scholarly journals EXPERIMENTAL STUDIES OF THE PROCESS OF LOOSE MATERIAL TRANSPORTATION BY A PNEUMATIC-SCREW CONVEYOR

2021 ◽  
pp. 479-487
Author(s):  
R.B. Hevko ◽  
O.L. Lyashuk ◽  
V.O. Dzyura ◽  
T.A. Dovbush ◽  
O.M. Trokhaniak ◽  
...  
Keyword(s):  
Cross Sections ◽  
Experimental Studies ◽  
Rotation Frequency ◽  
Response Surfaces ◽  
Air Pressure ◽  
Screw Conveyor ◽  
Screw Feeder ◽  
Different Types ◽  
Material Transportation ◽  
Experimental Researches

The article presents the developed design of the pneumatic-screw conveyor, as well as its experimental installation. The method of conducting experimental researches to determine force indicators at movement of different types of loose materials under the influence of air pressure and their volume of various types of bulk materials. Based on the conducted experimental studies, the response surfaces and two-dimensional cross-sections of the pneumatic-screw conveyor productivity when the material passes from the whole area in the hopper transition zone to the screw feeder, its rotation frequency and the working air pressure in the process line have been constructed.

scholarly journals Experimental research of the air permeability of concrete in the compressed zone of the containment for power units no. 1, 2 of the South-Ukrainian NPP

2021 ◽  
Vol 20 ◽  
pp. 39-50
Author(s):  
Ia. A. Zhygalov ◽  
◽  
V. V. Inyushev ◽  
V. O. Posokh ◽  
S. A. Vyzhva ◽  
...  
Keyword(s):  
Experimental Studies ◽  
Air Permeability ◽  
Complex Stress State ◽  
Air Pressure ◽  
Design Basis ◽  
Design Basis Accident ◽  
The Impact ◽  
Experimental Researches ◽  
Maximum Design

The determination of the air permeability of concrete in the compressed zone of NPP’s containment under conditions of excessive air pressure in the subshell space of the reactor compartment under a maximum design basis accident is necessary to confirm the localizing functions of the containment when extending the lifetime of power units. Approaches to determining the localizing ability (air permeability) of concrete in the compressed zone of the containment of NPPs with WWER-1000 type reactors under the impact of excessive air pressure under conditions of maximum design basis accident are discussed in the article. The designed testing installation for experimental studies of the air permeability of concrete by the method of stationary radial filtration is described and the results of experimental researches of the air permeability on the installation are presented for samples simulating the composition of concrete used under construction of the containment for Power Units No. 1, 2 (series B-302 and B-338, respectively) SD “South-Ukrainian NPP”. A comparative analysis of the results of abovementioned experimental researches with the results of experimental and theoretical work on the study of air permeability of the similar samples-imitators of concrete by the method of stationary linear filtration, as well as the results of measurements for samples of concrete sampled directly from the compressed zone of containment for Power Unit No. 2 of SD “South-Ukrainian NPP” was fulfilled. The results are explained by processes of compaction of the concrete structure under a complex stress state that occurs under specific hardening conditions and during longtime compression by pre-stressed reinforcing ropes, which takes place under conditions of real containment operation. It was concluded that the simulators made according to the currently accepted technology cannot provide a correct determination of the localizing ability of the NPP’s containment, since the conditions and time of containment concrete hardening, as well as the longtime constant compressive action of reinforcing ropes, cannot be correctly modeled in full under the formation of samples-imitators. The issue of the containment concrete samplesimitators creating in laboratory conditions requires additional study, improvement of technology and the development of new approaches with maximum physical modeling of the conditions characteristic of the operation of the NPP containment.

3-D reconstruction and analysis of mammalian mitotic spindle structure

1992 ◽  
Vol 50 (1) ◽  
pp. 578-579
Author(s):  
Kent McDonald ◽  
David Mastronarde ◽  
Rubai Ding ◽  
Eileen O'Toole ◽  
J. Richard McIntosh
Keyword(s):  
Cross Sections ◽  
Mitotic Spindle ◽  
Experimental Studies ◽  
Video Camera ◽  
Three Dimensions ◽  
Mitotic Spindles ◽  
Black And White ◽  
Reconstruction Methods ◽  
Spindle Structure ◽  
Tissue Culture Line

Mammalian spindles are generally large and may contain over a thousand microtubules (MTs). For this reason they are difficult to reconstruct in three dimensions and many researchers have chosen to study the smaller and simpler spindles of lower eukaryotes. Nevertheless, the mammalian spindle is used for many experimental studies and it would be useful to know its detailed structure.We have been using serial cross sections and computer reconstruction methods to analyze MT distributions in mitotic spindles of PtK cells, a mammalian tissue culture line. Images from EM negatives are digtized on a light box by a Dage MTI video camera containing a black and white Saticon tube. The signal is digitized by a Parallax 1280 graphics device in a MicroVax III computer. Microtubules are digitized at a magnification such that each is 10-12 pixels in diameter.

