PREVALENCE OF METABOLIC SYNDROME IN FIRST EPISODE DRUG NAÏVE SCHIZOPHRENIA PATIENTS

2021 ◽  
pp. 41-43
Author(s):  
Alok Kumar Sinha ◽  
Amitabh Saha ◽  
Chandrima Bhattacharya ◽  
Sanjay Kumar
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Tertiary Care ◽  
First Episode ◽  
Western India ◽  
Care Hospital ◽  
Glucose Levels ◽  
Drug Naïve

BACKGROUND: It is well established that schizophrenia is associated with higher morbidity and mortality due to the nature of illness itself and cardiovascular risk factors. Among cardiovascular risk factors metabolic syndrome has been discussed extensively in psychiatric literature. However most of the studies focused on the recent pharmacological interventions are possible etiological factors of metabolic syndrome. In our study we are trying to nd out any association of metabolic syndrome with schizophrenia in drug naïve patients. METHOD: Eighty consecutive drug naïve rst episode patients with schizophrenia presenting at a tertiary care hospital in Western India were studied. They were assessed for prevalence of metabolic syndrome as per the criteria set by the NCEP (ATPIII) in Adults. RESULT: A high prevalence of metabolic syndrome in drug naïve rst episode patients with schizophrenia was found as compared to that in general population. CONCLUSION: There should be mandatory screening for the possibility of hyperlipidemia, high glucose levels and metabolic syndrome in drug naïve rst episode patients with schizophrenia before prescribing antipsychotic drugs

scholarly journals EPICARDIALADIPOSE TISSUE THICKNESS IN PATIENTS WITH METABOLIC SYNDROME AND ITS ASSOCIATION WITH CARDIOVASCULAR RISK FACTORS.

2020 ◽  
pp. 26-28
Author(s):  
Jayanta Saha ◽  
Kuntal Bhattacharyya ◽  
Shravan Kumar ◽  
Debarshi Jana
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
Cardiovascular Risk ◽  
Observational Study ◽  
Sample Size ◽  
Cardiovascular Risk Factors ◽  
Tertiary Care ◽  
International Diabetes Federation ◽  
Care Hospital ◽  
Cross Sectional

INTRODUCTION Metabolic syndrome is a constellation of several cardiovascular risk factors, and is defined by the National Cholesterol Education Program (NCEP) Adult Treatment Panel (ATP) III criteria (2001) or the International Diabetes Federation (IDF) criteria (2005). 1, 2The prevalence of metabolic syndrome varies between 24.6 - 41% in different parts of Indian subcontinent and based on different criteria for metabolic syndrome. OBJECTIVES To assess epicardial adipose tissue (EAT) thickness by echocardiography in patients with metabolic syndrome, and find out if there is any association between EAT thickness and different cardiovascular risk factors. MATERIALS AND METHODS This cross-sectional observational study was conducted in a tertiary care hospital in India among patients attending the Medicine and Cardiology out-patient department (OPD) during the study period of six months from May 2018 to October 2018. Patients satisfying the diagnostic criteria of metabolic syndrome as per the IDF criteria (2005) were included in the study, as there are separate cut off points for waist circumference for South Asian population. Design: Cross-sectional observational study. Setting: Single centre study in a tertiary care teaching hospital. Participants: Initially 450 patients with metabolic syndrome as per International Diabetes Federation (IDF) criteria (2005) were screened. Patients having age above 65 years, deranged liver/renal function, ischemic heart disease, heart failure, malignancy, pregnancy, ascitis, poor echo window, history of endocrine disorders like Cushing Syndrome, glucocorticoid use, having any acute illness and those not giving consent were excluded. Final sample size was 397. For defining the normal EAT thickness in this geographic region, 50 age and gender matched healthy volunteers without any conventional cardiovascular risk factors (except age in some cases) acted as controls. Study period was six months. RESULT The mean value of EAT thickness in the control group was 2.97 (± 0.86) mm, hence the upper reference limit of EAT thickness in this study was taken as more than mean + 2SD, i.e. 4.69mm. Mean EAT thickness in patients suffering from metabolic syndrome was 5.48 ± 0.83 mm, which was significantly increased compared to controls. Taking 4.69mm as cut off, it was seen that 311 (78.34%) patients had increased EAT thickness >4.69mm. CONCLUSION Further studies with larger sample size and longitudinal design are required to establish the ability of EAT thickness to predict cardiovascular risk.

Cardiovascular risk factors among bipolar disorder patients admitted to an inpatient unit of a tertiary care hospital in India

2014 ◽  
Vol 10 ◽  
pp. 51-55 ◽  
Author(s):  
Sandeep Grover ◽  
Naresh Nebhinani ◽  
Subho Chakrabarti ◽  
Ajit Avasthi ◽  
Debasish Basu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Bipolar Disorder ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Inpatient Unit ◽  
Care Hospital

scholarly journals Prevalence of cardiovascular risk factors and diseases in patients with osteoarthritis of knee attending orthopaedic out-patient department of a tertiary care hospital

2019 ◽  
Vol 6 (9) ◽  
pp. 3699
Author(s):  
Kunal Ajitkumar Shah ◽  
Anuradha Mohapatra ◽  
Gajanan D. Velhal
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Physical Inactivity ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Tobacco Consumption ◽  
Care Hospital ◽  
Unhealthy Diet

