MORTALITY IN SLE – A RETROSPECTIVE STUDY

2021 ◽  
pp. 5-6
Author(s):  
Bilal Ahmad Rather ◽  
Zubair Ahmad Khuja ◽  
Tariq A Mir

Aims And Objectives:This retrospective study was conducted in SKIMS Soura Srinagar to study co morbidities associated with SLE as well as to analyse pattern of mortality of SLE patients. Methods:We analyzed the data of one decade from Jan 2004 to Dec 2014 for total deaths which occurred in SKIMS soura Srinagar during this period. Files of 133 patients on whom Rheumatic disease was mentioned were separately fully analyzed for patient's age, sex, type of rheumatic disease, any other underlying disease and terminal events which lead to death of patient. Particular attention was paid to data of SLE patients. Observations:There were 41 SLE patients with a male female ratio of 1: 12.6. Mean age at death was 32.46±13.739 years (range 15 – 68). Most of the patients 34 (82.9%) were in the age group of 20-59 years. The main associated co morbidities were HTN in 23 (56.1%), CRF in 20 (48.8%) patients. The common causes of death were sepsis in 12 (29.3%), ARF in 11 (26.8%) , heart failure in 9 (22.0%). Conclusion:We found that Rheumatic disease patients particularly SLE have premature mortality compared to the non Rheumatic patients and sepsis being the leading cause of death in SLE patients. Mortally of SLE is bimodal with an early mortality due to disease ares and a late mortality due to disease plus other associated co-morbidities like DM, HTN, Malignancy and cardiovascular conditions.

2013 ◽  
Vol 10 (3) ◽  
pp. 39-43 ◽  
Author(s):  
Uma Devi Chhetri ◽  
I Ansari ◽  
S Shrestha

Background Kerosene, drugs, pesticides are chemicals used in home and farms. But because of parents’ or caretakers’ negligence; accidents and poisoning in children may take life of a child. Objective  To study the common causes and outcome of pediatric accident and poisoning cases admitted in Patan Hospital.Method A prospective (2068-69) and retrospective (2066-67) studies of pediatric accident and poisoning cases admitted in Patan Hospital (2066-chaitra 2069) were done. Result Out of 44 registered cases total 35 cases were collected in last 4 years. Twenty one in prospective and 14 in retrospective study. Male female ratio was 1.2:1. Most vulnerable age group was 1-5 years (21) and 11-15 yrs (8). Most common poison was pesticide (11), kerosene (9) and drugs (7).  Twenty percent were suicidal, 3% were homicidal and rest was accidental. Suicidal poisoning was common in 11-14 years. Accidental poisoning was: taking kerosene from mineral water bottle for water. Small children took drugs and pesticides due its easy availability or careless storing.  Five common accidents were near drowning (2), hot water scald, hanging and fall from height. Outcome was 2 expired; 1 Organo-phosphorous and 1 food poisoning. Mortality was 6%. One hanging survived as vegetation. Conclusion Accident and poisoning are preventable. We need to make our home and surrounding poison and accident proof. Small children should never be left unattended. Drugs, pesticides, hot things, and sharp instruments should be kept out of reach of children and in child proof container in separate places. Pesticide should not be sold to children. Kathmandu University Medical Journal | VOL.10 | NO. 3 | ISSUE 39 | JUL- SEP 2012 | Page 39-43 DOI: http://dx.doi.org/10.3126/kumj.v10i3.8016


1970 ◽  
Vol 16 (1) ◽  
pp. 3-8
Author(s):  
Delwar Hossain ◽  
Mosleh Uddin ◽  
Ahmmad Taous ◽  
Kazi Shameemus Salam ◽  
Rafiqul Islam

