scholarly journals COMPARATIVE ANALYSIS OF OSSEOINTEGRATION WITH OR WITHOUT PRF (PLATELET RICH FIBRIN) IN ORAL IMPLANTOLOGY- A RANDOMIZED PROSPECTIVE CLINICAL STUDY

2020 ◽  
pp. 29-32
Author(s):  
Sweta Parna Deb ◽  
Rakesh Ranjan ◽  
Bineet Kumar ◽  
Akash Raj Sharma ◽  
Md Kashif Noorani ◽  
...  

Introduction Dental rehabilitation of partially or totally edentulous patients with dental implants has become a popular treatment modality with reliable long-term results. These days’ new methods are being used to improve the quality of osseointegration. Platelet Rich Fibrin (PRF) is a second generation platelet concentrate which is a new biotechnology, it has been suggested to be of great use in implant dentistry as it can enhance the quality of osseointegration. Various studies show that it improves healing of both hard as well as soft tissues. Aim To compare the quality of osseointegration using platelet rich fibrin over conventional implant placement. Materials & Methods 40 dental implants were placed in total for this study. 20 implants each were placed with PRF (Goup A) and without PRF (Group B) in the osteotomy site. After three months CBCT was done to evaluate and compare the quality of osseointegration between the 2 groups measured in gray value using the Galileos Implant Software- Sirona. Result Mean values obtained were ≈1928 in group A (with PRF) and ≈1734.6 in group B (without PRF). Independent Samples T-Test showed a significant p-value of 0.013 ( p-value>0.05). Conclusion Results from our study show that PRF can play a promising role in the quality of osseointegration when used as a biomaterial in oral implantology. Our study provides a basis for future research with larger sample size and longer follow-ups to elucidate this outcome further.

2014 ◽  
Vol 4 (1) ◽  
pp. 19-21
Author(s):  
NR Sharma ◽  
U Rai ◽  
S Panthee ◽  
P Shrestha

Epidural anaesthesia and analgesia in orthopaedic surgeries helps to prevent thromboembolic phenomenon by increasing venodynamics. Adequate post operative analgesia with good patient satisfaction has been observed with this technique. The objective of this study was to assess the duration of postoperative analgesia and complications in patients receiving epidural anesthesia with morphine, midazolam and pethidine in combination with bupivacaine. We prospectively studied 75 Patients who were scheduled for elective lower limb orthopaedic surgery with epidural anaesthesia. This study was conducted from March 2010 to March 2012 at Lumbini Medical College Palpa. They were randomly divided by lottery method into three equal groups. Group ‘A’ (BP) received 50 mg epidural pethidine (3 ml) with 0.5 % bupivacaine 13 ml. Group ‘ B’ (BM) received 5 mg (3 ml) epidural morphine with 13 ml of 0.5% bupivacaine and Group’ C’ (BMM) received 5 mg (1 ml) epidural morphine with 13 ml 0.5% bupivacaine and 2 mg (2 ml) epidural midazolam. All the patients were observed for 24 hours for quality of analgesia and other side effects like nausea vomiting, and pruritus. Data were analysed by SPSS-16.0 software. The result of the study shows the duration of analgesia was prolonged in BMM group than BM, and BP group and was statistically significant (P value <0.001). Incidence of nausea and vomiting in BMM group was lower than that of BP and BM group but was statistically insignificantly (P value 0.489). Pruritus was absent in BP group and was more with BM and BMM group (P value 0.007). In conclusion the use of epidural morphine and midazolam in combination with bupivacaine is the satisfactory method of post operative analgesia. By adding midazolam, duration of analgesia can be increased with decrease in incidence of nausea, vomiting and pruritus. DOI: http://dx.doi.org/10.3126/jcmc.v4i1.10842 Journal of Chitwan Medical College 2014; 4(1): 19-21


2021 ◽  
Vol 67 (2) ◽  
pp. 40-48
Author(s):  
A. V. Ogorodnikov ◽  
S. S. Kharnas

