scholarly journals ROLE OF BERA IN EVALUATION OF HEARING LOSS IN PEDIATRIC AGE POPULATION

2019 ◽  
pp. 1-2
Author(s):  
Rajendra K. Teharia ◽  
Rukmini Sharma* ◽  
N .C. Purohit ◽  
Jayant KUMAR
Keyword(s):  
Hearing Loss ◽  
High Risk ◽  
Early Diagnosis ◽  
Hearing Impairment ◽  
Screening Tool ◽  
Pediatric Population ◽  
Early Age ◽  
Learning Abilities ◽  
Early Diagnose

Introduction: Hearing impairment in pediatric population specially in early age could affect their learning abilities, skills and communication. Early diagnosis is utmost important in these cases to prevent this disability permanently. Aims: In this study, we evaluate the role of BERA in early diagnosis of hearing impairment specially in high risk pediatric population. Materials and methods: A total 65 high risk cases below 12 years of age are included in the study and BERA was obtained and data obtained and analysed. Results: In our study, 40.9 % cases showed hearing impairment on BERA investigation. Severe to modied hearing loss was found in 2 4 cases (88.9 %). Conclusion: In our study, BERA is very simple, useful, reliable, screening tool specially in high risk and un-cooperative pediatric population for early diagnose and management of hearing loss.

A Community Based High Risk Register for Hearing Loss

1982 ◽  
Vol 47 (4) ◽  
pp. 373-375 ◽  
Author(s):  
James L. Fitch ◽  
Thomas F. Williams ◽  
Josephine E. Etienne
Keyword(s):  
Hearing Loss ◽  
System Identification ◽  
High Risk ◽  
Language Learning ◽  
Education Program ◽  
Communication System ◽  
Auditory Signal ◽  
Early Age ◽  
Community Based ◽  
Children With Hearing Loss

The critical need to identify children with hearing loss and provide treatment at the earliest possible age has become increasingly apparent in recent years (Northern & Downs, 1978). Reduction of the auditory signal during the critical language-learning period can severely limit the child's potential for developing a complete, effective communication system. Identification and treatment of children having handicapping conditions at an early age has gained impetus through the Handicapped Children's Early Education Program (HCEEP) projects funded by the Bureau of Education for the Handicapped (BEH).

scholarly journals Developing of a Simple Screening Tool for Opportunistic COPD Case Finding

QJM ◽  
2020 ◽  
Vol 113 (Supplement_1) ◽  
Author(s):  
Y M Mohamed ◽  
S H Sharkawy ◽  
D I Darwish
Keyword(s):  
High Risk ◽  
Early Detection ◽  
Early Diagnosis ◽  
Outpatient Clinic ◽  
World Wide ◽  
Screening Tool ◽  
Case Finding ◽  
Screening Questionnaire ◽  
Risk Patients ◽  
Simple Screening

Abstract Background Under diagnosis of COPD is serious problem in many countries world-wide because there are no generally detection tools available to detect high-risk patients for spirometry, and patients will not go for COPD check-up until a serious issue happens like exacerbation. Objective The aim of the work is trying to assess a new screening tool for early diagnosis of COPD. Patients and Methods The present study was conducted upon 500 subjects during the period from march 2018 to august 2018 who admitted to our chest department or visit our outpatient clinic, employees and visitors to Ain Sham hospitals.All subjects >40yrs who smoker or ex-smoker(≥10pack-years) applied a six variants(age,sex,packed years smoked during life ,dyspnea,chronic phlegmand chronic cohgh)questionnaire modified from PUMA questionnaire Subjects with score ≥5 did spirometry Results 500 subjects shared in the study 497 of them were males ( 99.4% )and 3 were females (.6%). 152of them(30.4%) had score <5 and 348 of them (69.6%)had score ≥5 who did spirometry.152 subjects did not perform spirometry. By spirometry we diagnosed 81(23.3) case COPD (fev1-fvc <.7) out of 348 subjects under gone spirometry and 16.2% of total subjects(500) . Conclusion Modified puma score is a simple and easy screening questionnaire for early detection of COPD cases and spirometry should be done to confirm the diagnosis or rule out.COPD is prevalent in many healthy apparent persons.

The Role of Music Intensity in Aerobics: Implications for Hearing Conservation

2003 ◽  
Vol 14 (01) ◽  
pp. 029-038 ◽  
Author(s):  
Wayne J Wilson ◽  
Nicole Herbstein
Keyword(s):  
Hearing Loss ◽  
High Risk ◽  
High Intensity ◽  
High Impact ◽  
Temporary Threshold Shift ◽  
Previous Knowledge ◽  
Hearing Conservation ◽  
Post Class ◽  
Motivation To Work

Aerobics becomes an at-risk activity for noise-induced hearing loss (NIHL) when high intensity music is played in its classes. Attempts to reduce this risk through hearing conservation have generally failed, possibly because participants find the high intensity music enjoyable and motivating, and therefore not "too loud". To investigate this further, the median noise (music) intensities in four high impact aerobics classes were fixed at 80, 85, 89 and 97 dB(A), rated as very low, low, at and high-risk for temporary threshold shift (TIS) and NIHL respectively, and participant (n=236) responses were measured via a post-class questionnaire. The results showed noise (music) intensity was related to perceived music loudness, enjoyment and motivation to work (p<0.001). Also, perceived music loudness, enjoyment and motivation to work were related to each other (p<0.001), but not to previous knowledge that exposure to loud sounds can permanently damage hearing (p>0.05). These results, and their implications on hearing conservation in aerobics, were discussed.