Canal wall window (CWW) tympanomastoidectomy is a modified form of attico-antrostomywhich can be a substituted for canal wall down procedure. A retrospective study of 84 casesof CWW tympanomastoidectomy were collected from department of otolaryngology and Headnecksurgery, BSMMU and ENT Foundation Hospital, Dhaka from June 2005 to July 2009.In this study majority of the patients were 16 to 48 years 57(67.86%). Male female ratio was3:1. Most of the patients were found cholesteatoma 27 (32.14%), granulation tissue 25(29.76%),retraction pocket 22(26.19%),Postoperative hearing gain (mean three frequency pure tone air bone gap) assessed 3 monthsafter primary surgery, most of the patients 34(40.48%) had gain 20dB+, 26 patients (30.95%)had gain 10dB+,18 patients (2143%) had gain 30dB+.Materials used in tympano-ossiculoplasty were chonchal cartilage, sculptured incus, PORPand TORP. Most of the patients we used incus reposition 36(42.86%), cartilage ossiculoplasty28(33.33%), PORP 12(14.29%) and TORP 8 (9.52%).Post operative followup of the patient was done in 1 month, 3 month and 6 month intervals andcondition of external auditory canal assessed. Dry ear were found 70 patients (83.33%), moistear were found 8 patients (9.52%) and 6 patients (7.14%) were found purulent dischargingears and later canal wall down mastoidectomy done .Key words: Canal wall window; Tympanomastoidectomy.DOI: 10.3329/bjo.v16i1.5774Bangladesh J Otorhinolaryngol 2010; 16(1): 3-8


2021 ◽  
Vol 9 ◽  
Author(s):  
Min Da ◽  
Bo Qian ◽  
Xuming Mo ◽  
Cheng Xu ◽  
Haiyan Wu ◽  
...  

Background: Inflammatory myofibroblastic tumor (IMFT) is a rare neoplasm mainly affecting children and young adults. We conducted a retrospective study to evaluate the clinical features and treatment alternatives of childhood inflammatory myofibroblastic tumors.Methods: A total of 19 patients who were pathologically diagnosed with IMT between December 2008 and October 2018 were included. Collected data were demographic information, main complaints, tumor characteristics, treatment, pathological results, immunohistochemical analysis, and prognosis.Results: The male/female ratio was 13:6. The mean age at disease onset was 44.9 ± 33.9 months (range 4 to 111 months). The mean tumor size was 6.5 ± 4.0 cm (range 1.2 to 17.0 cm). The most common site was the abdomen (13/19). The most commonly used detection tool was CT. Eleven patients (57.9%) had aggressive tumor growth, including eight receiving extensive resection and three receiving palliative resection due to high local invasiveness and postoperative chemotherapy. Eight cases whose tumors were completely enveloped received complete resection. Immunohistochemistry was performed for 17 patients and ALK positivity was found in 11 patients. Despite three children lost to follow-up, sixteen patients were followed up for 6 to 132 months (average 63.9 months, median 66 months). Of which, twelve children survived with no evidence of IMT, and four cases (21%) showed local recurrences (two of them died). No distant metastasis was detected.Conclusions: IMT is rare in children with various locations, mostly appearing in the abdomen. Whether the tumor could be completely removed, the location and the invasiveness of surrounding tissues might be highly prognosis-related.


Author(s):  
Rukma L. Sharma ◽  
Rekha Sharma

<p class="abstract"><strong>Background:</strong> Herpes zoster results from the reactivation of varicella-zoster virus lying dormant in the dorsal root ganglia following an earlier primary infection (chickenpox), usually in childhood. The reactivation occurs due to multifactorial causes leading to decreased immunity.</p><p class="abstract"><strong>Methods:</strong> This study was conducted on 109 cases of herpes zoster. Patient’s particulars were noted. A detailed history was recorded; morphology, the site and side of skin lesions were recorded. Any other associated diseases were noted.<strong></strong></p><p class="abstract"><strong>Results:</strong> Out of 109 patients 66 were male and 43 were female. The total of 53 (48.6%) patients were under the age of 40 years and 56 (51.4%) patients above 40 years. Bhutias were affected in highest number (18.4%) followed by Sharma community (15.6%). The ophthalmic division of trigeminal nerve was the most commonly affected single nerve with 13.8% followed by T10 and T7 dermatome at 9.17% and 7.3% respectively. Thoracic nerves the most commonly involved thoracic nerves with 44 cases. Single dermatomal eruptions were found in 55 patients. The dissemination of herpes zoster was although very rare but was present in three patients. Type 2 diabetes mellitus was the common associated systemic illness with 10.09% of patients.</p><p class="abstract"><strong>Conclusions:</strong> From this study it was revealed that both young adults and older age group people were affected almost equally. The male: female ratio was 1.5:1 with Bhutia community being mostly affected. Thoracic dermatome was the most common dermatome involved and in half the patients some form of associated disease noted.</p>


