scholarly journals KASUS KROMOBLASTOMIKOSIS PADA SEORANG PEREMPUAN

2015 ◽  
Vol 7 (1) ◽  
Author(s):  
Mariani V. Lasut ◽  
Rita S. Tanamal ◽  
Grace M. Kapantow
Keyword(s):  
Tissue Culture ◽  
Physical Examination ◽  
Histopathological Examination ◽  
Fungal Culture ◽  
Fonsecaea Pedrosoi ◽  
Patient Will ◽  
The Right ◽  
Histopathology Examination ◽  
Hard Consistency ◽  
Test Tissue

Abstract: Chromoblatomycosis is a chronic fungal infection in the skin and subcutaneus tissue caused by pigmented fungi. It occurs most in males in tropical and subtropical countries. The causal fungi were found isolated in woods, decomposed plants, and soil.  Early lesions manifest as papules that become hypertrophy plaques, and in years they develop to become hyperkeratotic masses. Chromoblastomycosis is difficult to treat. We reported a female of 37 years with lesions on the right foot for 20 years in the forms of plaques, papulonodules, multiple verrucous lesions. Lesions had hard consistency and were associated with erosion, crustae, and minimal pus. Several supporting tests were carried out. KOH 20% test resulted in sclerotic bodies; fungal culture revealed Fonsecaea pedrosoi; and histopathological examination showed chronic granulomatous inflamation. The patient was treated with itraconazole 2 x 200 mg daily, which was planned for 8-12 months. After 2 months of treatment, the lesions improved. Conclusion: Based on anamnesis, physical examination, KOH test, tissue culture, and histopathology examination, this case was diagnosed as chromoblatomycosis. Fonsecaea pedrosoi was found as the causative agent. Oral antimycotic itrakonazole 2 x 200 mg/day showed lesion improvement after 2 months of treatment. The patient will be evaluated until full treatment  has been achieved. Keywords: chromoblastomycosis, Fonsecaea pedrosoi, itrakonazole     Abstrak: Kromoblastomikosis merupakan infeksi jamur kronis pada kulit dan jaringan subkutan, disebabkan jamur berpigmen, umumnya pada laki-laki, banyak ditemukan di daerah tropis/subtropis, terisolasi di lingkungan dari kayu, sisa tanaman, dan tanah. Lesi awal berupa papul yang membesar membentuk plak hipertrofi dalam beberapa tahun menjadi massa hiperkeratotik. Kromoblastomikosis sukar disembuhkan. Kami melaporkan seorang perempuan 37 tahun dengan lesi pada kaki kanan sejak 20 tahun lalu berupa plak, papulonodul, verukous multipel, konsistensi keras, disertai erosi, krusta, pus yang minimal. Pada pemeriksaan KOH 20% didapatkan badan sklerotik, pemeriksaan kultur jamur ditemukan Fonsecaea pedrosoi, histopatologis menunjukkan radang kronik granulomatik. Terapi itrakonazole 2x200 mg/hari akan diberikan selama 8–12 bulan. Setelah 2 bulan pengobatan terdapat perbaikan. Simpulan: Pada kasus ini, diagnosis kromoblastomikosis ditegakkan berdasarkan anamnesis, pemeriksaan fisik, dan pemeriksaan penunjang berupa KOH, kultur jaringan, dan histopatologi. Hasil kultur menunjukkan Fonsecaea pedrosoi sebagai penyebab kromoblastomikosis. Pemberian antimikotik oral itrakonazole 2 x 200 mg/hari menunjukkan perbaikan setelah 2 bulan pengobatan. Evaluasi akan terus dilanjutkan sampai pengobatan selesai. Kata kunci: kromoblastomikosis, Fonsecaea pedrosoi, itrakonazole

scholarly journals Seminoma and sertolioma in non-cryptorchid dog – case report

2021 ◽  
Vol 15 (4) ◽  
pp. 281-286
Author(s):  
Guilherme Mantuani Silva ◽  
Isabela Cristina de Oliveira ◽  
Rodrigo Samuel de Toledo ◽  
Juliana Evangelista Bezerril ◽  
Gabriela Maria Benedetti Vasques ◽  
...  
Keyword(s):  
Physical Examination ◽  
Ultrasound Examination ◽  
Histopathological Examination ◽  
Seminiferous Tubules ◽  
Biochemical Tests ◽  
Predisposing Factor ◽  
Left Testicle ◽  
Spindle Cells ◽  
Mixed Breed ◽  
The Right

