scholarly journals Clinical Efficacy of Surgical Treatment in 40 Patients with Acute Hematogenous Osteomyelitis

2020 ◽  
pp. 1-7
Author(s):  
Wang Linan ◽  
Wang Xuewei ◽  
Liu Jian ◽  
Li Yongai ◽  
Wanghui Wanghui ◽  
...  
Keyword(s):  
Clinical Efficacy ◽  
Diagnostic Methods ◽  
Pathological Examination ◽  
Blood Cell Count ◽  
Erythrocyte Sedimentation ◽  
Hematogenous Osteomyelitis ◽  
Acute Hematogenous Osteomyelitis ◽  
Before And After ◽  
Hs Crp ◽  
Esr Imaging

Objective: This study aimed to evaluate the diagnostic methods of acute hematogenous osteomyelitis and the clinical efficacy of fenestration decompression, focus debridement, and convective flushing. Methods: A retrospective analysis was performed on 40 patients with acute hematogenous osteomyelitis admitted to the Department of Orthopedics of our hospital from January 2011 to December 2018. There were 21 males and 19 females, aged 1–70 years, with an average age of 21.45 ± 15.23 years, including 27 children and adolescents. The pathogenic sites were as follows: femur 20 cases, tibia 16 cases, humerus 2 cases, ulna 1 case, and radius 1 case. The systemic and local symptoms of patients before and after surgery were evaluated. The results of white blood cell count (WBC), NEUT%, hs-CRP, erythrocyte sedimentation rate (ESR), imaging examination, bacteriology, and pathological examination were analyzed. Fenestration decompression, focus debridement, and convective flushing were used at the site of lesion in the surgery.

Osteomyelitis

2012 ◽  
Author(s):  
John W. Wilson ◽  
Lynn L. Estes
Keyword(s):  
Bone Destruction ◽  
Signs And Symptoms ◽  
C Reactive Protein ◽  
Blood Cell Count ◽  
Reactive Protein ◽  
Erythrocyte Sedimentation ◽  
Acute Hematogenous Osteomyelitis ◽  
Normal Erythrocyte Sedimentation Rate ◽  
Nuclear Scanning ◽  
Normal Erythrocyte

•Clinical: Localized pain and tenderness of involved bone; systemic signs and symptoms of acute hematogenous osteomyelitis•Radiology: Bone destruction or sequestrum in chronic cases; use of nuclear scanning, magnetic resonance imaging, or computed tomography may aid diagnosis and staging•Laboratory: White blood cell count is often normal; erythrocyte sedimentation rate and C-reactive protein are usually elevated...

Serum C-Reactive Protein, Erythrocyte Sedimentation Rate, and White Blood Cell Count in Acute Hematogenous Osteomyelitis of Children

PEDIATRICS ◽  
1994 ◽  
Vol 93 (1) ◽  
pp. 59-62 ◽  
Author(s):  
Leila Unkila-Kallio ◽  
Markku J.T. Kallio ◽  
Heikki Peltola ◽  
Juhani Eskola
Keyword(s):  
Blood Cell ◽  
Mean Value ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Erythrocyte Sedimentation ◽  
Hematogenous Osteomyelitis ◽  
Acute Hematogenous Osteomyelitis ◽  
The Mean ◽  
Wbc Count ◽  
Time Of Admission

Objective. The aim of this prospective study was to compare the clinical value of the erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), and white blood cell (WBC) count in diagnosis and follow-up of acute hematogenous osteomyelitis in children. Design. Forty-four children aged 2 weeks to 14 years with bacteriologically confirmed acute hematogenous osteomyelitis were examined. Staphylococcus aureus was responsible in 39 cases (89%), Haemophilus influenzae type b in 3 cases (7%), pneumococcus in 1 case (2%), and a microaerophilic streptococcus in 1 case (2%). ESR was measured at the time of admission and on days 3, 5, 7, 10, 14, 19, and 29 of treatment, and CRP was measured on the same days as ESR but also on days 2, 9, 12, 17, and 23. WBC count was examined at the time of admission and on days 5, 10, 19, and 29. Results. ESR was elevated (≥20 mm/h) initially in 92% of the cases; the mean value was 45 mm/h, and the peak values (mean 58 mm/h) were reached on days 3 to 5. After this the levels slowly returned to normal in approximately 3 weeks (mean 18 days). CRP was elevated (>19 mg/L) at the time of admission in 98% of the cases, the mean value being 71 mg/L. The peak CRP value was reached on day 2 (mean 83 mg/L). The decrease was very rapid, normal values being reached within a week (mean 6.9 days). The WBC count was a poor indicator of acute hematogenous osteomyelitis, since only 35% of the children had leukocytosis (WBCs > 12 x 109/L) at the time of admission. Conclusions. In patients with acute hematogenous osteomyelitis, CRP increased and especially decreased significantly faster than ESR, reflecting the effectiveness of the therapy given and predicting recovery more sensitively than ESR or WBC count.

scholarly journals Our experience of total hip arthroplasty in adolescents with consequences of acute hematogenous osteomyelitis

2021 ◽  
Vol 9 (2) ◽  
pp. 163-174
Author(s):  
Khisrav D. Imomov ◽  
Vladimir E. Baskov ◽  
Valentin A. Neverov ◽  
Pavel I. Bortulev
Keyword(s):  
Total Hip Arthroplasty ◽  
Hip Arthroplasty ◽  
Functional Results ◽  
Social Adaptation ◽  
Harris Hip Score ◽  
Control Group ◽  
Total Hip ◽  
Hematogenous Osteomyelitis ◽  
Acute Hematogenous Osteomyelitis ◽  
Before And After