2015 ◽  
Vol 22 (06) ◽  
pp. 798-803
Author(s):  
Mariam Arif

Introduction: There are three types of compression of neck which are of primeforensic importance – (1) Manual strangulation (2) Hanging (3) Ligature strangulation. Ligaturemark is found in the latter two types.1 Ligature mark is a pressure mark on the neck underneaththe ligature. Initially it appears as a pale groove which on drying becomes yellowish brownparchment like.2,5 Objective: The aim is to study the information provided by a ligature markin ligature asphyxial deaths. Methodology: Study Design: A retrospective study on ligatureasphyxial deaths. Setting: Forensic Medicine and Toxicology Departments of King EdwardMedical University, Lahore and Nishtar Medical College, Multan. Period: January, 2012 toDecember, 2013. Results: The incidence of violent ligature asphyxial deaths was 4.21% of thetotal medicolegal deaths autopsied. Age group 21 to 30 years accounted for the maximumcases (37.6%). Male: female ratio was 1.02. Nylon rope (44.7%) was the most common ligaturematerial used. Ligature mark was single in all cases and was situated above thyroid cartilage in82.92% cases of hanging. In ligature strangulation deaths, mark was one in number in 93.18%cases and was below thyroid cartilage in 97.72% cases. The manner of death in hangingwas mostly suicidal (90.24%) as compared to homicidal in all cases of ligature strangulation.Ligature mark was incompletely encircling the neck in 85.36% cases and obliquely present in100% cases of hanging. In all deaths due to ligature strangulation, it was completely encirclingand transversely present around the neck. Underlying soft tissues of neck were glisteningwhite in all hanging deaths while it showed extravasations of blood in all ligature strangulationcases. Conclusions: A meticulous examination of the ligature mark during autopsy, though notconclusive, can give valuable information that can be very helpful in diagnosing deaths due tohanging and ligature strangulation.


Author(s):  
Preet Kamal ◽  
Ripan Bala ◽  
Madhu Nagpal ◽  
Harleen Kaur

Background: Adenomyosis and leiomyoma are the common causes of abnormal uterine bleeding (AUB). In this study it is aimed to evaluate the correlation of clinical and histopathological examination (HPE) of these entities leading to abnormal uterine bleeding.Methods: This retrospective study was carried out on hysterectomy specimens of subjects who presented themselves in the department of obstetrics and gynaecology of Sri Guru Ram Das Institute of medical sciences and research, Amritsar with chief complaints of AUB not responding to conservative treatment.Results: A total of 100 women with clinical diagnosis of AUB in which hysterectomies were performed, leiomyoma was found in 42% cases, adenomyosis in 22% cases. The most frequent combination of diagnosis was leiomyoma and adenomyosis i.e. 26%. In 9% cases chronic cervicitis and ovarian cyst were detected. In one case endometrial malignancy was found.Conclusions: Though adenomyosis and leiomyoma are clinically diagnosed along with other pathological conditions of the reproductive organs but their confirmation is still to be relied upon HPE; a most important investigation.


2016 ◽  
Vol 8 ◽  
pp. OED.S39055 ◽  
Author(s):  
Abdulrahman Darraj ◽  
Walid Barakat ◽  
Mona Kenani ◽  
Reem Shajry ◽  
Abdullah Khawaji ◽  
...  

Background The rise in childhood eye diseases has become a matter of concern in Saudi Arabia, and hence a study has been conducted on the residents of Jazan. The aim of the research was to find out the root cause of such issues and provide a solution to prevent such circumstances for it may affect the vision of children. In this study, therefore, we aimed to determine the types of childhood eye diseases in Jazan and to discuss the best ways to prevent them or prevent their effect on the vision of our children. Our institutions are working toward the longevity and welfare of the residents, and healthcare is one of the important aspects in such a field. Methods This is a retrospective review of all patients less than 18 years of age who presented to the pediatric ophthalmology clinic of Prince Mohammed Bin Nasser Hospital, Jazan, between October 2014 and October 2015. The data, collected on 385 cases, included the age at first presentation, sex, clinical diagnosis, refractive error (RE) if present, and whether the child had amblyopia. If the child did not undergo complete ophthalmic examination with cycloplegic refraction, he/she was excluded. All data were collected and analyzed using the software SPSS. A P-value < 0.05 was considered statistically significant. Results We reviewed the files of 385 children, with a male/female ratio of 1.1:1.0. The group aged 0–6 years made up the largest group ( P = 0.01), and the ratio is an expression to define the credibility of the study using a chi-squared test. Strabismus (36.9%), RE (26.5%), ocular trauma (7.5%), infection of cornea and conjunctiva (7.3%), and keratoconus (6.2%) were the most common conditions. There was no significant difference in presentation by age group and sex among children with REs and squint. Trauma was seen more commonly among males and in the group aged 12–18 years. Conclusion In this retrospective study, the focus was on the common childhood eye diseases that were considerably high. Hypermetropia was the predominant RE, which is in contrast to other studies where myopia was more common. However, it is important to promote public education on the significance of early detection of strabismus, REs, and amblyopia and have periodic screening in schools. The discussion of the various issues is aimed at increasing the awareness and building a support for the cause by creating the knowledge base to treat things on time and acknowledging the severity of the issues.


