A STUDY ON THE CLINICAL AND SUB-CLINICAL FEATURES OF BACTERIAL SKIN INFECTIONS

2020 ◽  
pp. 56-61
Author(s):  
Anh Mai Ba Hoang ◽  
Phuong Nguyen Thi Thanh ◽  
My Nguyen Thi Tra ◽  
Nguyen Le Thi Cao ◽  
Nam Tran Ngoc Khanh

Background: Bacterial skin infections are common due to the bacteral invasion into the skin and cause a variety of clinical manifestation. In order to assess the characteristics of this group, we conducted this study to evaluate the clinical and main subclinical features. Methods: A total of 95 patients were diagnosed with bacterial skin infections at Dermatology Clinic of Hue University of Medicine and Pharmacy Hospital from June 2015 to May 2016, of which 34 patients had some tests and 19 patients had samples for culture. Results: The age group of 16 - 30 years old was the most popular: 50.5%; High rate of patients came for consultation in winter (49.5%), most patients had no fever. For functional symptoms, pain accounted for the highest proportion: 71.6%. The most common skin lesion was nodule: 38.8%, the lower extremities were the most common position: 38.9%. Furuncle had the highest incidence: 45.3%. For main laboratory tests, most patients had a normal number of leucocyte: 71.4%; ESR increased by two times accounting for a rate of 20.6%; culture results showed Staphylococcus aureus being a highest percentage: 57.9%. Conclusion: Most skin infections localized and were less systemic effect, the most common agent was S. aureus. Keywords: infection, bacteria, skin, fever, S. aureus

2019 ◽  
Vol 12 (8) ◽  
pp. 454-458 ◽  
Author(s):  
David Gleeson

Every year, around 24% of the population consults their GP about a skin problem. Bacterial skin infections, especially in the paediatric and elderly populations, are common and some are potentially life-threatening. The most common bacterial pathogens associated with skin infections are Staphylococcus aureus and Staphylococcus pyogenes. This article will cover diagnosis and management of the most common skin infections, high-lighting important features of potentially lethal presentations requiring hospitalisation. Infections affecting superficial layers of the skin, deeper layers, and accessory tissues are considered.


2016 ◽  
pp. 132-136
Author(s):  
Trung Thuan Phan ◽  
Dinh Binh Tran ◽  
Thanh Hue Dinh ◽  
Phong Son Dinh

Objective: Infection genital under tract are an important problem of reproductive health care in the community, especially by living habits, personal hygiene and other environmental. Therefore, the perception of Infection genital under tract in Khmer women is poor, the level of knowledge and education is not high, psychological examines gynaecology or sometimes didn't interested to gynecological inflammation. Methods: Cross-sectional study of 830 Khmer women in Can Tho city. Results: (1) The rate of Infection genital tract under is 42.3%, Cervicitis accounts for 43.0%, followed by 24.5% of vaginitis; inflammation of the vulva 1.4%, combine of three lesion is 6.3%; (2) A high rate of Infection genital tract under in ≤ 20 age group accounts for 57.1%.(3) A high rate of Infection genital tract under is the farming industry groups (accounting for 75.8%). Conclusion: (1) Cervicitis accounts for the highest proportion. (2) Infection genital tract under in ≤ 20 age group for the highest proportion, descending to ≥ 41 age group. (3) The high proportion of Infection genital tract under relates to age group, occupation, place of living. KEYWORDS: Infection genital tract under, Khmer women, Can Tho city...


2021 ◽  
Vol 49 (1) ◽  
Author(s):  
Jane Namukobe ◽  
Peter Sekandi ◽  
Robert Byamukama ◽  
Moses Murungi ◽  
Jennifer Nambooze ◽  
...  

Abstract Background Rural populations in Uganda rely heavily on medicinal plants for the treatment of bacterial skin infections. However, the efficacy of these medicinal plants for their pharmacological action is not known. The study aimed at evaluating the antibacterial, antioxidant, and sun protection potential of Spermacoce princeae, Psorospermum febrifugum, Plectranthus caespitosus, and Erlangea tomentosa extracts. Methods The plant samples were extracted by maceration sequentially using hexane, dichloromethane, ethyl acetate, methanol, and distilled water. Antibacterial activity of each extract was carried out using an agar well diffusion assay against Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli, Klebsiella pneumonie, Streptococcus pyogenes, and Salmonella typhi. Acute dermal toxicity of the aqueous extract of S. princeae and P. febrifugum, and E. tomentosa was assessed in young adult healthy Wistar albino rats at a dose of 8000 and 10,000 mg/kg body weight. The antioxidant activity of each extract was carried out using a 1,1-diphenyl-2-picryl-hydrazyl (DPPH) radical scavenging assay. The sun protection factor was determined using Shimadzu UltraViolet-Visible double beam spectrophotometer between 290 and 320 nm. Results The plant extracts showed good antibacterial activity against the tested bacterial strains with minimum inhibitory concentration (MIC) ranging between 3.12 and 12.5 mg/ml. There was no significant change in the levels of creatinine, alanine aminotransferase, and aspartate aminotransferase in the rats even at a higher dose of 10,000 mg/kg, which was related to the results of biochemical analysis of the blood samples from the treated and control groups. The aqueous and methanol extracts of S. princeae showed potential antioxidant properties, with half maximal inhibitory concentration (IC50) values of 59.82 and 61.20 μg/ml respectively. The organic and aqueous extracts of P. caespitosus showed high levels of protection against Ultraviolet light with sun protection potential values ranging between 30.67 and 37.84. Conclusions The study demonstrated that the selected medicinal plants possessed good antibacterial, antioxidant, and sun protection properties. Therefore, the plants are alternative sources of antibacterial, antioxidant, and sun protection agents in managing bacterial skin infections.