BACKGROUND. Primary hyperparathyroidism (PGPT) is an increase in the secretory activity of the parathyroid glands (OSH), due to their tumor or hyperplastic changes. Due to the lack of an effective alternative to the treatment of PGPT, the surgical method is still the only correct tactical solution for the management of patients with an established diagnosis of PGPT. The paper presents the long-term results and assessment of the quality of life of patients who underwent surgical treatment from standard and small access. The results obtained showed the promise of a sparing approach to the treatment of PGPT caused by LV adenoma.AIM. To study the effectiveness of surgical treatment of patients with PGPT based on the assessment of the quality of life of patients who underwent parathyroidectomy from standard and small access.MATERIALS AND METHODS. A retrospective study of the quality of life of patients with PGPT after surgical treatment was conducted using the SF-36 questionnaire and the linear analog scale (LAS). Statistical data processing is performed in the R programming language using the FMSB package. The quantitative parameters were presented as median (Median) and interquartile range (25th (1st Qu) — lower quartile and 75th (3rd Qu ) — upper quartile). As a nonparametric statistical criterion, the Mann–Whitney U-test was used, on the basis of which the p-value was calculated. The calculated data of the research results are presented in graphical form — in the form of bar charts, spider plot and barplot.RESULTS. This study involved 264 patients. The patients were divided into 2 groups: GR1 — patients operated from the Kocher access with mandatory revision of all 4 OSH, GR2 — patients who received surgical treatment from the small access with the removal of the altered OSH, without revision of the remaining OSH. When analyzing the quality of life of patients before surgery, there were no statistically significant differences in the groups in terms of PF (Physical Functioning) and VT (Vitality). Small-access parathyroidectomy (patients with GR 2) significantly improved the quality of life in the GH (General Health) and VT (Vitality) domains. The analysis of LAS before surgery between the groups showed no statistically significant differences, while after surgical treatment, the indicators on the linear analog scale differ in the direction of improvement in GR2.CONCLUSION. The results obtained in the course of the study showed the promise of a gentle approach to the treatment of PGPT caused by LV adenoma, which is reflected in higher quality of life indicators.


2011 ◽  
Vol 37 (2) ◽  
pp. 247-257 ◽  
Author(s):  
Amany A. El Hadary ◽  
Hala H. Yassin ◽  
Sameh T. Mekhemer ◽  
Julian C. Holmes ◽  
Martin Grootveld

Abstract Immunosuppressive agents have been recognized as factors that induce changes and modifications in bone metabolism. The purpose of this study was to evaluate the effect of ozonated plant extracts (herein termed ozonated oil) under the influence of Cyclosporin A (CsA) on osseointegration. A total of 20 dental implants were placed in 20 rabbit tibiae assigned to Group A or B. CsA was injected at an immunosuppressive dose in Groups A and B as a single-dose treatment. At the day of surgery, Group A received a single topical ozonated oil treatment (0.55 mL) around dental implants; Group B, the control group, received no ozonated oil. Animals were sacrificed after 8 weeks. Radiographs were obtained at implant surgery and on the day of sacrifice. Bone quality was compared between the 2 groups. Radiographically, osseointegration was microscopically evaluated using scanning electron and light microscopies. In ozonated Group A specimens, light microscopic examination demonstrated evidence of more organized mature bone compared with Group B. Within the limits of this study, the results suggest that short-term administration of CsA, when administered with topical ozonated oil, may influence bone density and the quality of dental implant osseointegration. Therefore, topically applied ozonated oil may influence bone density and the quality of osseointegration around dental implants.


2021 ◽  
Vol 2 (5) ◽  
Author(s):  
André Luiz Ravasoli ◽  
Pedro Ferrari de Paula ◽  
Thaina Regina da Silva ◽  
Elias Naim Kassis