The most common testicular neoplasms in dogs are seminoma, leydigocytoma and sertolioma, affecting middle--aged and elderly dogs, where cryptorchidism is a predisposing factor, as well as some breeds. It can occur alone or, less fren-quently, concurrently, generally affecting the same testicle. This study aimed to report the case of a non-cryptorchid 14-year--old mixed breed dog diagnosed with seminoma and sertolioma, each in a testicle. The animal showed an increase in scrotal volume, with no changes in other clinical parameters on physical examination. On ultrasound examination, it was possible to observe alterations suggestive of neoplasia in both testicles and prostatic alteration suggestive of benign prostatic hyperplasia. Complementary blood count and biochemical tests were performed and, as treatment, orchiectomy was performed. Fragments were collected from both testicles and sent for histopathological examination. Microscopy of the left testicle showed the presence of round cells, multiple and evident nucleoli, cells in different phases of mitosis and binucleation, these changes being compa-tible with seminoma. In contrast, in the right testicle, spindle and elongated cells (pseudo-lobular) were observed, presence of long cytoplasmic projections with rounded ovoid nucleus, spindle cells and degeneration of seminiferous tubules, compatible with sertolioma. It was observed that physical examination associated with ultrasound was efficient to detect the presence of neoplasms, being validated by histopathological examination. Orchiectomy was an assertive treatment indicated for this case.

scholarly journals Fibroadenoma in axillary supernumerary breast: case report

2005 ◽  
Vol 123 (5) ◽  
pp. 253-255 ◽  
Author(s):  
Délio Marques Conde ◽  
Renato Zocchio Torresan ◽  
Eiji Kashimoto ◽  
Luiz Eduardo Campos de Carvalho ◽  
Cássio Cardoso Filho
Keyword(s):  
Case Report ◽  
Physical Examination ◽  
Outpatient Clinic ◽  
Breast Tissue ◽  
Histopathological Examination ◽  
Local Pain ◽  
Gynecology And Obstetrics ◽  
Patient Reported ◽  
Design Case ◽  
The Right

CONTEXT: Supernumerary breast tissue may be affected by the same diseases and alterations that compromise topical breast tissue. Nevertheless, reports of fibroadenoma in supernumerary breast tissue in the axillae are rare. OBJECTIVE: To describe a case of fibroadenoma in an axillary supernumerary breast. DESIGN: Case report. CASE REPORT: A 39-year-old woman was referred to the gynecology and obstetrics outpatient clinic at Hospital Estadual Sumaré, complaining of bilateral axillary masses. The patient reported cosmetic problems and local pain and discomfort. On physical examination, alterations compatible with bilateral axillary accessory breasts, without palpable nodules, were observed. Supplementary examinations (mammography and ultrasonography) revealed a 1.1 cm mass in the right axillary breast. The patient underwent resection of the supernumerary breasts and histopathological examination revealed fibroadenoma of the right axillary breast tissue.

scholarly journals Natural infection by Microsporum canis in a capuchin monkey

2017 ◽  
Vol 47 (6) ◽  
Author(s):  
Stéphanie Machado Mota ◽  
Adriano Fernandes Ferreira ◽  
Thiago Lopes Nery ◽  
Roberto Citelli de Farias ◽  
Amanda Figueiredo Mangueira ◽  
...  
Keyword(s):  
Physical Examination ◽  
Effective Treatment ◽  
Natural Infection ◽  
Skin Lesions ◽  
Capuchin Monkey ◽  
Microsporum Canis ◽  
Fungal Culture ◽  
Hind Limbs ◽  
The Right ◽  
Pruritic Skin

