scholarly journals At the Origins of the Natural Focality Concept

2021 ◽  
pp. 16-25
Author(s):  
MYu Shchelkanov ◽  
GN Leonova ◽  
IV Galkina ◽  
BG Andryukov
Keyword(s):  
Web Of Science ◽  
Far East ◽  
Primorsky Krai ◽  
Basic Principles ◽  
Rights Protection ◽  
Human Wellbeing ◽  
Consumer Rights ◽  
The Far East ◽  
Natural Foci ◽  
Vector Borne

Introduction: The article analyzes the course of scientific research that led to the discovery of tick-borne (Amarillovirales: Flaviviridae, Flavivirus) and Japanese (Amarillovirales: Flaviviridae, Flavivirus) encephalitis viruses and further formulation of the basic principles of functioning of natural foci of vector-borne infections. Materials and methods: We did a literature search in the State Archive of the Primorsky Krai, the Vladivostok City Archive, the Web of Science, PubMed, Scopus, Elsevier, Springer, and Google Scholar databases. Results: In the late 1930s, the Ussuri taiga became a “cradle” of the concept of natural focality first formulated by Academician Yevgeny N. Pavlovsky in 1939. Originally encompassing vector-borne infectious diseases this concept was later expanded to include non-vector-borne infections and sapronoses. A great contribution to the meaningful evolution of the theory of sapronoses was made by Academician Georgy P. Somov (Vladivostok). Conclusion: Establishment in May 1941 of a predecessor of the modern Research Institute of Epidemiology and Microbiology named after G.P. Somovbelonging to the Russian Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing became one of the elements of consistent strengthening of the biological security of the country in the Far East.

scholarly journals Vaccination of cattle in the system of antiepizootic measures in Buryatia

2021 ◽  
pp. 46-52
Author(s):  
O. B. Badmaeva
Keyword(s):  
High Risk ◽  
Infectious Diseases ◽  
Environmental Conditions ◽  
Far East ◽  
Well Being ◽  
Entire Region ◽  
The Far East ◽  
Natural Foci ◽  
Epizootic Process ◽  
The Republic

On the territory of the Republic of Buryatia, six nosological forms of infectious diseases have epizootic significance among cattle. The most widespread are leptospirosis, rabies, and isolated cases of pasteurellosis. Natural foci of rabies were formed, confined to the environmental conditions of the neighboring territories of Mongolia and the TRANS-Baikal territory. Epizootic process tends to polyhostal manifestation with the threat of expanding the focus and complicating the epidemic situation in the entire region of Siberia and the Far East. In 2018 169 heads of cattle were identified with a positive reaction to leptospirosis in 13 administrative districts. Preventive immunization of animals with the control of immunity tension in areas with a high risk of introduction of infectious diseases is the basis for maintaining epizootic well-being throughout the region.

scholarly journals Toxocariasis in children: epidemiological, clinical and laboratory aspects

2020 ◽  
Vol 4 (11) ◽  
pp. 670-675
Author(s):  
A.O. Andreeva ◽  
◽  
N.V. Golovchenko ◽  
A.S. Zhuravlev ◽  
◽  
...  
Keyword(s):  
Peripheral Blood ◽  
Laboratory Data ◽  
Enzyme Linked Immunosorbent Assay ◽  
Blood Eosinophilia ◽  
Rights Protection ◽  
Human Wellbeing ◽  
Consumer Rights ◽  
Positive Rate ◽  
Peripheral Blood Eosinophilia ◽  
Research Institute