Introduction: Dental implant procedures have reached about one million dental implants per year in the world. In this context, it is necessary to establish the state of the art of minimally traumatic procedures for dental implants, especially after bone graft procedures and/or the use of biomaterials for bone elevation. In this context of optimizing techniques for better management of dental implants, faster and more accurate methods were developed by dentists, with post-operative results with better results and quality of life, through minimally invasive procedures. Objective: To carry out a concise systematic review of minimally traumatic surgery for dental implants, as well as to elucidate the main techniques for this. Methods: The rules of the Systematic Review Platform-PRISMA were followed. The survey was conducted from July 2021 to October 2021 and was developed based on Scopus, PubMed, Science Direct, Scielo, and Google Scholar. Study quality was based on the GRADE instrument and the risk of bias was analyzed according to the Cochrane instrument. Results: Since the most primordial extraction techniques were created and developed, several attempts have been made to minimize the professional's effort, reduce surgical time and alleviate bleeding and inflammatory processes, edema, pain, and ecchymosis that can affect patients, in the trans and postoperative periods. Thus, the maximum preservation of the integrity of the soft tissues (papillae and free and inserted gingival band) adjacent to the prosthetic spaces should be sought; preservation of the alveolar bone ridge level. Based on the histological concept in which living tissues are formed by cells joined by thin elastic tissue and with nerve fibrils, capillaries, lymphatic and blood vessels. The disruption of these cells by surgical trauma provides the release of enzymes that delay healing. For this reason, surgical trauma should be minimized. Conclusion: There are many attempts to minimize the professional effort, reduce surgical time and alleviate bleeding and inflammatory processes, edema, pain, and ecchymosis that can affect patients. Thus, the maximum preservation of the integrity of the soft tissues adjacent to the prosthetic spaces and the preservation of the level of the ridge of the alveolar bone to achieve a minimization of surgical trauma must be sought.


2020 ◽  
Vol 8 (8) ◽  
pp. 513
Author(s):  
Sandeep Dubey ◽  
Rukhsana Najeeb ◽  
Arshid Ahmad Sofi

Background: Supraclavicular block is a safe, reliable and cost effective technique of providing anesthesia for the upper limb surgeries. Objectives:  To evaluate the effect of Clonidine and Dexmedetomidine as an adjuvant to Ropivacaine in ultrasound guided supraclavicular block in upper limb surgeries with respect to: Onset of sensory and motor block, Duration of sensory and motor block, Quality of block and Duration of post-operative analgesia. Materials and methods: The purpose of present study was to compare the effect of addition of clonidine 1mcg/kg vs dexmedetomidine 1mcg/kg to 20ml of 0.5% ropivacaine in ultrasound guided supraclavicular brachial plexus block. A total of 90 patients of ASA I and II, aged 18-60 years, of either gender, undergoing upper limb surgery were allocated to three groups. Each group consisted of 30 patients. They received drugs as under: Group-A (dexmedetomidine group) received 20ml of 0.5% ropivacaine plus 1μg/kg of dexmedetomidine. Group-B (clonidine group) received 20ml of 0.5% ropivacaine plus 1mcg/kg clonidine. Group-C (placebo group) received 20 ml of 0.5% ropivacaine plus 2 ml normal saline. Results: Onset of sensory block was faster in Group-A as compared to Group-B and Group-C. The difference was statistically significant (p-value<0.05). Onset of motor block was faster in Group-A as compared to Group-B and Group C. The difference was statistically significant (p-value<0.05). Patients of Group-A had significantly longer duration of sensory and motor block when compared with Group-B and Group-C (p-value<0.05). Duration of post-operative analgesia was significantly longer in Group-A as compared to Group-B and Group-C (p-value<0.05). Quality of block was significantly better in Group-A as compared to Group-B and Group-C (p-value<0.05). Conclusion: Dexmedetomidine prolongs the duration of sensory and motor block, duration of postoperative analgesia and improves the quality of block much more as compared to clonidine when used as an adjuvant to ropivacaine in supraclavicular brachial plexus block.


2020 ◽  
Vol 11 (3) ◽  
pp. 524-535
Author(s):  
Sapna Sehgal ◽  
Huddar V G ◽  
Mangalagowri V Rao

