scholarly journals HUBUNGAN ANTARA PENYAKIT ARTERI PERIFER DENGAN FAKTOR RISIKO KARDIOVASKULAR PADA PASIEN DM TIPE 2

e-CliniC ◽  
2013 ◽  
Vol 1 (1) ◽  
Author(s):  
Maria Simatupang ◽  
Karel Pandelaki ◽  
Agens L. Panda

Abtract: Peripheral arterial disease (PAD) is one of the complications that occurs in patients with type 2 diabetes mellitus due to the process of atherosclerosis. Age, hypertension, obesity, LDL cholesterol, and smoking are the cardiovascular risk factors that can be found in diabetes patients. Ankle brachial index (ABI) is a simple way to confirm the diagnosis of PAD. This study used a cross sectional design. The subjects numbered 100 patients with type 2 diabetes mellitus who were examined in the Metabolic Endocrine Clinic of Prof. Dr. R.D Kandou Hospital. Data of variables were based on the patients’ medical records, interviews about smoking, and blood pressures measured on ​​legs and arms in a supine position. A Chi-square test showed that there was a correlation between blood pressure and ABI values ​​(P = 0.049). Moreover, there was no correlation between risk factors of age (P = 0.144), obesity (P = 0.488), LDL cholesterol (P = 0.197), and smoking (P = 0.512) with ABI values. Multivariate analysis showed that there was a significant correlation between blood pressures and ABI values ​​(P = 0.037). Conclusion: From all the examined cardiovascular risks, the most correlated with the incidence of PAD in patients with type 2 diabetes mellitus was blood pressure. Keywords: cardiovascular risk factors, PAD, type 2 diabetes mellitus Abstrak: Penyakit Arteri Perifer (PAP) merupakan salah satu komplikasi yang terjadi pada pasien diabetes melitus tipe 2 (DMT2) akibat proses aterosklerosis. Usia, hipertensi, obesitas, kadar kolesterol LDL dan merokok merupakan faktor risiko kardiovaskular yang dapat ditemukan pada pasien diabetes. Ankle Brachial Index (ABI) merupakan cara sederhana untuk mendiagnosis PAP. Penelitian ini menggunakan desain cross sectional. Subjek dalam penelitian ini berjumlah 100 pasien DMT2 yang melakukan pemeriksaan di Poliklinik Endokrin Metabolik RSUP Prof.Dr.R.D. Kandou Manado. Pengukuran variabel berdasarkan pada catatan rekam medik pasien, anamnesis riwayat merokok, dan pengukuran nilai tekanan darah kaki maupun tangan dalam posisi berbaring. Uji chi-square menunjukkan bahwa terdapat hubungan bermakna antara tekanan darah dan nilai ABI (P = 0,049), sedangkan faktor risiko usia (P = 0,144), obesitas (P = 0,488), kolesterol LDL (P = 0,197) dan riwayat merokok (P = 0,512) tidak didapati adanya hubungan. Analisis multivariat, menunjukkan bahwa terdapat hubungan yang sangat bermakna antara tekanan darah dengan nilai ABI (P = 0,037). Simpulan: Dari semua faktor risiko kardiovaskular yang di teliti, tekanan darah yang paling berhubungan dengan kejadian PAP pada pasien DMT2. Kata kunci: DMT2, faktor risiko kardiovaskular, PAP

2014 ◽  
Vol 3 (1) ◽  
Author(s):  
Fadma Yuliani ◽  
Fadil Oenzil ◽  
Detty Iryani