Aim: to optimize the diagnosis of toxocariasis based on the analysis of epidemiological, clinical and laboratory data in children with the infestation. Patients and Methods: the analysis of official statistical data for the period of 2014–2018, literature sources, a retrospective analysis of 57 medical records of patients (40 children and 17 adults) who received treatment and diagnostic in the clinic of the Rostov Research Institute of Microbiology and Parasitology of the Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing in 2015–2018 was conducted. Results: a decrease in the incidence of newly diagnosed infestation cases was revealed (registered in the clinic of the Rostov Research Institute of Microbiology and Parasitology of the Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing). It correlated with official statistics (r=0.9, p=0.05). Based on clinical and laboratory examination, the diagnosis was established in 26 patients (45.6%). Among patients with a verified diagnosis of toxocariasis, the proportion of children aged 1 years and 1 months to 10 years old, was 96%. An analysis of epidemiological data showed that 76% of children had close contact with the soil. The infestation occurred in the form of latent toxocariasis in 36% of patients. In more than half of the cases, the disease was clinically manifested by geophagy (56.0%). A permanent laboratory parameter was the eosinophilic leukemoid reaction in patients with toxocariasis. Peripheral blood eosinophilia ranged from 15.66.2±9.31% in latent toxocariasis to 25.5±15.0 % in visceral toxocariasis. The positive rate in ELISA with Toxocara antigen was higher than that in the group of patients with visceral toxocariasis. However, there was no correlation between the eosinophilia level and positive rate (r=0.1, p=0.05). Conclusion: in areas where the incidence of toxocariasis and environmental contamination with invasive helminth eggs are high, it is advisable to perform tests of the peripheral blood in children at least one time per year in the autumn for timely diagnosis of infestation. The use of ELISA with Toxocara antigen is reasonable in the cases of peripheral blood eosinophilia. KEYWORDS: toxocariasis, statistics, incidence, eosinophilia, enzyme-linked immunosorbent assay, Toxocara antigen. FOR CITATION: Andreeva A.O., Golovchenko N.V., Zhuravlev A.S. Toxocariasis in children: epidemiological, clinical and laboratory aspects. Russian Medical Inquiry. 2020;4(11):670–675. DOI: 10.32364/2587-6821-2020-4-11-670-675.

scholarly journals Features of the Epidemiological Situation on Siberian Tick Typhus and other Tick-Borne Ricketsioses in the Russian Federation, Prognosis for 2019

2019 ◽  
pp. 89-97 ◽  
Author(s):  
N. V. Rudakov ◽  
S. N. Shpynov ◽  
D. V. Trankvilevsky ◽  
N. D. Pakskina ◽  
D. A. Savel’ev ◽  
...  
Keyword(s):  
Russian Federation ◽  
Far East ◽  
Laboratory Diagnostics ◽  
The Far East ◽  
Natural Foci ◽  
Causative Agents ◽  
Risk Areas ◽  
The Russian Federation ◽  
Very High ◽  
Epidemiological Situation

The review presents an analysis of the epidemic situation on infections of rickettsial etiology, the causative agents of which are transmitted by Ixodidae ticks in the territory of the Russian Federation. The data obtained through molecular-biological verification allow to unite under the name of “tick-borne ricketsioses” a group of infections caused by R. sibirica subsp. sibirica, R. conorii, R. heilongjiangensis and other species of rickettsiae circulating in natural foci of various regions of Russia. Cases of tick-borne rickettsioses in Siberia and the Far East, caused by various species of rickettsiae, are registered under the name of “Siberian tick-borne typhus” due to the lack of available methods of differential laboratory diagnostics. The paper presents the assessment of the incidence of Siberian tick-borne typhus, indicating not only the varying degrees of epidemic hazard of endemic regions, but also changes in the distribution of risk areas, including the identification of new, epidemically significant foci. In accordance with the risk-oriented approach to prophylaxis, forecasting of epidemic situation on tick-borne rickettsioses was given and differentiation of the endemic territories of the Russian Federation as regards Siberian tick-borne typhus was carried out with distinguishing of epidemiological zones of low, medium, above average, high and very high risk of population infection.

scholarly journals TO THE ORGANIZATION AND CARRYING OUT ACTIVITIES ON CONTROL WITHOUT INTERACTION WITH LEGAL ENTITIES AND INDIVIDUAL ENTREPRENEURS IN THE IMPLEMENTATION OF SOCIO-HYGIENIC MONITORING

2019 ◽  
pp. 4-9
Author(s):  
A.N. Perezhogin ◽  
I.G. Zhdanova-Zaplesvichko
Keyword(s):  
Rights Protection ◽  
Human Wellbeing ◽  
Consumer Rights ◽  
Methodological Approaches ◽  
Legal Entities

We proposed an algorithm for organizing and carrying out activities on control without interacting with legal entities and individual entrepreneurs in the course of state social and hygienic monitoring (SHM). Methodological approaches to the development of the Order of tasks' drawing up for carrying out these activities, the requirements for their content, as well as the drawing up the activities’ results on control without interaction with legal entities and individual entrepreneurs in the course of SHM by specialists of the Federal Service for Surveillance of Consumer Rights Protection and Human Wellbeing were suggested.