ABSTRACT: This paper described a case of a capuchin monkey (Sapajus libidinosus) with non-pruritic skin lesions. During the physical examination, multifocal areas of alopecia with crusts, erythema and scaling compatible with dermatophytosis were reported on the right fore and hind limbs and on tail. Fungal culture findings revealed a diagnosis of dermatophytosis due to Microsporum canis. The animal was successfully treated with itraconazole. This is the first report of a dermatophytosis case in S. libidinosus and the first description of an effective treatment in this species.

scholarly journals Kanker Paru: Laporan Kasus

2020 ◽  
Vol 2 (1) ◽  
Author(s):  
Junita Joseph ◽  
Linda W. A. Rotty
Keyword(s):  
Lung Cancer ◽  
Physical Examination ◽  
Ct Scan ◽  
Malignant Tumors ◽  
Histopathological Examination ◽  
Bronchial Carcinoma ◽  
Bronchial Epithelium ◽  
Breath Sounds ◽  
The Right ◽  
Thorax Ct

Abstract: In general, lung cancer is all kinds of malignancy of the lung. It consists of malignancy derived from the lung itself (primary) and from out of the lung (metastasis). Clinically, primary lung cancers are malignant tumors derived from bronchial epithelium (bronchial carcinoma). Lung cancer is the main cause of death due to malignancy worldwide. We reported a male of 55-year-old male diagnosed as lung cancer. Diagnosis was based on anamnesis, physical examination, and supporting investigations. Anamnesis included smoking for 10 years ±15 cigarettes/day and complaints of shortness of breath, coughing, chest pain radiating to the back, and significant weight loss. Physical examination revealed enlargement of the right supraclavicular gland and decreased breath sounds in the right lung at the fifth intercostal space. Thorax photo, thorax CT-scan, and histopathological examination confirmed the diagnosis of lung cancer (adeno-carcinoma). Chemotherapy was administered with a combination of gemcitabine-cisplatin regimens for 12 cycles. The prognosis of this patient was poor because the disease had reached stage 4. However, the patient felt some clinical improvement after one month of chemotherapy.Keywords: lung cancer Abstrak: Kanker paru dalam arti luas adalah semua penyakit keganasan di paru, mencakup keganasan yang berasal dari paru sendiri (primer) maupun keganasan dari luar paru (metastasis). Dalam pengertian klinis yang dimaksud dengan kanker paru primer adalah tumor ganas yang berasal dari epitel bronkus (karsinoma bronkus). Kanker paru merupakan penyebab utama kematian akibat keganasan di dunia Kami melaporkan sebuah kasus kanker paru pada seorang laki-laki berusia 55 tahun. Diagnosis ditegakkan berdasarkan anamnesis, pemeriksaan fisik, dan pemeriksaan penunjang yang meliputi adanya riwayat merokok (sigaret) selama 10 tahun sebanyak ±15 batang rokok/hari, dengan sesak nafas, batuk, nyeri dada menjalar sampai ke punggung, dan penurunan berat badan yang nyata. Pada pemeriksaan fisik didapatkan pembesaran kelenjar supraklavikular kanan dan suara nafas menurun pada paru kanan setinggi sela iga V. Pada pemeriksaan penunjang foto toraks, thorax CT-scan, dan histopatologik didapatkan hasil yang menyokong diagnosis kanker paru (adenokarsinoma). Pada pasien ini, telah diberikan penata-laksanaan kemoterapi dengan kombinasi regimen gemcitabine-cisplatin selama 12 siklus. Progno-sis pasien ini buruk karena sudah sampai pada stadium 4, namun dengan kemoterapi yang dijalani sampai saat ini selama 1 bulan, pasien merasakan adanya perbaikan secara klinis.Kata kunci: kanker paru

