scholarly journals EPICARDIALADIPOSE TISSUE THICKNESS IN PATIENTS WITH METABOLIC SYNDROME AND ITS ASSOCIATION WITH CARDIOVASCULAR RISK FACTORS.

2020 ◽  
pp. 26-28
Author(s):  
Jayanta Saha ◽  
Kuntal Bhattacharyya ◽  
Shravan Kumar ◽  
Debarshi Jana
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
Cardiovascular Risk ◽  
Observational Study ◽  
Sample Size ◽  
Cardiovascular Risk Factors ◽  
Tertiary Care ◽  
International Diabetes Federation ◽  
Care Hospital ◽  
Cross Sectional

INTRODUCTION Metabolic syndrome is a constellation of several cardiovascular risk factors, and is defined by the National Cholesterol Education Program (NCEP) Adult Treatment Panel (ATP) III criteria (2001) or the International Diabetes Federation (IDF) criteria (2005). 1, 2The prevalence of metabolic syndrome varies between 24.6 - 41% in different parts of Indian subcontinent and based on different criteria for metabolic syndrome. OBJECTIVES To assess epicardial adipose tissue (EAT) thickness by echocardiography in patients with metabolic syndrome, and find out if there is any association between EAT thickness and different cardiovascular risk factors. MATERIALS AND METHODS This cross-sectional observational study was conducted in a tertiary care hospital in India among patients attending the Medicine and Cardiology out-patient department (OPD) during the study period of six months from May 2018 to October 2018. Patients satisfying the diagnostic criteria of metabolic syndrome as per the IDF criteria (2005) were included in the study, as there are separate cut off points for waist circumference for South Asian population. Design: Cross-sectional observational study. Setting: Single centre study in a tertiary care teaching hospital. Participants: Initially 450 patients with metabolic syndrome as per International Diabetes Federation (IDF) criteria (2005) were screened. Patients having age above 65 years, deranged liver/renal function, ischemic heart disease, heart failure, malignancy, pregnancy, ascitis, poor echo window, history of endocrine disorders like Cushing Syndrome, glucocorticoid use, having any acute illness and those not giving consent were excluded. Final sample size was 397. For defining the normal EAT thickness in this geographic region, 50 age and gender matched healthy volunteers without any conventional cardiovascular risk factors (except age in some cases) acted as controls. Study period was six months. RESULT The mean value of EAT thickness in the control group was 2.97 (± 0.86) mm, hence the upper reference limit of EAT thickness in this study was taken as more than mean + 2SD, i.e. 4.69mm. Mean EAT thickness in patients suffering from metabolic syndrome was 5.48 ± 0.83 mm, which was significantly increased compared to controls. Taking 4.69mm as cut off, it was seen that 311 (78.34%) patients had increased EAT thickness >4.69mm. CONCLUSION Further studies with larger sample size and longitudinal design are required to establish the ability of EAT thickness to predict cardiovascular risk.

PREVALENCE OF METABOLIC SYNDROME IN FIRST EPISODE DRUG NAÏVE SCHIZOPHRENIA PATIENTS

2021 ◽  
pp. 41-43
Author(s):  
Alok Kumar Sinha ◽  
Amitabh Saha ◽  
Chandrima Bhattacharya ◽  
Sanjay Kumar
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Tertiary Care ◽  
First Episode ◽  
Western India ◽  
Care Hospital ◽  
Glucose Levels ◽  
Drug Naïve

BACKGROUND: It is well established that schizophrenia is associated with higher morbidity and mortality due to the nature of illness itself and cardiovascular risk factors. Among cardiovascular risk factors metabolic syndrome has been discussed extensively in psychiatric literature. However most of the studies focused on the recent pharmacological interventions are possible etiological factors of metabolic syndrome. In our study we are trying to nd out any association of metabolic syndrome with schizophrenia in drug naïve patients. METHOD: Eighty consecutive drug naïve rst episode patients with schizophrenia presenting at a tertiary care hospital in Western India were studied. They were assessed for prevalence of metabolic syndrome as per the criteria set by the NCEP (ATPIII) in Adults. RESULT: A high prevalence of metabolic syndrome in drug naïve rst episode patients with schizophrenia was found as compared to that in general population. CONCLUSION: There should be mandatory screening for the possibility of hyperlipidemia, high glucose levels and metabolic syndrome in drug naïve rst episode patients with schizophrenia before prescribing antipsychotic drugs

scholarly journals Relationship between abdominal obesity and other cardiovascular risk factors: cross sectional study of patients with symptomatic carotid disease

