The Challenges of the Elderly Population with Alzheimer’s and Dementia in Honduras

2019 ◽  
pp. 39-43
Author(s):  
Orlando Rivero, DBA
Keyword(s):  
Public Health ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Rural Areas ◽  
Elderly Population ◽  
Total Population ◽  
The Elderly ◽  
Healthcare Services ◽  
Health Policies ◽  
Public Health Policies

The purpose of this paper is to analyze the number of Alzheimer’s and Dementia incidences occurring in Honduras and afford recommendations to improve public health policies to assist the elderly. According to The Institute for Health Metrics and Evaluation (2016), there has been an increase in the number of Alzheimer’s incidences in Honduras. Moreover, the numberof Alzheimer’s cases has increased by 51.4% from 2005-2016. The findings suggested that the country needs to consider a reevaluation of public health policies to tackle the influx of Alzheimer’s incidences in the upcoming years. Though the elderly population stands at a little less than 6% of Honduras; total population (Bermúdez-Madriz et al., 2011), it is critical that the elderly community be afforded the best possible healthcare services available. Research suggests that most of the elderly community reside in rural areas where minimal healthcare services are available. In the end, the recommendations will be afforded for the improvement of public health policies to assist the elderly and preparedness for the surge of Alzheimer’s disease in the country.

scholarly journals Need for public health policies in the elderly population: indicators of aging in a Social Security Institute in Mexico

2019 ◽  
Vol 155 (91) ◽  
Author(s):  
Daniel López-Hernández ◽  
Nadhyieli Orozco-Campos ◽  
Irma Luz Riva Palacio Chiang y Sam ◽  
Margarita Blanco-Cornejo
Keyword(s):  
Public Health ◽  
Social Security ◽  
Elderly Population ◽  
The Elderly ◽  
Health Policies ◽  
Public Health Policies ◽  
Social Security Institute

scholarly journals APOE-ε4 polymorphism and cognitive deficit among the elderly population of Fernando de Noronha

2008 ◽  
Vol 66 (2b) ◽  
pp. 298-302 ◽  
Author(s):  
Anália Nusya Garcia ◽  
Helker Albuquerque da Silva ◽  
Renan Carlos Silva ◽  
Eliane Maria Medeiros Leal ◽  
Lorena Rodrigues ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Elderly Population ◽  
Cognitive Deficit ◽  
The Elderly ◽  
Clock Drawing Test ◽  
Apoe Ε4 ◽  
Pcr Rflp ◽  
Fernando De Noronha ◽  
Ε4 Allele

BACKGROUND: Polymorphism of the gene for apolipoprotein E (APOE) is an important risk factor for the development of Alzheimer's disease. The ε4 allele of the APOE gene has been linked with a number of neuropsychiatric illnesses, and also with stress and depression among geriatric populations. OBJECTIVE: To identify APOE-ε4 polymorphism and correlate this with cognitive deficit among the elderly population of the island of Fernando de Noronha. METHOD: Neuropsychiatric tests (mini-mental state examination, verbal fluency test and clock drawing test) were applied to 52 elderly people without Alzheimer's disease. DNA was isolated from peripheral blood and genotyping of APOE was done by the PCR-RFLP method. RESULTS: 87% of the elderly population (mean age 69.6±7.0) had cognitive deficit. CONCLUSION: The observed frequency of the ε4 allele was 10%, but the correlation between the presence of ε4 and cognitive deficit in this population was not statistically significant.

scholarly journals The Prevalence of Alzheimer’s Disease; its Risk and Protective Factors Among the Elderly Population in Iran

2017 ◽  
Vol 18 (9) ◽  
Author(s):  
Sakineh Gholamzadeh ◽  
Banafsheh Heshmati ◽  
Arash Mani ◽  
Peyman Petramfar ◽  
Zahra Baghery
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Protective Factors ◽  
Elderly Population ◽  
The Elderly ◽  
Risk And Protective Factors

Metabolomic Alterations in the Blood and Brain in Association with Alzheimer’s Disease: Evidence from in vivo to Clinical Studies

2021 ◽  
pp. 1-28
Author(s):  
Sirawit Sriwichaiin ◽  
Nipon Chattipakorn ◽  
Siriporn C. Chattipakorn
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Clinical Studies ◽  
Elderly Population ◽  
The Elderly ◽  
Pathological Findings ◽  
Major Health Problem ◽  
Major Health ◽  
The Brain

Alzheimer’s disease (AD) has become a major health problem among the elderly population. Some evidence suggests that metabolic disturbance possibly plays a role in the pathophysiology of AD. Currently, the study of metabolomics has been used to explore changes in multiple metabolites in several diseases, including AD. Thus, the metabolomics research in AD might provide some information regarding metabolic dysregulations, and their possible associated pathophysiology. This review summarizes the information discovered regarding the metabolites in the brain and the blood from the metabolomics research of AD from both animal and clinical studies. Additionally, the correlation between the changes in metabolites and outcomes, such as pathological findings in the brain and cognitive impairment are discussed. We also deliberate on the findings of cohort studies, demonstrating the alterations in metabolites before changes of cognitive function. All of these findings can be used to inform the potential identity of specific metabolites as possible biomarkers for AD.