2015 ◽  
Vol 42 (4) ◽  
pp. 485-499 ◽  
Author(s):  
Fadi Ibrahim ◽  
Tariq Khan ◽  
George G.A. Pujalte

Author(s):  
Ashok Garg ◽  
Ashish Sharma ◽  
Sandhya Kumari ◽  
Ambuj Shandil

Background: Meningitis is one of the fatal infections occurring in infants and older children. In acute bacterial meningitis (ABM), inflammation of the leptomeninges is triggered by bacteria present in the subarachnoid space. ABM is associated with a high rate of acute complications and long-term morbidity. Aim of our study was to determine the incidence, etiological profile and complications of acute bacterial meningitis amongst children belonging to one month to five years of age.Methods: The present study was conducted over a period of one year and diagnosis of meningitis was made on basis of history, examination and laboratory investigations. Clinical features were recorded on case sheet. Lumbar puncture was done, and CSF was sent for biochemical analysis, cell counts, staining, culture and latex agglutination test (LAT).Results: Out of total 1560 admitted cases (1 month to 5years age group), 160 cases were suspected with meningitis while 57 cases were confirmed to have ABM. Most (59.6%) cases belonged to 3 months to 1-year age group and males outnumbered the females by a ratio of 2:1. Group B Streptococcus (45.6%) was most common pathogen in 45.6% cases followed by Streptococcus pneumoniae (21%) and Hemophilus influenzae (10.52%). Seizures (45%) and increased ICP (28%) were main acute complications observed during hospitalization while hemiparesis 9.6%, monoparesis 4.8%, seizures 38%, vision and hearing deficits were the sequelae observed on follow up examination. These complications were predominantly contributed by S. pneumoniae and H. Influenzae.Conclusions: The incidence of ABM is still high and Group B streptococcus is main pathogen even in post neonatal period. The complications of ABM are markedly higher in cases of S. pneumoniae, H. Influenzae meningitis in comparison to Group B streptococcus meningitis. Formulating standard protocols for management of ABM and rational antibiotic use to prevent resistance is the need of hour.


Author(s):  
Hariprasad S. ◽  
Teerthanath Srinivas

Background: Groin hernia is a very common type abdominal wall hernia encountered in surgical practice. Irreducibility, obstruction and strangulation are its commonest complications which usually presents as acute emergencies. Emergency repair of complicated hernias is associated with poor prognosis and a high rate of post-operative complications even with better care, improved anaesthetic management and advanced surgical techniques. The aim of this study was to determine the various modes of presentation, clinical finding, diagnostic and therapeutic strategies and to evaluate the postoperative outcome in complicated groin hernia surgeries in our set up.Methods: The study was carried out among 40 patients of groin hernia, who had complicated clinical presentation like irreducibility, strangulation and obstruction in the department of general surgery, during the period from March 2012 to June 2014. Patients were enrolled into the study after proper consent for detailed clinical examination, investigation and subsequent treatment. The Data obtained included demographic characteristics, presentation, operative findings and outcome. The patients were followed up for immediate and late complications for once a week for 1 months, once every month for the next 6 months. After data collection, analysis was done with help of by SPSS software version 21.Results: A total of 40 groin hernia patients with complicated presentation were evaluated during the study period. Among these cases 38 cases had inguinal hernias and two cases had femoral hernia. Majority of the patients were in 5th and 6th decade. Complicated presentation of groin hernia was commonly seen in males (95%) than in females (5%) with male to female ratio of 19:1. Inguinal hernia complications were seen predominantly in males and femoral hernia complications in females. Right sided hernias were more common. Incarceration was the commonest complication seen in 70% of case followed by strangulation (30%). Incarceration was high (17.5%) in the age group of 64-73 years and 44 - 53 years. Strangulation was high in the age group of 54-63 years. The duration of hernia varied for 1-2 years in 42.5% of cases and 3-6 years in 27.5% of cases. Majority of the patients (30%) presented with localized groin pain, vomiting, constipation and abdominal distension. All patients presented with swelling in the inguinoscrotal region, which was tender, and there was no impulse on coughing and 35% of patients had cardiorespiratory illness. Majority of the cases (34 numbers) were operated as emergency procedure. Viable bowel was seen in 77.5% of cases. Bowel resection and end-to-end anastomosis was done in all cases of non-viable bowel and orchidectomy in atrophied and gangrenous testis. The commonest postoperative complication encountered in the study was wound infection (22.5%) and scrotal seroma (17.50%). There was no evidence of recurrence in any of the operated cases.Conclusions: Complicated presentations of groin hernias like, incarceration and strangulation are seen in low and middle socio-economic category of people and may be associated with chronic illness. The cumulative risk of strangulation increases with time and type of hernias. Timely diagnosis and prompted surgical repair is essential to prevent the complications. 


Author(s):  
M. Nandini ◽  
S. B. Kiran Madhusudhan

The study group consisted of 150 patients both male and female between 1 – 80 years, with primary and secondary skin infections who attended the out- patient department of Dermatology and surgery at Sree Balaji medical college and hospital a tertiary care hospital in Chennai, Tamilnadu, South India. Patients admitted as in patients in the above two department were also taken for this study. 28 out of 150 cases had primary bacterial and 122 had secondary bacterial skin infections. In this study the prevalence of Methicillin resistant Staphylococcus aureus (MRSA) (40.8%) and Extended spectrum beta-lactamases (ESBL) (40.5%) producers among Enterobacteriaceae was higher. Estimation of MRSA and ESBL has to be done in tertiary care hospital to prevent and curtail further spread of these strains in hospital acquired infections. These isolates pose a serious threat for use of routine groups of antimicrobials.


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