Introduction: Prakriti has an influential role in diagnosis and management of any disease. Increasing pandemic of diabetes leads to early mortality and decreased quality of life due to severe complications and side effect of contemporary medicines. The present study reveals Prakriti specific combination of herbs in form of tea with antidiabetic effect and no side effects. Materials and methods: 115 patients were enrolled which was randomly distributed in 2 group. Group A was Prakriti specific Herbal tea trial group and Group B was control. Both subjective and objective parameters were assessed. Results:Highly significant results with p value <0.0001 were seen in Polyuria (Prabhutmutrata), Laziness (Alasya), Excess Sleep (Nidraadhikya), Dryness in Mouth(Gala Talu Shosha), Excessive Thirst (Ati Pipasa), with maximum improvement in Polyuria (Prabhutmutrata).Significant results were seen in Burning Sensation in hands and legs (Karpaddaha),Numbness in palm and foot (Karpadasuptata), Cramps (Pindikodweshtana). Highly significant results were seen in Fasting, Postprandial Blood sugar, HbA1c and urine fasting glucose was seen  in Prakriti specific Herbal tea group with p value <0.0001. Maximum improvement were seen in Kapha Prakriti patients with p value < 0.0001 followed by Vata Prakriti patients. Vata and Kapha Herbal Tea found equally effective.Conclusion: Prakriti specific Herbal Tea is a better option of Diabetes Mellitus with high efficacy.


Author(s):  
Ena Sharma ◽  
Amit Lakhani ◽  
Rasveen Kaur ◽  
Ravneet Kaur

This case series reports the various treatment modalities to treat the multiple recessions. Gingival recession is a widespread clinical manifestation affecting single or multiple root surfaces at all teeth types. Periodontal reconstructive surgery consists of various mucogingival procedures. The primary goal of these procedures is to benefit periodontal health through the reconstruction of lost hard and soft tissues, or by preventing its additional loss, and also enhancing the esthetic appearance. Platelet-rich fibrin is a second generation platelet concentrate and is defined as an autologous leukocyte and platelet-rich fibrin biomaterial. Care was taken not to extend the incisions till the tip of the interdental papilla. A full thickness mucoperiosteal flap was reflected, extending beyond the mucogingival junction. A wide range of surgical techniques has been proposed for the treatment of the gingival recessions, each with its advantages and disadvantages. To provide predictable and long-term results, it is of paramount importance that the surgical technique is individually selected, taking into account several crucial factors such as the size of the defect, the width of the keratinised gingiva apical to the defect and the thickness of the flap.


Author(s):  
Ankita Jain ◽  
R Raja ◽  
K Santosh Kumar

Introduction: Osteoarthritis is a common disease of aged population and one of the leading causes of disability. Key causes include obesity or overweight along with aging. Knee osteoarthritis can cause significant pain and functional loss. As the disease progresses, it can cause chronic knee joint pain, muscle weakness, joint deformity and functional deficiency which leads to decreased quality of life. The Western Ontario and McMaster Universities Osteoarthritis (WOMAC) is a 24-item questionnaire with 3 sub-scales measuring pain (5 items), stiffness (2 items) and physical function (17 items). Health related quality of life is measured using Short Form-36, used to examine health status in following eight domains: Bodily pain, physical function, role limitations due to social problems, physical problems, general health, vitality, social function, mental health, role limitation due to physical problems. Aim: To find the effect of Short Form-36 Health Status Questionnaire versus WOMAC Arthritis Index Questionnaire to measure the pain, Range of Motion (ROM) and disability in subjects with chronic knee osteoarthritis patients treated with Contrast Bath and Knee Exercises. Materials and Methods: This study was a pre and post longitudinal cohort study. A total of 90 patients were divided into two groups of 45 each. Each patient was given treatment for four weeks. Each patient was treated with Contrast bath and Knee Exercises. Group A patients were instructed to fill the Short Form-36 Health Status Questionnaire and Group B patients were instructed to fill the WOMAC Arthritis Index Questionnaire and outcome measures were collected on day 1, at the end of 2nd week and at the end of 4th week. Data from study were analysed using the statistical package SPSS 19.0 (SPSS Inc., Chicago, IL) and level of significance was set at p<0.05. Results: Group B shows a mean of the total score of WOMAC Arthritis Index Questionnaire which was 74.66 (SD 10.01) on Day 1; mean of 49.02 (SD 12.08) at the end of the 2nd week and a mean of 20.68 (SD 12.23) at the end of 4th week. The p-value was found to be 0.0001. The percentage disability evaluated by the WOMAC Arthritis Index Questionnaire shows a mean of 78 (SD 10) on Day 1; mean of 51 (SD 12) at the end of 2nd week and a mean of 22 (SD 13) at the end of 4th week. On day 1 Short Form-36 Questionnaire, total score of group A was 88.24 (SD 6.72) and at the end of 2nd week and 4th week the mean score was 94.06 (SD 5.10) and 98.72 (SD 4.55), respectively with statistically significant difference p-value (0.0001). Conclusion: The present study showed that the WOMAC Arthritis Index Questionnaire had superior sensitivity in reducing pain and increasing range of motion and thus by decreasing the disability.