scholarly journals To the procedure of confirmation of the laboratory’s competence in performing mutagenicity assessment using the Ames test

2021 ◽  
Vol 29 (4) ◽  
pp. 4-13
Author(s):  
Olga V. Egorova
Keyword(s):  
Ames Test ◽  
Gene Mutations ◽  
Test Substance ◽  
Test Protocol ◽  
Testing Laboratory ◽  
Scientific Center ◽  
Carcinogenic Activity ◽  
Rights Protection ◽  
Human Wellbeing ◽  
Consumer Rights

Introduction. The test for the induction of reverse gene mutations (Ames test, OECD* guideline No. 471) is one of the most popular methods for assessing mutagenicity due to its ease of execution and the ability to detect up to 70-80% of substances with carcinogenic activity. The experimental protocol requires a minimum amount of test substance and standard microbiological laboratory equipment. To obtain the primary data, several days from the start of the experiment are required. Despite the existence of publications devoted to the detailed description of the standard Ames test protocol, there is a gap affecting a number of aspects of the procedure for confirming the competence of a testing center using this method in its practice. Materials and methods. When preparing this article, we used the literature data published in domestic and foreign literature over the past 20 years concerning experimental approaches to the implementation of the Ames test. The literature search was carried out in the Scopus, Medline, Google Scholar, RSCI databases. Results. In the FBES “Federal Scientific Center of Hygiene named after F.F. Erisman” of the Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing the method for assessing the bacterial reverse mutation has found application in assessing the safety of technical products of pesticides, their mixtures and preparative forms, as well as in the examination of equivalence. Testing laboratory center on the basis of the FBES “Federal Scientific Center of Hygiene named after F.F. Erisman” of the Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing is accredited for compliance with the state standard GOST ISO / IEC 17025-2019 ”General requirements for the competence of testing and calibration laboratories.“ In this article, based on new published data and our own practical experience, a number of necessary conditions are considered for demonstrating the competence of a testing laboratory using the test for the induction of reverse gene mutations in its practice, its ability to obtain reliable results and take actions to manage the risks of laboratory activities. The main attention is paid to ensuring such parameters of the test quality as indicator cultures, metabolic activation system, control of the background of spontaneous mutation, etc. Conclusion. The discussed practical issues can be useful for specialists from research laboratories planning to introduce this method into practice.

scholarly journals ELISA diagnostic test systems, serodiagnosis of arboviral infections

2015 ◽  
Vol 20 (6) ◽  
pp. 44-46
Author(s):  
V. F Larichev ◽  
A. A Kozlova ◽  
M. A Saifullin ◽  
N. V Khutoretskaia ◽  
V. M Shkinev ◽  
...  
Keyword(s):  
Dengue Fever ◽  
Neutralizing Antibodies ◽  
Tropical Diseases ◽  
Rights Protection ◽  
Human Wellbeing ◽  
Consumer Rights ◽  
Volgograd Region ◽  
Imported Cases ◽  
Specific Igg ◽  
Regions Of Russia

There are developed and tested by ourselves ELISA kits for serodiagnostics of most endemic to Russia arboviral infections and some imported tropical diseases. Their application allowed in 1999 to set the value WN virus in the etiology of outbreaks ofWN fever in the southern region of Russia, then in Voronezh and Tula regions. From 1999 to 2014, according to the data of Russian Service for Surveillance on Consumer Rights Protection and Human Wellbeing in the Russia there were diagnosed 2284 cases of WNfevers and 1725 cases of CCHF. In 2012-2014 specific IgG and neutralizing antibodies to the WN virus were detected in the population of the Southern and Black earth regions of Russia. Data of the examination of residents ’ sera from Tatarstan, Tver, Ryazan, Kaluga, Kursk and Vologda regions were proved to be negative. In 2000 there were revealedfirst cases of CCHF in the Volgograd region, Kalmykia and Dagestan also. The application of ELISA-IgM kits allowed to reveal cases of Sindbis, Batai, Tahyna, Inkoo, sandfly fevers, Uukuniemi and Bhanja. During the period of2009-2014 there were verified 190 imported cases of dengue fever, Chikungunya, WNfever, sandfly fevers, and Japanese encephalitis among persons returning from travel in tropical countries.