AbstrakPenyebab mortalitas dan morbiditas utama pada pasien diabetes mellitus (DM) tipe 2 adalah penyakit jantung koroner (PJK) dimana penderitanya dua sampai empat kali lebih berisiko terkena penyakit jantung dari pada non DM. Mekanisme terjadinya PJK pada DM tipe 2 dikaitkan dengan adanya aterosklerosis yang dipengaruhi oleh berbagai faktor. Penelitian ini bertujuan mengetahui hubungan berbagai faktor risiko terhadap kejadian PJK pada penderita DM tipe 2. Penelitian dilaksanakan di RSUP. Dr. M. Djamil Padang dan RS. Khusus Jantung Sumbar pada bulan Maret-Agustus 2013. Penelitian bersifat analitik dengan desain cross sectional comparative. Jumlah sampel 176 orang yang terdiri dari 88 orang penderita DM dengan PJK dan 88 orang DM tanpa PJK. Pengolahan data dilakukan dengan uji chi-square menggunakan sistem komputerisasi. Hasil Penelitian menunjukkan bahwa faktor risiko yang berhubungan dengan kejadian PJK pada penderita DM tipe 2 adalah jenis kelamin (p=0,000), lama menderita DM (p=0,043), hipertensi (p=0,007), dislipidemia (p=0,000), obesitas (p=0,023), dan merokok (p=0,000). Kesimpulan: Terdapat hubungan yang sangat bermakna (p<0,0001) antara jenis kelamin, dislipidemia, dan merokok dengan kejadian PJK pada penderita DM tipe 2 dan terdapat hubungan yang bermakna (p<0,05) antara lama menderita DM, hipertensi, obesitas dengan kejadian PJK pada penderita DM tipe 2.Kata kunci: DM tipe 2, PJK, faktor risikoAbstractThe main causes of mortality and morbidity in type 2 diabetes mellitus (DM) patients is coronary heart disease (CHD) which adults who suffer from DM are two to four times have the risk of heart disease than people without DM. The mechanism of CHD in DM is associated with the presence of atherosclerosis that influenced by various factors. This research has aims to determine the relationship of risk factors for CHD incident in patients with DM. The study was conducted in the Dr. M. Djamil Padang and Cardiac Hospital of West Sumatra from March to August 2013. This research is an analytic study with comparative cross-sectional design. There are 176 DM patient samples that consist of 88 CHD patients and 88 patients without CHD. The data processing used chi-square test by computerized system. The result showed that risk factors that were related with CHD incident in DM patients are gender (p=0,000), long-suffering diabetes (p=0,043), hypertension (p=0,007), dyslipidemia (p=0,000), obesity (p=0,023), and smoking habit (p=0,000). Conclusion: There are marked significant (p<0,0001) relationship between gender, dyslipidemia, and smoking habit with CHD incident in DM patients and significant relationship (p<0,05) between long-suffering diabetes, hypertension, and obesity with CHD incident in DM patients.Keywords: type 2 diabetes mellitus, CHD, risk factor


2017 ◽  
pp. 35-44
Author(s):  
Dinh Toan Nguyen

Background: Studies show that diabetes mellitus is the greatest lifestyle risk factor for dementia. Appropriate management and treatment of type 2 diabetes mellitus could prevent the onset and progression of mild cognitive impairment to dementia. MoCA test is high sensitivity with mild dementia but it have not been used and studied widespread in Vietnam. Aim: 1. Using MoCA and MMSE to diagnose dementia in patients with type 2 diabetes mellitus. 2. Assessment of the relationship between dementia and the risk factors. Methods: cross-sectional description in 102 patients with type 2 diabetes mellitus. The Mini-Mental State Examination(MMSE) and the Montreal Cognitive Assessment (MoCA) were used to assess cognitive function. The diagnosis of dementia was made according to Diagnostic and Statistical Manual of Mental Disorders. Results: The average value for MoCA in the group of patients with dementia (15.35 ± 2.69) compared with non-dementia group (20.72 ± 4.53). The sensitivity and specificity of MoCA were 84.8% and 78.3% in identifying individuals with dementia, and MMSE were 78.5% and 82.6%, respectively. Using DSMIV criteria as gold standard we found MoCA and MMSE were more similar for dementia cases (AUC 0.871 and 0.890). The concordance between MoCA and MMSE was moderate (kappa = 0.485). When considering the risk factors, the education,the age, HbA1c, dyslipidemia, Cholesterol total related with dementia in the type 2 diabetes. Conclusion: MoCA scale is a good screening test of dementia in patients with type 2 diabetes mellitus.When compared with the MMSE scale, MoCA scale is more sensitive in detecting dementia. Key words: MoCA, dementia, type 2 diabetes mellitus, risk factors


Sains Medika ◽  
2015 ◽  
Vol 6 (1) ◽  
pp. 12
Author(s):  
Citta Arunika Risyudhanti ◽  
Agung Sulistyanto ◽  
Suparmi Suparmi