Experimental Studies Of Multilayer Glass Structures On Compression, Compression With Bending And Simple Bending

2019 ◽  
pp. 22-30
Keyword(s):  
Cross Section ◽  
Cross Sections ◽  
Applied Load ◽  
Experimental Studies ◽  
Strength Properties ◽  
Research Topic ◽  
Normative Values ◽  
Laminated Glass ◽  
The Cross ◽  
Experimental Values

The work of multilayer glass structures for central and eccentric compression and bending are considered. The substantiation of the chosen research topic is made. The description and features of laminated glass for the structures investigated, their characteristics are presented. The analysis of the results obtained when testing for compression, compression with bending, simple bending of models of columns, beams, samples of laminated glass was made. Overview of the types and nature of destruction of the models are presented, diagrams of material operation are constructed, average values of the resistance of the cross-sections of samples are obtained, the table of destructive loads is generated. The need for development of a set of rules and guidelines for the design of glass structures, including laminated glass, for bearing elements, as well as standards for testing, rules for assessing the strength, stiffness, crack resistance and methods for determining the strength of control samples is emphasized. It is established that the strength properties of glass depend on the type of applied load and vary widely, and significantly lower than the corresponding normative values of the strength of heat-strengthened glass. The effect of the connecting polymeric material and manufacturing technology of laminated glass on the strength of the structure is also shown. The experimental values of the elastic modulus are different in different directions of the cross section and in the direction perpendicular to the glass layers are two times less than along the glass layers.

METHODS FOR SIMULATION OF ACUTE BRAIN ISCHEMIA: PATHOPHYSIOLOGICAL SUBSTANTIATION OF SELECTION AND IMPORTANCE FOR CLINICAL PRACTICE

2019 ◽  
pp. 142-152
Author(s):  
Б.И. Гельцер ◽  
Э.В. Слабенко ◽  
Ю.В. Заяц ◽  
В.Н. Котельников
Keyword(s):  
Clinical Practice ◽  
Experimental Studies ◽  
Cerebrovascular Diseases ◽  
Experimental Models ◽  
Pathological Process ◽  
Ischemic Brain ◽  
Actual Clinical Practice ◽  
Acute Cerebral Ischemia ◽  
Different Types ◽  
Acute Brain Ischemia

Одним из основных требований к разработке экспериментальных моделей цереброваскулярных заболеваний является их максимальная приближенность к реальной клинической практике. В работе систематизированы данные по основным методам моделирования острой ишемии головного мозга (ОИГМ), представлена их классификация, анализируются данные о преимуществах и недостатках той или иной модели. Обсуждаются результаты экспериментальных исследований по изучению патогенеза ОИГМ с использованием различных моделей (полной и неполной глобальной, локальной и мультифокальной ишемии) и способов их реализации (перевязка артерий, клипирование, коагуляция, эмболизация и др.). Особое внимание уделяется «стабильности» последствий острого нарушения мозгового кровообращения: необратимых ишемических повреждений головного мозга или обратимых с реперфузией заданной продолжительности. Отмечается, что важное значение в этих исследованиях должно принадлежать современным методам прижизненной визуализации очагов острого ишемического повреждения, что позволяет оценивать динамику патологического процесса. Предлагаемый метод отвечает требованиям гуманного обращения с животными. Подчеркивается, что выбор релевантной модели ОИГМ определяется задачами предстоящего исследования и технологическими ресурсами научной лаборатории. Development of experimental models for acute forms of cerebrovascular diseases is essential for implementation of methods for their prevention and treatment. One of the principal requirements to such models is their maximum approximation to actual clinical practice. This review systematized major models of acute cerebral ischemia (ACI), their classification, and presented information about their advantages and shortcomings. Also, the review presented results of experimental studies on pathophysiological mechanisms of different types of modeled ACI (complete and incomplete global, local, and multifocal ischemia) and methods for creating these models (arterial ligation, clipping, coagulation, embolization, etc.). Particular attention was paid to “stability” of the consequences of acutely impaired cerebral circulation - an irreversible ischemic brain injury or a reversible injury with reperfusion of a given duration. The authors emphasized that in such studies, a special significance should be given to intravital imaging of acute ischemic damage foci using modern methods, which allow assessing the dynamics of the pathological process and meet the requirements to humane treatment of animals. The choice of a relevant ACI model is determined by objectives of the planned study and the technological resources available at the research laboratory.