Background: Osteoarthritis (OA) and cardio-vascular diseases (CVD) share similar risk factors. Since OA may increase the risk of CVD through several mechanisms, this study was taken up to find the prevalence of cardiovascular risk factors and diseases in patients with OA knee. We also assessed the relationship between cardiovascular risk factors and the socio-demographic characteristics of the participants.Methods: This cross-sectional study was conducted during August 2018 to January 2019 in an Orthopaedic Out-patient Department of a tertiary care hospital in a metropolitan city. Sample size was 384. Patients above the age of 45 years who were radiologically diagnosed to be OA knee grade 2 and above were included. Questionnaire was used to collect data. Lipid profile and blood sugar were done. Perceived stress scale-10 was used for calculating stress level.Results: Physical inactivity was the most prevalent risk factor (79.68%) followed by tobacco consumption (69.27%), obesity (64.84%), unhealthy diet (56.77%), positive family history (48.43%), dyslipidaemia (48.17%), diabetes (38.54%), hypertension (27.60%), smoking, mental stress and excessive alcohol intake. Prevalence of CVDs like heart failure, heart attack, stroke and other cerebral atherosclerotic conditions were 5.98%. Prevalence among male and female was 6.16% and 5.88% respectively.Conclusions: Risk factors for cardiovascular diseases are common in patients of Osteoarthritis Knee. Physical inactivity is the most common risk factor followed by tobacco consumption, obesity and unhealthy diet. Prevalence of CVDs were 5.98%.

Clinical and Biochemical Study of Hypoandrogenic Metabolic Syndrome in the Cardiovascular Risk Content of Male Patients

2017 ◽  
Vol 54 (1) ◽  
pp. 137-140
Author(s):  
Ana Minodora Grozdan ◽  
Oana Paduraru ◽  
Rodica Ghiuru ◽  
Costinela Georgescu ◽  
Letitia Duceac
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Biochemical Study ◽  
Male Hypogonadism ◽  
Male Patients

The aim of this study was to determine the incidence of hypoandrogenenic to male patients with S.Met., in the context of cardiovascular risk factors. It performed description of a correlation with diagnostic components of S.Met., and specifying an interrelated male hypogonadism with each of the major cardiovascular risk factors.

scholarly journals Dietary Fiber and Its Source Are Associated with Cardiovascular Risk Factors in Korean Adults

Nutrients ◽  
2021 ◽  
Vol 13 (1) ◽  
pp. 160
Author(s):  
SuJin Song ◽  
YoonJu Song
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Dietary Fiber ◽  
Abdominal Obesity ◽  
Dietary Quality ◽  
Fruit Consumption ◽  
Total Dietary Fiber ◽  
Korean Adults

We examined the associations of dietary fiber and its source with cardiovascular risk factors in Korean adults. This cross-sectional study involved 16,792 adults from the 2013–2018 Korea National Health and Nutrition Examination Survey data. Dietary data were obtained using a 24 h recall method and used to evaluate intakes of total dietary fiber and its source and fruit consumption. Cardiovascular risk factors included obesity, abdominal obesity, metabolic syndrome, hypercholesterolemia, hypertension, and type 2 diabetes. Multiple logistic regression was used to examine the associations of dietary fiber and its source with cardiovascular risk factors by sex. Total fiber and fruit fiber intake in men were inversely associated with metabolic syndrome (Q5 vs. Q1: odds ratios (OR) = 0.69, 95% confidence intervals (CI) = 0.53–0.92 for total fiber; Q4 vs. Q1: OR = 0.76, 95% CI = 0.61–0.93 for fruit fiber). Among women, a higher intake of fruit fiber was related to a reduced prevalence of obesity (Q4 vs. Q1: OR = 0.85, p trend = 0.029) and abdominal obesity (Q4 vs. Q1: OR = 0.82, p trend = 0.026). Total fruit and whole fruit consumption was inversely associated with obesity, abdominal obesity, and metabolic syndrome in men and hypertension in women. The amount and sources of fiber are associated with metabolic diseases in Korean adults and should be considered in the context of overall dietary quality.

Investigation of the prevalence of cardiovascular risk factors in obese patients diagnosed with metabolic syndrome in childhood and examination of left ventricular function by echocardiography

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Güzin Özden ◽  
Ayşe Esin Kibar Gül ◽  
Eda Mengen ◽  
Ahmet Ucaktürk ◽  
Hazım Alper Gürsu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Insulin Resistance ◽  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Left Ventricular ◽  
Atherogenic Index ◽  
Volume Index ◽  
Common Component

Abstract Objectives The objective of this study is to investigate the cardiovascular risk factors associated with metabolic syndrome (MetS), which is increasingly becoming prevalent in childhood obesity. Methods A total of 113 patients, 76 of whom were between the ages of 10 and 17 (mean age: 14.5 ± 1.8 years) and diagnosed with obesity (30 non-MetS and 46 MetS using IDF) and 37 of whom constituted the control group, participated in the study. Echocardiographic examination and atherogenicity parameters (Atherogenic index of plasma [AIP: logTG/HDL], total cholesterol/HDL, and TG/HDL ratio and non-HDL) were evaluated. Results The most common component accompanying obese MetS was found to be hypertension and low HDL. While obesity duration, body mass index (BMI), blood pressure, fasting insulin, insulin resistance, atherogenicity parameters were determined to be significantly higher in the obese-MetS group. Echocardiography showed that while the thickness, volume, and diameter of LV end-diastolic wall, left ventricular mass (LVM), LVM index (LVMI g/m2) and relative wall thickness (RWT) were significantly high in the MetS group, however, mitral E/A ratio was significantly lower (p<0.05). Change in LV geometry consistent with concentric remodeling (increased RWT, normal LVMI) was visible in obese groups. LVM were positively significantly related to BMI, waist circumference, insulin resistance, blood pressure, LDL level, and negative to mitral E/A ratio. In the obese-MetS group, LVMI was positively correlated to office systolic BP, left atrium end-diastolic volume/index. Conclusions LVMI and atherogenicity parameters that were found to be significantly higher in obese MetS exhibit increased cardiovascular risk in childhood.

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