Introduction: Hearing impairment due to cochlear damage is one complication of Type 2 Diabetes Mellitus (DM2). Objective: This study aims to determine the relationship between duration of DM2 with hearing impairment.Method: The analytic observasional study with the cross sectional design using the medical record of DM2 outpatient in internal clinic of Islamic Sultan Agung Hospital Semarang and also pure tone audiometric examination’s record in Otorynolaryngology clinic of Islamic Sultan Agung Hospital Semarang.31 medical records of DM2 patients were meeting the inclusion and exclusion criteria. The data consist of 18 medical records of patients with less than6 years duration of DM2, and 13 medical records of patients with more than 6 years duration of DM2. The pure tone audiometry was used to classified the hearing impairment. The data analysis was conducted using SPSS 20.0. The correlation between the duration of DM2 and hearing impairment was analyzed using Chi Square test. The significance relation between the duration of DM type 2 and hearing impairment was analyzed using cooficient contigency, with significance of < 0.05. Result: hearing impairment’s distribution frequency on tested ears in Sultan agung Islamic Hospital Semarang were 27 ears having SNHL type (43,5%), 19 ears having CHL (30,6%) and 16 ears were normal (25,8%), p = 0,02 (p < 0,05). Conclusion: There is a weak correlation between the DM 2 duration and the incidence of hearing impairment in Sultan Agung Islamic Hospital Semarang.


2021 ◽  
Author(s):  
Qi Dai ◽  
Nan Chen ◽  
Ling Zeng ◽  
Xin-Jie Lin ◽  
Feng-Xiu Jiang ◽  
...  

Abstract Background: Normoalbuminuric diabetic kidney disease (NADKD) is a newly defined DKD, the clinical features and pathogenesis for which are still being understood. This study aimed to investigate the features and risk factors for NADKD in patients with type 2 diabetes mellitus (T2DM).Methods: A retrospective cross-sectional study was conducted. The related clinical and laboratory data of patients with T2DM hospitalized between August 2012 and January 2020 were collected for statistical analysis. We classified the patients with T2DM into four groups on the basis of the presence or absence of albuminuria and reduced estimated glomerular filtration rate (eGFR). Analysis of variance, the Kruskal–Wallis test, and the chi-square test were used to compare the groups. Binary logistic regression analyses with a forward stepwise method were performed to explore the risk factors for renal dysfunction in hospitalized patients with normoalbuminuric T2DM.Results: Among the 1620 patients evaluated, 500 (30.9%) had DKD, of which 9% had NADKD. The prevalence of stroke, cardiovascular events, carotid plaque, and peripheral arterial disease in NADKD was significantly higher than in a non-DKD control group (normoalbuminuric T2DM patients with eGFR of ≥60 ml/min/1.73 m2). Regression analyses revealed that three significant independent factors were associated with NADKD: age (OR = 1.089, confidence interval [CI] 95% [1.055−1.123], p < 0.001), previous use of renin−angiotensin system inhibitors (RASIs; OR = 2.330, CI 95% [1.212−4.481], p = 0.011), and glycated hemoglobin (HbA1c; OR = 0.839, CI 95% [0.716−0.983], p = 0.03). Conclusions: NADKD is mainly associated with macrovascular rather than microvascular complications. NADKD is more common in patients with normoalbuminuric T2DM with older age, previous use of RASIs, and good glycemic control.


2017 ◽  
Vol 70 (2) ◽  
pp. 265-270 ◽  
Author(s):  
José Cláudio Garcia Lira Neto ◽  
Mayra de Almeida Xavier ◽  
José Wicto Pereira Borges ◽  
Márcio Flávio Moura de Araújo ◽  
Marta Maria Coelho Damasceno ◽  
...  

ABSTRACT Objective: to identify the prevalence of Metabolic Syndrome and its components in a population of patients with type 2 Diabetes Mellitus. Method: a cross-sectional study was conducted with 201 diabetic patients. A descriptive analysis and Chi-square and Fisher's exact tests ( p <0.05) were performed. Results: the majority of participants were females and overweight, with a mean age of 63.1 years and a low level of education, and categorized as physically inactive. Of all individuals investigated, 50.7% were diagnosed with Metabolic Syndrome and 92% had at least one of the syndrome components with values beyond those recommended. Conclusion: it is essential to take preventive actions and develop studies that help to identify the factors associated with this syndrome.


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