CALCULATION OSCILLATIONS OF VARIOUS ELEMENTS OF THE ELASTIC SYSTEM OF THE CENTER-FREE GRINDING MACHINE SASL 5AD

2020 ◽  
pp. 160-165
Author(s):  
Джугурян Т.Г. ◽  
Марчук В.І. ◽  
Марчук І. В.
Keyword(s):  
Horizontal Plane ◽  
Natural Frequencies ◽  
Elastic System ◽  
Experimental Studies ◽  
Piezoelectric Sensors ◽  
Forced Oscillations ◽  
Method Of Calculation ◽  
Vibration Resistance ◽  
Grinding Machine ◽  
Experimental Researches

During the design of operations of centerless intermittent grinding of surfaces there is a need to identify the natural frequencies of oscillations of the elements of the technological system of grinding. The method of calculation of rigidity, vibration resistance and forced oscillations of the elements of the circular grinding machine is offered in the article. Carrying out of experimental researches of rigidity of elastic system of the SASL 5AD grinding machine. We conducted preliminary experimental studies to measure the oscillations of various elements of the elastic system of the SASL 5AD grinding machine in the horizontal plane by piezoelectric sensors during grinding with continuous and discontinuous circles with different geometric parameters.

Geological Field Sketches and Illustrations

2019 ◽  
Author(s):  
Matthew J. Genge
Keyword(s):  
Cross Sections ◽  
Earth Science ◽  
Three Dimensional ◽  
Worked Examples ◽  
Scientific Publications ◽  
Thin Sections ◽  
Geological Features ◽  
Different Types ◽  
The Subject

Drawings, illustrations, and field sketches play an important role in Earth Science since they are used to record field observations, develop interpretations, and communicate results in reports and scientific publications. Drawing geology in the field furthermore facilitates observation and maximizes the value of fieldwork. Every geologist, whether a student, academic, professional, or amateur enthusiast, will benefit from the ability to draw geological features accurately. This book describes how and what to draw in geology. Essential drawing techniques, together with practical advice in creating high quality diagrams, are described the opening chapters. How to draw different types of geology, including faults, folds, metamorphic rocks, sedimentary rocks, igneous rocks, and fossils, are the subjects of separate chapters, and include descriptions of what are the important features to draw and describe. Different types of sketch, such as drawings of three-dimensional outcrops, landscapes, thin-sections, and hand-specimens of rocks, crystals, and minerals, are discussed. The methods used to create technical diagrams such as geological maps and cross-sections are also covered. Finally, modern techniques in the acquisition and recording of field data, including photogrammetry and aerial surveys, and digital methods of illustration, are the subject of the final chapter of the book. Throughout, worked examples of field sketches and illustrations are provided as well as descriptions of the common mistakes to be avoided.

scholarly journals Photoionization Cross-Sections of Carbon-Like N+ Near the K-Edge (390–440 eV)

Atoms ◽  
2021 ◽  
Vol 9 (2) ◽  
pp. 27
Author(s):  
Jean-Paul Mosnier ◽  
Eugene T. Kennedy ◽  
Jean-Marc Bizau ◽  
Denis Cubaynes ◽  
Ségolène Guilbaud ◽  
...  
Keyword(s):  
High Resolution ◽  
Cross Section ◽  
Cross Sections ◽  
Experimental Studies ◽  
Photoionization Cross Section ◽  
Theoretical Work ◽  
Rydberg Series ◽  
R Matrix ◽  
Resonance Strengths ◽  
Nitrogen Ion

High-resolution K-shell photoionization cross-sections for the C-like atomic nitrogen ion (N+) are reported in the 398 eV (31.15 Å) to 450 eV (27.55 Å) energy (wavelength) range. The results were obtained from absolute ion-yield measurements using the SOLEIL synchrotron radiation facility for spectral bandpasses of 65 meV or 250 meV. In the photon energy region 398–403 eV, 1s⟶2p autoionizing resonance states dominated the cross section spectrum. Analyses of the experimental profiles yielded resonance strengths and Auger widths. In the 415–440 eV photon region 1s⟶(1s2s22p2 4P)np and 1s⟶(1s2s22p2 2P)np resonances forming well-developed Rydberg series up n=7 and n=8 , respectively, were identified in both the single and double ionization spectra. Theoretical photoionization cross-section calculations, performed using the R-matrix plus pseudo-states (RMPS) method and the multiconfiguration Dirac-Fock (MCDF) approach were bench marked against these high-resolution experimental results. Comparison of the state-of-the-art theoretical work with the experimental studies allowed the identification of new resonance features. Resonance strengths, energies and Auger widths (where available) are compared quantitatively with the theoretical values. Contributions from excited metastable states of the N+ ions were carefully considered throughout.