Análise das políticas públicas de saúde do idoso: estudo de revisão de literatura

2009 ◽  
Vol 3 (2) ◽  
pp. 317
Author(s):  
Alessandra Conceição Leite Funchal Camacho ◽  
Maria José Coelho
Keyword(s):  
Public Health ◽  
Public Policies ◽  
The Elderly ◽  
Health Policies ◽  
Review Of Literature ◽  
Publication Type ◽  
Public Health Policies ◽  
The Public ◽  
Knowledge Database ◽  
Revisión Sistemática

ABSTRACTObjective: to examine the public health policies of the elderly in the references of the main databases from 2004 to 2008. Method: study of systematic review of literature conducted on databases of the Library of Health, in September 2008. For information analysis was organized the content found on the year, publication type and methods/techniques, content and essence of the production of knowledge, database, the authors' recommendations. Results: the references that were analyzed 26 and 10 in the database SCIELO, one in the BDENF and 15 in the LILACS. Conclusion: we observed an increase in publications dealing with professionals in health operationalized the public health policies of the elderly as the main recommendations bringing the development of public policies that take into account the specifics of the elderly, facilitating their access and that could reduce inequality. Mention the importance of visibility of the aging process and adequacy of public policies aimed at expansion of the strategies that have the caregiver as the leading subject. Descriptors: health public policy; aged; nursing.RESUMOObjetivo: analisar as políticas públicas de saúde do idoso nas referências das principais bases de dados de 2004 a 2008. Método: estudo de revisão de literatura sistemática realizada nas bases de dados da Biblioteca Virtual da Saúde, em setembro de 2008. Para análise das informações foi realizada a organização do conteúdo encontrado quanto ao ano, tipo de publicação e métodos/técnicas, essência do conteúdo e produção do conhecimento, base de dados, recomendações dos autores. Resultados: as referências analisadas foram 26 sendo 10 na base de dados SCIELO, uma na BDENF e 15 na LILACS. Conclusão: Verificamos um aumento de publicações que tratam de profissionais na área da saúde operacionalizando as políticas públicas de saúde do idoso trazendo como principais recomendações o desenvolvimento de políticas públicas que levem em conta as especificidades do idoso, facilitando o seu acesso e que possam reduzir desigualdades. Referem a relevância da visibilidade do processo de envelhecimento e adequação das políticas públicas visando à ampliação de estratégias que tenham o cuidador como sujeito principal. Descritores: políticas públicas de saúde; idoso; enfermagem.RESUMENObjetivo: analizar las políticas de salud pública a los ancianos en las referencias de las principales bases de datos de 2004 a 2008. Método: estudio de revisión sistemática de literatura sobre las bases de datos de la Biblioteca de la Salud, en setiembre de 2008. Resultados: las referencias que se analizaron fueron 26, tenendo 10 en la base de datos SCIELO, 01 referencia en la BDENF y 15 en el LILACS. Conclusión: se observó un aumento de publicaciones relacionadas a los profesionales de la salud en la práctica las políticas de salud pública de los ancianos con principales recomendaciones sobre el desarrollo de políticas públicas que tengan en cuenta las características específicas de los ancianos, facilitando su acceso y que podrían reducir la desigualdad. Mencionan la importancia de la visibilidad del proceso de envejecimiento y la adecuación de las políticas públicas con la ampliación de estrategias que tienen el cuidador como principal sujeto. Descriptores: políticas públicas de salud; ancianos; enfermería.

National public health policies for prevention and care in urinary incontinence in the elderly

1998 ◽  
Vol 16 (S1) ◽  
pp. S71-S73 ◽  
Author(s):  
Hansjoerg Melchior ◽  
Vinod Kumar ◽  
Nancy Muller ◽  
Hanneke van Maanen ◽  
Christine Norton
Keyword(s):  
Public Health ◽  
Urinary Incontinence ◽  
The Elderly ◽  
Health Policies ◽  
Public Health Policies ◽  
National Public Health

scholarly journals The bile acid TUDCA improves glucose homeostasis through increase of insulin levels in mice with Alzheimer's disease

2019 ◽  
Author(s):  
Lucas Zangerolamo ◽  
Helena Cristina de Lima Barbosa Sampaio ◽  
Jean Franciesco Vettorazzi ◽  
Carina Solon ◽  
Gabriela Moreira Soares ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Insulin Resistance ◽  
Alzheimer's Disease ◽  
Bile Acid ◽  
Elderly Population ◽  
Population Studies ◽  
The Elderly ◽  
Insulin Homeostasis ◽  
Aβ Oligomer