2013 ◽  
Vol 141 (7-8) ◽  
pp. 460-465 ◽  
Author(s):  
Milos Maksimovic ◽  
Hristina Vlajinac ◽  
Djordje Radak ◽  
Jelena Marinkovic ◽  
Jadranka Maksimovic ◽  
...  
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Abdominal Obesity ◽  
Carotid Atherosclerosis ◽  
Cross Sectional Study ◽  
Carotid Disease ◽  
Cross Sectional ◽  
Symptomatic Carotid

Introduction. Obesity, particularly visceral obesity, is considered one of major risk factors for cardiovascular events. Objectives. The aim of the present study was to investigate relationship between abdominal obesity and other cardiovascular risk factors. Methods. The cross-sectional study involved 657 consecutive patients with verified carotid atherosclerosis. Carotid atherosclerosis was estimated by high resolution B-mode ultrasonography. Abdominal obesity was defined as waist circumference >102 cm in men and >88 cm in women. Results. Abdominal obesity was present in 324 (49.3%) participants. Multivariate analyses showed that abdominal obesity was significantly positively associated with female sex, increased Baecke ?s Work Index of physical activity at work, years of school completed <12, metabolic syndrome, increased triglycerides, hyperglycemia and high serum uric acid. Smoking, alcohol consumption, physical inactivity, hypertension, increased total cholesterol, increased HDL and LDL cholesterols, increased high sensitive C-reactive protein, increased fibrinogen, anti-lipid therapy and anti-diabetic therapy were not significantly related to abdominal obesity. Conclusion. Abdominal obesity among patients with symptomatic carotid disease is significantly related to other cardiovascular risk factors, especially metabolic syndrome, metabolic syndrome components and high level of serum uric acid.

scholarly journals Metabolic syndrome, insulin resistance and other cardiovascular risk factors in university students

2016 ◽  
Vol 21 (4) ◽  
pp. 1123-1136 ◽  
Author(s):  
José Bonifácio Barbosa ◽  
Alcione Miranda dos Santos ◽  
Marcelo Mesquita Barbosa ◽  
Márcio Mesquita Barbosa ◽  
Carolina Abreu de Carvalho ◽  
...  
Keyword(s):  
Risk Factors ◽  
Insulin Resistance ◽  
Metabolic Syndrome ◽  
Cardiovascular Risk ◽  
University Students ◽  
Cardiovascular Risk Factors ◽  
Hdl Cholesterol ◽  
Blood Collection ◽  
Cross Sectional ◽  
High Blood Glucose

Abstract A cross-sectional population-based study using questionnaire and anthropometric data was conducted on 968 university students of São Luís, Brazil, from which 590 showed up for blood collection. In the statistical analysis the Student t-test, Mann-Whitney and chi-square tests were used. The prevalence of metabolic syndrome by the Joint Interim Statement (JIS) criteria was 20.5%, almost three times more prevalent in men (32.2%) than in women (13.5%) (P < 0.001). The prevalence of insulin resistance was 7.3% and the prevalence of low HDL-cholesterol was high (61.2%), both with no statistically significant differences by sex. Men showed a higher percentage of smoking, overweight, high blood pressure, high blood glucose and increased fasting hypertriglyceridemia. Women were more sedentary. University students of private institutions had higher prevalences of sedentary lifestyle, obesity, abdominal obesity, elevated triglycerides and metabolic syndrome than students from public institutions. High prevalences of metabolic syndrome, insulin resistance and other cardiovascular risk factors were found in this young population. This suggests that the burden of these diseases in the future will be increased.

scholarly journals Association between the Use of Health Services, Cardiovascular Risk Factors and Metabolic Syndrome in Mexican Adults