scholarly journals Pulmonary Phaehyphomycosis in Retroviral Disease Patient

2021 ◽  
Vol 5 (0-2) ◽  
pp. 17
Author(s):  
Ummu Afeera Binti Zainulabid ◽  
Muhammad Naimmuddin Bin Abdul Azih ◽  
Sasi Kumar A/L Maniyam ◽  
Azliana Binti Abd Fuaa ◽  
Mohd Radhwan Bin Abidin ◽  
...  
Keyword(s):  
Viral Load ◽  
Histopathological Examination ◽  
Disease Patient ◽  
Significant Loss ◽  
Middle Lobe ◽  
Fungal Culture ◽  
Follicular Hyperplasia ◽  
Lateral Segment ◽  
Black Fungi ◽  
The Right

Pulmonary phaeohyphomycosis is a rare infection in the lung caused by black fungi containing a cytoplasmic melanin-like pigment. A 42-year-old man with underlying retroviral disease on HAART was investigated for having constitutional symptoms. Despite undetectable viral load and a high CD4 count, he was found to have unexplained significant loss of weight and appetite over a period of 6 months. Clinical examination revealed a cachexic man with multiple inguinal lymphadenopathies. Excisional biopsy of the inguinal lymph node revealed reactive follicular hyperplasia. CT Thorax, Abdomen and Pelvis was arranged to look for occult malignancy or infection and he was found to have multiple non-enhancing subcentimeter lung nodules mainly at the lateral segment of the right middle lobe of his lung. The largest nodule measured about 0.8 x 1.5 x 0.5 (AP x W x CC), with some nodules having an irregular margin with no extension into the adjacent bronchi. Bronchoscopy was done and demonstrated a black patch at the right intermedius, lateral segment of the middle lobe which did not disappear upon bronchial flush or wash. Histopathological examination found focal areas of blackish pigment and the bronchial alveolar lavage sent for fungal culture grew Cladosporium species. The patient was treated with oral Itraconazole with marked clinical improvement. This case highlights an unusual black fungi infection in the lung that stands out not only for its rarity and it's responsiveness to treatment, but also the susceptibility of an RVD positive patient to this infection despite having suppressed viral load and normal CD4 count.International Journal of Human and Health Sciences Supplementary Issue-2: 2021 Page: S17

Popliteal artery thrombosis secondary to a tibial osteochondroma

VASA ◽  
2011 ◽  
Vol 40 (3) ◽  
pp. 251-255 ◽  
Author(s):  
Gruber-Szydlo ◽  
Poreba ◽  
Belowska-Bien ◽  
Derkacz ◽  
Badowski ◽  
...  
Keyword(s):  
Case Report ◽  
Magnetic Resonance Angiography ◽  
Popliteal Artery ◽  
Doppler Ultrasonography ◽  
Histopathological Examination ◽  
Previous History ◽  
Plain Radiography ◽  
Artery Thrombosis ◽  
History Of ◽  
The Right

Popliteal artery thrombosis may present as a complication of an osteochondroma located in the vicinity of the knee joint. This is a case report of a 26-year-old man with symptoms of the right lower extremity ischaemia without a previous history of vascular disease or trauma. Plain radiography, magnetic resonance angiography and Doppler ultrasonography documented the presence of an osteochondrous structure of the proximal tibial metaphysis, which displaced and compressed the popliteal artery, causing its occlusion due to intraluminal thrombosis..The patient was operated and histopathological examination confirmed the diagnosis of osteochondroma.