2021 ◽  
Vol 31 (1) ◽  
pp. e39374
Author(s):  
Pasionaria Rosa Ramos Ruiz Diaz ◽  
Gladys Velázquez ◽  
Elder Oliveira da Silva ◽  
Claudia Carolina Centurión Viveros ◽  
Roberto Esperanza Dullack Peña ◽  
...  

Aims: This study aimed to describe the epidemiological characteristics of COVID-19 cases diagnosed in quarantine facilities in Paraguay.Methods: This was a descriptive, cross-sectional, temporarily retrospective study. The time scope was from April 1 to September 30 2020. The variables were sex, age and administrative departments. The open access data available on the website of the Ministry of Public Health and Social Welfare was used. Frequencies expressed in percentages and the Chi square value were calculated to observe the statistically significant differences between cases and age and sex.Results: from April 4 to September 30 2020, 1.581 cases were diagnosed in COVID-19. The fewest number of positive cases were reported in April (50) and the highest number was reported in May (628). From the total, 69.6% (1.101) were male, (male / female ratio 2.3), 42.1% (666) were aged between 20-29 years, the average age was 30.23 years (range 0 to 87, standard deviation 14.66. 95% CI 1.5 - 58.95). The departments with the highest number of cases were Caaguazú 21.7 % (343), Alto Paraná 17.3 % (274), Central 13.3% (210) and Asunción 11.4% (180). The least number of cases of COVID-10 in women were registered in the Departments of Amambay, Pdte. Hayes, Ñeembucú and Boquerón, and in men the Departments of Ñeembucú and Boquerón. The largest number of male cases were registered in Caaguazú 70.8% (243), Alto Paraná 66.1% (181), Central 69.5% (146) and Asunción 68.9% (124). The number of Covid-19 infected people in quarantine facilities presented statistically significant differences between the variables sex and age.Conclusion: the quarantine facilities are one of the measures that the Paraguayan government needed to avoid the rapid spread and dispersion of the virus. The epidemiology of the cases diagnosed in them corresponds to what was expected according to the characteristics of the country.


2013 ◽  
Vol 2 (1) ◽  
pp. 29-33
Author(s):  
Mahbuba Hossen ◽  
Mazharul Alam Siddique ◽  
Nahid Binte Ansary

This retrospective study was done in the Department of Dentistry, CBMC’B hospital from January’2009 to December’2010. 223 patients who underwent RCT were purposively selected. Male-female ratio was 1:1.4, mean age of patients were 28.4 years. Most common indication of RCT was gross caries 69.95%, common complications were fractured crown 11(57.89%), tenderness 5(26.32%), discharging sinus 2(10.53%). Over all success rate of RCT was 91.48%. DOI: http://dx.doi.org/10.3329/cbmj.v2i1.14178 Community Based Medical Journal Vol.2(1) 2013 29-33


2018 ◽  
Vol 5 (6) ◽  
pp. 2283
Author(s):  
Balaji Dhanaram ◽  
Sakthivel Chandrasekar ◽  
Baskar Muthukumaraswamy

Background: Abdominal pain is a very prevalent problem in children and one of the common causes for visit to the hospital. They may be of acute or chronic presentation and depending on severity may also require admission to hospital.Methods: This is a retrospective study conducted in our hospital over a period of 3 years. About 200 children who came to the hospital with abdominal pain and received treatment in surgical outpatient or referred to surgery department from emergency were included in this study and all relevant data were collected.Results: The pain was found to be more in boys and in the age group of 9 to 12years. The most common cause was found to be mesenteric adenitis followed by acute appendicitis. About 38% of children required surgical intervention on that admission due to various surgical causes.Conclusions: The database of our retrospective study regarding age and sex incidence, clinicopathological features and therapeutic outcome was comparable to other studies in various literatures.


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