scholarly journals Old gene, new phenotype: splice-altering variants in CEACAM16 cause recessive non-syndromic hearing impairment

2018 ◽  
Vol 55 (8) ◽  
pp. 555-560 ◽  
Author(s):  
Kevin T Booth ◽  
Kimia Kahrizi ◽  
Hossein Najmabadi ◽  
Hela Azaiez ◽  
Richard JH Smith
Keyword(s):  
Hearing Loss ◽  
Hearing Impairment ◽  
Loss Of Function ◽  
Bioinformatics Pipeline ◽  
Exon 2 ◽  
Reading Frame ◽  
Sequencing Platform ◽  
Syndromic Hearing Impairment ◽  
Generation Sequencing

BackgroundHearing loss is a genetically and phenotypically heterogeneous disorder.ObjectivesThe purpose of this study was to determine the genetic cause underlying the postlingual progressive hearing loss in two Iranian families.MethodsWe used OtoSCOPE, a next-generation sequencing platform targeting >150 genes causally linked to deafness, to screen two deaf probands. Data analysis was completed using a custom bioinformatics pipeline, and variants were functionally assessed using minigene splicing assays.ResultsWe identified two homozygous splice-altering variants (c.37G>T and c.662–1G>C) in the CEACAM16 gene, segregating with the deafness in each family. The minigene splicing results revealed the c.37G>T results in complete skipping of exon 2 and loss of the AUG start site. The c.662–1G>C activates a cryptic splice site inside exon 5 resulting in a shift in the mRNA reading frame.ConclusionsThese results suggest that loss-of-function mutations in CEACAM16 result in postlingual progressive hearing impairment and further support the role of CEACAM16 in auditory function.

scholarly journals Role of a serum-based biomarker panel in the early diagnosis of lung cancer for a cohort of high-risk patients

Cancer ◽  
2015 ◽  
Vol 121 (S17) ◽  
pp. 3113-3121 ◽  
Author(s):  
Da-Wei Yang ◽  
Yong Zhang ◽  
Qun-Ying Hong ◽  
Jie Hu ◽  
Chun Li ◽  
...  
Keyword(s):  
Lung Cancer ◽  
High Risk ◽  
Early Diagnosis ◽  
High Risk Patients ◽  
Biomarker Panel ◽  
Risk Patients ◽  
Diagnosis Of Lung Cancer

scholarly journals Objective screening of hearing impairment using brainstem evoked response audiometry in children below 5 years of age and assessing the high risk factors

2018 ◽  
Vol 4 (4) ◽  
pp. 923 ◽  
Author(s):  
Mallikarjun Patil ◽  
Prakash Handi ◽  
K. R. Prasenkumar ◽  
Kranti Gouripur
Keyword(s):  
Risk Factors ◽  
Hearing Loss ◽  
Risk Factor ◽  
High Risk ◽  
Hearing Impairment ◽  
Hearing Threshold ◽  
Evoked Response ◽  
Common Risk Factor ◽  
High Risk Factors ◽  
Evoked Response Audiometry

<p class="abstract"><strong>Background:</strong> Hearing impairment is a common disability in children. This study is to evaluate the common high risk factors for hearing loss in our locality and to estimate hearing threshold by brain stem evoked response audiometry.</p><p class="abstract"><strong>Methods:</strong> 100 children under five years were subjected to brainstem evoked response audiometry. Wave V morphology was studied and hearing threshold estimated. The high risk factor(s) were analysed and degree of hearing impairment assessed.  </p><p class="abstract"><strong>Results:</strong> 38 children were found to have hearing impairment. Most of the children had bilateral hearing impairment. Of them 30 children (79%) had profound hearing loss. Consanguineous marriage was the most common risk factor.</p><p class="abstract"><strong>Conclusions:</strong> Since consanguinity is the most common risk factor, health education and genetic counselling will help to decrease the incidence of autosomal recessive nonsyndromic deafness. Improvement in immunization for rubella can decrease the hearing impairment due to these infections. Due to availability of medical facilities hearing impairment due to perinatal factors have decreased.</p>

Galactosaemia

1987 ◽  
Vol 5 (3-4) ◽  
pp. 175-188 ◽  
Author(s):  
L B. Sardharwalla ◽  
J. E. Wraith
Keyword(s):  
High Risk ◽  
Early Diagnosis ◽  
Mental Development ◽  
Diagnosis And Treatment ◽  
Early Age ◽  
Biochemical Genetics ◽  
Classical Galactosaemia ◽  
Eventual Outcome ◽  
Very High

This paper reviews galactosaemia and describes the experience of the Willink Biochemical Genetics Unit in the management of classical galactosaemia. Galactokinase and UDPgalactose-4-epimerase deficiency are dealt with briefly. The former disorder is readily treated with a galactose free diet and if this is started early in life, the only complication, cataracts, is avoided. Epimerase deficiency is a relatively ‘new’ disorder and little is known about the eventual outcome of affected patients. Early observations suggest that the prognosis is likely to be poor even in those patients diagnosed and treated soon after birth. Classical galactosaemia leads to a number of long term complications. The prognosis for normal mental development in affected patients is poor. Unfortunately this does not appear to be reversible by early diagnosis and treatment and whilst every effort should be made to establish an early diagnosis our experience suggests that there is no difference in the ultimate mental development between those who are detected within the first two weeks of life and those before the age of six weeks. In addition female homozygotes are at a very high risk of developing ovarian failure at an early age.

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