2021 ◽  
Vol 18 (10) ◽  
pp. 5336
Author(s):  
María Araceli Ortiz-Rodríguez ◽  
María Vanessa Aldaz-Rodríguez ◽  
Luz María González-Robledo ◽  
Antonio Villa ◽  
Cristina Bouzas ◽  
...  
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
Cardiovascular Risk ◽  
Health Services ◽  
Cardiovascular Risk Factors ◽  
Cultural Beliefs ◽  
Cross Sectional ◽  
Medical Diagnoses ◽  
Mexican Adults ◽  
Use Of Health Services

Background: The use of health services is a complex behavioral phenomenon affected by multiple factors (availability, distance, cost, quality, attitudes, cultural beliefs, socioeconomic characteristics, and individuals’ self-perception of health). Mexico has a segmented health system, and the access to it depends on the labor insertion and the population’s ability to pay. Objective: To assess association between use of health services and cardiovascular and metabolic syndrome risk factors among Mexican adults. Methods: Analytical cross-sectional nationally representative study carried out on Mexican adults (≥20-year-old adults of both sexes; n = 4595). Socioeconomic factors, geographic area, health care coverage, information about the use of health services, previous medical diagnoses of diabetes and hypertension, and smoking were assessed. Anthropometrics, triglyceride, total cholesterol, HDL-cholesterol, and glucose plasma levels were measured. Metabolic syndrome (MetS) and cardiovascular risk factors were assessed. Prevalences were expressed in terms of percentages, and significant differences were calculated using χ2 test. Univariate and multivariate analysis was performed to evaluate the association between the use of health services and cardiovascular risk factors and sociodemographic variables. Results: The probability of using health services is higher and more significant in subjects with obesity, diabetes (OR (95% CI): 1.73 (1.49–2.00; p < 0.001), hypertension (OR (95% CI): 1.29 (1.14–1.45; p < 0.001), hypertriglyceridemia (OR (95% CI): 1.30 (1.15–1.46; p < 0.001), and in those with hypercholesterolemia (OR (95% CI): 1.23 (1.03–1.39; p = 0.001). Conclusions: Among health service users, there is a positive significant association between the use of health services and the presence of metabolic syndrome, obesity, diabetes, hypertension, hypertriglyceridemia, and hypercholesterolemia.

scholarly journals Association of Cardiovascular Risk Factors in Hypertensive Subjects with Metabolic Syndrome Defined by Three Different Definitions

2011 ◽  
Vol 51 (184) ◽  
Author(s):  
R Shrestha ◽  
SC Jha ◽  
M Khanal ◽  
P Gyawali ◽  
BK Yadav ◽  
...  
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Disease Risk ◽  
Oxidized Ldl ◽  
International Diabetes Federation ◽  
High Sensitivity ◽  
Cardiac Risk ◽  
Cardiac Risk Factors

Introduction: Different authorities have put forward their criteria to defi ne metabolic syndrome (MetS). The aim of this study was to fi nd the prevalence of MetS in hypertensive individuals by the available three different defi nitions from National Cholesterol Education Program (NCEP), International diabetes Federation (IDF) and WHO and their association with other cardiac risk factors. Methods: After anthropometric measurements fasting blood was analyzed for glucose, lipids, high sensitivity C-reactive protein (hsCRP) and anti-oxidized LDL antibody in 150 hypertensive individuals. A ten-year coronary heart disease risk was predicted using the Framingham risk score (FRS). Results: The prevalence of MetS was 54.7 % by NCEP, 42.0 % by IDF) and 18.7 % by WHO. As many as 63.4 % had MetS by any defi nition, while only 9.4 % fulfi lled all the criteria of the three definitions. The association of cardiac risk factors also varied according to the defi nition used. hsCRP was signifi cantly elevated in MetS compared to non-MetS. Body mass index, waist circumference and HDL-C were associated in MetS defi ned by NCEP and IDF. FRS was higher in MetS defi ned by Adult Treatment Panel and WHO defi nitions. An increase in urine albumin and a decrease in eGFR were associated with MetS individuals defi ned by WHO only. Conclusions: There is a wide variation in the prevalence of MetS and associated cardiac risk factors according to three different defi nitions used. The different cardiac risk factors among MetS also vary with the defi nitions used. However, hsCRP and emerging risk factor are signifi cantly elevated in hypertensive individuals with MetS as defi ned by all defi nitions. Keywords: cardiovascular risk factors, hypertension,metabolic syndrome.

Sign in / Sign up

Export Citation Format

Share Document