scholarly journals Melatonin in Cancer Treatment: Current Knowledge and Future Opportunities

Molecules ◽  
2021 ◽  
Vol 26 (9) ◽  
pp. 2506
Author(s):  
Wamidh H. Talib ◽  
Ahmad Riyad Alsayed ◽  
Alaa Abuawad ◽  
Safa Daoud ◽  
Asma Ismail Mahmod
Keyword(s):  
Clinical Trials ◽  
Current Knowledge ◽  
Biological Activities ◽  
Experimental Studies ◽  
Therapeutic Effects ◽  
Cell Proliferation Inhibition ◽  
Different Types ◽  
Solid Foundation

Melatonin is a pleotropic molecule with numerous biological activities. Epidemiological and experimental studies have documented that melatonin could inhibit different types of cancer in vitro and in vivo. Results showed the involvement of melatonin in different anticancer mechanisms including apoptosis induction, cell proliferation inhibition, reduction in tumor growth and metastases, reduction in the side effects associated with chemotherapy and radiotherapy, decreasing drug resistance in cancer therapy, and augmentation of the therapeutic effects of conventional anticancer therapies. Clinical trials revealed that melatonin is an effective adjuvant drug to all conventional therapies. This review summarized melatonin biosynthesis, availability from natural sources, metabolism, bioavailability, anticancer mechanisms of melatonin, its use in clinical trials, and pharmaceutical formulation. Studies discussed in this review will provide a solid foundation for researchers and physicians to design and develop new therapies to treat and prevent cancer using melatonin.

scholarly journals Identification of N-glycans with GalNAc-containing antennae from recombinant HIV trimers by ion mobility and negative ion fragmentation

2021 ◽  
Author(s):  
David J. Harvey ◽  
Anna-Janina Behrens ◽  
Max Crispin ◽  
Weston B. Struwe
Keyword(s):  
Cross Sections ◽  
Ion Mobility ◽  
Travelling Wave ◽  
Negative Ion ◽  
Ion Fragmentation ◽  
Structural Identity ◽  
Immunodeficiency Virus ◽  
Different Types ◽  
Complex Glycans ◽  
Ion Collision

AbstractNegative ion collision-induced dissociation (CID) of underivatized N-glycans has proved to be a simple, yet powerful method for their structural determination. Recently, we have identified a series of such structures with GalNAc rather than the more common galactose capping the antennae of hybrid and complex glycans. As part of a series of publications describing the negative ion fragmentation of different types of N-glycan, this paper describes their CID spectra and estimated nitrogen cross sections recorded by travelling wave ion mobility mass spectrometry (TWIMS). Most of the glycans were derived from the recombinant glycoproteins gp120 and gp41 from the human immunodeficiency virus (HIV), recombinantly derived from human embryonic kidney (HEK 293T) cells. Twenty-six GalNAc-capped hybrid and complex N-glycans were identified by a combination of TWIMS, negative ion CID, and exoglycosidase digestions. They were present as the neutral glycans and their sulfated and α2→3-linked sialylated analogues. Overall, negative ion fragmentation of glycans generates fingerprints that reveal their structural identity.

Application of Thermo-Frictional and Chemical-Thermal Methods Treatments for Surface Strengthening of Materials

2021 ◽  
Vol 1038 ◽  
pp. 93-99
Author(s):  
Alexander Levterov ◽  
Julia Nechitailo ◽  
Tatyana Plugina ◽  
Oleg Volkov
Keyword(s):  
Cross Sections ◽  
Experimental Studies ◽  
Metallographic Analysis ◽  
Thermal Treatments ◽  
Strengthening Effect ◽  
Thermal Methods ◽  
Surface Strengthening ◽  
Before And After ◽  
The Cross

In the article, the issues of using the methods of thermo-frictional and chemical-thermal treatments for surface strengthening of steel tools were disclosed. 65G steel and U8A steel were considered. A flat graver and a cylindrical root roller were considered to be tools in need of hardening. The nature of the jewellery work using such a tool has been described. Hardening techniques, experimental studies and macro photographs of the samples were presented in this article. A detailed metallographic analysis and measurement of the microhardness of the cross-sections of the prototypes after their strengthening using various methods was carried out. The metallographic nature of the reinforcement with the formation of surface "white layers" was shown. Comparison of the properties of the samples before and after strengthening was carried out. Conclusions about the strengthening effect of the thermo-frictional and chemical-thermal methods of strengthening were made.

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