BACKGROUND: Currently, the number of adolescents with terminal stages of coxarthrosis of various origins who underwent total hip joint arthroplasty has increased, as the use of modern implant models with a long service life has narrowed the age limit and expanded the indications for this intervention. AIM: This study aimed to assess the effectiveness of total hip arthroplasty in adolescents with stage 3 coxarthrosis caused by acute hematogenous osteomyelitis. MATERIALS AND METHODS: The study analyzed preoperative data and postoperative clinical, radiological, and functional examination data of 40 patients aged 1318 (15 1.2) years with stage 3 coxarthrosis caused by acute hematogenous osteomyelitis. The study group was composed of 21 (52.5%) boys and 19 (47.5%) girls. The control group consisted of 32 patients with stage 3 post-traumatic coxarthrosis, aged 1218 (15.4 1.7) years, of which 14 (43.75%) were girls and 18 (56.25%) were boys. RESULTS: The long-term functional results were evaluated using the Harris hip score (14). The average Harris hip scores before and after arthroplasty were 44.87 5.65 and 80 7.61 (p 0.05), respectively. In the comparison group, the mean Harris hip scores before and after surgery were 33.73 4.28 and 89.47 5.60 points, respectively (p 0.05). The postoperative follow-up duration was 5 3 M SD (95% confidence interval) years. No complications were observed in the early and late postoperative periods. CONCLUSIONS: In adolescents, total hip arthroplasty is an effective surgical treatment for complications of acute hematogenous osteomyelitis. It quickly provides attainable, stable, and favorable outcomes, which improve the quality of life and social adaptation of adolescents.

Comparison of hs-CRP and Fetuine-A levels before and after the treatment of subjects with subclinical hyperthyroidism

2013 ◽  
Author(s):  
Mehmet Calan ◽  
Oktay Bilgir ◽  
Ferda Bilgir ◽  
Tugba Topcuoglu ◽  
Ozlem Calan
Keyword(s):  
Subclinical Hyperthyroidism ◽  
Before And After ◽  
Hs Crp

DUAL-ENERGY CT WITH XENON IN PATIENTS WITH LUNG PATHOLOGY. FIRST DATA

2018 ◽  
pp. 47-51
Author(s):  
O. E. Karpov ◽  
O. Yu. Bronov ◽  
V. M. Kitaev ◽  
P. S. Vetshev ◽  
D. A. Pikhuta ◽  
...  
Keyword(s):  
Surgical Intervention ◽  
Lung Ventilation ◽  
Dual Energy ◽  
Diagnostic Methods ◽  
Dual Energy Ct ◽  
Lung Pathology ◽  
Preoperative Preparation ◽  
Before And After ◽  
Pulmonary Pathology ◽  
Postoperative Lung Function

Routine diagnostic methods have limitations in terms of predicting the ventilation function of the lungs before and after surgery. It was decided to investigate the possibilities of dual-energy CT (DECT) using xenon in assessment of lung ventilation function.Objective: to master the methods of examination of patients with pulmonary pathology, evaluate the possibility of justifying the volume of operative intervention and prediction of postoperative lung function based on the hybrid images.Materials and methods. For the study, 12 patients with different pulmonary pathologies were selected (COPD – 5, lung cancer – 4, bronchiectasis – 3). Results. It was found that the use of DECT with xenon reflects the functional state of lung tissue.Conclusions. DECT with xenon have potential for planning surgical intervention and introducing the method into modern protocols of preoperative preparation.

scholarly journals Refractory pharyngeal ulceration due to cytomegalovirus in a patient with HIV infection: a case report and literature review

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Morichika Osa ◽  
Akihiro Sato ◽  
Maki Sakagami ◽  
Masaki Machida ◽  
Takao Sato ◽  
...  
Keyword(s):  
Hiv Infection ◽  
Pathological Examination ◽  
Cmv Infection ◽  
Case Presentation ◽  
Immunodeficiency Virus ◽  
Before And After ◽  
Infected Cells ◽  
Immunocompromised Hosts ◽  
Inflammatory Syndrome ◽  
Nonspecific Inflammation

Abstract Background Cytomegalovirus (CMV) is an important pathogen among immunocompromised hosts. Typically, CMV in human immunodeficiency virus (HIV) infection causes diseases of the retina, digestive tract, lungs and liver, but there are few cases of CMV infection of the pharynx and larynx. Case presentation A 57-year-old man with HIV infection was admitted because of pharyngeal pain. Before and after admission, pharyngeal biopsies guided by laryngeal endoscopy were performed four times, but pathological examination showed nonspecific inflammation, and the cause of pharyngeal ulceration was unclear. Additionally, the ulceration deteriorated after initiation of retroviral therapy. Laryngomicrosurgery was conducted under general anesthesia to remove tissue, and pathological diagnosis confirmed CMV infection. Pathological features included enlargement of the cytoplasm and nucleus in infected cells, and intranuclear bodies called owl’s eye inclusions. Ganciclovir dramatically improved the symptoms and laryngoscopic findings. Conclusions This case was diagnosed as pharyngitis and pharyngeal ulceration caused by CMV infection, related to immune reconstitution inflammatory syndrome. In previous reports of CMV-induced pharyngeal or laryngeal ulceration in HIV infection, we found six cases similar to our present case. All cases were diagnosed by biopsy. The present case indicates the importance of biopsy for definitive diagnosis. CMV infection should be considered as a differential diagnosis of pharyngeal ulceration in patients with HIV infection.

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