TUMOR GANAS OVARIUM RESIDIF METASTASIS KARSINOMA MUSIN KE UMBILIKUS, PERITONEUM, DAN CAIRAN ASITES TANPA DITEMUKAN TANDA KEGANASAN PADA PEMERIKSAAN HISTOPATOLOGIS PASCA OPERATIF SEBELUMNYA

2019 ◽  
Vol 3 (2) ◽  
pp. 130-136
Author(s):  
Arif Fadillah ◽  
Andi Friadi
Keyword(s):  
Ovarian Carcinoma ◽  
Ovarian Tumor ◽  
Malignant Tumors ◽  
Histopathological Examination ◽  
Ovarian Tumors ◽  
Postoperative Chemotherapy ◽  
Definitive Treatment ◽  
Malignant Ovarian Tumor ◽  
Patient Will ◽  
Optimal Debulking

Background : Malignant ovarian tumor are still the number one cause of death and the second most  of incidents for gynecological malignant tumors. The principles of management of ovarian cancer are the same as the principles of handling other malignant diseases, for the treatment of primary lesions operatively and the handling of potential sites of tumor metastases with chemotherapy. Histopathological examination is still considered a gold standard for diagnosis and definitive treatment of malignant ovarian tumors. If histopathologic results are obtained, then the patient will be planned to undergo postoperative chemotherapy. The mismatch between the preoperative and intraoperative clinical features, and the results of postoperative histopathological examination is a problem in managing cases of ovarian malignant tumors.Objective : Report a case of residive ovarian carcinoma with no appearance of malignancy marker in the previous postoperative histopathological examination.Method : Case reportCase : We report the case of a 45-year-old woman with a history of two previous laparotomy. The first operation was carried out in February 2014 on the indication of an extra ovarian cyst, resulting in the impression of a "Follicular Cysts" based on histopathological examination. The second operation was performed in March 2015, performed surgical staging tumors with an indication of malignant ovarian tumors with clinical metastases, but from histopathological examination it was found that "Cystadenoma Ovarii Muscinosum Multiloculare" and "no visible signs of malignancy", so the patient was not managed with postoperative chemotherapy. In April 2019 patients came with complaints of new mass growth, from CT-Scan and USG investigations there was a suspicious impression of a residive ovarian tumor with metastases into the omentum and massive ascites. On May 16, 2019 an optimal debulking was performed with the findings of residive mass, ascites, and mass metastases in the intra operative peritoneum. From the results of histopathological examination, it was found that "Muscinous Carcinoma with metastases to the umbilicus, peritoneum, and ascitic fluidKeywords: Malignant residive ovarian tumor, mucinous ovarian carcinoma

Successful Control of a Co-Infection Caused by Candida albicans and Pseudomonas aeruginosa in Keratitis

2020 ◽  
Vol 20 ◽  
Author(s):  
Debarati Paul ◽  
Suman Saha ◽  
Neelam Singh ◽  
Jayansgu Sengupta ◽  
Santi M. Mandal
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Candida Albicans ◽  
Histopathological Examination ◽  
Specific Interaction ◽  
Major Threat ◽  
Effective Combination ◽  
Male Farmer ◽  
Successful Control ◽  
The Right ◽  
Corneal Button

Introduction: Nowadays, co-infection by interspecific organisms is major threat in infection control. To identify the effective combination of drugs to control the keratitis caused by Candida albicans with Pseudomonas aeruginosa are attributed in this study. Materilas and Methods: The patient of a 47 years old male farmer with infection in the right eye which showed redness and watering was treated with fortified cefazolin and fortified tobramycin before referral. No pigmentation or vascularisation was noted. The excised corneal button was also subjected to microbiological and histopathological examination. Results: A rare case of keratitis caused by co-infection of Candida albicans with Pseudomonas aeruginosa was identified. Results confirmed the inter-specific interaction of the two microorganisms. Conclusion: Cases of co-infection by Candida and Pseudomonas are not abundantly reported and difficult to treat. In this case, treatment involved Amphotercin-B and ciprofloxacin, effectively eradicated the infection. This therapy may be successfully implied for such cases of co-infection in future.