2021 ◽  
Vol 10 (4) ◽  
pp. 3300-3303
Author(s):  
Waqar M. Naqvi

To evaluate the effect of Step aerobic exercises and music therapy on mental health in menopausal women. Menopausal women of selected areas of Belagavi city were screened in a door to door survey using Menopause Quality Of Life (MENQOL) questionnaire. 69 menopausal women who fulfilled the inclusion criteria were divided randomly into 3 groups Group A was administrated Music therapy, for Group B Step Aerobic Exercises was given and Group C was administrated combination of Music therapy and step aerobic exercises. All three groups showed significant changes from pre and post intervention. The p-value for Group A versus Group B between pre-test and post-test was 0.001*.For Group A versus Group C was 0.001* and for Group B versus Group C between pre-test and post-test was 0.906 which was not significant. Step aerobics, music therapy and a combination of both were equally effective in improving the mental health status of post-menopausal women. Any one or combination of them can be used to help improve quality of life in these women.


2020 ◽  
Vol 19 (2) ◽  
pp. 208-217
Author(s):  
Deaa Abdulkhalik Raheem ◽  
◽  
Muqdad Fuad Abdulkareem ◽  
Humamalddin Edan Hussein

Background: Acute appendicitis is the most common emergency condition that faces the surgeon worldwide. The overall lifetime risk of having acute appendicitis is estimated to be 6–7 %, with a peak incidence between 10 and 30 years. Early and sometimes immediate appendicectomy is standard, fearing the risk of pathological progression into perforation, gangrenous appendicitis, and abscess formation. However, recently, this practice has been challenged by authors giving a suggestion that appendicectomies can be delayed in some cases and still devoid of adverse postoperative outcomes. Objective: This study aimed at comparing the two groups regarding the following postoperative outcomes: WBC count on a postoperative day one, time last to a soft liquid diet, rate of complication, length of in-hospital stay, and the need for admission within 30 days of doing the surgery. Patients and Methods: This is a prospective randomized study of 341 patients (196 male and 145 female) who underwent appendicectomy over a period of eleven months (May 2019- March 2020) in Baquba Teaching Hospital in Diyala Governorate. The patients categorized into two groups for making the comparison (all underwent appendectomy): group A: 181 patients (male 108, female 73) include those who are operated on within 8 hours of arrival to the hospital and group B: 160 patients (male 81, female 79) include those who are operated on after 8 hours of arrival to the hospital. The patients in the two groups were compared regarding the following postoperative outcomes as WBC count at day one postoperatively, time duration to a liquid diet, rate of complication, length of in-hospital stay, and finally, the need for readmission during the first 30 days of doing the surgery. Results: Regarding the mean white blood cell count at the first postoperative day, it was lower for group B. than that for group A (p-value 0.0018). With regard to the timing of starting having liquid diet, there was no significant difference, and the patients in the two groups started oral liquid diet within the first 24 hours (p-value 0.0715). There was no significant difference between the two groups regarding the immediate and early postoperative complication rate; 0.02% in group A and 0.37% for group B (p-value 0.4022), the length of postoperative hospital stay was the same for the two groups, ranging between 2 days and less than one day (p value 0.0826). There was no significant difference between the two groups regarding the need for readmission within 30 days, 0.016% in group A and 0.025% in group B (p-value 0.9984). Conclusion: This study concluded that delayed appendicectomy was safe and feasible for patients with uncomplicated appendicitis. Despite that the clinical outcomes of delayed appendicectomy were not better than those with early appendicectomy. Also Delayed appendicectomy can improve the quality of care provided by the residents, surgeons, anesthetists and theater staff, enhance patient's quality of care, and it allows an increased efficient utilization of medical resources and theaters for other life-threatening emergency cases.


Sign in / Sign up

Export Citation Format

Share Document