Alzheimer's disease (AD) and Type 2 Diabetes Mellitus (T2DM) are two of the most prevalent disorders in the elderly population. Studies suggest that people with T2DM have higher risk of developing AD. Likewise, AD brains presents Insulin resistance resulting in low capacity of glucose uptake. There is a growing evidence that insulin resistance and downstream abnormalities in the insulin signaling pathway are present in the AD brain and contribute to the development of cognitive dysfunction. Here we reported that C57BL/6 mice submitted to intracerebroventricular injection of streptozotocin, model of AD, and treated during 10 days with the bile acid TUDCA presented reduced accumulation of Aβ oligomer in the hippocampus and higher insulin secretion and glucose tolerance, besides improvement in memory test, suggesting that TUDCA treatment interferes with glucose-insulin homeostasis in brain and consequently attenuates AD.

scholarly journals INTEGRALITY IN HEALTH CARE FOR THE ELDERLY: A PUBLIC HEALTH ISSUE

2020 ◽  
Vol 8 (11) ◽  
pp. 311-317
Author(s):  
Mírian Dias Moreira e Silva ◽  
Keidson Rodrigues de Brito ◽  
André Dias Moreira e Silva ◽  
GINA ANDRADE ABDALA ◽  
Maria Dyrce Dias Meira
Keyword(s):  
Public Health ◽  
Health Care ◽  
Population Aging ◽  
The Elderly ◽  
Comprehensive Care ◽  
Health Policies ◽  
Public Health Issue ◽  
Public Health Policies ◽  
Goods And Services ◽  
Care For The Elderly

Introduction: the demands for goods and services aimed at the health needs of the elderly require a different perspective that considers the human being in all its dimensions: biopsychosocial and spiritual. Objective: to reflect on the assistance strategies that impact comprehensive care for the elderly, based on public health policies. Methodology: reflective essay that contextualizes comprehensive care for the elderly. Results: the content is presented in four sections: "Population aging in Brazil" "Public Health Policies: a brief historical recovery"; "Comprehensiveness in health care: practices and challenges" and, finally, "Training to work in the health of the elderly and communication strategies". Conclusion: it is clear that different care strategies, including verbal and non-verbal communication, contribute to greater comprehensiveness and humanization in the care of the elderly. It also appears that public health policies depend on intersectoral integration to provide care for the elderly in a holistic way.

scholarly journals Direct and indirect neurological, cognitive and behavioral effects of COVID-19 on the normal elderly, Mild-Cognitive-Impairment and Alzheimer’s Disease populations

2020 ◽  
Author(s):  
Francesco Iodice ◽  
Valeria Cassano ◽  
Paolo Maria Rossini
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Indirect Effects ◽  
Elderly Population ◽  
Health Resources ◽  
The Elderly ◽  
Recovery Phase ◽  
Healthy Elderly

Abstract This article reviews the main articles that have been published so far about the direct and indirect effects of the COVID-19 pandemic on a particularly fragile population represented by the healthy elderly people as well as those with Mild Cognitive Impairment and Alzheimer's disease. Such populations have been among the most affected in the early stages of the pandemic due to the direct effects of the virus and numerous indirect effects now emerge and will have to be carefully assessed over time. The pandemic associated to COVID-19 has shifted most of the health resources to the emergency area and has consequently left the three main medical areas that dealing with the elderly population (oncology, time-dependent diseases and degenerative disease) temporarily “uncovered”. In the phase following the emergency, it will be crucial to guarantee to each area the economic and organizational resources to quickly return to the level of support of the pre-pandemic state. The emergency phase represented an important moment of discussion on the possibilities of telemedicine which will inevitably become increasingly important but all the limits of its use in the elderly population have to be considered. In the post-lockdown recovery phase, alongside the classic medical evaluation, the psychological evaluation must become even more important for doctors caring about people with cognitive decline.

The role of ubiquitin proteasomal system and autophagy-lysosome pathway in Alzheimer’s disease

2017 ◽  
Vol 28 (8) ◽  
Author(s):  
Yuan Zhang ◽  
Xu Chen ◽  
Yanfang Zhao ◽  
Murugavel Ponnusamy ◽  
Ying Liu
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Protein Degradation ◽  
Molecular Chaperones ◽  
Elderly Population ◽  
Neurodegenerative Disorder ◽  
The Elderly ◽  
Pathological Process ◽  
Β Amyloid

AbstractAlzheimer’s disease (AD) is the most common neurodegenerative disorder leading to dementia in the elderly population. AD is associated with the buildup of β-amyloid and tau, which aggregate into extracellular plaques and neurofibrillary tangles. Although the exact mechanism of pathological process of AD is unclear, the dysfunction of protein degradation mechanisms has been proposed to play an important role in AD. The cellular degradation of abnormal or misfolded proteins consists of three different mechanisms: the ubiquitin proteasomal system (UPS), autophagy-lysosomal pathway (ALP), and interaction of molecular chaperones with UPS or ALP. Any disturbance to these systems causes proteins to accumulate, resulting in pathological process of AD. In this review, we summarize the knowledge of protein degradation pathways in the pathogenesis of AD in light of the current literature. In the future, the regulation UPS or ALP machineries could be the cornerstones of the treatment of AD.

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