Biochemical and Histopathological Evaluation of the Radioprotective Effects of Melatonin Against Gamma Ray-Induced Skin Damage

2019 ◽  
Vol 12 (1) ◽  
pp. 72-81 ◽  
Author(s):  
Dheyauldeen Shabeeb ◽  
Masoud Najafi ◽  
Ahmed Eleojo Musa ◽  
Mansoor Keshavarz ◽  
Alireza Shirazi ◽  
...  
Keyword(s):  
Gamma Ray ◽  
Histopathological Examination ◽  
Radical Scavenging ◽  
Limiting Factor ◽  
Skin Damage ◽  
Exposed Skin ◽  
Male Wistar Rats ◽  
Time Periods ◽  
Skin Damages ◽  
The Right

Background:Radiotherapy is one of the treatment methods for cancers using ionizing radiations. About 70% of cancer patients undergo radiotherapy. Radiation effect on the skin is one of the main complications of radiotherapy and dose limiting factor. To ameliorate this complication, we used melatonin as a radioprotective agent due to its antioxidant and anti-inflammatory effects, free radical scavenging, improving overall survival after irradiation as well as minimizing the degree of DNA damage and frequency of chromosomal abrasions.Methods:Sixty male Wistar rats were randomly assigned to 4 groups: control (C), melatonin (M), radiation (R) and melatonin + radiation (MR). A single dose of 30 Gy gamma radiation was exposed to the right hind legs of the rats while 40 mg/ml of melatonin was administered 30 minutes before irradiation and 2 mg/ml once daily in the afternoon for one month till the date of rat’s sacrifice. Five rats from each group were sacrificed 4, 12 and 20 weeks after irradiation. Afterwards, their exposed skin tissues were examined histologically and biochemically.Results:In biochemical analysis, we found that malondialdehyde (MDA) levels significantly increased in R group and decreased significantly in M and MR groups after 4, 12, and 20 weeks, whereas catalase (CAT) and superoxide dismutase (SOD) activities decreased in the R group and increased in M and MR groups during the same time periods compared with the C group (p<0.05). Histopathological examination found there were statistically significant differences between R group compared with the C and M groups for the three different time periods (p<0.005, p<0.004 and p<0.004) respectively, while R group differed significantly with MR group (p<0.013). No significant differences were observed between C and M compared with MR group (p>0.05) at 4 and 20 weeks except for inflammation and hair follicle atrophy, while there were significant effects at 12 weeks (p<0.05).Conclusion:Melatonin can be successfully used for the prevention and treatment of radiation-induced skin injury. We recommend the use of melatonin in optimal and safe doses. These doses should be administered over a long period of time for effective radioprotection and amelioration of skin damages as well as improving the therapeutic ratio of radiotherapy.

scholarly journals Stereotactic Body Radiotherapy of a Solitary Metachronous Sphenoid Metastasis from Renal Cell Cancer: A Case Report

2021 ◽  
pp. 269-273
Author(s):  
Charles Marchand Crety ◽  
Estelle Vigneau ◽  
Camille Invernizzi
Keyword(s):  
Renal Cell Cancer ◽  
Renal Cell ◽  
Stereotactic Body Radiation Therapy ◽  
Clinical Presentation ◽  
Histopathological Examination ◽  
Cell Cancer ◽  
Papillary Renal Cell Carcinoma ◽  
Complete Response ◽  
Resonance Imaging ◽  
The Right

Nasosinus metastases from kidney cancer are an unusual clinical presentation although some cases are reported in the literature. Among these cases, sphenoidal metastases are even rarer. Here we report a case of lone sphenoid metastasis in patients with papillary renal cell cancer. Eight months after radical nephrectomy, the patient presented with progressively worsening diplopia. Magnetic resonance imaging showed a mass in the right sphenoid sinus. Histopathological examination of the biopsy sample confirmed diagnosis of sinonasal metastasis from papillary renal cell carcinoma. The patient was declined for surgical management and received stereotactic body radiation therapy. Reassessment MRI at 4 months showed a complete response of the treated sphenoid lesion.

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