scholarly journals The Activities of Rospotrebnadzor to Ensure the Sanitary and Epidemiological Wellbeing of the Population in a Rapidly Changing External Environment

2021 ◽  
Vol 7 (1) ◽  
pp. 91-98
Author(s):  
O.A. Kulikova ◽  
◽  
Keyword(s):  
Infectious Diseases ◽  
Scientific Knowledge ◽  
External Environment ◽  
Legal Framework ◽  
Living Standards ◽  
Rights Protection ◽  
Human Wellbeing ◽  
Consumer Rights ◽  
New Challenges ◽  
Framework Development

the health of the citizens lies at the heart of any state and presents an immeasurable value. Decent living standards and protection of the population’s health are contingent upon ensuring sanitary and epidemiological wellbeing. The activities of the Russian Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing (Rospotrebnadzor) aim at achieving a consistent improvement of the sanitary and epidemiological wellbeing of the Russian population and are based on the findings of scientific research, legal framework development, and direct cooperation with sole entrepreneurs, individuals, and legal entities. The accumulated scientific knowledge and the multi-year experience in fighting against infectious diseases enable the Service to react swiftly to new challenges, such as the new Coronavirus disease (COVID-19).

scholarly journals Hygiene in supporting scientific and technological development of the country and sanitary and epidemiological welfare of the population (to the 130th anniversary of the Federal Scientific Centre of Hygiene named after F.F. Erisman)

2021 ◽  
Vol 100 (9) ◽  
pp. 882-889
Author(s):  
Anna Yu. Popova ◽  
Gennadii G. Onishchenko ◽  
Valerii N. Rakitskii ◽  
Sergei V. Kuzmin ◽  
Vladislav R. Kuchma
Keyword(s):  
Technological Development ◽  
The Body ◽  
Exploratory Research ◽  
Historical Aspect ◽  
Rights Protection ◽  
Human Wellbeing ◽  
Consumer Rights ◽  
Clean Air ◽  
The Impact ◽  
Scientific And Technological Development

Introduction. Historical analysis is extremely important in assessing the development and achievements of scientific schools and scientific centres. This is especially true concerning research centres operated continuously from the end of the 19th century to almost the first quarter of the 21st century, which include the Federal Scientific Center for Hygiene (FSCH), named after F.F. Erisman of the Federal Service for Supervision of Consumer Rights Protection and Human Wellbeing. The purpose of the study is to analyze the results, achievements and prospects for further development of the FSCH as the head multidisciplinary scientific institution of the Federal Service for Supervision of Consumer Rights Protection and Human Wellbeing (Rospotrebnadzor). Materials and methods. Expert-analytical, historical research has been carried out. Analysis materials include the main results of the centre’s activities in the historical aspect, scientific achievements of the last quarter of a century, plans, directions for ensuring the scientific and technological development of the country in the field of hygiene and health protection, ensuring the sanitary and epidemiological wellbeing of the country’s population. Results. The main stages of the formation and development of the FSCH are associated with scientific and technological revolutions, technical progress, the development of all sectors of the national economy. The results of scientific research have made it possible to establish the nature and extent of the impact of environmental factors, industrial and educational environment on the health of various groups of the population. At the turn of the century, the FSCH got involved in nanomaterials and nanotechnologies hazard assessment. Fundamental studies of the FSCH made it possible to reveal the modern mechanisms of the formation of biocenoses of the environment of new innovative complexes with an assessment of the health risk, to establish the effect of the components of the formulations on the mutagenicity of pesticides. An assessment of the risk to the population due to the complex intake of pesticides into the body is also given. FSCH effectively participates in the implementation of national projects “Demography”, “Ecology”, “Clean Air”. Conclusion. FSCH contributed to the provision of scientific and technological development of the country and the sanitary and epidemiological wellbeing of various population groups. The development of the FSCH is associated with participation in the implementation of fundamental and exploratory research approved by order of the Government of the Russian Federation, sectoral research programs of Rospotrebnadzor, national projects “Demography”, “Ecology”, “Clean Air”, events of the Decade of Childhood (2018-2027).

Sign in / Sign up

Export Citation Format

Share Document