and more behavioral difficulties than offspring of nondisordered mothers. However, even in studies that reveal significant differences between children of depressed and nondepressed caregivers, a substantial number of children with depressed caregivers do not evidence dysfunction. Such findings have resulted in increased attention to the broader social context in which children of depressed mothers develop. This investigation examined the direct influences of maternal depression on child development, as well as the role of contextual risks that may be particularly heightened in families with depressed parents. Toddlers with depressed mothers evidenced significantly more insecure attachments than did toddlers with nondisordered mothers, and this difference was not accounted for by contextual risk. In predicting child behavior problems, contextual risk was found to mediate the relation between maternal depression and child behavior problems. Father-report data on child behavior corroborated the mother report data. Results are discussed in terms of the diversity of functioning in offspring of depressed caregivers that can be attributed to varied levels of contextual risk accompanying depression.

scholarly journals PET Imaging of CD8 via SMART for Monitoring the Immunotherapy Response

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Lingyi Sun ◽  
Zhonghan Li ◽  
Yongyong Ma ◽  
Johannes Ludwig ◽  
Hyun S. Kim ◽  
...  
Keyword(s):  
Pet Imaging ◽  
Positive Response ◽  
Imaging Study ◽  
Inadequate Response ◽  
Time Treatment ◽  
Promising Strategy ◽  
Positron Emission ◽  
First Time ◽  
Ct26 Tumor ◽  
Selection Of

Imaging of CD8 receptors on T-cells by positron emission tomography (PET) has been considered a promising strategy for monitoring the treatment response to immunotherapy. In this study, a trial of imaging CD8 with our newly developed sequential multiple-agent receptor targeting (SMART) technology was conducted. Mice bearing a subcutaneous colorectal CT26 tumor received three times different immunotherapy treatments (PD1 or CTLA4 or combined). On either day 7 or day 14 after the first time treatment, the PET imaging study was performed with sequentially administered TCO-modified anti-CD8 antibody and 64Cu-labeled MeTz-NOTA-RGD. However, no positive response was detected, probably due to (1) inappropriate selection of biomarkers for the SMART strategy, (2) limited TCO modification on the anti-CD8 antibody, and (3) inadequate response of the CT26 tumor to the selected immunotherapies. Therefore, the potential of applying SMART in imaging CD8 was not demonstrated in this study, and further optimization will be necessary before it can be applied in imaging CD8.

scholarly journals Family life stress, maternal depression and child behavioral health in industrialized Italian cities

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
E Bansal ◽  
S Renzetti ◽  
N Xhani ◽  
G Cagna ◽  
M Conversano ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Maternal Depression ◽  
Behavioral Health ◽  
Family Life ◽  
Internalizing Problems ◽  
Life Stress ◽  
Externalizing Problems ◽  
Maternal Depressive Symptoms ◽  
Italian Version ◽  
Depressed Mothers

Abstract Although family life stress adversely impacts child health, few tools measure its relationship to child outcomes in the setting of maternal variables. This study validates the Italian version of Crisis in Family Systems-Revised (CRISYS-R) and characterizes relationships between family life stress, maternal depression and child behavior in two Italian cities. This cross-sectional study was nested in current research on health impacts of neurotoxic environmental exposures in children. 101 mother-child pairs (child age=9.91±2.17yrs; 53% female) and children's teachers were enrolled in Taranto (south Italy) and Brescia (north Italy). Mothers performed the Italian CRISYS-R and PHQ9; teachers completed Child Behavior Checklist (CBCL/6-18). Spearman's rank correlation coefficients showed associations of family CRISYS-R, maternal PHQ9 and child CBCL/6-18. Wilcoxon Rank-Sum test compared groups of continuous variables. Mothers with depressive symptoms (PHQ9≥5) reported higher ongoing stress and proportion of negative stressors on CRISYS-R than non-depressed mothers (p < 0.05). Children of depressed mothers performed worse in all CBCL/6-18 domains: Internalizing Problems, Externalizing Problems and Total Problems (p < 0.01). Specifically, children of depressed mothers scored higher on subscales of Anxious-Depressed (p < 0.05), Withdrawn-Depressed (p < 0.01), Rule-Breaking (p < 0.01) and Aggressive Behavior (p < 0.05). Maternal depressive symptoms correlated with ongoing stress (rs = 0.27; p < 0.01), child Internalizing Problems (rs = 0.34; p < 0.001), Externalizing Problems (rs = 0.28; p < 0.01) and Total Problems (rs = 0.35; p < 0.001). This study describes links among maternal depression, family life stress, and child behavioral health. It is first to validate Italian CRISYS-R and to explore these factors conjointly in Italian contexts with known neurotoxic exposures. Findings support considering maternal depression and family life stress in child behavioral and environmental health research and policy. Key messages Family life stress, maternal depressive symptoms, and preadolescent behavioral health were highly interrelated in two industrialized Italian cities. The Italian version of CRISYS-R is a useful instrument for assessing and understanding family life stress, a crucial yet under-explored contributor to child behavioral health outcomes.

Social workers first-time treatment assessment.

2018 ◽  
Vol 36 (30_suppl) ◽  
pp. 164-164
Author(s):  
Christa Poole ◽  
Tori Nelson ◽  
Jacqueline Barnes ◽  
Angela Clay ◽  
Erica Coyle ◽  
...  
Keyword(s):  
Problem Solving ◽  
Social Workers ◽  
Data Analytics ◽  
Clinical Care ◽  
Well Being ◽  
Chemotherapy Treatment ◽  
Treatment Assessment ◽  
Time Treatment ◽  
Patient Assessments ◽  
First Time

164 Background: Supporting emotional, psychological, financial and spiritual well-being of patients has been shown to have a positive impact on quality of life and patient experience. Social workers in our outpatient cancer center are responsible for completing new patient assessments at the start of chemotherapy treatment to provide early access to psychosocial support services. Assessments are to be completed within three weeks of the patient’s first chemotherapy treatment. Connecting with patients early in the care experience allows social workers to proactively assist with education, support and link patients to vital resources. Methods: Completed assessments were tracked and from October through December 2017. The social workers leveraged the use of data analytics and a team based approach to increase the number of new patient assessments completed within the first 3 weeks of chemotherapy. Weekly 30-minute huddles were held using problem solving methods, including brain storming, cause and effect diagrams, force ranking, and polling. Results: A team identified 39 potential causes to why 65.14% of patients were not receiving assessments within the first 3 weeks of chemotherapy treatment. Potential causes were grouped and themed. Work prioritization, inconsistent methods of identifying patients receiving chemotherapy for the first time, and lack of visual management to monitor progress of this metric were identified as key objectives for improvement. Countermeasures were developed and implemented; a dashboard was created to analyze the first time treatment assessment completion percentages by disease group and standardizing the process of notifying social workers of patients in need of an assessment. Social worker assessment completion rates improved from 34.78% (December 2017) to 75.35% (April 2018). Conclusions: This project demonstrates the value of utilizing problem solving, visual management, and data analytics for continuous quality improvement projects related to clinical care and processes. Cross-disciplinary collaboration should be explored with the use of visual tools and other resources to facilitate communication that is understood by all disciplines.

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